PMC:2664230 / 20850-21146
Annnotations
bionlp-st-ge-2016-reference
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T8325 | 53-66 | Negative_regulation | denotes | downregulates |
T8326 | 53-66 | Negative_regulation | denotes | downregulates |
T8327 | 53-66 | Negative_regulation | denotes | downregulates |
T8328 | 79-84 | Protein | denotes | I-κBα |
T8329 | 85-100 | Phosphorylation | denotes | phosphorylation |
T8330 | 116-119 | Protein | denotes | p65 |
T8331 | 120-135 | Phosphorylation | denotes | phosphorylation |
T8332 | 136-149 | Localization | denotes | translocation |
T8333 | 274-279 | Protein | denotes | I-κBα |
T8334 | 280-295 | Phosphorylation | denotes | phosphorylation |
R6802 | T8328 | T8329 | themeOf | I-κBα,phosphorylation |
R6803 | T8329 | T8326 | themeOf | phosphorylation,downregulates |
R6804 | T8330 | T8331 | themeOf | p65,phosphorylation |
R6805 | T8330 | T8332 | themeOf | p65,translocation |
R6806 | T8331 | T8325 | themeOf | phosphorylation,downregulates |
R6807 | T8332 | T8327 | themeOf | translocation,downregulates |
R6808 | T8333 | T8334 | themeOf | I-κBα,phosphorylation |
bionlp-st-ge-2016-spacy-parsed
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T9008 | 0-2 | IN | denotes | In |
T9009 | 3-7 | DT | denotes | this |
T9010 | 8-11 | NN | denotes | set |
T9011 | 12-14 | IN | denotes | of |
T9012 | 15-26 | NNS | denotes | experiments |
T9013 | 26-27 | , | denotes | , |
T9014 | 28-30 | PRP | denotes | we |
T9015 | 31-43 | VBD | denotes | demonstrated |
T9016 | 44-48 | IN | denotes | that |
T9017 | 49-52 | NNP | denotes | PTX |
T9018 | 53-66 | VBZ | denotes | downregulates |
T9019 | 67-78 | JJ | denotes | cytoplasmic |
T9020 | 79-84 | JJ | denotes | I-κBα |
T9021 | 85-100 | NN | denotes | phosphorylation |
T9022 | 100-101 | , | denotes | , |
T9023 | 102-109 | JJ | denotes | nuclear |
T9024 | 110-115 | NNP | denotes | NF-κB |
T9025 | 116-119 | CD | denotes | p65 |
T9026 | 120-149 | NN | denotes | phosphorylation/translocation |
T9027 | 149-150 | , | denotes | , |
T9028 | 151-153 | RB | denotes | as |
T9029 | 154-158 | RB | denotes | well |
T9030 | 159-161 | IN | denotes | as |
T9031 | 162-167 | NNP | denotes | NF-κB |
T9032 | 168-179 | NNP | denotes | DNA-binding |
T9033 | 180-185 | IN | denotes | after |
T9034 | 186-189 | NNP | denotes | LPS |
T9035 | 190-201 | NN | denotes | stimulation |
T9036 | 201-202 | , | denotes | , |
T9037 | 203-213 | VBG | denotes | suggesting |
T9038 | 214-218 | IN | denotes | that |
T9039 | 219-222 | NNP | denotes | PTX |
T9040 | 223-229 | VBZ | denotes | exerts |
T9041 | 230-233 | PRP$ | denotes | its |
T9042 | 234-242 | NN | denotes | function |
T9043 | 243-251 | NN | denotes | proximal |
T9044 | 252-254 | TO | denotes | to |
T9045 | 255-257 | CC | denotes | or |
T9046 | 258-260 | IN | denotes | at |
T9047 | 261-264 | DT | denotes | the |
T9048 | 265-270 | NN | denotes | level |
T9049 | 271-273 | IN | denotes | of |
T9050 | 274-279 | JJ | denotes | I-κBα |
T9051 | 280-295 | NN | denotes | phosphorylation |
T9052 | 295-296 | . | denotes | . |
R7429 | T9008 | T9015 | prep | In,demonstrated |
R7430 | T9009 | T9010 | det | this,set |
R7431 | T9010 | T9008 | pobj | set,In |
R7432 | T9011 | T9010 | prep | of,set |
R7433 | T9012 | T9011 | pobj | experiments,of |
R7434 | T9013 | T9015 | punct | ",",demonstrated |
R7435 | T9014 | T9015 | nsubj | we,demonstrated |
R7436 | T9015 | T9015 | ROOT | demonstrated,demonstrated |
R7437 | T9016 | T9018 | mark | that,downregulates |
