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PMC:2664230 / 2711-3055 JSONTXT

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bionlp-st-ge-2016-reference

Id Subject Object Predicate Lexical cue
T1133 36-46 Negative_regulation denotes attenuated
T1134 241-245 Positive_regulation denotes lead
T1135 253-267 Negative_regulation denotes downregulation
T1136 271-276 Protein denotes TNF-α
T1137 277-287 Gene_expression denotes production
T1131 13-18 Protein denotes TNF-α
T1132 19-28 Gene_expression denotes synthesis
R835 T1131 T1132 themeOf TNF-α,synthesis
R836 T1132 T1133 themeOf synthesis,attenuated
R837 T1135 T1134 themeOf downregulation,lead
R838 T1136 T1137 themeOf TNF-α,production
R839 T1137 T1135 themeOf production,downregulation

2_test

Id Subject Object Predicate Lexical cue
18568240-2460096-22101114 169-170 2460096 denotes 4

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T1699 0-11 RB denotes Furthermore
T1700 11-12 -COMMA- denotes ,
T1701 13-18 NN denotes TNF-α
T1702 19-28 NN denotes synthesis
T1703 29-32 MD denotes can
T1704 33-35 VB denotes be
T1705 36-46 VB denotes attenuated
T1706 47-49 IN denotes in
T1707 50-56 JJ denotes immune
T1708 57-62 NN denotes cells
T1709 63-70 VB denotes exposed
T1710 71-73 TO denotes to
T1711 74-91 NN denotes phosphodiesterase
T1712 92-93 -LRB- denotes (
T1713 93-96 NN denotes PDE
T1714 96-97 -RRB- denotes )
T1715 98-108 NN denotes inhibition
T1716 109-114 IN denotes after
T1717 115-124 NN denotes challenge
T1718 125-127 IN denotes by
T1719 128-129 DT denotes a
T1720 130-137 NN denotes variety
T1721 138-140 IN denotes of
T1722 141-157 JJ denotes pro-inflammatory
T1723 158-170 NN denotes stimulants.4
T1724 171-174 DT denotes The
T1725 175-184 NN denotes signaling
T1726 185-195 NN denotes mechanisms
T1727 196-204 VB denotes affected
T1728 205-207 IN denotes by
T1729 208-211 NN denotes PDE
T1730 212-222 NN denotes inhibition
T1731 222-223 -COMMA- denotes ,
T1732 224-229 WDT denotes which
T1733 230-240 RB denotes ultimately
T1734 241-245 VB denotes lead
T1735 246-248 TO denotes to
T1736 249-252 DT denotes the
T1737 253-267 NN denotes downregulation
T1738 268-270 IN denotes of
T1739 271-276 NN denotes TNF-α
T1740 277-287 NN denotes production
T1741 287-288 -COMMA- denotes ,
T1742 289-293 VB denotes have
T1743 294-297 RB denotes not
T1744 298-302 VB denotes been
T1745 303-307 RB denotes well
