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PMC:1920263 / 23089-27540 JSONTXT

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test2

Id Subject Object Predicate Lexical cue Negation Speculation
T8709 4-7 Protein denotes A3G true
T8710 24-33 Positive_regulation denotes inducible
T8711 81-89 Protein denotes APOBEC3G
T8712 193-203 Negative_regulation denotes counteract
T8713 204-207 Protein denotes A3G
T8714 220-230 Gene_expression denotes expressing
T8715 254-257 Protein denotes Vif
T8716 263-266 Protein denotes Vif
T8717 267-274 Positive_regulation denotes induces true true
T8718 287-298 Protein_catabolism denotes degradation
T8719 302-305 Protein denotes A3G
T8720 323-331 Negative_regulation denotes inhibits
T8721 332-335 Protein denotes A3G
T8722 455-458 Protein denotes A3G
T8723 488-497 Gene_expression denotes expressed
T8724 504-507 Protein denotes Vif
T8725 521-524 Protein denotes Tat true
T8726 849-859 Protein denotes Luciferase
T8727 883-898 Transcription denotes transcriptional
T8728 915-918 Protein denotes A3G
T8729 919-927 Entity denotes promoter
T8730 950-957 Regulation denotes altered
T8731 977-980 Protein denotes Vif
T8732 982-985 Protein denotes Tat
T8733 1042-1052 Regulation denotes modulating
T8734 1053-1056 Protein denotes A3G
T8735 1057-1067 Gene_expression denotes expression
T8736 2727-2730 Protein denotes A3G
T8737 2750-2759 Positive_regulation denotes increased
T8738 2873-2883 Positive_regulation denotes upregulate
T8739 2884-2887 Protein denotes A3G
T8740 2888-2898 Gene_expression denotes expression
T8741 2991-2994 Protein denotes A3G
T8742 3172-3182 Protein denotes luciferase
T8743 3214-3223 Positive_regulation denotes increased
T8744 3318-3326 Positive_regulation denotes enhanced
T8745 3563-3566 Protein denotes A3G
T8746 3576-3584 Negative_regulation denotes deletion
T8747 3601-3606 Protein denotes IFN-α
T8748 3610-3615 Protein denotes IFN-γ
T8749 3776-3786 Protein denotes luciferase
T8750 3810-3817 Positive_regulation denotes induced
T8751 3821-3826 Protein denotes IFN-α
T8752 3882-3885 Protein denotes A3G
T8753 3886-3898 Positive_regulation denotes upregulation
T8754 4059-4068 Positive_regulation denotes induction
T8755 4076-4079 Protein denotes A3G
T8756 4080-4088 Entity denotes promoter
T8757 4119-4124 Protein denotes IFN-α
T8758 4128-4133 Protein denotes IFN-γ
T8759 4163-4168 Protein denotes IFN-γ
T8760 4224-4233 Positive_regulation denotes induction
T8761 4237-4240 Protein denotes A3G
T8762 4241-4249 Entity denotes promoter
T19312 1108-1111 Protein denotes A3G
T19313 1300-1303 Protein denotes A3G
T19314 1325-1328 Protein denotes Vif
T19315 1329-1339 Gene_expression denotes expression
T19316 1354-1357 Protein denotes Tat
T19317 1358-1368 Gene_expression denotes expression
T19318 1471-1481 Protein denotes luciferase
T19319 1497-1507 Protein denotes luciferase
T19320 1538-1549 Gene_expression denotes coexpressed
T19321 1558-1568 Protein denotes luciferase
T19322 1684-1687 Protein denotes A3G
T19323 1754-1764 Protein denotes luciferase
T19324 1872-1882 Protein denotes luciferase
T19325 1912-1922 Protein denotes luciferase
T19326 1953-1964 Gene_expression denotes coexpressed
T19327 1973-1983 Protein denotes luciferase
T19328 2134-2137 Protein denotes A3G
T19329 2170-2180 Protein denotes interferon
T19330 2260-2270 Protein denotes luciferase
T19331 2311-2321 Positive_regulation denotes stimulated
T19332 2336-2341 Protein denotes IFN-α
T19333 2345-2350 Protein denotes IFN-γ
T19334 2389-2399 Protein denotes luciferase
T19335 2429-2439 Protein denotes luciferase
T19336 2470-2481 Gene_expression denotes coexpressed
T19337 2490-2500 Protein denotes luciferase
R7155 T8713 T8712 themeOf A3G,counteract
R7156 T8714 T8712 causeOf expressing,counteract
R7157 T8715 T8714 themeOf Vif,expressing
R7158 T8716 T8720 causeOf Vif,inhibits
R7159 T8716 T8717 causeOf Vif,induces
R7160 T8718 T8717 themeOf degradation,induces
R7161 T8719 T8718 themeOf A3G,degradation
R7162 T8721 T8720 themeOf A3G,inhibits
R7163 T8724 T8723 themeOf Vif,expressed
R7164 T8725 T8723 themeOf Tat,expressed
R7165 T8727 T8730 themeOf transcriptional,altered
R7166 T8729 T8727 themeOf promoter,transcriptional
R7167 T8729 T8728 partOf promoter,A3G
R7168 T8732 T8730 causeOf Tat,altered
R7169 T8734 T8735 themeOf A3G,expression
R7170 T8735 T8733 themeOf expression,modulating
R7171 T8739 T8740 themeOf A3G,expression
R7172 T8740 T8738 themeOf expression,upregulate
R7173 T8742 T8744 themeOf luciferase,enhanced
R7174 T8743 T8744 themeOf increased,enhanced
R7175 T8751 T8750 causeOf IFN-α,induced
R7176 T8752 T8753 themeOf A3G,upregulation
R7177 T8756 T8754 themeOf promoter,induction
R7178 T8756 T8755 partOf promoter,A3G
R7179 T8762 T8760 themeOf promoter,induction
R15627 T19314 T19315 themeOf Vif,expression
R15628 T19316 T19317 themeOf Tat,expression
R15629 T19319 T19320 themeOf luciferase,coexpressed
R15630 T19321 T19320 themeOf luciferase,coexpressed
R15631 T19325 T19326 themeOf luciferase,coexpressed
R15632 T19327 T19326 themeOf luciferase,coexpressed
R15633 T19333 T19331 causeOf IFN-γ,stimulated
R15634 T19335 T19336 themeOf luciferase,coexpressed
R15635 T19337 T19336 themeOf luciferase,coexpressed

GO-CC

Id Subject Object Predicate Lexical cue
T9881 39-44 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T9882 842-847 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T9883 2741-2746 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T9884 3018-3023 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T9885 3048-3053 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T9886 3136-3141 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T9887 3536-3541 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T9888 3836-3841 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T9889 3994-3998 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T19984 1219-1224 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T19985 1446-1451 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T19986 1593-1598 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T19987 2090-2095 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T19988 2523-2528 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

GO-MF

Id Subject Object Predicate Lexical cue
T9880 3720-3723 http://purl.obolibrary.org/obo/GO_0034005 denotes GAS
T19953 1497-1518 http://purl.obolibrary.org/obo/GO_0045289 denotes luciferase activities
T19954 1558-1579 http://purl.obolibrary.org/obo/GO_0045289 denotes luciferase activities
T19955 1912-1933 http://purl.obolibrary.org/obo/GO_0045289 denotes luciferase activities
T19956 1973-1994 http://purl.obolibrary.org/obo/GO_0045289 denotes luciferase activities
T19957 2429-2450 http://purl.obolibrary.org/obo/GO_0045289 denotes luciferase activities
T19958 2490-2511 http://purl.obolibrary.org/obo/GO_0045289 denotes luciferase activities
T19959 1497-1518 http://purl.obolibrary.org/obo/GO_0047077 denotes luciferase activities
T19960 1558-1579 http://purl.obolibrary.org/obo/GO_0047077 denotes luciferase activities
T19961 1912-1933 http://purl.obolibrary.org/obo/GO_0047077 denotes luciferase activities
T19962 1973-1994 http://purl.obolibrary.org/obo/GO_0047077 denotes luciferase activities
T19963 2429-2450 http://purl.obolibrary.org/obo/GO_0047077 denotes luciferase activities
T19964 2490-2511 http://purl.obolibrary.org/obo/GO_0047077 denotes luciferase activities
T19965 1497-1518 http://purl.obolibrary.org/obo/GO_0047712 denotes luciferase activities
T19966 1558-1579 http://purl.obolibrary.org/obo/GO_0047712 denotes luciferase activities
T19967 1912-1933 http://purl.obolibrary.org/obo/GO_0047712 denotes luciferase activities
T19968 1973-1994 http://purl.obolibrary.org/obo/GO_0047712 denotes luciferase activities
T19969 2429-2450 http://purl.obolibrary.org/obo/GO_0047712 denotes luciferase activities
T19970 2490-2511 http://purl.obolibrary.org/obo/GO_0047712 denotes luciferase activities
T19971 1497-1518 http://purl.obolibrary.org/obo/GO_0050248 denotes luciferase activities
T19972 1558-1579 http://purl.obolibrary.org/obo/GO_0050248 denotes luciferase activities
T19973 1912-1933 http://purl.obolibrary.org/obo/GO_0050248 denotes luciferase activities
T19974 1973-1994 http://purl.obolibrary.org/obo/GO_0050248 denotes luciferase activities
T19975 2429-2450 http://purl.obolibrary.org/obo/GO_0050248 denotes luciferase activities
T19976 2490-2511 http://purl.obolibrary.org/obo/GO_0050248 denotes luciferase activities
T19977 1497-1518 http://purl.obolibrary.org/obo/GO_0050397 denotes luciferase activities
T19978 1558-1579 http://purl.obolibrary.org/obo/GO_0050397 denotes luciferase activities
T19979 1912-1933 http://purl.obolibrary.org/obo/GO_0050397 denotes luciferase activities
T19980 1973-1994 http://purl.obolibrary.org/obo/GO_0050397 denotes luciferase activities
T19981 2429-2450 http://purl.obolibrary.org/obo/GO_0050397 denotes luciferase activities
T19982 2490-2511 http://purl.obolibrary.org/obo/GO_0050397 denotes luciferase activities
T19983 2219-2222 http://purl.obolibrary.org/obo/GO_0034005 denotes GAS

GO-BP

Id Subject Object Predicate Lexical cue
T8858 287-298 http://purl.obolibrary.org/obo/GO_0009056 denotes degradation
T8859 592-600 http://purl.obolibrary.org/obo/GO_0007349 denotes cellular
T8860 883-898 http://purl.obolibrary.org/obo/GO_0006351 denotes transcriptional
T8861 1075-1090 http://purl.obolibrary.org/obo/GO_0006351 denotes transcriptional
T8862 3224-3239 http://purl.obolibrary.org/obo/GO_0006351 denotes transcriptional
T8863 3720-3723 http://purl.obolibrary.org/obo/GO_0034005 denotes GAS
T19375 1497-1518 http://purl.obolibrary.org/obo/GO_0045289 denotes luciferase activities
T19376 1558-1579 http://purl.obolibrary.org/obo/GO_0045289 denotes luciferase activities
T19377 1912-1933 http://purl.obolibrary.org/obo/GO_0045289 denotes luciferase activities
T19378 1973-1994 http://purl.obolibrary.org/obo/GO_0045289 denotes luciferase activities
T19379 2429-2450 http://purl.obolibrary.org/obo/GO_0045289 denotes luciferase activities
T19380 2490-2511 http://purl.obolibrary.org/obo/GO_0045289 denotes luciferase activities
T19381 1497-1518 http://purl.obolibrary.org/obo/GO_0047077 denotes luciferase activities
T19382 1558-1579 http://purl.obolibrary.org/obo/GO_0047077 denotes luciferase activities
T19383 1912-1933 http://purl.obolibrary.org/obo/GO_0047077 denotes luciferase activities
T19384 1973-1994 http://purl.obolibrary.org/obo/GO_0047077 denotes luciferase activities
T19385 2429-2450 http://purl.obolibrary.org/obo/GO_0047077 denotes luciferase activities
T19386 2490-2511 http://purl.obolibrary.org/obo/GO_0047077 denotes luciferase activities
T19387 1497-1518 http://purl.obolibrary.org/obo/GO_0047712 denotes luciferase activities
T19388 1558-1579 http://purl.obolibrary.org/obo/GO_0047712 denotes luciferase activities
T19389 1912-1933 http://purl.obolibrary.org/obo/GO_0047712 denotes luciferase activities
T19390 1973-1994 http://purl.obolibrary.org/obo/GO_0047712 denotes luciferase activities
T19391 2429-2450 http://purl.obolibrary.org/obo/GO_0047712 denotes luciferase activities
T19392 2490-2511 http://purl.obolibrary.org/obo/GO_0047712 denotes luciferase activities
T19393 1497-1518 http://purl.obolibrary.org/obo/GO_0050248 denotes luciferase activities
T19394 1558-1579 http://purl.obolibrary.org/obo/GO_0050248 denotes luciferase activities
T19395 1912-1933 http://purl.obolibrary.org/obo/GO_0050248 denotes luciferase activities
T19396 1973-1994 http://purl.obolibrary.org/obo/GO_0050248 denotes luciferase activities
T19397 2429-2450 http://purl.obolibrary.org/obo/GO_0050248 denotes luciferase activities
T19398 2490-2511 http://purl.obolibrary.org/obo/GO_0050248 denotes luciferase activities
T19399 1497-1518 http://purl.obolibrary.org/obo/GO_0050397 denotes luciferase activities
T19400 1558-1579 http://purl.obolibrary.org/obo/GO_0050397 denotes luciferase activities
T19401 1912-1933 http://purl.obolibrary.org/obo/GO_0050397 denotes luciferase activities
T19402 1973-1994 http://purl.obolibrary.org/obo/GO_0050397 denotes luciferase activities
T19403 2429-2450 http://purl.obolibrary.org/obo/GO_0050397 denotes luciferase activities
T19404 2490-2511 http://purl.obolibrary.org/obo/GO_0050397 denotes luciferase activities
T19405 2219-2222 http://purl.obolibrary.org/obo/GO_0034005 denotes GAS