R7438 | T9017 | T9018 | nsubj | PTX,downregulates |
R7439 | T9018 | T9015 | ccomp | downregulates,demonstrated |
R7440 | T9019 | T9021 | nmod | cytoplasmic,phosphorylation |
R7441 | T9020 | T9021 | amod | I-κBα,phosphorylation |
R7442 | T9021 | T9018 | dobj | phosphorylation,downregulates |
R7443 | T9022 | T9021 | punct | ",",phosphorylation |
R7444 | T9023 | T9026 | amod | nuclear,phosphorylation/translocation |
R7445 | T9024 | T9026 | nmod | NF-κB,phosphorylation/translocation |
R7446 | T9025 | T9026 | nummod | p65,phosphorylation/translocation |
R7447 | T9026 | T9021 | appos | phosphorylation/translocation,phosphorylation |
R7448 | T9027 | T9026 | punct | ",",phosphorylation/translocation |
R7449 | T9028 | T9030 | advmod | as,as |
R7450 | T9029 | T9030 | advmod | well,as |
R7451 | T9030 | T9026 | cc | as,phosphorylation/translocation |
R7452 | T9031 | T9032 | compound | NF-κB,DNA-binding |
R7453 | T9032 | T9033 | compound | DNA-binding,after |
R7454 | T9033 | T9018 | prep | after,downregulates |
R7455 | T9034 | T9035 | compound | LPS,stimulation |
R7456 | T9035 | T9033 | pobj | stimulation,after |
R7457 | T9036 | T9018 | punct | ",",downregulates |
R7458 | T9037 | T9018 | advcl | suggesting,downregulates |
R7459 | T9038 | T9040 | mark | that,exerts |
R7460 | T9039 | T9040 | nsubj | PTX,exerts |
R7461 | T9040 | T9037 | ccomp | exerts,suggesting |
R7462 | T9041 | T9043 | poss | its,proximal |
R7463 | T9042 | T9043 | compound | function,proximal |
R7464 | T9043 | T9040 | dobj | proximal,exerts |
R7465 | T9044 | T9043 | prep | to,proximal |
R7466 | T9045 | T9044 | cc | or,to |
R7467 | T9046 | T9040 | prep | at,exerts |
R7468 | T9047 | T9048 | det | the,level |
R7469 | T9048 | T9046 | pobj | level,at |
R7470 | T9049 | T9048 | prep | of,level |
R7471 | T9050 | T9051 | amod | I-κBα,phosphorylation |
R7472 | T9051 | T9049 | pobj | phosphorylation,of |
R7473 | T9052 | T9015 | punct | .,demonstrated |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T9916 | 85-100 | http://purl.obolibrary.org/obo/GO_0016310 | denotes | phosphorylation |
T9917 | 120-135 | http://purl.obolibrary.org/obo/GO_0016310 | denotes | phosphorylation |
T9918 | 280-295 | http://purl.obolibrary.org/obo/GO_0016310 | denotes | phosphorylation |
GO-MF
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10049 | 168-179 | http://purl.obolibrary.org/obo/GO_0003677 | denotes | DNA-binding |
T10053 | 172-179 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T8389 | 0-296 | Sentence | denotes | In this set of experiments, we demonstrated that PTX downregulates cytoplasmic I-κBα phosphorylation, nuclear NF-κB p65 phosphorylation/translocation, as well as NF-κB DNA-binding after LPS stimulation, suggesting that PTX exerts its function proximal to or at the level of I-κBα phosphorylation. |
T145 | 0-296 | Sentence | denotes | In this set of experiments, we demonstrated that PTX downregulates cytoplasmic I-κBα phosphorylation, nuclear NF-κB p65 phosphorylation/translocation, as well as NF-κB DNA-binding after LPS stimulation, suggesting that PTX exerts its function proximal to or at the level of I-κBα phosphorylation. |
events-check-again
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10608 | 53-66 | Negative_regulation | denotes | downregulates |
T10609 | 53-66 | Negative_regulation | denotes | downregulates |
T10610 | 53-66 | Negative_regulation | denotes | downregulates |
T10611 | 79-84 | Protein | denotes | I-κBα |
T10612 | 85-100 | Phosphorylation | denotes | phosphorylation |