T1746 308-321 VB denotes characterized
T1747 322-324 IN denotes in
T1748 325-337 JJ denotes inflammatory
T1749 338-343 NN denotes cells
R1387 T1702 T1701 arg1Of synthesis,TNF-α
R1388 T1702 T1703 arg1Of synthesis,can
R1389 T1702 T1704 arg1Of synthesis,be
R1390 T1702 T1705 arg2Of synthesis,attenuated
R1391 T1705 T1703 arg2Of attenuated,can
R1392 T1705 T1704 arg2Of attenuated,be
R1393 T1705 T1706 arg1Of attenuated,in
R1394 T1705 T1716 arg1Of attenuated,after
R1395 T1708 T1706 arg2Of cells,in
R1396 T1708 T1707 arg1Of cells,immune
R1397 T1708 T1709 arg2Of cells,exposed
R1398 T1709 T1710 arg1Of exposed,to
R1399 T1711 T1712 arg1Of phosphodiesterase,(
R1400 T1713 T1712 arg2Of PDE,(
R1401 T1714 T1712 arg3Of ),(
R1402 T1715 T1710 arg2Of inhibition,to
R1403 T1715 T1711 arg1Of inhibition,phosphodiesterase
R1404 T1717 T1716 arg2Of challenge,after
R1405 T1717 T1718 arg1Of challenge,by
R1406 T1720 T1718 arg2Of variety,by
R1407 T1720 T1719 arg1Of variety,a
R1408 T1720 T1721 arg1Of variety,of
R1409 T1723 T1721 arg2Of stimulants.4,of
R1410 T1723 T1722 arg1Of stimulants.4,pro-inflammatory
R1411 T1726 T1724 arg1Of mechanisms,The
R1412 T1726 T1725 arg1Of mechanisms,signaling
R1413 T1726 T1727 arg2Of mechanisms,affected
R1414 T1726 T1731 arg1Of mechanisms,","
R1415 T1726 T1732 arg1Of mechanisms,which
R1416 T1726 T1734 arg1Of mechanisms,lead
R1417 T1726 T1742 arg1Of mechanisms,have
R1418 T1726 T1744 arg1Of mechanisms,been
R1419 T1726 T1746 arg2Of mechanisms,characterized
R1420 T1730 T1727 arg1Of inhibition,affected
R1421 T1730 T1728 arg2Of inhibition,by
R1422 T1730 T1729 arg1Of inhibition,PDE
R1423 T1734 T1733 arg1Of lead,ultimately
R1424 T1734 T1735 arg1Of lead,to
R1425 T1737 T1735 arg2Of downregulation,to
R1426 T1737 T1736 arg1Of downregulation,the
R1427 T1737 T1738 arg1Of downregulation,of
R1428 T1740 T1738 arg2Of production,of
R1429 T1740 T1739 arg1Of production,TNF-α
R1430 T1746 T1699 arg1Of characterized,Furthermore
R1431 T1746 T1700 arg1Of characterized,","
R1432 T1746 T1703 modOf characterized,can
R1433 T1746 T1741 arg1Of characterized,","
R1434 T1746 T1742 arg2Of characterized,have
R1435 T1746 T1743 arg1Of characterized,not
R1436 T1746 T1744 arg2Of characterized,been
R1437 T1746 T1745 arg1Of characterized,well
R1438 T1746 T1747 arg1Of characterized,in
R1439 T1749 T1747 arg2Of cells,in
R1440 T1749 T1748 arg1Of cells,inflammatory

