Fig. 2 Photomicrographs of 40 μm frozen sections stained according to our standard protocols. (a) Frontal lobe stained with H & E, showing periventricular white matter rarefaction; (b) hippocampus stained with the Campbell-Switzer silver method, showing senile plaques and neurofibrillary tangles; (c) neurofibrillary tangles stained with the Gallyas silver method; (d) neuron in the dentate gyrus granular cell layer stained immunohistochemically for phosphorylated tau protein with the AT8 antibody; (e) tufted astrocyte stained with the Gallyas method; (f) thorned astrocyte stained with the Gallyas method; (g) oligodendroglial coiled body stained with the Gallyas method