PMC:2664230 / 12589-12807 JSONTXT

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    bionlp-st-ge-2016-reference

    {"project":"bionlp-st-ge-2016-reference","denotations":[{"id":"T5627","span":{"begin":31,"end":36},"obj":"Protein"},{"id":"T5628","span":{"begin":37,"end":47},"obj":"Gene_expression"},{"id":"T5629","span":{"begin":77,"end":88},"obj":"Regulation"},{"id":"T5630","span":{"begin":96,"end":107},"obj":"Negative_regulation"},{"id":"T5631","span":{"begin":115,"end":122},"obj":"Positive_regulation"},{"id":"T5632","span":{"begin":123,"end":128},"obj":"Protein"},{"id":"T5633","span":{"begin":129,"end":139},"obj":"Gene_expression"},{"id":"T5626","span":{"begin":16,"end":20},"obj":"Regulation"}],"relations":[{"id":"R4670","pred":"themeOf","subj":"T5627","obj":"T5628"},{"id":"R4671","pred":"themeOf","subj":"T5628","obj":"T5626"},{"id":"R4672","pred":"themeOf","subj":"T5630","obj":"T5629"},{"id":"R4673","pred":"themeOf","subj":"T5631","obj":"T5630"},{"id":"R4674","pred":"themeOf","subj":"T5632","obj":"T5633"},{"id":"R4675","pred":"themeOf","subj":"T5633","obj":"T5631"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"To evaluate the role of PKA on TNF-α production in mononuclear cells and its involvement in the attenuation of LPS-induced TNF-α production observed following PTX treatment, H89, a specific PKA inhibitor, was utilized."}