bionlp-st-ge-2016-spacy-parsed

Id Subject Object Predicate Lexical cue
T8815 81-89 NNP denotes APOBEC3G
T8816 90-95 VBZ denotes plays
T8817 96-97 DT denotes a
T8818 98-102 NN denotes role
T8819 103-105 IN denotes in
T8820 106-109 DT denotes the
T8821 110-116 NN denotes innate
T8822 117-124 NN denotes defence
T8823 125-132 IN denotes against
T8824 133-142 NNS denotes pathogens
T8825 143-147 IN denotes like
T8827 0-3 DT denotes The
T8828 4-7 NNP denotes A3G
T8829 8-16 NN denotes promoter
T8830 17-19 VBZ denotes is
T8831 20-23 RB denotes not
T8832 24-33 JJ denotes inducible
T8833 34-36 IN denotes in
T8834 37-38 NNP denotes T
T8835 39-44 NNS denotes cells
T8836 45-54 VBG denotes According
T8837 55-57 TO denotes to
T8838 58-61 DT denotes the
T8839 62-69 JJ denotes current
T8840 70-79 NN denotes knowledge
T9379 153-154 . denotes .
T9380 155-158 DT denotes The
T9381 159-165 JJ denotes latter
T9382 166-169 VBZ denotes has
T9383 170-177 VBN denotes evolved
T9384 178-179 DT denotes a
T9385 180-189 NN denotes mechanism
T9386 190-192 TO denotes to
T9387 193-203 VB denotes counteract
T9388 204-207 JJ denotes A3G
T9389 208-216 NN denotes activity
T9390 217-219 IN denotes by
T9391 220-230 VBG denotes expressing
T9392 231-234 DT denotes the
T9393 235-245 JJ denotes regulatory
T9394 246-253 NN denotes protein
T9395 254-257 NNP denotes Vif
T9396 258-259 -LRB- denotes (
T9397 259-260 LS denotes 4
T9398 260-261 -RRB- denotes )
T9399 261-262 . denotes .
T9400 263-266 NNP denotes Vif
T9401 267-274 VBZ denotes induces
T9402 275-286 JJ denotes proteasomal
T9403 287-298 NN denotes degradation
T9404 299-301 IN denotes of
T9405 302-305 NNP denotes A3G
T9406 306-309 CC denotes and
T9407 310-322 RB denotes additionally
T9408 323-331 VBZ denotes inhibits
T9409 332-335 JJ denotes A3G
T9410 336-344 NN denotes activity
T9411 345-347 IN denotes by
T9412 348-355 JJ denotes further
T9413 356-366 NNS denotes mechanisms
T9414 367-368 -LRB- denotes (
T9415 368-369 CD denotes 8
T9416 369-370 , denotes ,
T9417 371-373 CD denotes 37
T9418 374-376 CD denotes 43
T9419 376-377 -RRB- denotes )
T9420 377-378 . denotes .
T9421 379-381 TO denotes To
T9422 382-393 VB denotes investigate
T9423 394-401 IN denotes whether
T9424 402-405 DT denotes the
T9425 406-420 NN denotes overexpression
T9426 421-423 IN denotes of
T9427 424-429 JJ denotes HIV-1
T9428 430-438 NNS denotes proteins
T9429 439-443 RB denotes also
T9430 444-454 VBZ denotes influences
T9431 455-458 CD denotes A3G
T9432 459-467 NN denotes promoter
T9433 468-476 NN denotes activity
T9434 476-477 , denotes ,
T9435 478-480 PRP denotes we
T9436 481-487 RB denotes either
T9437 488-497 VBD denotes expressed
T9438 498-503 NNP denotes HIV-1
T9439 504-507 NNP denotes Vif
T9440 508-510 CC denotes or
T9441 511-514 DT denotes the
T9442 515-520 NNP denotes HIV-1
T9443 521-524 NNP denotes Tat
T9444 525-532 NN denotes protein
T9445 532-533 , denotes ,
T9446 534-537 DT denotes the
T9447 538-544 NN denotes latter
T9448 545-548 VBZ denotes has
T9449 549-553 VBN denotes been
T9450 554-559 VBN denotes shown
T9451 560-562 TO denotes to
T9452 563-571 VB denotes activate
T9453 572-581 JJ denotes different
T9454 582-587 JJ denotes viral
T9455 588-591 CC denotes and
T9456 592-600 JJ denotes cellular
T9457 601-610 NNS denotes promoters
T9458 611-612 -LRB- denotes (
T9459 612-617 CD denotes 44,45
T9460 617-618 -RRB- denotes )
T9461 618-619 . denotes .
T9462 620-622 IN denotes In
T9463 623-631 NN denotes addition
T9464 631-632 , denotes ,
T9465 633-643 VBG denotes increasing
T9466 644-651 NNS denotes amounts
T9467 652-654 IN denotes of
T9468 655-658 DT denotes the
T9469 659-666 JJ denotes plasmid
T9470 667-673 NN denotes pNL4-3
T9471 673-674 , denotes ,
T9472 675-685 VBG denotes containing
T9473 686-689 DT denotes the
T9474 690-701 JJ denotes full-length
T9475 702-708 NN denotes genome
T9476 709-711 IN denotes of
T9477 712-717 NNP denotes HIV-1
T9478 717-718 , denotes ,
T9479 719-723 VBD denotes were
T9480 724-735 VBN denotes transfected
T9481 735-736 . denotes .
T9482 737-742 DT denotes These
T9483 743-753 NNS denotes constructs
T9484 754-756 CC denotes or
T9485 757-760 DT denotes the
T9486 761-766 JJ denotes empty
T9487 767-773 NN denotes vector
T9488 774-780 NNP denotes pcDNA3
T9489 780-782 CD denotes .1
T9490 783-787 VBD denotes were
T9491 788-801 VBN denotes cotransfected
T9492 802-806 IN denotes with
T9493 807-810 DT denotes the
T9494 811-815 CD denotes 1025
T9495 816-818 NN denotes bp
T9496 819-828 VBP denotes construct
T9497 829-833 IN denotes into
T9498 834-836 CD denotes A3
T9499 836-839 CD denotes .01
T9500 840-841 NNP denotes T
T9501 842-847 NNS denotes cells
T9502 847-848 . denotes .
T9503 849-859 NNP denotes Luciferase
T9504 860-866 VBZ denotes assays
T9505 867-873 VBD denotes showed
T9506 874-878 IN denotes that
T9507 879-882 DT denotes the
T9508 883-898 JJ denotes transcriptional
T9509 899-907 NN denotes activity
T9510 908-910 IN denotes of
T9511 911-914 DT denotes the
T9512 915-918 NNP denotes A3G
T9513 919-927 NN denotes promoter
T9514 928-931 VBD denotes was
T9515 932-935 RB denotes not
T9516 936-949 RB denotes significantly
T9517 950-957 VBN denotes altered
T9518 958-960 IN denotes in
T9519 961-964 DT denotes the
T9520 965-973 NN denotes presence
T9521 974-976 IN denotes of
T9522 977-980 NNP denotes Vif
T9523 980-981 , denotes ,
T9524 982-985 NNP denotes Tat
T9525 986-988 CC denotes or
T9526 989-999 NNP denotes HIV-1NL4-3
T9527 1000-1001 -LRB- denotes (
T9528 1001-1007 NNP denotes Figure
T9529 1008-1010 NNP denotes 4A
T9530 1010-1011 -RRB- denotes )
T9531 1011-1012 , denotes ,
T9532 1013-1023 VBG denotes suggesting
T9533 1024-1028 IN denotes that
T9534 1029-1034 NNP denotes HIV-1
T9535 1035-1037 VBZ denotes is
T9536 1038-1041 RB denotes not
T9537 1042-1052 VBG denotes modulating
T9538 1053-1056 NNP denotes A3G
T9539 1057-1067 NN denotes expression
T9540 1068-1070 IN denotes on
T9541 1071-1074 DT denotes the
T9542 1075-1090 JJ denotes transcriptional
T9543 1091-1096 NN denotes level
T9544 1096-1097 . denotes .
T9545 2690-2692 PRP denotes It
T9546 2693-2696 VBZ denotes has
T9547 2697-2701 VBN denotes been
T9548 2702-2707 VBN denotes shown
T9549 2708-2712 IN denotes that
T9550 2713-2716 DT denotes the
T9551 2717-2723 NN denotes amount
T9552 2724-2726 IN denotes of
T9553 2727-2730 NNP denotes A3G
T9554 2731-2735 NNP denotes mRNA
T9555 2736-2738 IN denotes in
T9556 2739-2740 NNP denotes T
T9557 2741-2746 NNS denotes cells
T9558 2747-2749 VBZ denotes is
T9559 2750-2759 VBN denotes increased
T9560 2760-2762 IN denotes in
T9561 2763-2771 NN denotes response
T9562 2772-2774 TO denotes to
T9563 2775-2784 JJ denotes mitogenic
T9564 2785-2796 NN denotes stimulation
T9565 2797-2801 IN denotes with
T9566 2802-2809 NN denotes phorbol
T9567 2810-2815 NN denotes ester
T9568 2816-2817 -LRB- denotes (
T9569 2817-2819 CD denotes 46
T9570 2820-2822 CD denotes 48
T9571 2822-2823 -RRB- denotes )
T9572 2823-2824 . denotes .
T9573 2825-2827 IN denotes In
T9574 2828-2836 NN denotes addition
T9575 2836-2837 , denotes ,
T9576 2838-2849 NNS denotes interferons
T9577 2850-2854 VBP denotes have
T9578 2855-2859 VBN denotes been
T9579 2860-2869 VBN denotes described
T9580 2870-2872 TO denotes to
T9581 2873-2883 VB denotes upregulate
T9582 2884-2887 NNP denotes A3G
T9583 2888-2898 NN denotes expression
T9584 2899-2901 IN denotes in
T9585 2902-2913 NNS denotes hepatocytes
T9586 2914-2917 CC denotes and
T9587 2918-2929 NNS denotes macrophages
T9588 2930-2931 -LRB- denotes (
T9589 2931-2936 CD denotes 46,48
T9590 2936-2937 -RRB- denotes )
T9591 2937-2938 . denotes .
T9592 2939-2941 TO denotes To
T9593 2942-2953 VB denotes investigate
T9594 2954-2961 IN denotes whether
T9595 2962-2967 DT denotes these
T9596 2968-2975 NNS denotes stimuli
T9597 2976-2985 VBP denotes interfere
T9598 2986-2990 IN denotes with
T9599 2991-2994 CD denotes A3G
T9600 2995-3003 NN denotes promoter
T9601 3004-3012 NN denotes activity
T9602 3013-3015 IN denotes in
T9603 3016-3017 NNP denotes T
T9604 3018-3023 NNS denotes cells
T9605 3023-3024 , denotes ,
T9606 3025-3027 PRP denotes we
T9607 3028-3039 VBD denotes transfected
T9608 3040-3042 NNP denotes A3
T9609 3042-3045 CD denotes .01
T9610 3046-3047 NNP denotes T
T9611 3048-3053 NNS denotes cells
T9612 3054-3058 IN denotes with
T9613 3059-3062 DT denotes the
T9614 3063-3067 CD denotes 1025
T9615 3068-3070 NN denotes bp
T9616 3071-3079 NN denotes promoter
T9617 3080-3082 CC denotes or
T9618 3083-3086 DT denotes the
T9619 3087-3092 JJ denotes empty
T9620 3093-3099 NN denotes vector
T9621 3100-3110 JJ denotes pGL3-Basic
T9622 3111-3112 -LRB- denotes (
T9623 3112-3118 NN denotes vector
T9624 3118-3119 -RRB- denotes )
T9625 3120-3123 CC denotes and
T9626 3124-3131 VBD denotes treated
T9627 3132-3135 DT denotes the
T9628 3136-3141 NNS denotes cells
T9629 3142-3146 IN denotes with
T9630 3147-3154 NN denotes phorbol
T9631 3155-3160 NN denotes ester
T9632 3161-3162 -LRB- denotes (
T9633 3162-3165 NNP denotes TPA
T9634 3165-3166 -RRB- denotes )
T9635 3166-3167 . denotes .
T9636 3168-3171 DT denotes The
T9637 3172-3182 NN denotes luciferase
T9638 3183-3188 NN denotes assay
T9639 3189-3195 VBD denotes showed
T9640 3196-3200 IN denotes that
T9641 3201-3204 DT denotes the
T9642 3205-3206 NN denotes ∼
T9643 3206-3213 JJ denotes 15-fold
T9644 3214-3223 VBN denotes increased
T9645 3224-3239 JJ denotes transcriptional
