PMC:1942070 / 8417-8805
Annnotations
pmc-enju-pas
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T4099 | 0-2 | IN | denotes | As |
T4100 | 3-8 | VB | denotes | shown |
T4101 | 9-11 | IN | denotes | in |
T4102 | 12-16 | NNP | denotes | Fig. |
T4103 | 17-19 | NN | denotes | 2B |
T4104 | 19-20 | -COMMA- | denotes | , |
T4105 | 21-25 | NN | denotes | loss |
T4106 | 26-28 | IN | denotes | of |
T4107 | 29-35 | NN | denotes | PKD1/3 |
T4108 | 36-46 | NN | denotes | expression |
T4109 | 47-50 | VB | denotes | had |
T4110 | 51-53 | DT | denotes | no |
T4111 | 54-65 | JJ | denotes | significant |
T4112 | 66-72 | NN | denotes | impact |
T4113 | 73-75 | IN | denotes | on |
T4114 | 76-79 | DT | denotes | the |
T4115 | 80-88 | NN | denotes | survival |
T4116 | 89-91 | IN | denotes | of |
T4117 | 92-96 | NN | denotes | DT40 |
T4118 | 97-98 | NN | denotes | B |
T4119 | 99-104 | NN | denotes | cells |
T4120 | 105-107 | IN | denotes | in |
T4121 | 108-116 | NN | denotes | response |
T4122 | 117-119 | TO | denotes | to |
T4123 | 120-133 | JJ | denotes | mitochondrial |
T4124 | 134-140 | NN | denotes | stress |
T4125 | 141-148 | NN | denotes | stimuli |
T4126 | 149-150 | -LRB- | denotes | ( |
T4127 | 150-154 | NN | denotes | H2O2 |
T4128 | 155-157 | CC | denotes | or |
T4129 | 158-163 | NN | denotes | serum |
T4130 | 164-175 | NN | denotes | deprivation |
T4131 | 175-176 | -RRB- | denotes | ) |
T4132 | 176-177 | -COLON- | denotes | ; |
T4133 | 178-181 | NN | denotes | DNA |
T4134 | 182-190 | NN | denotes | damaging |
T4135 | 191-197 | NN | denotes | agents |
T4136 | 198-199 | -LRB- | denotes | ( |
T4137 | 199-208 | NN | denotes | etoposide |
T4138 | 209-211 | CC | denotes | or |
T4139 | 212-223 | NN | denotes | doxorubicin |
T4140 | 223-224 | -RRB- | denotes | ) |
T4141 | 224-225 | -COLON- | denotes | ; |
T4142 | 226-228 | NN | denotes | ER |
T4143 | 229-236 | NN | denotes | pathway |
T4144 | 237-243 | NN | denotes | stress |
T4145 | 244-247 | IN | denotes | due |
T4146 | 248-250 | TO | denotes | to |
T4147 | 251-258 | NN | denotes | calcium |
T4148 | 259-267 | NN | denotes | overload |
T4149 | 268-269 | -LRB- | denotes | ( |
T4150 | 269-281 | NN | denotes | thapsigargin |
T4151 | 281-282 | -RRB- | denotes | ) |
T4152 | 283-285 | CC | denotes | or |
T4153 | 286-295 | VB | denotes | following |
T4154 | 296-305 | VB | denotes | prolonged |
T4155 | 306-315 | NN | denotes | treatment |
T4156 | 316-320 | IN | denotes | with |
T4157 | 321-328 | NN | denotes | phorbol |
T4158 | 329-335 | NN | denotes | esters |
T4159 | 336-338 | CC | denotes | or |
T4160 | 339-351 | NN | denotes | Trichostatin |
T4161 | 352-353 | NN | denotes | A |
T4162 | 353-354 | -COMMA- | denotes | , |
T4163 | 355-357 | DT | denotes | an |
T4164 | 358-367 | NN | denotes | inhibitor |
T4165 | 368-370 | IN | denotes | of |
T4166 | 371-376 | NN | denotes | class |
T4167 | 377-381 | NN | denotes | I/II |
T4168 | 382-387 | NN | denotes | HDACs |
R3322 | T4100 | T4099 | arg2Of | shown,As |
R3323 | T4100 | T4101 | arg1Of | shown,in |
R3324 | T4103 | T4101 | arg2Of | 2B,in |
R3325 | T4103 | T4102 | arg1Of | 2B,Fig. |
R3326 | T4105 | T4106 | arg1Of | loss,of |
R3327 | T4105 | T4109 | arg1Of | loss,had |
R3328 | T4108 | T4106 | arg2Of | expression,of |
R3329 | T4108 | T4107 | arg1Of | expression,PKD1/3 |