    pmc-enju-pas

    {"project":"pmc-enju-pas","denotations":[{"id":"T5808","span":{"begin":0,"end":2},"obj":"TO"},{"id":"T5809","span":{"begin":3,"end":11},"obj":"VB"},{"id":"T5810","span":{"begin":12,"end":15},"obj":"DT"},{"id":"T5811","span":{"begin":16,"end":20},"obj":"NN"},{"id":"T5812","span":{"begin":21,"end":23},"obj":"IN"},{"id":"T5813","span":{"begin":24,"end":27},"obj":"NN"},{"id":"T5814","span":{"begin":28,"end":30},"obj":"IN"},{"id":"T5815","span":{"begin":31,"end":36},"obj":"NN"},{"id":"T5816","span":{"begin":37,"end":47},"obj":"NN"},{"id":"T5817","span":{"begin":48,"end":50},"obj":"IN"},{"id":"T5818","span":{"begin":51,"end":62},"obj":"JJ"},{"id":"T5819","span":{"begin":63,"end":68},"obj":"NN"},{"id":"T5820","span":{"begin":69,"end":72},"obj":"CC"},{"id":"T5821","span":{"begin":73,"end":76},"obj":"PRP-DOLLAR-"},{"id":"T5822","span":{"begin":77,"end":88},"obj":"NN"},{"id":"T5823","span":{"begin":89,"end":91},"obj":"IN"},{"id":"T5824","span":{"begin":92,"end":95},"obj":"DT"},{"id":"T5825","span":{"begin":96,"end":107},"obj":"NN"},{"id":"T5826","span":{"begin":108,"end":110},"obj":"IN"},{"id":"T5827","span":{"begin":111,"end":122},"obj":"JJ"},{"id":"T5828","span":{"begin":123,"end":128},"obj":"NN"},{"id":"T5829","span":{"begin":129,"end":139},"obj":"NN"},{"id":"T5830","span":{"begin":140,"end":148},"obj":"VB"},{"id":"T5831","span":{"begin":149,"end":158},"obj":"VB"},{"id":"T5832","span":{"begin":159,"end":162},"obj":"NN"},{"id":"T5833","span":{"begin":163,"end":172},"obj":"NN"},{"id":"T5834","span":{"begin":172,"end":173},"obj":"-COMMA-"},{"id":"T5835","span":{"begin":174,"end":177},"obj":"NN"},{"id":"T5836","span":{"begin":177,"end":178},"obj":"-COMMA-"},{"id":"T5837","span":{"begin":179,"end":180},"obj":"DT"},{"id":"T5838","span":{"begin":181,"end":189},"obj":"JJ"},{"id":"T5839","span":{"begin":190,"end":193},"obj":"NN"},{"id":"T5840","span":{"begin":194,"end":203},"obj":"NN"},{"id":"T5841","span":{"begin":203,"end":204},"obj":"-COMMA-"},{"id":"T5842","span":{"begin":205,"end":208},"obj":"VB"},{"id":"T5843","span":{"begin":209,"end":217},"obj":"VB"}],"relations":[{"id":"R4839","pred":"arg1Of","subj":"T5809","obj":"T5808"},{"id":"R4840","pred":"arg1Of","subj":"T5809","obj":"T5842"},{"id":"R4841","pred":"arg2Of","subj":"T5809","obj":"T5843"},{"id":"R4842","pred":"arg1Of","subj":"T5811","obj":"T5810"},{"id":"R4843","pred":"arg1Of","subj":"T5811","obj":"T5812"},{"id":"R4844","pred":"arg1Of","subj":"T5811","obj":"T5814"},{"id":"R4845","pred":"arg1Of","subj":"T5811","obj":"T5817"},{"id":"R4846","pred":"arg1Of","subj":"T5811","obj":"T5820"},{"id":"R4847","pred":"arg2Of","subj":"T5813","obj":"T5812"},{"id":"R4848","pred":"arg2Of","subj":"T5816","obj":"T5814"},{"id":"R4849","pred":"arg1Of","subj":"T5816","obj":"T5815"},{"id":"R4850","pred":"arg2Of","subj":"T5819","obj":"T5817"},{"id":"R4851","pred":"arg1Of","subj":"T5819","obj":"T5818"},{"id":"R4852","pred":"arg2Of","subj":"T5820","obj":"T5809"},{"id":"R4853","pred":"arg2Of","subj":"T5822","obj":"T5820"},{"id":"R4854","pred":"arg1Of","subj":"T5822","obj":"T5821"},{"id":"R4855","pred":"arg1Of","subj":"T5822","obj":"T5823"},{"id":"R4856","pred":"arg2Of","subj":"T5825","obj":"T5823"},{"id":"R4857","pred":"arg1Of","subj":"T5825","obj":"T5824"},{"id":"R4858","pred":"arg1Of","subj":"T5825","obj":"T5826"},{"id":"R4859","pred":"arg2Of","subj":"T5829","obj":"T5826"},{"id":"R4860","pred":"arg1Of","subj":"T5829","obj":"T5827"},{"id":"R4861","pred":"arg1Of","subj":"T5829","obj":"T5828"},{"id":"R4862","pred":"arg2Of","subj":"T5829","obj":"T5830"},{"id":"R4863","pred":"arg1Of","subj":"T5830","obj":"T5831"},{"id":"R4864","pred":"arg2Of","subj":"T5833","obj":"T5831"},{"id":"R4865","pred":"arg1Of","subj":"T5833","obj":"T5832"},{"id":"R4866","pred":"arg1Of","subj":"T5833","obj":"T5834"},{"id":"R4867","pred":"arg1Of","subj":"T5833","obj":"T5836"},{"id":"R4868","pred":"arg2Of","subj":"T5835","obj":"T5834"},{"id":"R4869","pred":"arg2Of","subj":"T5840","obj":"T5836"},{"id":"R4870","pred":"arg1Of","subj":"T5840","obj":"T5837"},{"id":"R4871","pred":"arg1Of","subj":"T5840","obj":"T5838"},{"id":"R4872","pred":"arg1Of","subj":"T5840","obj":"T5839"},{"id":"R4873","pred":"arg1Of","subj":"T5843","obj":"T5841"},{"id":"R4874","pred":"arg2Of","subj":"T5843","obj":"T5842"}],"namespaces":[{"prefix":"_base","uri":"http://kmcs.nii.ac.jp/enju/"}],"text":"To evaluate the role of PKA on TNF-α production in mononuclear cells and its involvement in the attenuation of LPS-induced TNF-α production observed following PTX treatment, H89, a specific PKA inhibitor, was utilized."}

