PMC:2664230 / 1615-1899
Annnotations
pmc-enju-pas
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T693 | 0-10 | NN | denotes | DISCUSSION |
T694 | 11-14 | DT | denotes | The |
T695 | 15-24 | VB | denotes | increased |
T696 | 25-30 | NN | denotes | level |
T697 | 31-33 | IN | denotes | of |
T698 | 34-38 | NN | denotes | cAMP |
T699 | 39-43 | WDT | denotes | that |
T700 | 44-51 | VB | denotes | results |
T701 | 52-56 | IN | denotes | from |
T702 | 57-74 | NN | denotes | phosphodiesterase |
T703 | 75-85 | NN | denotes | inhibition |
T704 | 86-93 | VB | denotes | affects |
T705 | 94-105 | JJ | denotes | cytoplasmic |
T706 | 106-109 | CC | denotes | and |
T707 | 110-117 | JJ | denotes | nuclear |
T708 | 118-124 | NN | denotes | events |
T709 | 124-125 | -COMMA- | denotes | , |
T710 | 126-135 | VB | denotes | resulting |
T711 | 136-138 | IN | denotes | in |
T712 | 139-142 | DT | denotes | the |
T713 | 143-154 | NN | denotes | attenuation |
T714 | 155-157 | IN | denotes | of |
T715 | 158-163 | NN | denotes | NF-κB |
T716 | 164-167 | CC | denotes | and |
T717 | 168-171 | DT | denotes | the |
T718 | 172-182 | NN | denotes | activation |
T719 | 183-185 | IN | denotes | of |
T720 | 186-190 | NN | denotes | CREB |
T721 | 191-206 | JJ | denotes | transcriptional |
T722 | 207-210 | NN | denotes | DNA |
T723 | 211-218 | NN | denotes | binding |
T724 | 219-226 | IN | denotes | through |
T725 | 227-235 | NN | denotes | pathways |
T726 | 236-240 | WDT | denotes | that |
T727 | 241-244 | VB | denotes | are |
T728 | 245-254 | RB | denotes | partially |
T729 | 255-262 | NN | denotes | Protein |
T730 | 263-269 | NN | denotes | kinase |
T731 | 270-283 | JJ | denotes | A-independent |
R584 | T696 | T694 | arg1Of | level,The |
R585 | T696 | T695 | arg2Of | level,increased |
R586 | T696 | T697 | arg1Of | level,of |
R587 | T696 | T699 | arg1Of | level,that |
R588 | T696 | T700 | arg1Of | level,results |
R589 | T696 | T704 | arg1Of | level,affects |
R590 | T698 | T697 | arg2Of | cAMP,of |
R591 | T700 | T701 | arg1Of | results,from |
R592 | T703 | T701 | arg2Of | inhibition,from |
R593 | T703 | T702 | arg1Of | inhibition,phosphodiesterase |
R594 | T704 | T709 | arg1Of | affects,"," |
R595 | T704 | T710 | modOf | affects,resulting |
R596 | T705 | T706 | arg1Of | cytoplasmic,and |
R597 | T707 | T706 | arg2Of | nuclear,and |
R598 | T708 | T704 | arg2Of | events,affects |
R599 | T708 | T705 | arg1Of | events,cytoplasmic |
R600 | T708 | T707 | arg1Of | events,nuclear |
R601 | T710 | T711 | arg1Of | resulting,in |
R602 | T710 | T724 | arg1Of | resulting,through |
R603 | T713 | T712 | arg1Of | attenuation,the |
R604 | T713 | T714 | arg1Of | attenuation,of |
R605 | T713 | T716 | arg1Of | attenuation,and |
R606 | T715 | T714 | arg2Of | NF-κB,of |
R607 | T716 | T711 | arg2Of | and,in |
R608 | T718 | T716 | arg2Of | activation,and |
R609 | T718 | T717 | arg1Of | activation,the |
R610 | T718 | T719 | arg1Of | activation,of |
R611 | T723 | T719 | arg2Of | binding,of |
R612 | T723 | T720 | arg1Of | binding,CREB |
R613 | T723 | T721 | arg1Of | binding,transcriptional |
R614 | T723 | T722 | arg1Of | binding,DNA |
R615 | T725 | T724 | arg2Of | pathways,through |
R616 | T725 | T726 | arg1Of | pathways,that |
R617 | T725 | T727 | arg1Of | pathways,are |
R618 | T725 | T731 | arg1Of | pathways,A-independent |
R619 | T727 | T728 | arg1Of | are,partially |
R620 | T731 | T727 | arg2Of | A-independent,are |
R621 | T731 | T729 | arg1Of | A-independent,Protein |
R622 | T731 | T730 | arg1Of | A-independent,kinase |
bionlp-st-ge-2016-spacy-parsed
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T385 | 0-10 | NNP | denotes | DISCUSSION |
T386 | 11-14 | NNP | denotes | The |
T387 | 15-24 | VBD | denotes | increased |
T388 | 25-30 | NN | denotes | level |
T389 | 31-33 | IN | denotes | of |
T390 | 34-38 | NNP | denotes | cAMP |
T391 | 39-43 | WDT | denotes | that |
T392 | 44-51 | VBZ | denotes | results |
T393 | 52-56 | IN | denotes | from |
T394 | 57-74 | NN | denotes | phosphodiesterase |
T395 | 75-85 | NN | denotes | inhibition |
T396 | 86-93 | VBZ | denotes | affects |
T397 | 94-105 | JJ | denotes | cytoplasmic |
T398 | 106-109 | CC | denotes | and |
T399 | 110-117 | JJ | denotes | nuclear |
T400 | 118-124 | NNS | denotes | events |
T401 | 124-125 | , | denotes | , |
T402 | 126-135 | VBG | denotes | resulting |
T403 | 136-138 | IN | denotes | in |
T404 | 139-142 | DT | denotes | the |
T405 | 143-154 | NN | denotes | attenuation |
T406 | 155-157 | IN | denotes | of |
T407 | 158-163 | NNP | denotes | NF-κB |
T408 | 164-167 | CC | denotes | and |
T409 | 168-171 | DT | denotes | the |
