PMC:2664230 / 24091-24290 JSONTXT

{"project":"bionlp-st-ge-2016-reference","denotations":[{"id":"T8366","span":{"begin":163,"end":173},"obj":"Negative_regulation"},{"id":"T8367","span":{"begin":174,"end":179},"obj":"Protein"},{"id":"T8368","span":{"begin":185,"end":198},"obj":"Transcription"}],"relations":[{"id":"R6826","pred":"themeOf","subj":"T8367","obj":"T8368"},{"id":"R6827","pred":"themeOf","subj":"T8368","obj":"T8366"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"Given these relationships, it is conceivable that PTX may exert some of its anti-inflammatory actions by affecting AP-1 activation and favoring CREB binding, thus inhibiting TNF-α gene transcription."}

{"project":"bionlp-st-ge-2016-spacy-parsed","denotations":[{"id":"T9539","span":{"begin":0,"end":5},"obj":"VBN"},{"id":"T9540","span":{"begin":6,"end":11},"obj":"DT"},{"id":"T9541","span":{"begin":12,"end":25},"obj":"NNS"},{"id":"T9542","span":{"begin":25,"end":26},"obj":","},{"id":"T9543","span":{"begin":27,"end":29},"obj":"PRP"},{"id":"T9544","span":{"begin":30,"end":32},"obj":"VBZ"},{"id":"T9545","span":{"begin":33,"end":44},"obj":"JJ"},{"id":"T9546","span":{"begin":45,"end":49},"obj":"IN"},{"id":"T9547","span":{"begin":50,"end":53},"obj":"NNP"},{"id":"T9548","span":{"begin":54,"end":57},"obj":"MD"},{"id":"T9549","span":{"begin":58,"end":63},"obj":"VB"},{"id":"T9550","span":{"begin":64,"end":68},"obj":"DT"},{"id":"T9551","span":{"begin":69,"end":71},"obj":"IN"},{"id":"T9552","span":{"begin":72,"end":75},"obj":"PRP$"},{"id":"T9553","span":{"begin":76,"end":93},"obj":"JJ"},{"id":"T9554","span":{"begin":94,"end":101},"obj":"NNS"},{"id":"T9555","span":{"begin":102,"end":104},"obj":"IN"},{"id":"T9556","span":{"begin":105,"end":114},"obj":"VBG"},{"id":"T9557","span":{"begin":115,"end":119},"obj":"JJ"},{"id":"T9558","span":{"begin":120,"end":130},"obj":"NN"},{"id":"T9559","span":{"begin":131,"end":134},"obj":"CC"},{"id":"T9560","span":{"begin":135,"end":143},"obj":"VBG"},{"id":"T9561","span":{"begin":144,"end":148},"obj":"NNP"},{"id":"T9562","span":{"begin":149,"end":156},"obj":"JJ"},{"id":"T9563","span":{"begin":156,"end":157},"obj":","},{"id":"T9564","span":{"begin":158,"end":162},"obj":"RB"},{"id":"T9565","span":{"begin":163,"end":173},"obj":"VBG"},{"id":"T9566","span":{"begin":174,"end":179},"obj":"JJ"},{"id":"T9567","span":{"begin":180,"end":184},"obj":"NN"},{"id":"T9568","span":{"begin":185,"end":198},"obj":"NN"},{"id":"T9569","span":{"begin":198,"end":199},"obj":"."}],"relations":[{"id":"R7960","pred":"prep","subj":"T9539","obj":"T9544"},{"id":"R7961","pred":"det","subj":"T9540","obj":"T9541"},{"id":"R7962","pred":"pobj","subj":"T9541","obj":"T9539"},{"id":"R7963","pred":"punct","subj":"T9542","obj":"T9544"},{"id":"R7964","pred":"nsubj","subj":"T9543","obj":"T9544"},{"id":"R7965","pred":"ROOT","subj":"T9544","obj":"T9544"},{"id":"R7966","pred":"acomp","subj":"T9545","obj":"T9544"},{"id":"R7967","pred":"mark","subj":"T9546","obj":"T9549"},{"id":"R7968","pred":"nsubj","subj":"T9547","obj":"T9549"},{"id":"R7969","pred":"aux","subj":"T9548","obj":"T9549"},{"id":"R7970","pred":"ccomp","subj":"T9549","obj":"T9544"},{"id":"R7971","pred":"dobj","subj":"T9550","obj":"T9549"},{"id":"R7972","pred":"prep","subj":"T9551","obj":"T9550"},{"id":"R7973","pred":"poss","subj":"T9552","obj":"T9554"},{"id":"R7974","pred":"amod","subj":"T9553","obj":"T9554"},{"id":"R7975","pred":"pobj","subj":"T9554","obj":"T9551"},{"id":"R7976","pred":"prep","subj":"T9555","obj":"T9554"},{"id":"R7977","pred":"pcomp","subj":"T9556","obj":"T9555"},{"id":"R7978","pred":"amod","subj":"T9557","obj":"T9558"},{"id":"R7979","pred":"dobj","subj":"T9558","obj":"T9556"},{"id":"R7980","pred":"cc","subj":"T9559","obj":"T9556"},{"id":"R7981","pred":"conj","subj":"T9560","obj":"T9556"},{"id":"R7982","pred":"dobj","subj":"T9561","obj":"T9560"},{"id":"R7983","pred":"conj","subj":"T9562","obj":"T9560"},{"id":"R7984","pred":"punct","subj":"T9563","obj":"T9549"},{"id":"R7985","pred":"advmod","subj":"T9564","obj":"T9565"},{"id":"R7986","pred":"advcl","subj":"T9565","obj":"T9549"},{"id":"R7987","pred":"amod","subj":"T9566","obj":"T9568"},{"id":"R7988","pred":"compound","subj":"T9567","obj":"T9568"},{"id":"R7989","pred":"dobj","subj":"T9568","obj":"T9565"},{"id":"R7990","pred":"punct","subj":"T9569","obj":"T9544"}],"text":"Given these relationships, it is conceivable that PTX may exert some of its anti-inflammatory actions by affecting AP-1 activation and favoring CREB binding, thus inhibiting TNF-α gene transcription."}