    bionlp-st-ge-2016-spacy-parsed

    {"project":"bionlp-st-ge-2016-spacy-parsed","denotations":[{"id":"T5659","span":{"begin":0,"end":2},"obj":"TO"},{"id":"T5660","span":{"begin":3,"end":11},"obj":"VB"},{"id":"T5661","span":{"begin":12,"end":15},"obj":"DT"},{"id":"T5662","span":{"begin":16,"end":20},"obj":"NN"},{"id":"T5663","span":{"begin":21,"end":23},"obj":"IN"},{"id":"T5664","span":{"begin":24,"end":27},"obj":"NNP"},{"id":"T5665","span":{"begin":28,"end":30},"obj":"IN"},{"id":"T5666","span":{"begin":31,"end":36},"obj":"JJ"},{"id":"T5667","span":{"begin":37,"end":47},"obj":"NN"},{"id":"T5668","span":{"begin":48,"end":50},"obj":"IN"},{"id":"T5669","span":{"begin":51,"end":62},"obj":"NN"},{"id":"T5670","span":{"begin":63,"end":68},"obj":"NNS"},{"id":"T5671","span":{"begin":69,"end":72},"obj":"CC"},{"id":"T5672","span":{"begin":73,"end":76},"obj":"PRP$"},{"id":"T5673","span":{"begin":77,"end":88},"obj":"NN"},{"id":"T5674","span":{"begin":89,"end":91},"obj":"IN"},{"id":"T5675","span":{"begin":92,"end":95},"obj":"DT"},{"id":"T5676","span":{"begin":96,"end":107},"obj":"NN"},{"id":"T5677","span":{"begin":108,"end":110},"obj":"IN"},{"id":"T5678","span":{"begin":111,"end":122},"obj":"JJ"},{"id":"T5679","span":{"begin":123,"end":128},"obj":"JJ"},{"id":"T5680","span":{"begin":129,"end":139},"obj":"NN"},{"id":"T5681","span":{"begin":140,"end":148},"obj":"VBD"},{"id":"T5682","span":{"begin":149,"end":158},"obj":"VBG"},{"id":"T5683","span":{"begin":159,"end":162},"obj":"NNP"},{"id":"T5684","span":{"begin":163,"end":172},"obj":"NN"},{"id":"T5685","span":{"begin":172,"end":173},"obj":","},{"id":"T5686","span":{"begin":174,"end":177},"obj":"NNP"},{"id":"T5687","span":{"begin":177,"end":178},"obj":","},{"id":"T5688","span":{"begin":179,"end":180},"obj":"DT"},{"id":"T5689","span":{"begin":181,"end":189},"obj":"JJ"},{"id":"T5690","span":{"begin":190,"end":193},"obj":"NNP"},{"id":"T5691","span":{"begin":194,"end":203},"obj":"NN"},{"id":"T5692","span":{"begin":203,"end":204},"obj":","},{"id":"T5693","span":{"begin":205,"end":208},"obj":"VBD"},{"id":"T5694","span":{"begin":209,"end":217},"obj":"VBN"},{"id":"T5695","span":{"begin":217,"end":218},"obj":"."}],"relations":[{"id":"R4691","pred":"aux","subj":"T5659","obj":"T5660"},{"id":"R4693","pred":"det","subj":"T5661","obj":"T5662"},{"id":"R4694","pred":"dobj","subj":"T5662","obj":"T5660"},{"id":"R4695","pred":"prep","subj":"T5663","obj":"T5662"},{"id":"R4696","pred":"pobj","subj":"T5664","obj":"T5663"},{"id":"R4697","pred":"prep","subj":"T5665","obj":"T5662"},{"id":"R4698","pred":"amod","subj":"T5666","obj":"T5667"},{"id":"R4699","pred":"pobj","subj":"T5667","obj":"T5665"},{"id":"R4700","pred":"prep","subj":"T5668","obj":"T5667"},{"id":"R4701","pred":"amod","subj":"T5669","obj":"T5670"},{"id":"R4702","pred":"pobj","subj":"T5670","obj":"T5668"},{"id":"R4703","pred":"cc","subj":"T5671","obj":"T5670"},{"id":"R4704","pred":"poss","subj":"T5672","obj":"T5673"},{"id":"R4705","pred":"conj","subj":"T5673","obj":"T5662"},{"id":"R4706","pred":"prep","subj":"T5674","obj":"T5673"},{"id":"R4707","pred":"det","subj":"T5675","obj":"T5676"},{"id":"R4708","pred":"pobj","subj":"T5676","obj":"T5674"},{"id":"R4709","pred":"prep","subj":"T5677","obj":"T5676"},{"id":"R4710","pred":"amod","subj":"T5678","obj":"T5680"},{"id":"R4711","pred":"compound","subj":"T5679","obj":"T5680"},{"id":"R4712","pred":"pobj","subj":"T5680","obj":"T5677"},{"id":"R4713","pred":"ccomp","subj":"T5681","obj":"T5694"},{"id":"R4714","pred":"prep","subj":"T5682","obj":"T5681"},{"id":"R4715","pred":"compound","subj":"T5683","obj":"T5684"},{"id":"R4716","pred":"pobj","subj":"T5684","obj":"T5682"},{"id":"R4717","pred":"punct","subj":"T5685","obj":"T5684"},{"id":"R4718","pred":"nsubjpass","subj":"T5686","obj":"T5694"},{"id":"R4719","pred":"punct","subj":"T5687","obj":"T5686"},{"id":"R4720","pred":"det","subj":"T5688","obj":"T5691"},{"id":"R4721","pred":"amod","subj":"T5689","obj":"T5691"},{"id":"R4722","pred":"compound","subj":"T5690","obj":"T5691"},{"id":"R4723","pred":"appos","subj":"T5691","obj":"T5686"},{"id":"R4724","pred":"punct","subj":"T5692","obj":"T5694"},{"id":"R4725","pred":"auxpass","subj":"T5693","obj":"T5694"},{"id":"R4726","pred":"ROOT","subj":"T5694","obj":"T5694"},{"id":"R4727","pred":"punct","subj":"T5695","obj":"T5694"}],"text":"To evaluate the role of PKA on TNF-α production in mononuclear cells and its involvement in the attenuation of LPS-induced TNF-α production observed following PTX treatment, H89, a specific PKA inhibitor, was utilized."}