R3330 | T4109 | T4099 | arg1Of | had,As |
R3331 | T4109 | T4104 | arg1Of | had,"," |
R3332 | T4109 | T4113 | arg1Of | had,on |
R3333 | T4109 | T4120 | arg1Of | had,in |
R3334 | T4109 | T4153 | arg1Of | had,following |
R3335 | T4112 | T4109 | arg2Of | impact,had |
R3336 | T4112 | T4110 | arg1Of | impact,no |
R3337 | T4112 | T4111 | arg1Of | impact,significant |
R3338 | T4115 | T4113 | arg2Of | survival,on |
R3339 | T4115 | T4114 | arg1Of | survival,the |
R3340 | T4115 | T4116 | arg1Of | survival,of |
R3341 | T4119 | T4116 | arg2Of | cells,of |
R3342 | T4119 | T4117 | arg1Of | cells,DT40 |
R3343 | T4119 | T4118 | arg1Of | cells,B |
R3344 | T4120 | T4122 | arg1Of | in,to |
R3345 | T4120 | T4152 | arg1Of | in,or |
R3346 | T4121 | T4120 | arg2Of | response,in |
R3347 | T4125 | T4123 | arg1Of | stimuli,mitochondrial |
R3348 | T4125 | T4124 | arg1Of | stimuli,stress |
R3349 | T4125 | T4126 | arg1Of | stimuli,( |
R3350 | T4125 | T4132 | arg1Of | stimuli,; |
R3351 | T4127 | T4128 | arg1Of | H2O2,or |
R3352 | T4128 | T4126 | arg2Of | or,( |
R3353 | T4130 | T4128 | arg2Of | deprivation,or |
R3354 | T4130 | T4129 | arg1Of | deprivation,serum |
R3355 | T4131 | T4126 | arg3Of | ),( |
R3356 | T4132 | T4141 | arg1Of | ;,; |
R3357 | T4135 | T4132 | arg2Of | agents,; |
R3358 | T4135 | T4133 | arg1Of | agents,DNA |
R3359 | T4135 | T4134 | arg1Of | agents,damaging |
R3360 | T4135 | T4136 | arg1Of | agents,( |
R3361 | T4137 | T4138 | arg1Of | etoposide,or |
R3362 | T4138 | T4136 | arg2Of | or,( |
R3363 | T4139 | T4138 | arg2Of | doxorubicin,or |
R3364 | T4140 | T4136 | arg3Of | ),( |
R3365 | T4141 | T4120 | arg3Of | ;,in |
R3366 | T4144 | T4141 | arg2Of | stress,; |
R3367 | T4144 | T4142 | arg1Of | stress,ER |
R3368 | T4144 | T4143 | arg1Of | stress,pathway |
R3369 | T4144 | T4145 | arg1Of | stress,due |
R3370 | T4145 | T4146 | arg1Of | due,to |
R3371 | T4148 | T4145 | arg2Of | overload,due |
R3372 | T4148 | T4147 | arg1Of | overload,calcium |
R3373 | T4148 | T4149 | arg1Of | overload,( |
R3374 | T4150 | T4149 | arg2Of | thapsigargin,( |
R3375 | T4151 | T4149 | arg3Of | ),( |
R3376 | T4153 | T4152 | arg2Of | following,or |
R3377 | T4155 | T4153 | arg2Of | treatment,following |
R3378 | T4155 | T4154 | arg2Of | treatment,prolonged |
R3379 | T4155 | T4156 | arg1Of | treatment,with |
R3380 | T4158 | T4157 | arg1Of | esters,phorbol |
R3381 | T4158 | T4159 | arg1Of | esters,or |
R3382 | T4159 | T4156 | arg2Of | or,with |
R3383 | T4159 | T4162 | arg1Of | or,"," |
R3384 | T4161 | T4159 | arg2Of | A,or |
R3385 | T4161 | T4160 | arg1Of | A,Trichostatin |
R3386 | T4164 | T4162 | arg2Of | inhibitor,"," |
R3387 | T4164 | T4163 | arg1Of | inhibitor,an |
R3388 | T4164 | T4165 | arg1Of | inhibitor,of |
R3389 | T4168 | T4165 | arg2Of | HDACs,of |
R3390 | T4168 | T4166 | arg1Of | HDACs,class |
R3391 | T4168 | T4167 | arg1Of | HDACs,I/II |
bionlp-st-ge-2016-spacy-parsed
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T4516 | 0-2 | IN | denotes | As |
T4517 | 3-8 | VBN | denotes | shown |
T4518 | 9-11 | IN | denotes | in |
T4519 | 12-16 | NNP | denotes | Fig. |
T4520 | 17-19 | NNP | denotes | 2B |
T4521 | 19-20 | , | denotes | , |
T4522 | 21-25 | NN | denotes | loss |
T4523 | 26-28 | IN | denotes | of |
T4524 | 29-35 | CD | denotes | PKD1/3 |
