PMC:2664230 / 16822-16965 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue	Negation
T7602	27-41	Negative_regulation	denotes	downregulation
T7603	45-50	Protein	denotes	TNF-α
T7604	51-61	Gene_expression	denotes	production
T7605	131-142	Regulation	denotes	independent	true
R6270	T7602	T7605	themeOf	downregulation,independent
R6271	T7603	T7604	themeOf	TNF-α,production
R6272	T7604	T7602	themeOf	production,downregulation

Id	Subject	Object	Predicate	Lexical cue
T7873	0-5	DT	denotes	These
T7874	6-13	NN	denotes	results
T7875	14-21	VB	denotes	suggest
T7876	22-26	IN	denotes	that
T7877	27-41	NN	denotes	downregulation
T7878	42-44	IN	denotes	of
T7879	45-50	NN	denotes	TNF-α
T7880	51-61	NN	denotes	production
T7881	62-64	IN	denotes	by
T7882	65-68	NN	denotes	PTX
T7883	69-71	IN	denotes	in
T7884	72-86	JJ	denotes	LPS-stimulated
T7885	87-98	JJ	denotes	mononuclear
T7886	99-104	NN	denotes	cells
T7887	105-107	VB	denotes	is
T7888	107-108	-COMMA-	denotes	,
T7889	109-111	IN	denotes	at
T7890	112-117	JJ	denotes	least
T7891	118-120	IN	denotes	in
T7892	121-125	NN	denotes	part
T7893	125-126	-COMMA-	denotes	,
T7894	127-142	JJ	denotes	PKA-independent
R6535	T7874	T7873	arg1Of	results,These
R6536	T7874	T7875	arg1Of	results,suggest
R6537	T7877	T7878	arg1Of	downregulation,of
R6538	T7877	T7883	arg1Of	downregulation,in
R6539	T7877	T7887	arg1Of	downregulation,is
R6540	T7880	T7878	arg2Of	production,of
R6541	T7880	T7879	arg1Of	production,TNF-α
R6542	T7880	T7881	arg1Of	production,by
R6543	T7882	T7881	arg2Of	PTX,by
R6544	T7886	T7883	arg2Of	cells,in
R6545	T7886	T7884	arg1Of	cells,LPS-stimulated
R6546	T7886	T7885	arg1Of	cells,mononuclear
R6547	T7887	T7875	arg2Of	is,suggest
R6548	T7887	T7876	arg1Of	is,that
R6549	T7887	T7888	arg1Of	is,","
R6550	T7887	T7891	arg1Of	is,in
R6551	T7887	T7893	arg1Of	is,","
R6552	T7890	T7889	arg1Of	least,at
R6553	T7891	T7890	arg1Of	in,least
R6554	T7892	T7891	arg2Of	part,in
R6555	T7894	T7887	arg2Of	PKA-independent,is

Id	Subject	Object	Predicate	Lexical cue
T7732	0-5	DT	denotes	These
T7733	6-13	NNS	denotes	results
T7734	14-21	VBP	denotes	suggest
T7735	22-26	IN	denotes	that
T7736	27-41	NN	denotes	downregulation
T7737	42-44	IN	denotes	of
T7738	45-50	JJ	denotes	TNF-α
T7739	51-61	NN	denotes	production
T7740	62-64	IN	denotes	by
T7741	65-68	NNP	denotes	PTX
T7742	69-71	IN	denotes	in
T7743	72-86	JJ	denotes	LPS-stimulated
T7744	87-98	NN	denotes	mononuclear
T7745	99-104	NNS	denotes	cells
T7746	105-107	VBZ	denotes	is
T7747	107-108	,	denotes	,
T7748	109-111	IN	denotes	at
T7749	112-117	JJS	denotes	least
T7750	118-120	IN	denotes	in
T7751	121-125	NN	denotes	part
T7752	125-126	,	denotes	,
T7753	127-142	JJ	denotes	PKA-independent
T7754	142-143	.	denotes	.
R6394	T7732	T7733	det	These,results
R6395	T7733	T7734	nsubj	results,suggest
R6396	T7734	T7734	ROOT	suggest,suggest
R6397	T7735	T7746	mark	that,is
R6398	T7736	T7746	nsubj	downregulation,is
R6399	T7737	T7736	prep	of,downregulation
R6400	T7738	T7739	compound	TNF-α,production
R6401	T7739	T7737	pobj	production,of
R6402	T7740	T7739	prep	by,production
R6403	T7741	T7740	pobj	PTX,by
R6404	T7742	T7736	prep	in,downregulation
R6405	T7743	T7745	amod	LPS-stimulated,cells
R6406	T7744	T7745	compound	mononuclear,cells
R6407	T7745	T7742	pobj	cells,in
R6408	T7746	T7734	ccomp	is,suggest
R6409	T7747	T7746	punct	",",is
R6410	T7748	T7749	advmod	at,least
R6411	T7749	T7750	advmod	least,in
R6412	T7750	T7746	prep	in,is
R6413	T7751	T7750	pobj	part,in
R6414	T7752	T7753	punct	",",PKA-independent
R6415	T7753	T7746	acomp	PKA-independent,is
R6416	T7754	T7734	punct	.,suggest