    GO-BP

    {"project":"GO-BP","denotations":[{"id":"T5961","span":{"begin":24,"end":27},"obj":"http://purl.obolibrary.org/obo/GO_0004691"},{"id":"T5962","span":{"begin":190,"end":193},"obj":"http://purl.obolibrary.org/obo/GO_0004691"},{"id":"T5966","span":{"begin":31,"end":47},"obj":"http://purl.obolibrary.org/obo/GO_0032680"},{"id":"T5967","span":{"begin":123,"end":139},"obj":"http://purl.obolibrary.org/obo/GO_0032680"},{"id":"T5969","span":{"begin":31,"end":47},"obj":"http://purl.obolibrary.org/obo/GO_0032640"},{"id":"T5970","span":{"begin":123,"end":139},"obj":"http://purl.obolibrary.org/obo/GO_0032640"}],"text":"To evaluate the role of PKA on TNF-α production in mononuclear cells and its involvement in the attenuation of LPS-induced TNF-α production observed following PTX treatment, H89, a specific PKA inhibitor, was utilized."}

    GO-MF

    {"project":"GO-MF","denotations":[{"id":"T5972","span":{"begin":24,"end":27},"obj":"http://purl.obolibrary.org/obo/GO_0004691"},{"id":"T5973","span":{"begin":190,"end":193},"obj":"http://purl.obolibrary.org/obo/GO_0004691"}],"text":"To evaluate the role of PKA on TNF-α production in mononuclear cells and its involvement in the attenuation of LPS-induced TNF-α production observed following PTX treatment, H89, a specific PKA inhibitor, was utilized."}

    GO-CC

    {"project":"GO-CC","denotations":[{"id":"T5978","span":{"begin":190,"end":193},"obj":"http://purl.obolibrary.org/obo/GO_0005952"},{"id":"T5982","span":{"begin":63,"end":68},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T5977","span":{"begin":24,"end":27},"obj":"http://purl.obolibrary.org/obo/GO_0005952"}],"text":"To evaluate the role of PKA on TNF-α production in mononuclear cells and its involvement in the attenuation of LPS-induced TNF-α production observed following PTX treatment, H89, a specific PKA inhibitor, was utilized."}

    sentences

    {"project":"sentences","denotations":[{"id":"T5644","span":{"begin":0,"end":218},"obj":"Sentence"},{"id":"T94","span":{"begin":0,"end":218},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"To evaluate the role of PKA on TNF-α production in mononuclear cells and its involvement in the attenuation of LPS-induced TNF-α production observed following PTX treatment, H89, a specific PKA inhibitor, was utilized."}

    events-check-again

    {"project":"events-check-again","denotations":[{"id":"T6044","span":{"begin":16,"end":20},"obj":"Regulation"},{"id":"T6045","span":{"begin":31,"end":36},"obj":"Protein"},{"id":"T6046","span":{"begin":37,"end":47},"obj":"Gene_expression"},{"id":"T6047","span":{"begin":77,"end":88},"obj":"Regulation"},{"id":"T6048","span":{"begin":96,"end":107},"obj":"Negative_regulation"},{"id":"T6049","span":{"begin":115,"end":122},"obj":"Positive_regulation"},{"id":"T6050","span":{"begin":123,"end":128},"obj":"Protein"},{"id":"T6051","span":{"begin":129,"end":139},"obj":"Gene_expression"}],"relations":[{"id":"R5020","pred":"themeOf","subj":"T6045","obj":"T6046"},{"id":"R5021","pred":"themeOf","subj":"T6046","obj":"T6044"},{"id":"R5022","pred":"themeOf","subj":"T6048","obj":"T6047"},{"id":"R5023","pred":"themeOf","subj":"T6049","obj":"T6048"},{"id":"R5024","pred":"themeOf","subj":"T6050","obj":"T6051"},{"id":"R5025","pred":"themeOf","subj":"T6051","obj":"T6049"}],"text":"To evaluate the role of PKA on TNF-α production in mononuclear cells and its involvement in the attenuation of LPS-induced TNF-α production observed following PTX treatment, H89, a specific PKA inhibitor, was utilized."}