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T1253 0-11 RB denotes Furthermore
T1254 11-12 , denotes ,
T1255 13-18 JJ denotes TNF-α
T1256 19-28 NN denotes synthesis
T1257 29-32 MD denotes can
T1258 33-35 VB denotes be
T1259 36-46 VBN denotes attenuated
T1260 47-49 IN denotes in
T1261 50-56 JJ denotes immune
T1262 57-62 NNS denotes cells
T1263 63-70 VBN denotes exposed
T1264 71-73 TO denotes to
T1265 74-91 VB denotes phosphodiesterase
T1266 92-93 -LRB- denotes (
T1267 93-96 NNP denotes PDE
T1268 96-97 -RRB- denotes )
T1269 98-108 NN denotes inhibition
T1270 109-114 IN denotes after
T1271 115-124 NN denotes challenge
T1272 125-127 IN denotes by
T1273 128-129 DT denotes a
T1274 130-137 NN denotes variety
T1275 138-140 IN denotes of
T1276 141-157 JJ denotes pro-inflammatory
T1277 158-168 NNS denotes stimulants
T1278 168-170 CD denotes .4
T1279 171-174 DT denotes The
T1280 175-184 VBG denotes signaling
T1281 185-195 NNS denotes mechanisms
T1282 196-204 VBN denotes affected
T1283 205-207 IN denotes by
T1284 208-211 NNP denotes PDE
T1285 212-222 NN denotes inhibition
T1286 222-223 , denotes ,
T1287 224-229 WDT denotes which
T1288 230-240 RB denotes ultimately
T1289 241-245 VBP denotes lead
T1290 246-248 TO denotes to
T1291 249-252 DT denotes the
T1292 253-267 NN denotes downregulation
T1293 268-270 IN denotes of
T1294 271-276 JJ denotes TNF-α
T1295 277-287 NN denotes production
T1296 287-288 , denotes ,
T1297 289-293 VBP denotes have
T1298 294-297 RB denotes not
T1299 298-302 VBN denotes been
T1300 303-307 RB denotes well
T1301 308-321 VBN denotes characterized
T1302 322-324 IN denotes in
T1303 325-337 JJ denotes inflammatory
T1304 338-343 NNS denotes cells
T1305 343-344 . denotes .
R939 T1253 T1259 advmod Furthermore,attenuated
R940 T1254 T1259 punct ",",attenuated
R941 T1255 T1256 amod TNF-α,synthesis
R942 T1256 T1259 nsubjpass synthesis,attenuated
R943 T1257 T1259 aux can,attenuated
R944 T1258 T1259 auxpass be,attenuated
R945 T1259 T1259 ROOT attenuated,attenuated
R946 T1260 T1259 prep in,attenuated
R947 T1261 T1262 amod immune,cells
R948 T1262 T1260 pobj cells,in
R949 T1263 T1259 conj exposed,attenuated
R950 T1264 T1265 aux to,phosphodiesterase
R951 T1265 T1263 advcl phosphodiesterase,exposed
R952 T1266 T1267 punct (,PDE
R953 T1267 T1265 appos PDE,phosphodiesterase
R954 T1268 T1259 punct ),attenuated
R955 T1269 T1301 nsubjpass inhibition,characterized
R956 T1270 T1269 prep after,inhibition
R957 T1271 T1270 pobj challenge,after
R958 T1272 T1271 prep by,challenge
R959 T1273 T1274 det a,variety
R960 T1274 T1272 pobj variety,by
R961 T1275 T1274 prep of,variety
R962 T1276 T1277 amod pro-inflammatory,stimulants
R963 T1277 T1275 pobj stimulants,of
R964 T1278 T1271 nummod .4,challenge
R965 T1279 T1281 det The,mechanisms
R966 T1280 T1281 amod signaling,mechanisms
R967 T1281 T1301 nsubjpass mechanisms,characterized
R968 T1282 T1281 acl affected,mechanisms
R969 T1283 T1282 agent by,affected
R970 T1284 T1285 compound PDE,inhibition
R971 T1285 T1283 pobj inhibition,by
R972 T1286 T1285 punct ",",inhibition
R973 T1287 T1289 nsubj which,lead
R974 T1288 T1289 advmod ultimately,lead
R975 T1289 T1285 relcl lead,inhibition
R976 T1290 T1289 prep to,lead
R977 T1291 T1292 det the,downregulation
R978 T1292 T1290 pobj downregulation,to
R979 T1293 T1292 prep of,downregulation
R980 T1294 T1295 compound TNF-α,production
R981 T1295 T1293 pobj production,of
R982 T1296 T1301 punct ",",characterized
R983 T1297 T1301 aux have,characterized
R984 T1298 T1301 neg not,characterized
R985 T1299 T1301 auxpass been,characterized
R986 T1300 T1301 advmod well,characterized
R987 T1301 T1301 ROOT characterized,characterized
R988 T1302 T1301 prep in,characterized
R989 T1303 T1304 amod inflammatory,cells
R990 T1304 T1302 pobj cells,in
R991 T1305 T1301 punct .,characterized