Id	Subject	Object	Predicate	Lexical cue
T7913	45-61	http://purl.obolibrary.org/obo/GO_0032680	denotes	TNF-α production
T7917	45-61	http://purl.obolibrary.org/obo/GO_0032640	denotes	TNF-α production
T7921	127-130	http://purl.obolibrary.org/obo/GO_0004691	denotes	PKA
T7923	27-50	http://purl.obolibrary.org/obo/GO_1904468	denotes	downregulation of TNF-α

Id	Subject	Object	Predicate	Lexical cue
T7947	127-130	http://purl.obolibrary.org/obo/GO_0004691	denotes	PKA

Id	Subject	Object	Predicate	Lexical cue
T7951	127-130	http://purl.obolibrary.org/obo/GO_0005952	denotes	PKA
T7956	99-104	http://purl.obolibrary.org/obo/GO_0005623	denotes	cells

Id	Subject	Object	Predicate	Lexical cue
T7610	0-143	Sentence	denotes	These results suggest that downregulation of TNF-α production by PTX in LPS-stimulated mononuclear cells is, at least in part, PKA-independent.
T129	0-143	Sentence	denotes	These results suggest that downregulation of TNF-α production by PTX in LPS-stimulated mononuclear cells is, at least in part, PKA-independent.

Id	Subject	Object	Predicate	Lexical cue	Negation
T7973	27-41	Negative_regulation	denotes	downregulation
T7974	45-50	Protein	denotes	TNF-α
T7975	51-61	Gene_expression	denotes	production
T7976	131-142	Regulation	denotes	independent	true
R6583	T7973	T7976	themeOf	downregulation,independent
R6584	T7974	T7975	themeOf	TNF-α,production
R6585	T7975	T7973	themeOf	production,downregulation

Id	Subject	Object	Predicate	Lexical cue
T7997	45-50	Protein	denotes	TNF-α
T7998	65-68	Protein	denotes	PTX
T7999	127-130	Protein	denotes	PKA
T8000	51-61	Gene_expression	denotes	production
T8001	27-41	Negative_regulation	denotes	downregulation
T8002	131-142	Negative_regulation	denotes	independent
R6595	T7997	T8000	themeOf	TNF-α,production
R6596	T7998	T8001	causeOf	PTX,downregulation
R6597	T7999	T8002	causeOf	PKA,independent
R6598	T8000	T8001	themeOf	production,downregulation
R6599	T8001	T8002	themeOf	downregulation,independent

Id	Subject	Object	Predicate	Lexical cue
T7903	45-48	P01375	denotes	TNF
T7904	45-50	P01375	denotes	TNF-α

Id	Subject	Object	Predicate	Lexical cue	Negation
T7583	27-41	Negative_regulation	denotes	downregulation
T7584	45-50	Protein	denotes	TNF-α	true
T7585	51-61	Gene_expression	denotes	production
R6256	T7584	T7585	themeOf	TNF-α,production
R6257	T7585	T7583	themeOf	production,downregulation