T9646 3240-3248 NN denotes activity
T9647 3249-3251 IN denotes of
T9648 3252-3255 DT denotes the
T9649 3256-3260 CD denotes 1025
T9650 3261-3263 NN denotes bp
T9651 3264-3272 NN denotes promoter
T9652 3273-3281 JJ denotes relative
T9653 3282-3284 TO denotes to
T9654 3285-3288 DT denotes the
T9655 3289-3294 JJ denotes empty
T9656 3295-3301 NN denotes vector
T9657 3302-3305 VBD denotes was
T9658 3306-3309 RB denotes not
T9659 3310-3317 JJ denotes further
T9660 3318-3326 VBN denotes enhanced
T9661 3327-3329 IN denotes by
T9662 3330-3333 NNP denotes TPA
T9663 3334-3343 NN denotes treatment
T9664 3344-3345 -LRB- denotes (
T9665 3345-3351 NN denotes Figure
T9666 3352-3354 NN denotes 4B
T9667 3354-3355 -RRB- denotes )
T9668 3355-3356 , denotes ,
T9669 3357-3365 IN denotes although
T9670 3366-3369 DT denotes the
T9671 3370-3380 JJ denotes functional
T9672 3381-3389 NN denotes activity
T9673 3390-3392 IN denotes of
T9674 3393-3396 NNP denotes TPA
T9675 3397-3400 VBD denotes was
T9676 3401-3410 VBN denotes confirmed
T9677 3411-3413 IN denotes by
T9678 3414-3423 NN denotes induction
T9679 3424-3426 IN denotes of
T9680 3427-3430 DT denotes the
T9681 3431-3435 NNP denotes SV40
T9682 3436-3455 NN denotes promoter-containing
T9683 3456-3464 NN denotes reporter
T9684 3465-3472 JJ denotes plasmid
T9685 3473-3485 NN denotes pGL3-Control
T9686 3486-3487 -LRB- denotes (
T9687 3487-3491 NNS denotes data
T9688 3492-3495 RB denotes not
T9689 3496-3501 VBN denotes shown
T9690 3501-3502 -RRB- denotes )
T9691 3502-3503 . denotes .
T9692 3504-3513 RB denotes Similarly
T9693 3513-3514 , denotes ,
T9694 3515-3524 NN denotes treatment
T9695 3525-3527 IN denotes of
T9696 3528-3530 CD denotes A3
T9697 3530-3533 CD denotes .01
T9698 3534-3535 NNP denotes T
T9699 3536-3541 NNS denotes cells
T9700 3542-3553 VBN denotes transfected
T9701 3554-3558 IN denotes with
T9702 3559-3562 DT denotes the
T9703 3563-3566 NNP denotes A3G
T9704 3567-3575 NN denotes promoter
T9705 3576-3584 NN denotes deletion
T9706 3585-3595 NNS denotes constructs
T9707 3596-3600 IN denotes with
T9708 3601-3606 JJ denotes IFN-α
T9726 3607-3609 CC denotes or
T9727 3610-3615 JJ denotes IFN-γ
T9728 3616-3622 VBD denotes showed
T9729 3623-3625 DT denotes no
T9730 3626-3632 NN denotes effect
T9731 3633-3634 -LRB- denotes (
T9732 3634-3640 NN denotes Figure
T9733 3641-3643 NN denotes 4C
T9734 3643-3644 -RRB- denotes )
T9735 3644-3645 . denotes .
T9736 3646-3659 RB denotes Interestingly
T9737 3659-3660 , denotes ,
T9738 3661-3662 DT denotes a
T9739 3663-3670 NN denotes control
T9740 3671-3678 NN denotes plasmid
T9741 3679-3680 -LRB- denotes (
T9742 3680-3688 NN denotes pGL2-CVX
T9743 3688-3689 -RRB- denotes )
T9744 3690-3700 VBG denotes containing
T9745 3701-3704 CD denotes two
T9746 3705-3719 JJ denotes IFN-responsive
T9747 3720-3723 NNP denotes GAS
T9748 3724-3725 -LRB- denotes (
T9749 3725-3730 NN denotes gamma
T9750 3731-3740 VBN denotes activated
T9751 3741-3749 NN denotes sequence
T9752 3749-3750 -RRB- denotes )
T9753 3751-3759 NNS denotes elements
T9754 3760-3768 RB denotes upstream
T9755 3769-3771 IN denotes of
T9756 3772-3775 DT denotes the
T9757 3776-3786 NN denotes luciferase
T9758 3787-3795 NN denotes reporter
T9759 3796-3800 NN denotes gene
T9760 3801-3804 VBD denotes was
T9761 3805-3809 RB denotes only
T9762 3810-3817 JJ denotes induced
T9763 3818-3820 IN denotes by
T9764 3821-3826 NNP denotes IFN-α
T9765 3827-3829 IN denotes in
T9766 3830-3835 DT denotes these
T9767 3836-3841 NNS denotes cells
T9768 3842-3843 -LRB- denotes (
T9769 3843-3849 NN denotes Figure
T9770 3850-3852 NN denotes 4C
T9771 3852-3853 -RRB- denotes )
T9772 3853-3854 . denotes .
T9773 3855-3860 IN denotes Since
T9774 3861-3864 CD denotes two
T9775 3865-3872 NNS denotes reports
T9776 3873-3881 VBP denotes describe
T9777 3882-3885 NNP denotes A3G
T9778 3886-3898 NN denotes upregulation
T9779 3899-3901 IN denotes by
T9780 3902-3913 NNS denotes interferons
T9781 3914-3916 IN denotes in
T9782 3917-3928 NNS denotes hepatocytes
T9783 3929-3930 -LRB- denotes (
T9784 3930-3935 CD denotes 47,48
T9785 3935-3936 -RRB- denotes )
T9786 3936-3937 , denotes ,
T9787 3938-3940 PRP denotes we
T9788 3941-3953 RB denotes additionally
T9789 3954-3963 VBD denotes performed
T9790 3964-3967 DT denotes the
T9791 3968-3978 NN denotes experiment
T9792 3979-3981 IN denotes in
T9793 3982-3985 DT denotes the
T9794 3986-3993 JJ denotes hepatic
T9795 3994-3998 NN denotes cell
T9796 3999-4003 NN denotes line
T9797 4004-4009 NNP denotes HepG2
T9798 4009-4010 . denotes .
T9799 4011-4013 IN denotes In
T9800 4014-4018 NN denotes line
T9801 4019-4023 IN denotes with
T9802 4024-4029 DT denotes these
T9803 4030-4042 NNS denotes publications
T9804 4042-4043 , denotes ,
T9805 4044-4046 PRP denotes we
T9806 4047-4055 VBD denotes observed
T9807 4056-4058 DT denotes an
T9808 4059-4068 NN denotes induction
T9809 4069-4071 IN denotes of
T9810 4072-4075 DT denotes the
T9811 4076-4079 NNP denotes A3G
T9812 4080-4088 NN denotes promoter
T9813 4089-4091 IN denotes by
T9814 4092-4105 RB denotes approximately
T9815 4106-4112 JJ denotes 2-fold
T9816 4113-4118 IN denotes after
T9817 4119-4124 JJ denotes IFN-α
T9818 4125-4127 CC denotes or
T9819 4128-4133 JJ denotes IFN-γ
T9820 4134-4145 NN denotes stimulation
T9821 4146-4147 -LRB- denotes (
T9822 4147-4153 NN denotes Figure
T9823 4154-4156 CD denotes 4D
T9824 4156-4157 -RRB- denotes )
T9825 4158-4162 IN denotes with
T9826 4163-4168 NNP denotes IFN-γ
T9827 4169-4174 VBG denotes being
T9828 4175-4183 RB denotes slightly
T9829 4184-4188 RBR denotes more
T9830 4189-4195 JJ denotes potent
T9831 4195-4196 . denotes .
T9832 4197-4200 IN denotes For
T9833 4201-4205 DT denotes both
T9834 4206-4216 NN denotes interferon
T9835 4217-4222 NNS denotes types
T9836 4222-4223 , denotes ,
T9837 4224-4233 NN denotes induction
T9838 4234-4236 IN denotes of
T9839 4237-4240 NNP denotes A3G
T9840 4241-4249 NN denotes promoter
T9841 4250-4258 NN denotes activity
T9842 4259-4262 VBD denotes was
T9843 4263-4271 VBN denotes observed
T9844 4272-4275 IN denotes for
T9845 4276-4279 DT denotes all
T9846 4280-4288 NN denotes deletion
T9847 4289-4299 VBZ denotes constructs
T9848 4300-4306 IN denotes except
T9849 4307-4310 IN denotes for
T9850 4311-4314 DT denotes the
T9851 4315-4317 CD denotes 60
T9852 4318-4320 NN denotes bp
T9853 4321-4329 NN denotes fragment
T9854 4329-4330 , denotes ,
T9855 4331-4341 VBG denotes indicating
T9856 4342-4346 IN denotes that
T9857 4347-4350 DT denotes the
T9858 4351-4362 JJ denotes responsible
T9859 4363-4369 NN denotes region
T9860 4370-4372 VBZ denotes is
T9861 4373-4380 VBN denotes located
T9862 4381-4387 IN denotes within
T9863 4388-4391 DT denotes the
T9864 4392-4394 CD denotes 60
T9865 4395-4397 NN denotes nt
T9866 4398-4405 NN denotes present
T9867 4406-4408 IN denotes in
T9868 4409-4412 DT denotes the
T9869 4413-4416 CD denotes 120
T9870 4417-4419 NN denotes bp
T9871 4419-4420 , denotes ,
T9872 4421-4424 CC denotes but
T9873 4425-4428 RB denotes not
T9874 4429-4431 IN denotes in
T9875 4432-4435 DT denotes the
T9876 4436-4438 CD denotes 60
T9877 4439-4441 NN denotes bp
T9878 4442-4450 NN denotes fragment
T9879 4450-4451 . denotes .
T19681 1108-1111 CD denotes A3G
T19682 1112-1120 NN denotes promoter
T19683 1121-1131 NNS denotes activities
T19684 1132-1137 IN denotes after
T19685 1138-1150 NN denotes coexpression
T19686 1151-1153 IN denotes of
T19687 1154-1159 JJ denotes HIV-1
T19688 1160-1168 NNS denotes proteins
T19689 1169-1171 CC denotes or
T19690 1172-1181 NN denotes treatment
T19691 1182-1186 IN denotes with
T19692 1187-1190 NNP denotes TPA
T19693 1191-1193 CC denotes or
T19694 1194-1205 NNS denotes interferons
T19695 1205-1206 . denotes .
T19696 1207-1208 -LRB- denotes (
T19697 1208-1209 NNP denotes A
T19698 1209-1210 -RRB- denotes )
T19699 1211-1213 NNP denotes A3
T19700 1213-1216 CD denotes .01
T19701 1217-1218 NNP denotes T
T19702 1219-1224 NNS denotes cells
T19703 1225-1229 VBD denotes were
T19704 1230-1243 VBN denotes cotransfected
T19705 1244-1248 IN denotes with
T19706 1249-1259 JJ denotes pGL3-Basic
T19707 1260-1268 NN denotes reporter
T19708 1269-1276 NN denotes plasmid
T19709 1277-1287 VBG denotes containing
T19710 1288-1291 DT denotes the
T19711 1292-1296 CD denotes 1025
T19712 1297-1299 NN denotes bp
T19713 1300-1303 CD denotes A3G
T19714 1304-1312 NN denotes promoter
T19715 1313-1316 CC denotes and
T19716 1317-1318 CD denotes 1
T19717 1319-1321 NN denotes µg
T19718 1322-1324 IN denotes of
T19719 1325-1328 NNP denotes Vif
T19720 1329-1339 NN denotes expression
T19721 1340-1347 NN denotes plasmid
T19722 1347-1348 , denotes ,
T19723 1349-1350 CD denotes 1
T19724 1351-1353 NN denotes µg
T19725 1354-1357 NNP denotes Tat
T19726 1358-1368 NN denotes expression
T19727 1369-1376 NN denotes plasmid
T19728 1377-1379 CC denotes or
T19729 1380-1390 VBG denotes increasing
T19730 1391-1398 NNS denotes amounts
T19731 1399-1401 IN denotes of
T19732 1402-1412 NNP denotes HIV-1NL4-3
T19733 1413-1414 -LRB- denotes (
T19734 1414-1417 CD denotes 0.1
T19735 1417-1418 , denotes ,
T19736 1419-1422 CD denotes 0.5
T19737 1423-1426 CC denotes and
T19738 1427-1428 CD denotes 1
T19739 1429-1431 NN denotes µg
T19740 1431-1432 -RRB- denotes )
T19741 1432-1433 . denotes .
T19742 1434-1439 IN denotes After
T19743 1440-1442 CD denotes 48
T19744 1443-1444 NN denotes h
T19745 1444-1445 , denotes ,