T410 | 172-182 | NN | denotes | activation |
T411 | 183-185 | IN | denotes | of |
T412 | 186-190 | NNP | denotes | CREB |
T413 | 191-206 | JJ | denotes | transcriptional |
T414 | 207-210 | NNP | denotes | DNA |
T415 | 211-218 | JJ | denotes | binding |
T416 | 219-226 | IN | denotes | through |
T417 | 227-235 | NNS | denotes | pathways |
T418 | 236-240 | WDT | denotes | that |
T419 | 241-244 | VBP | denotes | are |
T420 | 245-254 | RB | denotes | partially |
T421 | 255-262 | NNP | denotes | Protein |
T422 | 263-269 | NN | denotes | kinase |
T423 | 270-283 | NN | denotes | A-independent |
T424 | 283-284 | . | denotes | . |
R283 | T385 | T396 | nsubj | DISCUSSION,affects |
R284 | T386 | T388 | det | The,level |
R285 | T387 | T388 | amod | increased,level |
R286 | T388 | T396 | nsubj | level,affects |
R287 | T389 | T388 | prep | of,level |
R288 | T390 | T389 | pobj | cAMP,of |
R289 | T391 | T392 | nsubj | that,results |
R290 | T392 | T388 | relcl | results,level |
R291 | T393 | T392 | prep | from,results |
R292 | T394 | T395 | amod | phosphodiesterase,inhibition |
R293 | T395 | T393 | pobj | inhibition,from |
R294 | T396 | T396 | ROOT | affects,affects |
R295 | T397 | T400 | amod | cytoplasmic,events |
R296 | T398 | T397 | cc | and,cytoplasmic |
R297 | T399 | T397 | conj | nuclear,cytoplasmic |
R298 | T400 | T396 | dobj | events,affects |
R299 | T401 | T396 | punct | ",",affects |
R300 | T402 | T396 | advcl | resulting,affects |
R301 | T403 | T402 | prep | in,resulting |
R302 | T404 | T405 | det | the,attenuation |
R303 | T405 | T403 | pobj | attenuation,in |
R304 | T406 | T405 | prep | of,attenuation |
R305 | T407 | T406 | pobj | NF-κB,of |
R306 | T408 | T405 | cc | and,attenuation |
R307 | T409 | T410 | det | the,activation |
R308 | T410 | T405 | conj | activation,attenuation |
R309 | T411 | T410 | prep | of,activation |
R310 | T412 | T414 | compound | CREB,DNA |
R311 | T413 | T414 | compound | transcriptional,DNA |
R312 | T414 | T411 | pobj | DNA,of |
R313 | T415 | T410 | amod | binding,activation |
R314 | T416 | T415 | prep | through,binding |
R315 | T417 | T416 | pobj | pathways,through |
R316 | T418 | T419 | nsubj | that,are |
R317 | T419 | T417 | relcl | are,pathways |
R318 | T420 | T419 | advmod | partially,are |
R319 | T421 | T423 | compound | Protein,A-independent |
R320 | T422 | T423 | compound | kinase,A-independent |
R321 | T423 | T419 | attr | A-independent,are |
R322 | T424 | T396 | punct | .,affects |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T841 | 57-74 | http://purl.obolibrary.org/obo/GO_0008081 | denotes | phosphodiesterase |
T847 | 191-206 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcriptional |
T850 | 172-190 | http://purl.obolibrary.org/obo/GO_0032793 | denotes | activation of CREB |
T863 | 158-182 | http://purl.obolibrary.org/obo/GO_0051092 | denotes | NF-κB and the activation |
GO-MF
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T868 | 57-74 | http://purl.obolibrary.org/obo/GO_0008081 | denotes | phosphodiesterase |
T874 | 211-218 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
T879 | 207-218 | http://purl.obolibrary.org/obo/GO_0003677 | denotes | DNA binding |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T126 | 0-10 | Sentence | denotes | DISCUSSION |
T127 | 11-284 | Sentence | denotes | The increased level of cAMP that results from phosphodiesterase inhibition affects cytoplasmic and nuclear events, resulting in the attenuation of NF-κB and the activation of CREB transcriptional DNA binding through pathways that are partially Protein kinase A-independent. |
T18 | 0-10 | Sentence | denotes | DISCUSSION |
T19 | 11-284 | Sentence | denotes | The increased level of cAMP that results from phosphodiesterase inhibition affects cytoplasmic and nuclear events, resulting in the attenuation of NF-κB and the activation of CREB transcriptional DNA binding through pathways that are partially Protein kinase A-independent. |
bionlp-st-ge-2016-reference-tees
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T967 | 158-163 | Protein | denotes | NF-κB |
T968 | 186-190 | Protein | denotes | CREB |
T969 | 211-218 | Binding | denotes | binding |
T970 | 172-182 | Positive_regulation | denotes | activation |
R695 | T967 | T969 | themeOf | NF-κB,binding |
R696 | T969 | T970 | themeOf | binding,activation |
bionlp-st-ge-2016-uniprot
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T798 | 186-190 | P16220 | denotes | CREB |
T799 | 186-190 | P18848 | denotes | CREB |
T800 | 186-190 | Q02930 | denotes | CREB |
T801 | 186-190 | P15336 | denotes | CREB |
T802 | 186-190 | Q8TEY5 | denotes | CREB |
T803 | 186-190 | O43889 | denotes | CREB |