Antibodies Antibodies were procured and used for immunohistochemistry (IHC) and Western blot (WB) analysis as follows: mAB 3B6 (a kind gift from Dr. R.S. Molday, University of British Columbia, Vancouver, BC, Canada, IHC-1∶100); RDS-CT recognizing both endogenous Rds and, to a lesser extent, NMP (generated in-house, IHC-1∶100, WB-1∶1000); anti-S-opsin, recognizing short-wavelength mouse cone opsin (generated in-house, IHC-1∶100, WB-1∶1000); mAb 1D4, recognizing rhodopsin (a generous gift from Dr. R.S. Molday, WB-1∶5000); Rom-1 (generated in-house, WB-1∶1000); and β-actin-HRP (Sigma/Aldrich, WB-1∶5000).