T19746 1446-1451 NNS denotes cells
T19747 1452-1456 VBD denotes were
T19748 1457-1466 VBN denotes harvested
T19749 1467-1470 IN denotes for
T19750 1471-1481 NN denotes luciferase
T19751 1482-1487 NN denotes assay
T19752 1487-1488 . denotes .
T19753 1489-1496 RB denotes Firefly
T19754 1497-1507 JJ denotes luciferase
T19755 1508-1518 NNS denotes activities
T19756 1519-1523 VBD denotes were
T19757 1524-1534 VBN denotes normalized
T19758 1535-1537 TO denotes to
T19759 1538-1549 VBN denotes coexpressed
T19760 1550-1557 NN denotes renilla
T19761 1558-1568 NN denotes luciferase
T19762 1569-1579 NNS denotes activities
T19763 1579-1580 . denotes .
T19764 1581-1582 -LRB- denotes (
T19765 1582-1583 NNP denotes B
T19766 1583-1584 -RRB- denotes )
T19767 1585-1587 NNP denotes A3
T19768 1587-1590 CD denotes .01
T19769 1591-1592 NNP denotes T
T19770 1593-1598 NNS denotes cells
T19771 1599-1603 VBD denotes were
T19772 1604-1615 RB denotes transiently
T19773 1616-1627 VBN denotes transfected
T19774 1628-1632 IN denotes with
T19775 1633-1643 JJ denotes pGL3-Basic
T19776 1644-1652 NN denotes reporter
T19777 1653-1660 NN denotes plasmid
T19778 1661-1671 VBG denotes containing
T19779 1672-1675 DT denotes the
T19780 1676-1680 CD denotes 1025
T19781 1681-1683 NN denotes bp
T19782 1684-1687 CD denotes A3G
T19783 1688-1696 NN denotes promoter
T19784 1697-1699 CC denotes or
T19785 1700-1704 IN denotes with
T19786 1705-1710 JJ denotes empty
T19787 1711-1717 NN denotes vector
T19788 1717-1718 . denotes .
T19789 1719-1726 CD denotes Fifteen
T19790 1727-1731 NN denotes hour
T19791 1732-1738 IN denotes before
T19792 1739-1749 VBG denotes harvesting
T19793 1750-1753 IN denotes for
T19794 1754-1764 NN denotes luciferase
T19795 1765-1770 NN denotes assay
T19796 1770-1771 , denotes ,
T19797 1772-1773 DT denotes a
T19798 1774-1780 NN denotes subset
T19799 1781-1783 IN denotes of
T19800 1784-1787 DT denotes the
T19801 1788-1792 NN denotes cell
T19802 1793-1800 NN denotes culture
T19803 1801-1804 VBD denotes was
T19804 1805-1815 VBN denotes stimulated
T19805 1816-1820 IN denotes with
T19806 1821-1823 CD denotes 20
T19807 1824-1829 NN denotes ng/ml
T19808 1830-1833 NNP denotes TPA
T19809 1833-1834 . denotes .
T19810 1835-1846 JJ denotes Forty-eight
T19811 1847-1851 NN denotes hour
T19812 1852-1857 IN denotes after
T19813 1858-1870 NN denotes transfection
T19814 1870-1871 , denotes ,
T19815 1872-1882 NN denotes luciferase
T19816 1883-1888 NN denotes assay
T19817 1889-1892 VBD denotes was
T19818 1893-1902 VBN denotes performed
T19819 1902-1903 . denotes .
T19820 1904-1911 RB denotes Firefly
T19821 1912-1922 JJ denotes luciferase
T19822 1923-1933 NNS denotes activities
T19823 1934-1938 VBD denotes were
T19824 1939-1949 VBN denotes normalized
T19825 1950-1952 TO denotes to
T19826 1953-1964 VBN denotes coexpressed
T19827 1965-1972 NN denotes renilla
T19828 1973-1983 NN denotes luciferase
T19829 1984-1994 NNS denotes activities
T19830 1995-1998 CC denotes and
T19831 1999-2002 DT denotes the
T19832 2003-2009 NNS denotes values
T19833 2010-2013 IN denotes for
T19834 2014-2017 DT denotes the
T19835 2018-2023 JJ denotes empty
T19836 2024-2031 NNS denotes vectors
T19837 2032-2033 -LRB- denotes (
T19838 2033-2042 JJ denotes untreated
T19839 2043-2046 CC denotes and
T19840 2047-2061 JJ denotes TPA-stimulated
T19841 2061-2062 -RRB- denotes )
T19842 2063-2067 VBD denotes were
T19843 2068-2071 VBN denotes set
T19844 2072-2074 IN denotes as
T19845 2075-2076 CD denotes 1
T19846 2076-2077 . denotes .
T19847 2078-2079 -LRB- denotes (
T19848 2079-2080 $ denotes C
T19849 2080-2081 -RRB- denotes )
T19850 2082-2084 CD denotes A3
T19851 2084-2087 CD denotes .01
T19852 2088-2089 NNP denotes T
T19853 2090-2095 NNS denotes cells
T19854 2096-2100 VBD denotes were
T19855 2101-2112 RB denotes transiently
T19856 2113-2124 VBN denotes transfected
T19857 2125-2129 IN denotes with
T19858 2130-2133 DT denotes the
T19859 2134-2137 NNP denotes A3G
T19860 2138-2146 NN denotes promoter
T19861 2147-2157 NNS denotes constructs
T19862 2158-2160 CC denotes or
T19863 2161-2165 IN denotes with
T19864 2166-2169 DT denotes the
T19865 2170-2191 JJ denotes interferon-responsive
T19866 2192-2200 NN denotes reporter
T19867 2201-2208 NN denotes plasmid
T19868 2209-2217 NN denotes pGL2-CVX
T19869 2218-2219 -LRB- denotes (
T19870 2219-2222 NNP denotes GAS
T19871 2222-2223 -RRB- denotes )
T19872 2223-2224 . denotes .
T19873 2225-2232 CD denotes Fifteen
T19874 2233-2237 NN denotes hour
T19875 2238-2244 IN denotes before
T19876 2245-2255 VBG denotes harvesting
T19877 2256-2259 IN denotes for
T19878 2260-2270 NN denotes luciferase
T19879 2271-2276 NN denotes assay
T19880 2276-2277 , denotes ,
T19881 2278-2279 DT denotes a
T19882 2280-2286 NN denotes subset
T19883 2287-2289 IN denotes of
T19884 2290-2293 DT denotes the
T19885 2294-2298 NN denotes cell
T19886 2299-2306 NN denotes culture
T19887 2307-2310 VBD denotes was
T19888 2311-2321 VBN denotes stimulated
T19889 2322-2326 IN denotes with
T19890 2327-2329 CD denotes 30
T19891 2330-2335 NN denotes ng/ml
T19892 2336-2341 NN denotes IFN-α
T19893 2342-2344 CC denotes or
T19894 2345-2350 NN denotes IFN-γ
T19895 2350-2351 . denotes .
T19896 2352-2363 JJ denotes Forty-eight
T19897 2364-2368 NN denotes hour
T19898 2369-2374 IN denotes after
T19899 2375-2387 NN denotes transfection
T19900 2387-2388 , denotes ,
T19901 2389-2399 NN denotes luciferase
T19902 2400-2405 NN denotes assay
T19903 2406-2409 VBD denotes was
T19904 2410-2419 VBN denotes performed
T19905 2419-2420 . denotes .
T19906 2421-2428 RB denotes Firefly
T19907 2429-2439 JJ denotes luciferase
T19908 2440-2450 NNS denotes activities
T19909 2451-2455 VBD denotes were
T19910 2456-2466 VBN denotes normalized
T19911 2467-2469 TO denotes to
T19912 2470-2481 VBN denotes coexpressed
T19913 2482-2489 NN denotes renilla
T19914 2490-2500 NN denotes luciferase
T19915 2501-2511 NNS denotes activities
T19916 2511-2512 . denotes .
T19917 2513-2514 -LRB- denotes (
T19918 2514-2515 NNP denotes D
T19919 2515-2516 -RRB- denotes )
T19920 2517-2522 JJ denotes HepG2
T19921 2523-2528 NNS denotes cells
T19922 2529-2533 VBD denotes were
T19923 2534-2538 VBN denotes used
T19924 2539-2542 IN denotes for
T19925 2543-2555 NN denotes transfection
T19926 2555-2556 . denotes .
T19927 2557-2560 DT denotes The
T19928 2561-2571 NN denotes experiment
T19929 2572-2575 VBD denotes was
T19930 2576-2585 VBN denotes performed
T19931 2586-2588 IN denotes as
T19932 2589-2598 VBN denotes described
T19933 2599-2601 IN denotes in
T19934 2602-2603 -LRB- denotes (
T19935 2603-2604 NNP denotes C
T19936 2604-2605 -RRB- denotes )
T19937 2605-2606 . denotes .
T19938 2607-2611 VB denotes Mean
T19939 2612-2618 NNS denotes values
T19940 2619-2620 -LRB- denotes (
T19941 2620-2621 CD denotes ±
T19942 2621-2623 NNP denotes SD
T19943 2623-2624 -RRB- denotes )
T19944 2625-2627 IN denotes of
T19945 2628-2642 NN denotes representative
T19946 2643-2654 NNS denotes experiments
T19947 2655-2664 VBN denotes performed
T19948 2665-2667 IN denotes in
T19949 2668-2678 NN denotes triplicate
T19950 2679-2682 VBP denotes are
T19951 2683-2688 VBN denotes shown
T19952 2688-2689 . denotes .
T8814 79-80 , denotes ,
T8826 148-153 NN denotes HIV-1
R7204 T8814 T8816 punct ",",plays
R7205 T8815 T8816 nsubj APOBEC3G,plays
R7206 T8816 T8816 ROOT plays,plays
R7207 T8817 T8818 det a,role
R7208 T8818 T8816 dobj role,plays
R7209 T8819 T8818 prep in,role
R7210 T8820 T8822 det the,defence
R7211 T8821 T8822 amod innate,defence
R7212 T8822 T8819 pobj defence,in
R7213 T8823 T8818 prep against,role
R7214 T8824 T8823 pobj pathogens,against
R7215 T8825 T8824 prep like,pathogens
R7216 T8826 T8825 pobj HIV-1,like
R7217 T8827 T8829 det The,promoter
R7218 T8828 T8829 compound A3G,promoter
R7219 T8829 T8830 nsubj promoter,is
R7220 T8830 T8816 ccomp is,plays
R7221 T8831 T8830 neg not,is
R7222 T8832 T8830 acomp inducible,is
R7223 T8833 T8832 prep in,inducible
R7224 T8834 T8835 compound T,cells
R7225 T8835 T8833 pobj cells,in
R7226 T8836 T8816 prep According,plays
R7227 T8837 T8836 prep to,According
R7228 T8838 T8840 det the,knowledge
R7229 T8839 T8840 amod current,knowledge
R7230 T8840 T8837 pobj knowledge,to
R7720 T9379 T8816 punct .,plays
R7721 T9380 T9381 det The,latter
R7722 T9381 T9383 nsubj latter,evolved
R7723 T9382 T9383 aux has,evolved
R7724 T9383 T9383 ROOT evolved,evolved
R7725 T9384 T9385 det a,mechanism
R7726 T9385 T9383 dobj mechanism,evolved
R7727 T9386 T9387 aux to,counteract
R7728 T9387 T9385 relcl counteract,mechanism
R7729 T9388 T9389 amod A3G,activity
R7730 T9389 T9387 dobj activity,counteract
R7731 T9390 T9387 prep by,counteract
R7732 T9391 T9390 pcomp expressing,by
R7733 T9392 T9394 det the,protein
R7734 T9393 T9394 amod regulatory,protein
R7735 T9394 T9391 dobj protein,expressing
R7736 T9395 T9394 appos Vif,protein
R7737 T9396 T9397 punct (,4
R7738 T9397 T9395 appos 4,Vif
R7739 T9398 T9397 punct ),4
R7740 T9399 T9383 punct .,evolved
R7741 T9400 T9401 nsubj Vif,induces
R7742 T9401 T9401 ROOT induces,induces
R7743 T9402 T9403 amod proteasomal,degradation
R7744 T9403 T9401 dobj degradation,induces
R7745 T9404 T9403 prep of,degradation
R7746 T9405 T9404 pobj A3G,of
R7747 T9406 T9401 cc and,induces
R7748 T9407 T9408 advmod additionally,inhibits
R7749 T9408 T9401 conj inhibits,induces
R7750 T9409 T9410 amod A3G,activity
R7751 T9410 T9408 dobj activity,inhibits