T4525 | 36-46 | NN | denotes | expression |
T4526 | 47-50 | VBD | denotes | had |
T4527 | 51-53 | DT | denotes | no |
T4528 | 54-65 | JJ | denotes | significant |
T4529 | 66-72 | NN | denotes | impact |
T4530 | 73-75 | IN | denotes | on |
T4531 | 76-79 | DT | denotes | the |
T4532 | 80-88 | NN | denotes | survival |
T4533 | 89-91 | IN | denotes | of |
T4534 | 92-96 | NNP | denotes | DT40 |
T4535 | 97-98 | NNP | denotes | B |
T4536 | 99-104 | NNS | denotes | cells |
T4537 | 105-107 | IN | denotes | in |
T4538 | 108-116 | NN | denotes | response |
T4539 | 117-119 | TO | denotes | to |
T4540 | 120-133 | JJ | denotes | mitochondrial |
T4541 | 134-140 | NN | denotes | stress |
T4542 | 141-148 | NNS | denotes | stimuli |
T4543 | 149-150 | -LRB- | denotes | ( |
T4544 | 150-154 | CD | denotes | H2O2 |
T4545 | 155-157 | CC | denotes | or |
T4546 | 158-163 | NN | denotes | serum |
T4547 | 164-175 | NN | denotes | deprivation |
T4548 | 175-176 | -RRB- | denotes | ) |
T4549 | 176-177 | : | denotes | ; |
T4550 | 178-181 | NNP | denotes | DNA |
T4551 | 182-190 | VBG | denotes | damaging |
T4552 | 191-197 | NNS | denotes | agents |
T4553 | 198-199 | -LRB- | denotes | ( |
T4554 | 199-208 | NN | denotes | etoposide |
T4555 | 209-211 | CC | denotes | or |
T4556 | 212-223 | NN | denotes | doxorubicin |
T4557 | 223-224 | -RRB- | denotes | ) |
T4558 | 224-225 | : | denotes | ; |
T4559 | 226-228 | NNP | denotes | ER |
T4560 | 229-236 | NN | denotes | pathway |
T4561 | 237-243 | NN | denotes | stress |
T4562 | 244-247 | JJ | denotes | due |
T4563 | 248-250 | TO | denotes | to |
T4564 | 251-258 | NN | denotes | calcium |
T4565 | 259-267 | NN | denotes | overload |
T4566 | 268-269 | -LRB- | denotes | ( |
T4567 | 269-281 | NN | denotes | thapsigargin |
T4568 | 281-282 | -RRB- | denotes | ) |
T4569 | 283-285 | CC | denotes | or |
T4570 | 286-295 | VBG | denotes | following |
T4571 | 296-305 | JJ | denotes | prolonged |
T4572 | 306-315 | NN | denotes | treatment |
T4573 | 316-320 | IN | denotes | with |
T4574 | 321-328 | NN | denotes | phorbol |
T4575 | 329-335 | NNS | denotes | esters |
T4576 | 336-338 | CC | denotes | or |
T4577 | 339-351 | NNP | denotes | Trichostatin |
T4578 | 352-353 | NNP | denotes | A |
T4579 | 353-354 | , | denotes | , |
T4580 | 355-357 | DT | denotes | an |
T4581 | 358-367 | NN | denotes | inhibitor |
T4582 | 368-370 | IN | denotes | of |
T4583 | 371-376 | NN | denotes | class |
T4584 | 377-381 | NNP | denotes | I/II |
T4585 | 382-387 | NNP | denotes | HDACs |
T4586 | 387-388 | . | denotes | . |
R3715 | T4516 | T4517 | mark | As,shown |
R3716 | T4517 | T4526 | advcl | shown,had |
R3717 | T4518 | T4517 | prep | in,shown |
R3718 | T4519 | T4520 | compound | Fig.,2B |
R3719 | T4520 | T4518 | pobj | 2B,in |
R3720 | T4521 | T4520 | punct | ",",2B |
R3721 | T4522 | T4520 | appos | loss,2B |
R3722 | T4523 | T4522 | prep | of,loss |
R3723 | T4524 | T4525 | nummod | PKD1/3,expression |
R3724 | T4525 | T4523 | pobj | expression,of |
R3725 | T4526 | T4526 | ROOT | had,had |
R3726 | T4527 | T4529 | det | no,impact |
R3727 | T4528 | T4529 | amod | significant,impact |
R3728 | T4529 | T4526 | dobj | impact,had |
R3729 | T4530 | T4529 | prep | on,impact |
R3730 | T4531 | T4532 | det | the,survival |
R3731 | T4532 | T4530 | pobj | survival,on |