GO-BP

Id Subject Object Predicate Lexical cue
T2134 19-28 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T2140 271-287 http://purl.obolibrary.org/obo/GO_0032640 denotes TNF-α production
T2144 271-287 http://purl.obolibrary.org/obo/GO_0032680 denotes TNF-α production
T2149 74-91 http://purl.obolibrary.org/obo/GO_0008081 denotes phosphodiesterase
T2150 93-96 http://purl.obolibrary.org/obo/GO_0004114 denotes PDE
T2151 208-211 http://purl.obolibrary.org/obo/GO_0004114 denotes PDE
T2155 175-184 http://purl.obolibrary.org/obo/GO_0023052 denotes signaling
T2157 253-276 http://purl.obolibrary.org/obo/GO_1904468 denotes downregulation of TNF-α

GO-MF

Id Subject Object Predicate Lexical cue
T2194 74-91 http://purl.obolibrary.org/obo/GO_0008081 denotes phosphodiesterase
T2195 93-96 http://purl.obolibrary.org/obo/GO_0004114 denotes PDE
T2196 208-211 http://purl.obolibrary.org/obo/GO_0004114 denotes PDE

GO-CC

Id Subject Object Predicate Lexical cue
T2222 57-62 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T2223 338-343 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

sentences

Id Subject Object Predicate Lexical cue
T1152 0-344 Sentence denotes Furthermore, TNF-α synthesis can be attenuated in immune cells exposed to phosphodiesterase (PDE) inhibition after challenge by a variety of pro-inflammatory stimulants.4 The signaling mechanisms affected by PDE inhibition, which ultimately lead to the downregulation of TNF-α production, have not been well characterized in inflammatory cells.
T26 0-344 Sentence denotes Furthermore, TNF-α synthesis can be attenuated in immune cells exposed to phosphodiesterase (PDE) inhibition after challenge by a variety of pro-inflammatory stimulants.4 The signaling mechanisms affected by PDE inhibition, which ultimately lead to the downregulation of TNF-α production, have not been well characterized in inflammatory cells.

events-check-again

Id Subject Object Predicate Lexical cue
T2374 13-18 Protein denotes TNF-α
T2375 19-28 Gene_expression denotes synthesis
T2376 36-46 Negative_regulation denotes attenuated
T2377 241-245 Positive_regulation denotes lead
T2378 253-267 Negative_regulation denotes downregulation
T2379 271-276 Protein denotes TNF-α
T2380 277-287 Gene_expression denotes production
R1834 T2374 T2375 themeOf TNF-α,synthesis
R1836 T2375 T2376 themeOf synthesis,attenuated
R1838 T2378 T2377 themeOf downregulation,lead
R1839 T2379 T2380 themeOf TNF-α,production
R1840 T2380 T2378 themeOf production,downregulation

bionlp-st-ge-2016-reference-tees

Id Subject Object Predicate Lexical cue
T2242 13-18 Protein denotes TNF-α
T2243 93-96 Protein denotes PDE
T2244 271-276 Protein denotes TNF-α
T2245 74-91 Protein denotes phosphodiesterase
T2246 19-28 Gene_expression denotes synthesis
T2247 36-46 Negative_regulation denotes attenuated
T2248 98-108 Negative_regulation denotes inhibition
T2249 98-108 Negative_regulation denotes inhibition
T2250 277-287 Gene_expression denotes production
T2251 253-267 Negative_regulation denotes downregulation
R1754 T2242 T2246 themeOf TNF-α,synthesis
R1755 T2243 T2248 themeOf PDE,inhibition
R1756 T2244 T2250 themeOf TNF-α,production
R1757 T2245 T2249 themeOf phosphodiesterase,inhibition
R1758 T2246 T2247 themeOf synthesis,attenuated
R1759 T2250 T2251 themeOf production,downregulation

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T2048 13-16 P01375 denotes TNF
T2049 13-18 P01375 denotes TNF-α
T2050 271-274 P01375 denotes TNF
T2051 271-276 P01375 denotes TNF-α

test2

Id Subject Object Predicate Lexical cue
T1108 13-18 Protein denotes TNF-α
T1109 19-28 Gene_expression denotes synthesis
T1110 36-46 Negative_regulation denotes attenuated
T1111 253-267 Negative_regulation denotes downregulation
T1112 271-276 Protein denotes TNF-α
T1113 277-287 Gene_expression denotes production
R823 T1108 T1109 themeOf TNF-α,synthesis
R824 T1109 T1110 themeOf synthesis,attenuated
R825 T1112 T1113 themeOf TNF-α,production
R826 T1113 T1111 themeOf production,downregulation