R7752 T9411 T9408 prep by,inhibits
R7753 T9412 T9413 amod further,mechanisms
R7754 T9413 T9411 pobj mechanisms,by
R7755 T9414 T9413 punct (,mechanisms
R7756 T9415 T9417 quantmod 8,37
R7757 T9416 T9417 punct ",",37
R7758 T9417 T9413 appos 37,mechanisms
R7759 T9418 T9417 appos 43,37
R7760 T9419 T9417 punct ),37
R7761 T9420 T9401 punct .,induces
R7762 T9421 T9422 aux To,investigate
R7763 T9422 T9437 advcl investigate,expressed
R7764 T9423 T9430 mark whether,influences
R7765 T9424 T9425 det the,overexpression
R7766 T9425 T9430 nsubj overexpression,influences
R7767 T9426 T9425 prep of,overexpression
R7768 T9427 T9428 compound HIV-1,proteins
R7769 T9428 T9426 pobj proteins,of
R7770 T9429 T9430 advmod also,influences
R7771 T9430 T9437 advcl influences,expressed
R7772 T9431 T9433 nummod A3G,activity
R7773 T9432 T9433 compound promoter,activity
R7774 T9433 T9430 dobj activity,influences
R7775 T9434 T9437 punct ",",expressed
R7776 T9435 T9437 nsubj we,expressed
R7777 T9436 T9437 preconj either,expressed
R7778 T9437 T9437 ROOT expressed,expressed
R7779 T9438 T9439 compound HIV-1,Vif
R7780 T9439 T9437 dobj Vif,expressed
R7781 T9440 T9439 cc or,Vif
R7782 T9441 T9444 det the,protein
R7783 T9442 T9443 compound HIV-1,Tat
R7784 T9443 T9444 compound Tat,protein
R7785 T9444 T9439 conj protein,Vif
R7786 T9445 T9450 punct ",",shown
R7787 T9446 T9447 det the,latter
R7788 T9447 T9450 nsubjpass latter,shown
R7789 T9448 T9450 aux has,shown
R7790 T9449 T9450 auxpass been,shown
R7791 T9450 T9437 conj shown,expressed
R7792 T9451 T9452 aux to,activate
R7793 T9452 T9450 xcomp activate,shown
R7794 T9453 T9457 amod different,promoters
R7795 T9454 T9457 amod viral,promoters
R7796 T9455 T9454 cc and,viral
R7797 T9456 T9454 conj cellular,viral
R7798 T9457 T9452 dobj promoters,activate
R7799 T9458 T9457 punct (,promoters
R7800 T9459 T9457 appos "44,45",promoters
R7801 T9460 T9457 punct ),promoters
R7802 T9461 T9450 punct .,shown
R7803 T9462 T9480 prep In,transfected
R7804 T9463 T9462 pobj addition,In
R7805 T9464 T9480 punct ",",transfected
R7806 T9465 T9480 csubjpass increasing,transfected
R7807 T9466 T9465 dobj amounts,increasing
R7808 T9467 T9466 prep of,amounts
R7809 T9468 T9470 det the,pNL4-3
R7810 T9469 T9470 compound plasmid,pNL4-3
R7811 T9470 T9467 pobj pNL4-3,of
R7812 T9471 T9465 punct ",",increasing
R7813 T9472 T9465 prep containing,increasing
R7814 T9473 T9475 det the,genome
R7815 T9474 T9475 amod full-length,genome
R7816 T9475 T9472 dobj genome,containing
R7817 T9476 T9475 prep of,genome
R7818 T9477 T9476 pobj HIV-1,of
R7819 T9478 T9479 punct ",",were
R7820 T9479 T9480 auxpass were,transfected
R7821 T9480 T9480 ROOT transfected,transfected
R7822 T9481 T9480 punct .,transfected
R7823 T9482 T9483 det These,constructs
R7824 T9483 T9491 nsubjpass constructs,cotransfected
R7825 T9484 T9483 cc or,constructs
R7826 T9485 T9487 det the,vector
R7827 T9486 T9487 amod empty,vector
R7828 T9487 T9483 conj vector,constructs
R7829 T9488 T9489 compound pcDNA3,.1
R7830 T9489 T9487 appos .1,vector
R7831 T9490 T9491 auxpass were,cotransfected
R7832 T9491 T9491 ROOT cotransfected,cotransfected
R7833 T9492 T9491 prep with,cotransfected
R7834 T9493 T9495 det the,bp
R7835 T9494 T9495 nummod 1025,bp
R7836 T9495 T9492 pobj bp,with
R7837 T9496 T9491 conj construct,cotransfected
R7838 T9497 T9496 prep into,construct
R7839 T9498 T9501 nummod A3,cells
R7840 T9499 T9501 nummod .01,cells
R7841 T9500 T9501 compound T,cells
R7842 T9501 T9497 pobj cells,into
R7843 T9502 T9491 punct .,cotransfected
R7844 T9503 T9504 compound Luciferase,assays
R7845 T9504 T9505 nsubj assays,showed
R7846 T9505 T9505 ROOT showed,showed
R7847 T9506 T9514 mark that,was
R7848 T9507 T9509 det the,activity
R7849 T9508 T9509 amod transcriptional,activity
R7850 T9509 T9514 nsubj activity,was
R7851 T9510 T9509 prep of,activity
R7852 T9511 T9513 det the,promoter
R7853 T9512 T9513 compound A3G,promoter
R7854 T9513 T9510 pobj promoter,of
R7855 T9514 T9517 auxpass was,altered
R7856 T9515 T9517 neg not,altered
R7857 T9516 T9517 advmod significantly,altered
R7858 T9517 T9505 ccomp altered,showed
R7859 T9518 T9517 prep in,altered
R7860 T9519 T9520 det the,presence
R7861 T9520 T9518 pobj presence,in
R7862 T9521 T9520 prep of,presence
R7863 T9522 T9521 pobj Vif,of
R7864 T9523 T9522 punct ",",Vif
R7865 T9524 T9522 conj Tat,Vif
R7866 T9525 T9524 cc or,Tat
R7867 T9526 T9524 conj HIV-1NL4-3,Tat
R7868 T9527 T9529 punct (,4A
R7869 T9528 T9529 compound Figure,4A
R7870 T9529 T9526 appos 4A,HIV-1NL4-3
R7871 T9530 T9529 punct ),4A
R7872 T9531 T9517 punct ",",altered
R7873 T9532 T9517 advcl suggesting,altered
R7874 T9533 T9537 mark that,modulating
R7875 T9534 T9537 nsubj HIV-1,modulating
R7876 T9535 T9537 aux is,modulating
R7877 T9536 T9537 neg not,modulating
R7878 T9537 T9532 ccomp modulating,suggesting
R7879 T9538 T9539 compound A3G,expression
R7880 T9539 T9537 dobj expression,modulating
R7881 T9540 T9539 prep on,expression
R7882 T9541 T9543 det the,level
R7883 T9542 T9543 amod transcriptional,level
R7884 T9543 T9540 pobj level,on
R7885 T9544 T9505 punct .,showed
R7886 T9545 T9548 nsubjpass It,shown
R7887 T9546 T9548 aux has,shown
R7888 T9547 T9548 auxpass been,shown
R7889 T9548 T9548 ROOT shown,shown
R7890 T9549 T9559 mark that,increased
R7891 T9550 T9551 det the,amount
R7892 T9551 T9559 nsubjpass amount,increased
R7893 T9552 T9551 prep of,amount
R7894 T9553 T9554 compound A3G,mRNA
R7895 T9554 T9552 pobj mRNA,of
R7896 T9555 T9554 prep in,mRNA
R7897 T9556 T9557 compound T,cells
R7898 T9557 T9555 pobj cells,in
R7899 T9558 T9559 auxpass is,increased
R7900 T9559 T9548 ccomp increased,shown
R7901 T9560 T9559 prep in,increased
R7902 T9561 T9560 pobj response,in
R7903 T9562 T9561 prep to,response
R7904 T9563 T9564 amod mitogenic,stimulation
R7905 T9564 T9562 pobj stimulation,to
R7906 T9565 T9561 prep with,response
R7907 T9566 T9567 compound phorbol,ester
R7908 T9567 T9565 pobj ester,with
R7909 T9568 T9567 punct (,ester
R7910 T9569 T9567 appos 46,ester
R7911 T9570 T9567 appos 48,ester
R7912 T9571 T9567 punct ),ester
R7913 T9572 T9548 punct .,shown
R7914 T9573 T9579 prep In,described
R7915 T9574 T9573 pobj addition,In
R7916 T9575 T9579 punct ",",described
R7917 T9576 T9579 nsubjpass interferons,described
R7918 T9577 T9579 aux have,described
R7919 T9578 T9579 auxpass been,described
R7920 T9579 T9579 ROOT described,described
R7921 T9580 T9581 aux to,upregulate
R7922 T9581 T9579 xcomp upregulate,described
R7923 T9582 T9583 compound A3G,expression
R7924 T9583 T9581 dobj expression,upregulate
R7925 T9584 T9581 prep in,upregulate
R7926 T9585 T9584 pobj hepatocytes,in
R7927 T9586 T9585 cc and,hepatocytes
R7928 T9587 T9585 conj macrophages,hepatocytes
R7929 T9588 T9587 punct (,macrophages
R7930 T9589 T9587 appos "46,48",macrophages
R7931 T9590 T9587 punct ),macrophages
R7932 T9591 T9579 punct .,described
R7933 T9592 T9593 aux To,investigate
R7934 T9593 T9607 advcl investigate,transfected
R7935 T9594 T9597 mark whether,interfere
R7936 T9595 T9596 det these,stimuli
R7937 T9596 T9597 nsubj stimuli,interfere
R7938 T9597 T9593 ccomp interfere,investigate
R7939 T9598 T9597 prep with,interfere
R7940 T9599 T9601 nummod A3G,activity
R7941 T9600 T9601 compound promoter,activity
R7942 T9601 T9598 pobj activity,with
R7943 T9602 T9601 prep in,activity
R7944 T9603 T9604 compound T,cells
R7945 T9604 T9602 pobj cells,in
R7946 T9605 T9607 punct ",",transfected
R7947 T9606 T9607 nsubj we,transfected
R8015 T9674 T9673 pobj TPA,of
R8016 T9675 T9676 auxpass was,confirmed
R8017 T9676 T9639 advcl confirmed,showed
R8018 T9677 T9676 agent by,confirmed
R8019 T9678 T9677 pobj induction,by
R8020 T9679 T9678 prep of,induction
R8021 T9680 T9683 det the,reporter
R8022 T9681 T9683 nmod SV40,reporter
R8023 T9682 T9683 compound promoter-containing,reporter
R8024 T9683 T9687 nmod reporter,data
R8025 T9684 T9685 amod plasmid,pGL3-Control
R8026 T9685 T9687 nmod pGL3-Control,data
R8062 T9738 T9740 det a,plasmid
R8063 T9739 T9740 compound control,plasmid
R8064 T9740 T9760 nsubj plasmid,was
R8065 T9741 T9740 punct (,plasmid
R8066 T9742 T9740 appos pGL2-CVX,plasmid
R8067 T9743 T9740 punct ),plasmid
R8068 T9744 T9740 acl containing,plasmid
R8069 T9745 T9747 nummod two,GAS
R8070 T9746 T9747 compound IFN-responsive,GAS
R8071 T9747 T9744 dobj GAS,containing
R8072 T9748 T9747 punct (,GAS
R8073 T9749 T9750 nsubj gamma,activated
R8074 T9750 T9747 acl activated,GAS
R8075 T9751 T9750 npadvmod sequence,activated
R8076 T9752 T9747 punct ),GAS
R8077 T9753 T9740 conj elements,plasmid
R8078 T9754 T9753 advmod upstream,elements
R8079 T9755 T9753 prep of,elements
R8080 T9756 T9759 det the,gene
R8081 T9757 T9759 compound luciferase,gene
R8082 T9758 T9759 compound reporter,gene
R8083 T9759 T9755 pobj gene,of
R8084 T9760 T9762 auxpass was,induced
R8085 T9761 T9762 advmod only,induced
R8086 T9762 T9762 ROOT induced,induced
R8087 T9763 T9762 agent by,induced
R8088 T9764 T9763 pobj IFN-α,by
R8089 T9765 T9762 prep in,induced
R8090 T9766 T9767 det these,cells
R8091 T9767 T9765 pobj cells,in
R8092 T9768 T9770 punct (,4C
R8093 T9769 T9770 compound Figure,4C
R8094 T9770 T9762 dep 4C,induced
R8095 T9771 T9770 punct ),4C
R8096 T9772 T9762 punct .,induced
R8097 T9773 T9776 mark Since,describe
R8098 T9774 T9775 nummod two,reports
R8099 T9775 T9776 nsubj reports,describe
R8100 T9776 T9789 advcl describe,performed
R8101 T9777 T9778 compound A3G,upregulation