    bionlp-st-ge-2016-reference-tees

    {"project":"bionlp-st-ge-2016-reference-tees","denotations":[{"id":"T5989","span":{"begin":24,"end":27},"obj":"Protein"},{"id":"T5990","span":{"begin":31,"end":36},"obj":"Protein"},{"id":"T5991","span":{"begin":123,"end":128},"obj":"Protein"},{"id":"T5992","span":{"begin":190,"end":193},"obj":"Protein"},{"id":"T5993","span":{"begin":37,"end":47},"obj":"Gene_expression"},{"id":"T5994","span":{"begin":129,"end":139},"obj":"Gene_expression"},{"id":"T5995","span":{"begin":194,"end":203},"obj":"Negative_regulation"},{"id":"T5996","span":{"begin":16,"end":20},"obj":"Regulation"},{"id":"T5997","span":{"begin":96,"end":107},"obj":"Negative_regulation"},{"id":"T5998","span":{"begin":77,"end":88},"obj":"Regulation"}],"relations":[{"id":"R4984","pred":"causeOf","subj":"T5989","obj":"T5996"},{"id":"R4985","pred":"themeOf","subj":"T5990","obj":"T5993"},{"id":"R4986","pred":"themeOf","subj":"T5991","obj":"T5994"},{"id":"R4987","pred":"themeOf","subj":"T5992","obj":"T5995"},{"id":"R4988","pred":"themeOf","subj":"T5993","obj":"T5996"},{"id":"R4989","pred":"themeOf","subj":"T5994","obj":"T5997"},{"id":"R4990","pred":"themeOf","subj":"T5997","obj":"T5998"}],"text":"To evaluate the role of PKA on TNF-α production in mononuclear cells and its involvement in the attenuation of LPS-induced TNF-α production observed following PTX treatment, H89, a specific PKA inhibitor, was utilized."}

    bionlp-st-ge-2016-uniprot

    {"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T5944","span":{"begin":31,"end":34},"obj":"P01375"},{"id":"T5945","span":{"begin":31,"end":36},"obj":"P01375"},{"id":"T5946","span":{"begin":123,"end":126},"obj":"P01375"},{"id":"T5947","span":{"begin":123,"end":128},"obj":"P01375"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"To evaluate the role of PKA on TNF-α production in mononuclear cells and its involvement in the attenuation of LPS-induced TNF-α production observed following PTX treatment, H89, a specific PKA inhibitor, was utilized."}

    test2

    {"project":"test2","denotations":[{"id":"T5614","span":{"begin":16,"end":20},"obj":"Regulation"},{"id":"T5615","span":{"begin":31,"end":36},"obj":"Protein"},{"id":"T5616","span":{"begin":37,"end":47},"obj":"Gene_expression"},{"id":"T5617","span":{"begin":115,"end":122},"obj":"Positive_regulation"},{"id":"T5618","span":{"begin":123,"end":128},"obj":"Protein"},{"id":"T5619","span":{"begin":129,"end":139},"obj":"Gene_expression"},{"id":"T5620","span":{"begin":149,"end":158},"obj":"Positive_regulation"}],"relations":[{"id":"R4662","pred":"themeOf","subj":"T5615","obj":"T5616"},{"id":"R4663","pred":"themeOf","subj":"T5617","obj":"T5620"},{"id":"R4664","pred":"themeOf","subj":"T5618","obj":"T5619"},{"id":"R4665","pred":"themeOf","subj":"T5619","obj":"T5620"},{"id":"R4666","pred":"themeOf","subj":"T5619","obj":"T5617"}],"text":"To evaluate the role of PKA on TNF-α production in mononuclear cells and its involvement in the attenuation of LPS-induced TNF-α production observed following PTX treatment, H89, a specific PKA inhibitor, was utilized."}