{"project":"GO-BP","denotations":[{"id":"T9863","span":{"begin":185,"end":198},"obj":"http://purl.obolibrary.org/obo/GO_0006351"}],"text":"Given these relationships, it is conceivable that PTX may exert some of its anti-inflammatory actions by affecting AP-1 activation and favoring CREB binding, thus inhibiting TNF-α gene transcription."}

{"project":"GO-MF","denotations":[{"id":"T10058","span":{"begin":149,"end":156},"obj":"http://purl.obolibrary.org/obo/GO_0005488"}],"text":"Given these relationships, it is conceivable that PTX may exert some of its anti-inflammatory actions by affecting AP-1 activation and favoring CREB binding, thus inhibiting TNF-α gene transcription."}

{"project":"sentences","denotations":[{"id":"T8405","span":{"begin":0,"end":199},"obj":"Sentence"},{"id":"T161","span":{"begin":0,"end":199},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Given these relationships, it is conceivable that PTX may exert some of its anti-inflammatory actions by affecting AP-1 activation and favoring CREB binding, thus inhibiting TNF-α gene transcription."}

{"project":"events-check-again","denotations":[{"id":"T10649","span":{"begin":163,"end":173},"obj":"Negative_regulation"},{"id":"T10650","span":{"begin":174,"end":179},"obj":"Protein"},{"id":"T10651","span":{"begin":185,"end":198},"obj":"Transcription"}],"relations":[{"id":"R8512","pred":"themeOf","subj":"T10650","obj":"T10651"},{"id":"R8513","pred":"themeOf","subj":"T10651","obj":"T10649"}],"text":"Given these relationships, it is conceivable that PTX may exert some of its anti-inflammatory actions by affecting AP-1 activation and favoring CREB binding, thus inhibiting TNF-α gene transcription."}

{"project":"bionlp-st-ge-2016-reference-tees","denotations":[{"id":"T10281","span":{"begin":50,"end":53},"obj":"Protein"},{"id":"T10282","span":{"begin":115,"end":119},"obj":"Protein"},{"id":"T10283","span":{"begin":144,"end":148},"obj":"Protein"},{"id":"T10284","span":{"begin":174,"end":184},"obj":"Protein"},{"id":"T10285","span":{"begin":120,"end":130},"obj":"Positive_regulation"},{"id":"T10286","span":{"begin":149,"end":156},"obj":"Binding"},{"id":"T10287","span":{"begin":185,"end":198},"obj":"Transcription"},{"id":"T10288","span":{"begin":105,"end":114},"obj":"Regulation"},{"id":"T10289","span":{"begin":135,"end":143},"obj":"Positive_regulation"},{"id":"T10290","span":{"begin":163,"end":173},"obj":"Negative_regulation"}],"relations":[{"id":"R8299","pred":"causeOf","subj":"T10281","obj":"T10288"},{"id":"R8301","pred":"causeOf","subj":"T10281","obj":"T10290"},{"id":"R8302","pred":"themeOf","subj":"T10282","obj":"T10285"},{"id":"R8304","pred":"themeOf","subj":"T10283","obj":"T10286"},{"id":"R8306","pred":"themeOf","subj":"T10284","obj":"T10287"},{"id":"R8307","pred":"themeOf","subj":"T10285","obj":"T10288"},{"id":"R8309","pred":"themeOf","subj":"T10286","obj":"T10289"},{"id":"R8310","pred":"themeOf","subj":"T10287","obj":"T10290"}],"text":"Given these relationships, it is conceivable that PTX may exert some of its anti-inflammatory actions by affecting AP-1 activation and favoring CREB binding, thus inhibiting TNF-α gene transcription."}

{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T9794","span":{"begin":115,"end":119},"obj":"P05412"},{"id":"T9795","span":{"begin":144,"end":148},"obj":"O43889"},{"id":"T9796","span":{"begin":144,"end":148},"obj":"P15336"},{"id":"T9797","span":{"begin":144,"end":148},"obj":"P16220"},{"id":"T9798","span":{"begin":144,"end":148},"obj":"P18848"},{"id":"T9799","span":{"begin":144,"end":148},"obj":"Q02930"},{"id":"T9800","span":{"begin":144,"end":148},"obj":"Q8TEY5"},{"id":"T9801","span":{"begin":174,"end":177},"obj":"P01375"},{"id":"T9802","span":{"begin":174,"end":179},"obj":"P01375"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"Given these relationships, it is conceivable that PTX may exert some of its anti-inflammatory actions by affecting AP-1 activation and favoring CREB binding, thus inhibiting TNF-α gene transcription."}

{"project":"test2","denotations":[{"id":"T8265","span":{"begin":163,"end":173},"obj":"Negative_regulation"},{"id":"T8266","span":{"begin":174,"end":179},"obj":"Protein"},{"id":"T8267","span":{"begin":185,"end":198},"obj":"Transcription"}],"relations":[{"id":"R6768","pred":"themeOf","subj":"T8266","obj":"T8267"},{"id":"R6769","pred":"themeOf","subj":"T8267","obj":"T8265"}],"text":"Given these relationships, it is conceivable that PTX may exert some of its anti-inflammatory actions by affecting AP-1 activation and favoring CREB binding, thus inhibiting TNF-α gene transcription."}