R8102 T9778 T9776 dobj upregulation,describe
R8103 T9779 T9776 prep by,describe
R8104 T9780 T9779 pobj interferons,by
R8105 T9781 T9776 prep in,describe
R8106 T9782 T9781 pobj hepatocytes,in
R8107 T9783 T9782 punct (,hepatocytes
R8108 T9784 T9782 appos "47,48",hepatocytes
R8109 T9785 T9782 punct ),hepatocytes
R8110 T9786 T9789 punct ",",performed
R8111 T9787 T9789 nsubj we,performed
R8112 T9788 T9789 advmod additionally,performed
R8113 T9789 T9789 ROOT performed,performed
R8114 T9790 T9791 det the,experiment
R8115 T9791 T9789 dobj experiment,performed
R8116 T9792 T9789 prep in,performed
R8117 T9793 T9796 det the,line
R8118 T9794 T9796 amod hepatic,line
R8119 T9795 T9796 compound cell,line
R8120 T9796 T9792 pobj line,in
R8121 T9797 T9796 appos HepG2,line
R8122 T9798 T9789 punct .,performed
R8123 T9799 T9806 prep In,observed
R8124 T9800 T9799 pobj line,In
R8125 T9801 T9800 prep with,line
R8126 T9802 T9803 det these,publications
R8127 T9803 T9801 pobj publications,with
R8128 T9804 T9806 punct ",",observed
R8129 T9805 T9806 nsubj we,observed
R8130 T9806 T9806 ROOT observed,observed
R8131 T9807 T9808 det an,induction
R8132 T9808 T9806 dobj induction,observed
R8133 T9809 T9808 prep of,induction
R8134 T9810 T9812 det the,promoter
R8135 T9811 T9812 compound A3G,promoter
R8136 T9812 T9809 pobj promoter,of
R8137 T9813 T9808 prep by,induction
R8138 T9814 T9815 advmod approximately,2-fold
R8139 T9815 T9813 pobj 2-fold,by
R8140 T9816 T9808 prep after,induction
R8141 T9817 T9820 amod IFN-α,stimulation
R8142 T9818 T9817 cc or,IFN-α
R8143 T9819 T9817 conj IFN-γ,IFN-α
R8144 T9820 T9816 pobj stimulation,after
R8145 T9821 T9822 punct (,Figure
R8146 T9822 T9820 appos Figure,stimulation
R8147 T9823 T9822 nummod 4D,Figure
R8148 T9824 T9808 punct ),induction
R8149 T9825 T9806 prep with,observed
R8150 T9826 T9827 nsubj IFN-γ,being
R8151 T9827 T9825 pcomp being,with
R8152 T9828 T9829 advmod slightly,more
R8153 T9829 T9830 advmod more,potent
R8154 T9830 T9827 acomp potent,being
R8155 T9831 T9806 punct .,observed
R8156 T9832 T9843 prep For,observed
R8157 T9833 T9835 det both,types
R8158 T9834 T9835 compound interferon,types
R8159 T9835 T9832 pobj types,For
R8160 T9836 T9843 punct ",",observed
R8161 T9837 T9843 nsubjpass induction,observed
R8162 T9838 T9837 prep of,induction
R8163 T9839 T9841 compound A3G,activity
R8164 T9840 T9841 compound promoter,activity
R8165 T9841 T9838 pobj activity,of
R8166 T9842 T9843 auxpass was,observed
R8167 T9843 T9843 ROOT observed,observed
R8168 T9844 T9843 prep for,observed
R8169 T9845 T9846 det all,deletion
R8170 T9846 T9844 pobj deletion,for
R8171 T9847 T9843 conj constructs,observed
R8172 T9848 T9847 prep except,constructs
R8173 T9849 T9848 prep for,except
R8174 T9850 T9853 det the,fragment
R8175 T9851 T9853 nummod 60,fragment
R8176 T9852 T9853 compound bp,fragment
R8177 T9853 T9849 pobj fragment,for
R8178 T9854 T9847 punct ",",constructs
R8179 T9855 T9847 advcl indicating,constructs
R8180 T9856 T9861 mark that,located
R8181 T9857 T9859 det the,region
R8182 T9858 T9859 amod responsible,region
R8183 T9859 T9861 nsubjpass region,located
R8184 T9860 T9861 auxpass is,located
R8185 T9861 T9855 ccomp located,indicating
R8186 T9862 T9861 prep within,located
R8187 T9863 T9866 det the,present
R8188 T9864 T9865 nummod 60,nt
R8189 T9865 T9866 compound nt,present
R8190 T9866 T9862 pobj present,within
R8191 T9867 T9866 prep in,present
R8192 T9868 T9870 det the,bp
R8193 T9869 T9870 nummod 120,bp
R8194 T9870 T9867 pobj bp,in
R8195 T9871 T9861 punct ",",located
R8196 T9872 T9861 cc but,located
R8197 T9873 T9874 neg not,in
R8198 T9874 T9861 conj in,located
R8199 T9875 T9878 det the,fragment
R8200 T9876 T9878 nummod 60,fragment
R8201 T9877 T9878 compound bp,fragment
R8202 T9878 T9874 pobj fragment,in
R8203 T9879 T9843 punct .,observed
R15891 T19681 T19683 nummod A3G,activities
R15892 T19682 T19683 compound promoter,activities
R15893 T19683 T19683 ROOT activities,activities
R15894 T19684 T19683 prep after,activities
R15895 T19685 T19684 pobj coexpression,after
R15896 T19686 T19685 prep of,coexpression
R15897 T19687 T19688 compound HIV-1,proteins
R15898 T19688 T19686 pobj proteins,of
R15899 T19689 T19688 cc or,proteins
R15900 T19690 T19683 appos treatment,activities
R15901 T19691 T19690 prep with,treatment
R15902 T19692 T19691 pobj TPA,with
R15903 T19693 T19692 cc or,TPA
R15904 T19694 T19692 conj interferons,TPA
R15905 T19695 T19683 punct .,activities
R15906 T19696 T19704 punct (,cotransfected
R15907 T19697 T19702 det A,cells
R15908 T19698 T19699 punct ),A3
R15909 T19699 T19702 nmod A3,cells
R15910 T19700 T19702 nummod .01,cells
R15911 T19701 T19702 compound T,cells
R15912 T19702 T19704 nsubjpass cells,cotransfected
R15913 T19703 T19704 auxpass were,cotransfected
R15914 T19704 T19704 ROOT cotransfected,cotransfected
R15915 T19705 T19704 prep with,cotransfected
R15916 T19706 T19708 amod pGL3-Basic,plasmid
R15917 T19707 T19708 compound reporter,plasmid
R15918 T19708 T19705 pobj plasmid,with
R15919 T19709 T19708 acl containing,plasmid
R15920 T19710 T19714 det the,promoter
R15921 T19711 T19714 nummod 1025,promoter
R15922 T19712 T19714 nmod bp,promoter
R15923 T19713 T19712 nummod A3G,bp
R15924 T19714 T19709 dobj promoter,containing
R15925 T19715 T19714 cc and,promoter
R15926 T19716 T19717 nummod 1,µg
R15927 T19717 T19714 conj µg,promoter
R15928 T19718 T19717 prep of,µg
R15929 T19719 T19721 compound Vif,plasmid
R15930 T19720 T19721 compound expression,plasmid
R15931 T19721 T19718 pobj plasmid,of
R15932 T19722 T19721 punct ",",plasmid
R15933 T19723 T19724 nummod 1,µg
R15934 T19724 T19727 compound µg,plasmid
R15935 T19725 T19727 compound Tat,plasmid
R15936 T19726 T19727 compound expression,plasmid
R15937 T19727 T19721 conj plasmid,plasmid
R15938 T19728 T19727 cc or,plasmid
R15939 T19729 T19727 conj increasing,plasmid
R15940 T19730 T19729 dobj amounts,increasing
R15941 T19731 T19730 prep of,amounts
R15942 T19732 T19731 pobj HIV-1NL4-3,of
R15943 T19733 T19732 punct (,HIV-1NL4-3
R15944 T19734 T19732 appos 0.1,HIV-1NL4-3
R15945 T19735 T19732 punct ",",HIV-1NL4-3
R15946 T19736 T19732 nummod 0.5,HIV-1NL4-3
R15947 T19737 T19730 cc and,amounts
R15948 T19738 T19739 nummod 1,µg
R15949 T19739 T19730 conj µg,amounts
R15950 T19740 T19739 punct ),µg
R15951 T19741 T19704 punct .,cotransfected
R15952 T19742 T19748 prep After,harvested
R15953 T19743 T19744 nummod 48,h
R15954 T19744 T19742 pobj h,After
R15955 T19745 T19748 punct ",",harvested
R15956 T19746 T19748 nsubjpass cells,harvested
R15957 T19747 T19748 auxpass were,harvested
R15958 T19748 T19748 ROOT harvested,harvested
R15959 T19749 T19748 prep for,harvested
R15960 T19750 T19751 compound luciferase,assay
R15961 T19751 T19749 pobj assay,for
R15962 T19752 T19748 punct .,harvested
R15963 T19753 T19757 advmod Firefly,normalized
R15964 T19754 T19755 amod luciferase,activities
R15965 T19755 T19757 nsubjpass activities,normalized
R15966 T19756 T19757 auxpass were,normalized
R15967 T19757 T19757 ROOT normalized,normalized
R15968 T19758 T19757 prep to,normalized
R15969 T19759 T19762 amod coexpressed,activities
R15970 T19760 T19762 amod renilla,activities
R15971 T19761 T19762 compound luciferase,activities
R15972 T19762 T19758 pobj activities,to
R15973 T19763 T19757 punct .,normalized
R15974 T19764 T19767 punct (,A3
R15975 T19765 T19767 nmod B,A3
R15976 T19766 T19767 punct ),A3
R15977 T19767 T19773 nsubjpass A3,transfected
R15978 T19768 T19770 nummod .01,cells
R15979 T19769 T19770 compound T,cells
R15980 T19770 T19773 nsubjpass cells,transfected
R15981 T19771 T19773 auxpass were,transfected
R15982 T19772 T19773 advmod transiently,transfected
R15983 T19773 T19773 ROOT transfected,transfected
R15984 T19774 T19773 prep with,transfected
R15985 T19775 T19777 amod pGL3-Basic,plasmid
R15986 T19776 T19777 compound reporter,plasmid
R15987 T19777 T19774 pobj plasmid,with
R15988 T19778 T19777 acl containing,plasmid
R15989 T19779 T19783 det the,promoter
R15990 T19780 T19783 nummod 1025,promoter
R15991 T19781 T19783 nmod bp,promoter
R15992 T19782 T19783 det A3G,promoter
R15993 T19783 T19778 dobj promoter,containing
R15994 T19784 T19774 cc or,with
R15995 T19785 T19774 conj with,with
R15996 T19786 T19787 amod empty,vector
R15997 T19787 T19785 pobj vector,with
R15998 T19788 T19773 punct .,transfected
R15999 T19789 T19790 nummod Fifteen,hour
R16000 T19790 T19791 npadvmod hour,before
R16001 T19791 T19804 prep before,stimulated
R16002 T19792 T19791 pcomp harvesting,before
R16003 T19793 T19792 prep for,harvesting
R16004 T19794 T19795 compound luciferase,assay
R16005 T19795 T19793 pobj assay,for
R16006 T19796 T19804 punct ",",stimulated
R16007 T19797 T19798 det a,subset
R16008 T19798 T19804 nsubjpass subset,stimulated
R16009 T19799 T19798 prep of,subset
R16010 T19800 T19802 det the,culture
R16011 T19801 T19802 compound cell,culture
R16012 T19802 T19799 pobj culture,of
R16013 T19803 T19804 auxpass was,stimulated
R16014 T19804 T19804 ROOT stimulated,stimulated
R16015 T19805 T19804 prep with,stimulated
R16016 T19806 T19807 nummod 20,ng/ml
R16017 T19807 T19805 pobj ng/ml,with
R16018 T19808 T19807 appos TPA,ng/ml
R16019 T19809 T19804 punct .,stimulated
R16020 T19810 T19811 amod Forty-eight,hour
R16021 T19811 T19812 npadvmod hour,after
R16022 T19812 T19818 prep after,performed
R16023 T19813 T19812 pobj transfection,after
R16024 T19814 T19818 punct ",",performed
R16025 T19815 T19816 compound luciferase,assay