R3732 | T4533 | T4532 | prep | of,survival |
R3733 | T4534 | T4535 | compound | DT40,B |
R3734 | T4535 | T4536 | compound | B,cells |
R3735 | T4536 | T4533 | pobj | cells,of |
R3736 | T4537 | T4526 | prep | in,had |
R3737 | T4538 | T4537 | pobj | response,in |
R3738 | T4539 | T4538 | prep | to,response |
R3739 | T4540 | T4542 | amod | mitochondrial,stimuli |
R3740 | T4541 | T4542 | compound | stress,stimuli |
R3741 | T4542 | T4539 | pobj | stimuli,to |
R3742 | T4543 | T4542 | punct | (,stimuli |
R3743 | T4544 | T4542 | appos | H2O2,stimuli |
R3744 | T4545 | T4544 | cc | or,H2O2 |
R3745 | T4546 | T4547 | compound | serum,deprivation |
R3746 | T4547 | T4544 | conj | deprivation,H2O2 |
R3747 | T4548 | T4542 | punct | ),stimuli |
R3748 | T4549 | T4542 | punct | ;,stimuli |
R3749 | T4550 | T4552 | amod | DNA,agents |
R3750 | T4551 | T4552 | amod | damaging,agents |
R3751 | T4552 | T4542 | conj | agents,stimuli |
R3752 | T4553 | T4552 | punct | (,agents |
R3753 | T4554 | T4552 | appos | etoposide,agents |
R3754 | T4555 | T4554 | cc | or,etoposide |
R3755 | T4556 | T4554 | conj | doxorubicin,etoposide |
R3756 | T4557 | T4552 | punct | ),agents |
R3757 | T4558 | T4526 | punct | ;,had |
R3758 | T4559 | T4561 | compound | ER,stress |
R3759 | T4560 | T4561 | compound | pathway,stress |
R3760 | T4561 | T4570 | nsubj | stress,following |
R3761 | T4562 | T4561 | amod | due,stress |
R3762 | T4563 | T4562 | pcomp | to,due |
R3763 | T4564 | T4565 | compound | calcium,overload |
R3764 | T4565 | T4562 | pobj | overload,due |
R3765 | T4566 | T4567 | punct | (,thapsigargin |
R3766 | T4567 | T4565 | appos | thapsigargin,overload |
R3767 | T4568 | T4567 | punct | ),thapsigargin |
R3768 | T4569 | T4565 | cc | or,overload |
R3769 | T4570 | T4526 | advcl | following,had |
R3770 | T4571 | T4572 | amod | prolonged,treatment |
R3771 | T4572 | T4570 | dobj | treatment,following |
R3772 | T4573 | T4572 | prep | with,treatment |
R3773 | T4574 | T4575 | compound | phorbol,esters |
R3774 | T4575 | T4573 | pobj | esters,with |
R3775 | T4576 | T4575 | cc | or,esters |
R3776 | T4577 | T4578 | compound | Trichostatin,A |
R3777 | T4578 | T4575 | conj | A,esters |
R3778 | T4579 | T4578 | punct | ",",A |
R3779 | T4580 | T4581 | det | an,inhibitor |
R3780 | T4581 | T4578 | appos | inhibitor,A |
R3781 | T4582 | T4581 | prep | of,inhibitor |
R3782 | T4583 | T4585 | compound | class,HDACs |
R3783 | T4584 | T4585 | compound | I/II,HDACs |
R3784 | T4585 | T4582 | pobj | HDACs,of |
R3785 | T4586 | T4526 | punct | .,had |
UBERON-AE
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3782 | 158-163 | http://purl.obolibrary.org/obo/UBERON_0001977 | denotes | serum |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3835 | 108-140 | http://purl.obolibrary.org/obo/GO_1990046 | denotes | response to mitochondrial stress |
GO-CC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T4623 | 99-104 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T4625 | 226-228 | http://purl.obolibrary.org/obo/GO_0005783 | denotes | ER |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3818 | 0-388 | Sentence | denotes | As shown in Fig. 2B, loss of PKD1/3 expression had no significant impact on the survival of DT40 B cells in response to mitochondrial stress stimuli (H2O2 or serum deprivation); DNA damaging agents (etoposide or doxorubicin); ER pathway stress due to calcium overload (thapsigargin) or following prolonged treatment with phorbol esters or Trichostatin A, an inhibitor of class I/II HDACs. |
