Abbreviations Adv = adenovirus; Ang-1 = angiopoietin-1; ASV = alternative splice variants; CIA = collagen-induced arthritis; CSF = colony-stimulating factor; Fc = crystallizable fragment; FGFR = fibroblast growth factor receptor; H & E = hematoxylin and eosin; HUVEC = human umbilical vein endothelial cells; PBS = phosphate-buffered saline; PCR = polymerase chain reaction; PDGF = platelet-derived growth factor; PDGFRβ = platelet-derived growth factor receptor beta; RA = rheumatoid arthritis; RT = reverse transcriptase; RTK = receptor tyrosine kinase; Tie = tyrosine kinase with immunoglobulin and epidermal growth factor homology domains; TNF = tumor necrosis factor; VEGF = vascular endothelial growth factor; VEGFR = vascular endothelial growth factor receptor.