R16026 T19816 T19818 nsubjpass assay,performed
R16027 T19817 T19818 auxpass was,performed
R16028 T19818 T19818 ROOT performed,performed
R16029 T19819 T19818 punct .,performed
R16030 T19820 T19824 advmod Firefly,normalized
R16031 T19821 T19822 amod luciferase,activities
R16032 T19822 T19824 nsubjpass activities,normalized
R16033 T19823 T19824 auxpass were,normalized
R16034 T19824 T19843 nsubjpass normalized,set
R16035 T19825 T19824 prep to,normalized
R16036 T19826 T19829 amod coexpressed,activities
R16037 T19827 T19829 compound renilla,activities
R16038 T19828 T19829 compound luciferase,activities
R16039 T19829 T19825 pobj activities,to
R16040 T19830 T19829 cc and,activities
R16041 T19831 T19832 det the,values
R16042 T19832 T19829 conj values,activities
R16043 T19833 T19832 prep for,values
R16044 T19834 T19836 det the,vectors
R16045 T19835 T19836 amod empty,vectors
R16046 T19836 T19833 pobj vectors,for
R16047 T19837 T19836 punct (,vectors
R16048 T19838 T19836 amod untreated,vectors
R16049 T19839 T19838 cc and,untreated
R16050 T19840 T19838 conj TPA-stimulated,untreated
R16051 T19841 T19836 punct ),vectors
R16052 T19842 T19843 auxpass were,set
R16053 T19843 T19843 ROOT set,set
R16054 T19844 T19843 prep as,set
R16055 T19845 T19844 pobj 1,as
R16056 T19846 T19843 punct .,set
R16057 T19847 T19848 punct (,C
R16058 T19848 T19848 ROOT C,C
R16059 T19849 T19848 punct ),C
R16060 T19850 T19853 nummod A3,cells
R16061 T19851 T19853 nummod .01,cells
R16062 T19852 T19853 compound T,cells
R16063 T19853 T19856 nsubjpass cells,transfected
R16064 T19854 T19856 auxpass were,transfected
R16065 T19855 T19856 advmod transiently,transfected
R16066 T19856 T19856 ROOT transfected,transfected
R16067 T19857 T19856 prep with,transfected
R16068 T19858 T19861 det the,constructs
R16069 T19859 T19860 compound A3G,promoter
R16070 T19860 T19861 nsubj promoter,constructs
R16071 T19861 T19857 pobj constructs,with
R16072 T19862 T19857 cc or,with
R16073 T19863 T19857 conj with,with
R16074 T19864 T19867 det the,plasmid
R16075 T19865 T19867 amod interferon-responsive,plasmid
R16076 T19866 T19867 compound reporter,plasmid
R16077 T19867 T19868 compound plasmid,pGL2-CVX
R16078 T19868 T19863 pobj pGL2-CVX,with
R16079 T19869 T19870 punct (,GAS
R16080 T19870 T19868 appos GAS,pGL2-CVX
R16081 T19871 T19856 punct ),transfected
R16082 T19872 T19856 punct .,transfected
R16083 T19873 T19874 nummod Fifteen,hour
R16084 T19874 T19875 npadvmod hour,before
R16085 T19875 T19888 prep before,stimulated
R16086 T19876 T19875 pcomp harvesting,before
R16087 T19877 T19876 prep for,harvesting
R16088 T19878 T19879 compound luciferase,assay
R16089 T19879 T19877 pobj assay,for
R16090 T19880 T19888 punct ",",stimulated
R16091 T19881 T19882 det a,subset
R16092 T19882 T19888 nsubjpass subset,stimulated
R16093 T19883 T19882 prep of,subset
R16094 T19884 T19886 det the,culture
R16095 T19885 T19886 compound cell,culture
R16096 T19886 T19883 pobj culture,of
R16097 T19887 T19888 auxpass was,stimulated
R16098 T19888 T19888 ROOT stimulated,stimulated
R16099 T19889 T19888 prep with,stimulated
R16100 T19890 T19891 nummod 30,ng/ml
R16101 T19891 T19892 compound ng/ml,IFN-α
R16102 T19892 T19889 pobj IFN-α,with
R16103 T19893 T19892 cc or,IFN-α
R16104 T19894 T19892 conj IFN-γ,IFN-α
R16105 T19895 T19888 punct .,stimulated
R16106 T19896 T19897 amod Forty-eight,hour
R16107 T19897 T19898 npadvmod hour,after
R16108 T19898 T19904 prep after,performed
R16109 T19899 T19898 pobj transfection,after
R16110 T19900 T19904 punct ",",performed
R16111 T19901 T19902 compound luciferase,assay
R16112 T19902 T19904 nsubjpass assay,performed
R16113 T19903 T19904 auxpass was,performed
R16114 T19904 T19904 ROOT performed,performed
R16115 T19905 T19904 punct .,performed
R16116 T19906 T19910 advmod Firefly,normalized
R16117 T19907 T19908 amod luciferase,activities
R16118 T19908 T19910 nsubjpass activities,normalized
R16119 T19909 T19910 auxpass were,normalized
R16120 T19910 T19910 ROOT normalized,normalized
R16121 T19911 T19910 prep to,normalized
R16122 T19912 T19915 amod coexpressed,activities
R16123 T19913 T19915 compound renilla,activities
R16124 T19914 T19915 compound luciferase,activities
R16125 T19915 T19911 pobj activities,to
R16126 T19916 T19910 punct .,normalized
R16127 T19917 T19918 punct (,D
R16128 T19918 T19918 ROOT D,D
R16129 T19919 T19918 punct ),D
R16130 T19920 T19921 amod HepG2,cells
R16131 T19921 T19923 nsubjpass cells,used
R16132 T19922 T19923 auxpass were,used
R16133 T19923 T19923 ROOT used,used
R16134 T19924 T19923 prep for,used
R16135 T19925 T19924 pobj transfection,for
R16136 T19926 T19923 punct .,used
R16137 T19927 T19928 det The,experiment
R16138 T19928 T19930 nsubjpass experiment,performed
R16139 T19929 T19930 auxpass was,performed
R16140 T19930 T19930 ROOT performed,performed
R16141 T19931 T19932 mark as,described
R16142 T19932 T19930 advcl described,performed
R16143 T19933 T19932 prep in,described
R16144 T19934 T19935 punct (,C
R16145 T19935 T19933 pobj C,in
R16146 T19936 T19930 punct ),performed
R16147 T19937 T19930 punct .,performed
R16148 T19938 T19939 amod Mean,values
R16149 T19939 T19951 nsubjpass values,shown
R16150 T19940 T19942 punct (,SD
R16151 T19941 T19942 nummod ±,SD
R16152 T19942 T19939 appos SD,values
R16153 T19943 T19942 punct ),SD
R16154 T19944 T19942 prep of,SD
R16155 T19945 T19946 compound representative,experiments
R16156 T19946 T19944 pobj experiments,of
R16157 T19947 T19946 acl performed,experiments
R16158 T19948 T19947 prep in,performed
R16159 T19949 T19948 pobj triplicate,in
R16160 T19950 T19951 auxpass are,shown
R16161 T19951 T19951 ROOT shown,shown
R16162 T19952 T19951 punct .,shown
R7948 T9607 T9607 ROOT transfected,transfected
R7949 T9608 T9607 dobj A3,transfected
R7950 T9609 T9611 nummod .01,cells
R7951 T9610 T9611 compound T,cells
R7952 T9611 T9608 dobj cells,A3
R7953 T9612 T9611 prep with,cells
R7954 T9613 T9616 det the,promoter
R7955 T9614 T9616 nummod 1025,promoter
R7956 T9615 T9616 compound bp,promoter
R7957 T9616 T9612 pobj promoter,with
R7958 T9617 T9616 cc or,promoter
R7959 T9618 T9623 det the,vector
R7960 T9619 T9623 amod empty,vector
R7961 T9620 T9623 nmod vector,vector
R7962 T9621 T9623 amod pGL3-Basic,vector
R7963 T9622 T9621 punct (,pGL3-Basic
R7964 T9623 T9616 conj vector,promoter
R7965 T9624 T9611 punct ),cells
R7966 T9625 T9607 cc and,transfected
R7967 T9626 T9607 conj treated,transfected
R7968 T9627 T9628 det the,cells
R7969 T9628 T9626 dobj cells,treated
R7970 T9629 T9626 prep with,treated
R7971 T9630 T9631 compound phorbol,ester
R7972 T9631 T9629 pobj ester,with
R7973 T9632 T9633 punct (,TPA
R7974 T9633 T9631 appos TPA,ester
R7975 T9634 T9631 punct ),ester
R7976 T9635 T9607 punct .,transfected
R7977 T9636 T9638 det The,assay
R7978 T9637 T9638 compound luciferase,assay
R7979 T9638 T9639 nsubj assay,showed
R7980 T9639 T9639 ROOT showed,showed
R7981 T9640 T9657 mark that,was
R7982 T9641 T9643 det the,15-fold
R7983 T9642 T9643 amod ∼,15-fold
R7984 T9643 T9644 nsubj 15-fold,increased
R7985 T9644 T9646 amod increased,activity
R7986 T9645 T9646 amod transcriptional,activity
R7987 T9646 T9657 nsubj activity,was
R7988 T9647 T9646 prep of,activity
R7989 T9648 T9651 det the,promoter
R7990 T9649 T9651 nummod 1025,promoter
R7991 T9650 T9651 compound bp,promoter
R7992 T9651 T9647 pobj promoter,of
R7993 T9652 T9651 amod relative,promoter
R7994 T9653 T9652 prep to,relative
R7995 T9654 T9656 det the,vector
R7996 T9655 T9656 amod empty,vector
R7997 T9656 T9653 pobj vector,to
R7998 T9657 T9660 auxpass was,enhanced
R7999 T9658 T9660 neg not,enhanced
R8000 T9659 T9660 advmod further,enhanced
R8001 T9660 T9639 ccomp enhanced,showed
R8002 T9661 T9660 agent by,enhanced
R8003 T9662 T9663 compound TPA,treatment
R8004 T9663 T9661 pobj treatment,by
R8005 T9664 T9666 punct (,4B
R8006 T9665 T9666 nmod Figure,4B
R8007 T9666 T9663 appos 4B,treatment
R8008 T9667 T9660 punct ),enhanced
R8009 T9668 T9639 punct ",",showed
R8010 T9669 T9676 mark although,confirmed
R8011 T9670 T9672 det the,activity
R8012 T9671 T9672 amod functional,activity
R8013 T9672 T9676 nsubjpass activity,confirmed
R8014 T9673 T9672 prep of,activity
R8027 T9686 T9687 punct (,data
R8028 T9687 T9679 pobj data,of
R8029 T9688 T9689 neg not,shown
R8030 T9689 T9687 acl shown,data
R8031 T9690 T9687 punct ),data
R8032 T9691 T9639 punct .,showed
R8033 T9692 T9700 advmod Similarly,transfected
R8034 T9693 T9700 punct ",",transfected
R8035 T9694 T9700 nsubj treatment,transfected
R8036 T9695 T9694 prep of,treatment
R8037 T9696 T9699 nummod A3,cells
R8038 T9697 T9699 nummod .01,cells
R8039 T9698 T9699 compound T,cells
R8040 T9699 T9695 pobj cells,of
R8041 T9700 T9700 ROOT transfected,transfected
R8042 T9701 T9700 prep with,transfected
R8043 T9702 T9705 det the,deletion
R8044 T9703 T9704 compound A3G,promoter
R8045 T9704 T9705 compound promoter,deletion
R8046 T9705 T9706 compound deletion,constructs
R8047 T9706 T9701 pobj constructs,with
R8048 T9707 T9706 prep with,constructs
R8049 T9708 T9728 nsubj IFN-α,showed
R8050 T9726 T9708 cc or,IFN-α
R8051 T9727 T9708 conj IFN-γ,IFN-α
R8052 T9728 T9700 conj showed,transfected
R8053 T9729 T9730 det no,effect
R8054 T9730 T9728 dobj effect,showed
R8055 T9731 T9733 punct (,4C
R8056 T9732 T9733 nmod Figure,4C
R8057 T9733 T9730 appos 4C,effect
R8058 T9734 T9733 punct ),4C
R8059 T9735 T9728 punct .,showed
R8060 T9736 T9760 advmod Interestingly,was
R8061 T9737 T9760 punct ",",was