T60 | 0-388 | Sentence | denotes | As shown in Fig. 2B, loss of PKD1/3 expression had no significant impact on the survival of DT40 B cells in response to mitochondrial stress stimuli (H2O2 or serum deprivation); DNA damaging agents (etoposide or doxorubicin); ER pathway stress due to calcium overload (thapsigargin) or following prolonged treatment with phorbol esters or Trichostatin A, an inhibitor of class I/II HDACs. |
events-check-again
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T4770 | 21-25 | Negative_regulation | denotes | loss |
T4771 | 21-25 | Negative_regulation | denotes | loss |
T4772 | 29-33 | Protein | denotes | PKD1 |
T4773 | 34-35 | Protein | denotes | 3 |
T4774 | 36-46 | Gene_expression | denotes | expression |
T4775 | 36-46 | Gene_expression | denotes | expression |
R3845 | T4772 | T4774 | themeOf | PKD1,expression |
R3846 | T4773 | T4775 | themeOf | 3,expression |
R3847 | T4774 | T4771 | themeOf | expression,loss |
R3848 | T4775 | T4770 | themeOf | expression,loss |
bionlp-st-ge-2016-reference-tees
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T4806 | 12-15 | Protein | denotes | Fig |
T4807 | 29-33 | Protein | denotes | PKD1 |
T4808 | 34-35 | Protein | denotes | 3 |
T4809 | 92-98 | Protein | denotes | DT40 B |
T4810 | 377-387 | Protein | denotes | I/II HDACs |
T4811 | 36-46 | Gene_expression | denotes | expression |
T4812 | 36-46 | Gene_expression | denotes | expression |
T4813 | 358-367 | Negative_regulation | denotes | inhibitor |
T4814 | 21-25 | Negative_regulation | denotes | loss |
T4815 | 21-25 | Negative_regulation | denotes | loss |
R3856 | T4807 | T4811 | themeOf | PKD1,expression |
R3857 | T4808 | T4812 | themeOf | 3,expression |
R3858 | T4810 | T4813 | themeOf | I/II HDACs,inhibitor |
R3859 | T4811 | T4814 | themeOf | expression,loss |
R3860 | T4812 | T4815 | themeOf | expression,loss |
bionlp-st-ge-2016-reference
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3802 | 21-25 | Negative_regulation | denotes | loss |
T3803 | 21-25 | Negative_regulation | denotes | loss |
T3804 | 29-33 | Protein | denotes | PKD1 |
T3805 | 34-35 | Protein | denotes | 3 |
T3806 | 36-46 | Gene_expression | denotes | expression |
T3807 | 36-46 | Gene_expression | denotes | expression |
R3052 | T3804 | T3806 | themeOf | PKD1,expression |
R3053 | T3805 | T3807 | themeOf | 3,expression |
R3054 | T3806 | T3803 | themeOf | expression,loss |
R3055 | T3807 | T3802 | themeOf | expression,loss |
bionlp-st-ge-2016-uniprot
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T4203 | 29-33 | P98161 | denotes | PKD1 |
T4204 | 226-228 | P03372 | denotes | ER |
test2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T3777 | 21-25 | Negative_regulation | denotes | loss |
T3778 | 29-33 | Protein | denotes | PKD1 |
T3779 | 34-35 | Protein | denotes | 3 |
T3780 | 36-46 | Gene_expression | denotes | expression |
T3781 | 358-367 | Negative_regulation | denotes | inhibitor |
R3047 | T3778 | T3780 | themeOf | PKD1,expression |
R3048 | T3779 | T3780 | themeOf | 3,expression |
R3049 | T3780 | T3777 | themeOf | expression,loss |