T10613 | 116-119 | Protein | denotes | p65 |
T10614 | 120-135 | Phosphorylation | denotes | phosphorylation |
T10615 | 136-149 | Localization | denotes | translocation |
T10616 | 274-279 | Protein | denotes | I-κBα |
T10617 | 280-295 | Phosphorylation | denotes | phosphorylation |
R8470 | T10611 | T10612 | themeOf | I-κBα,phosphorylation |
R8477 | T10612 | T10609 | themeOf | phosphorylation,downregulates |
R8479 | T10613 | T10614 | themeOf | p65,phosphorylation |
R8480 | T10613 | T10615 | themeOf | p65,translocation |
R8481 | T10614 | T10608 | themeOf | phosphorylation,downregulates |
R8482 | T10615 | T10610 | themeOf | translocation,downregulates |
R8483 | T10616 | T10617 | themeOf | I-κBα,phosphorylation |
bionlp-st-ge-2016-reference-tees
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10192 | 81-84 | Protein | denotes | κBα |
T10193 | 116-119 | Protein | denotes | p65 |
T10194 | 162-167 | Protein | denotes | NF-κB |
T10195 | 219-222 | Protein | denotes | PTX |
T10196 | 274-279 | Protein | denotes | I-κBα |
T10197 | 85-100 | Phosphorylation | denotes | phosphorylation |
T10198 | 102-109 | Entity | denotes | nuclear |
T10199 | 120-149 | Phosphorylation | denotes | phosphorylation/translocation |
T10200 | 168-179 | Binding | denotes | DNA-binding |
T10201 | 280-295 | Phosphorylation | denotes | phosphorylation |
T10202 | 53-66 | Negative_regulation | denotes | downregulates |
T10203 | 53-66 | Negative_regulation | denotes | downregulates |
T10204 | 53-66 | Negative_regulation | denotes | downregulates |
T10205 | 265-270 | Positive_regulation | denotes | level |
R8263 | T10192 | T10197 | themeOf | κBα,phosphorylation |
R8264 | T10193 | T10199 | themeOf | p65,phosphorylation/translocation |
R8265 | T10194 | T10200 | themeOf | NF-κB,DNA-binding |
R8267 | T10196 | T10201 | themeOf | I-κBα,phosphorylation |
R8268 | T10197 | T10202 | themeOf | phosphorylation,downregulates |
R8269 | T10198 | T10199 | Site | nuclear,phosphorylation/translocation |
R8270 | T10199 | T10203 | themeOf | phosphorylation/translocation,downregulates |
R8271 | T10200 | T10204 | themeOf | DNA-binding,downregulates |
R8273 | T10201 | T10205 | themeOf | phosphorylation,level |
bionlp-st-ge-2016-uniprot
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T9740 | 116-119 | Q04206 | denotes | p65 |
T9741 | 116-119 | P21579 | denotes | p65 |
test2
Id | Subject | Object | Predicate | Lexical cue | Negation |
---|---|---|---|---|---|
T8226 | 53-66 | Negative_regulation | denotes | downregulates | |
T8227 | 79-84 | Protein | denotes | I-κBα | |
T8228 | 85-100 | Phosphorylation | denotes | phosphorylation | |
T8229 | 116-119 | Protein | denotes | p65 | |
T8230 | 120-135 | Phosphorylation | denotes | phosphorylation | |
T8231 | 136-149 | Localization | denotes | translocation | |
T8232 | 172-179 | Binding | denotes | binding | true |
T8233 | 274-279 | Protein | denotes | I-κBα | |
T8234 | 280-295 | Phosphorylation | denotes | phosphorylation | |
R6740 | T8227 | T8228 | themeOf | I-κBα,phosphorylation | |
R6741 | T8228 | T8226 | themeOf | phosphorylation,downregulates | |
R6742 | T8229 | T8232 | themeOf | p65,binding | |
R6743 | T8229 | T8231 | themeOf | p65,translocation | |
R6744 | T8229 | T8230 | themeOf | p65,phosphorylation | |
R6745 | T8230 | T8226 | themeOf | phosphorylation,downregulates | |
R6746 | T8231 | T8226 | themeOf | translocation,downregulates | |
R6747 | T8232 | T8226 | themeOf | binding,downregulates | |
R6748 | T8233 | T8234 | themeOf | I-κBα,phosphorylation |