sentences

Id Subject Object Predicate Lexical cue
T8841 0-44 Sentence denotes The A3G promoter is not inducible in T cells
T8842 45-154 Sentence denotes According to the current knowledge, APOBEC3G plays a role in the innate defence against pathogens like HIV-1.
T8843 155-262 Sentence denotes The latter has evolved a mechanism to counteract A3G activity by expressing the regulatory protein Vif (4).
T8844 263-378 Sentence denotes Vif induces proteasomal degradation of A3G and additionally inhibits A3G activity by further mechanisms (8, 37–43).
T8845 379-619 Sentence denotes To investigate whether the overexpression of HIV-1 proteins also influences A3G promoter activity, we either expressed HIV-1 Vif or the HIV-1 Tat protein, the latter has been shown to activate different viral and cellular promoters (44,45).
T8846 620-736 Sentence denotes In addition, increasing amounts of the plasmid pNL4-3, containing the full-length genome of HIV-1, were transfected.
T8847 737-848 Sentence denotes These constructs or the empty vector pcDNA3.1 were cotransfected with the 1025 bp construct into A3.01 T cells.
T8848 849-1097 Sentence denotes Luciferase assays showed that the transcriptional activity of the A3G promoter was not significantly altered in the presence of Vif, Tat or HIV-1NL4-3 (Figure 4A), suggesting that HIV-1 is not modulating A3G expression on the transcriptional level.
T8849 2690-2824 Sentence denotes It has been shown that the amount of A3G mRNA in T cells is increased in response to mitogenic stimulation with phorbol ester (46–48).
T8850 2825-2938 Sentence denotes In addition, interferons have been described to upregulate A3G expression in hepatocytes and macrophages (46,48).
T8851 2939-3167 Sentence denotes To investigate whether these stimuli interfere with A3G promoter activity in T cells, we transfected A3.01 T cells with the 1025 bp promoter or the empty vector pGL3-Basic (vector) and treated the cells with phorbol ester (TPA).
T8852 3168-3503 Sentence denotes The luciferase assay showed that the ∼15-fold increased transcriptional activity of the 1025 bp promoter relative to the empty vector was not further enhanced by TPA treatment (Figure 4B), although the functional activity of TPA was confirmed by induction of the SV40 promoter-containing reporter plasmid pGL3-Control (data not shown).
T8853 3504-3645 Sentence denotes Similarly, treatment of A3.01 T cells transfected with the A3G promoter deletion constructs with IFN-α or IFN-γ showed no effect (Figure 4C).
T8854 3646-3854 Sentence denotes Interestingly, a control plasmid (pGL2-CVX) containing two IFN-responsive GAS (gamma activated sequence) elements upstream of the luciferase reporter gene was only induced by IFN-α in these cells (Figure 4C).
T8855 3855-4010 Sentence denotes Since two reports describe A3G upregulation by interferons in hepatocytes (47,48), we additionally performed the experiment in the hepatic cell line HepG2.
T8856 4011-4196 Sentence denotes In line with these publications, we observed an induction of the A3G promoter by approximately 2-fold after IFN-α or IFN-γ stimulation (Figure 4D) with IFN-γ being slightly more potent.
T8857 4197-4451 Sentence denotes For both interferon types, induction of A3G promoter activity was observed for all deletion constructs except for the 60 bp fragment, indicating that the responsible region is located within the 60 nt present in the 120 bp, but not in the 60 bp fragment.
T19364 1108-1433 Sentence denotes A3G promoter activities after coexpression of HIV-1 proteins or treatment with TPA or interferons. (A) A3.01 T cells were cotransfected with pGL3-Basic reporter plasmid containing the 1025 bp A3G promoter and 1 µg of Vif expression plasmid, 1 µg Tat expression plasmid or increasing amounts of HIV-1NL4-3 (0.1, 0.5 and 1 µg).
T19365 1434-1488 Sentence denotes After 48 h, cells were harvested for luciferase assay.
T19366 1489-1718 Sentence denotes Firefly luciferase activities were normalized to coexpressed renilla luciferase activities. (B) A3.01 T cells were transiently transfected with pGL3-Basic reporter plasmid containing the 1025 bp A3G promoter or with empty vector.
T19367 1719-1834 Sentence denotes Fifteen hour before harvesting for luciferase assay, a subset of the cell culture was stimulated with 20 ng/ml TPA.
T19368 1835-1903 Sentence denotes Forty-eight hour after transfection, luciferase assay was performed.
T19369 1904-2224 Sentence denotes Firefly luciferase activities were normalized to coexpressed renilla luciferase activities and the values for the empty vectors (untreated and TPA-stimulated) were set as 1. (C) A3.01 T cells were transiently transfected with the A3G promoter constructs or with the interferon-responsive reporter plasmid pGL2-CVX (GAS).
T19370 2225-2351 Sentence denotes Fifteen hour before harvesting for luciferase assay, a subset of the cell culture was stimulated with 30 ng/ml IFN-α or IFN-γ.
T19371 2352-2420 Sentence denotes Forty-eight hour after transfection, luciferase assay was performed.
T19372 2421-2556 Sentence denotes Firefly luciferase activities were normalized to coexpressed renilla luciferase activities. (D) HepG2 cells were used for transfection.
T19373 2557-2606 Sentence denotes The experiment was performed as described in (C).
T19374 2607-2689 Sentence denotes Mean values (±SD) of representative experiments performed in triplicate are shown.
T168 0-44 Sentence denotes The A3G promoter is not inducible in T cells
T169 45-154 Sentence denotes According to the current knowledge, APOBEC3G plays a role in the innate defence against pathogens like HIV-1.
T170 155-262 Sentence denotes The latter has evolved a mechanism to counteract A3G activity by expressing the regulatory protein Vif (4).
T171 263-378 Sentence denotes Vif induces proteasomal degradation of A3G and additionally inhibits A3G activity by further mechanisms (8, 37–43).
T172 379-619 Sentence denotes To investigate whether the overexpression of HIV-1 proteins also influences A3G promoter activity, we either expressed HIV-1 Vif or the HIV-1 Tat protein, the latter has been shown to activate different viral and cellular promoters (44,45).
T173 620-736 Sentence denotes In addition, increasing amounts of the plasmid pNL4-3, containing the full-length genome of HIV-1, were transfected.
T174 737-848 Sentence denotes These constructs or the empty vector pcDNA3.1 were cotransfected with the 1025 bp construct into A3.01 T cells.
T175 849-1097 Sentence denotes Luciferase assays showed that the transcriptional activity of the A3G promoter was not significantly altered in the presence of Vif, Tat or HIV-1NL4-3 (Figure 4A), suggesting that HIV-1 is not modulating A3G expression on the transcriptional level.
T176 1098-1107 Sentence denotes Figure 4.
T177 1108-1433 Sentence denotes A3G promoter activities after coexpression of HIV-1 proteins or treatment with TPA or interferons. (A) A3.01 T cells were cotransfected with pGL3-Basic reporter plasmid containing the 1025 bp A3G promoter and 1 µg of Vif expression plasmid, 1 µg Tat expression plasmid or increasing amounts of HIV-1NL4-3 (0.1, 0.5 and 1 µg).
T178 1434-1488 Sentence denotes After 48 h, cells were harvested for luciferase assay.
T179 1489-1718 Sentence denotes Firefly luciferase activities were normalized to coexpressed renilla luciferase activities. (B) A3.01 T cells were transiently transfected with pGL3-Basic reporter plasmid containing the 1025 bp A3G promoter or with empty vector.
T180 1719-1834 Sentence denotes Fifteen hour before harvesting for luciferase assay, a subset of the cell culture was stimulated with 20 ng/ml TPA.
T181 1835-1903 Sentence denotes Forty-eight hour after transfection, luciferase assay was performed.
T182 1904-2224 Sentence denotes Firefly luciferase activities were normalized to coexpressed renilla luciferase activities and the values for the empty vectors (untreated and TPA-stimulated) were set as 1. (C) A3.01 T cells were transiently transfected with the A3G promoter constructs or with the interferon-responsive reporter plasmid pGL2-CVX (GAS).
T183 2225-2351 Sentence denotes Fifteen hour before harvesting for luciferase assay, a subset of the cell culture was stimulated with 30 ng/ml IFN-α or IFN-γ.
T184 2352-2420 Sentence denotes Forty-eight hour after transfection, luciferase assay was performed.
T185 2421-2556 Sentence denotes Firefly luciferase activities were normalized to coexpressed renilla luciferase activities. (D) HepG2 cells were used for transfection.
T186 2557-2606 Sentence denotes The experiment was performed as described in (C).
T187 2607-2689 Sentence denotes Mean values (±SD) of representative experiments performed in triplicate are shown.
T188 2690-2824 Sentence denotes It has been shown that the amount of A3G mRNA in T cells is increased in response to mitogenic stimulation with phorbol ester (46–48).
T189 2825-2938 Sentence denotes In addition, interferons have been described to upregulate A3G expression in hepatocytes and macrophages (46,48).
T190 2939-3167 Sentence denotes To investigate whether these stimuli interfere with A3G promoter activity in T cells, we transfected A3.01 T cells with the 1025 bp promoter or the empty vector pGL3-Basic (vector) and treated the cells with phorbol ester (TPA).
T191 3168-3503 Sentence denotes The luciferase assay showed that the ∼15-fold increased transcriptional activity of the 1025 bp promoter relative to the empty vector was not further enhanced by TPA treatment (Figure 4B), although the functional activity of TPA was confirmed by induction of the SV40 promoter-containing reporter plasmid pGL3-Control (data not shown).
T192 3504-3645 Sentence denotes Similarly, treatment of A3.01 T cells transfected with the A3G promoter deletion constructs with IFN-α or IFN-γ showed no effect (Figure 4C).
T193 3646-3854 Sentence denotes Interestingly, a control plasmid (pGL2-CVX) containing two IFN-responsive GAS (gamma activated sequence) elements upstream of the luciferase reporter gene was only induced by IFN-α in these cells (Figure 4C).
T194 3855-4010 Sentence denotes Since two reports describe A3G upregulation by interferons in hepatocytes (47,48), we additionally performed the experiment in the hepatic cell line HepG2.
T195 4011-4196 Sentence denotes In line with these publications, we observed an induction of the A3G promoter by approximately 2-fold after IFN-α or IFN-γ stimulation (Figure 4D) with IFN-γ being slightly more potent.
T196 4197-4451 Sentence denotes For both interferon types, induction of A3G promoter activity was observed for all deletion constructs except for the 60 bp fragment, indicating that the responsible region is located within the 60 nt present in the 120 bp, but not in the 60 bp fragment.

2_test

Id Subject Object Predicate Lexical cue
17517765-12167863-77155602 259-260 12167863 denotes 4
17517765-12859895-77155603 368-369 12859895 denotes 8
17517765-14528300-77155604 374-376 14528300 denotes 43
17517765-14528301-77155604 374-376 14528301 denotes 43
17517765-14614829-77155604 374-376 14614829 denotes 43
17517765-14672928-77155604 374-376 14672928 denotes 43
17517765-14564014-77155604 374-376 14564014 denotes 43
17517765-14557625-77155604 374-376 14557625 denotes 43
17517765-14527406-77155604 374-376 14527406 denotes 43
17517765-14981150-77155605 612-614 14981150 denotes 44
17517765-9045614-77155606 615-617 9045614 denotes 45
17517765-16418394-77155607 2820-2822 16418394 denotes 48
17517765-16729314-77155607 2820-2822 16729314 denotes 48
17517765-16426578-77155607 2820-2822 16426578 denotes 48
17517765-16418394-77155608 2931-2933 16418394 denotes 46
17517765-16426578-77155609 2934-2936 16426578 denotes 48
17517765-16729314-77155610 3930-3932 16729314 denotes 47
17517765-16426578-77155611 3933-3935 16426578 denotes 48

pmc-enju-pas

Id Subject Object Predicate Lexical cue
T8864 0-3 DT denotes The
T8865 4-7 NN denotes A3G
T8866 8-16 NN denotes promoter
T8867 17-19 VB denotes is
T8868 20-23 RB denotes not
T8869 24-33 JJ denotes inducible
T8870 34-36 IN denotes in
T8871 37-38 NN denotes T
T8872 39-44 NN denotes cells
T8873 45-54 VB denotes According
T8874 55-57 TO denotes to
T8875 58-61 DT denotes the
T8876 62-69 JJ denotes current
T8877 70-79 NN denotes knowledge
T8878 79-80 -COMMA- denotes ,
T8879 81-89 NN denotes APOBEC3G
T8880 90-95 VB denotes plays
T8881 96-97 DT denotes a
T8882 98-102 NN denotes role
T8883 103-105 IN denotes in
T8884 106-109 DT denotes the
T8885 110-116 JJ denotes innate
T8886 117-124 NN denotes defence
T8887 125-132 IN denotes against
T8888 133-142 NN denotes pathogens
T8889 143-147 IN denotes like
T8890 148-153 NN denotes HIV-1
T8891 155-158 DT denotes The
T8892 159-165 JJ denotes latter
T8893 166-169 VB denotes has
T8894 170-177 VB denotes evolved
T8895 178-179 DT denotes a
T8896 180-189 NN denotes mechanism
T8897 190-192 TO denotes to
T8898 193-203 VB denotes counteract
T8899 204-207 NN denotes A3G
T8900 208-216 NN denotes activity
T8901 217-219 IN denotes by
T8902 220-230 VB denotes expressing
T8903 231-234 DT denotes the
T8904 235-245 JJ denotes regulatory
T8905 246-253 NN denotes protein
T8906 254-257 NN denotes Vif
T8907 258-259 -LRB- denotes (
T8908 259-260 CD denotes 4
T8909 260-261 -RRB- denotes )
T8910 263-266 NN denotes Vif
T8911 267-274 VB denotes induces
T8912 275-286 JJ denotes proteasomal
T8913 287-298 NN denotes degradation
T8914 299-301 IN denotes of
T8915 302-305 NN denotes A3G
T8916 306-309 CC denotes and
T8917 310-322 RB denotes additionally
T8918 323-331 VB denotes inhibits
T8919 332-335 NN denotes A3G
T8920 336-344 NN denotes activity
T8921 345-347 IN denotes by
T8922 348-355 JJ denotes further
T8923 356-366 NN denotes mechanisms
T8924 367-368 -LRB- denotes (
T8925 368-369 CD denotes 8
T8926 369-370 -COMMA- denotes ,
T8927 371-376 CD denotes 37–43
T8928 376-377 -RRB- denotes )
T8929 379-381 TO denotes To
T8930 382-393 VB denotes investigate
T8931 394-401 IN denotes whether
T8932 402-405 DT denotes the
T8933 406-420 NN denotes overexpression
T8934 421-423 IN denotes of
T8935 424-429 NN denotes HIV-1
T8936 430-438 NN denotes proteins
T8937 439-443 RB denotes also
T8938 444-454 VB denotes influences
T8939 455-458 NN denotes A3G
T8940 459-467 NN denotes promoter
T8941 468-476 NN denotes activity
T8942 476-477 -COMMA- denotes ,
T8943 478-480 PRP denotes we
T8944 481-487 CC denotes either
T8945 488-497 VB denotes expressed
T8946 498-503 NN denotes HIV-1
T8947 504-507 NN denotes Vif
T8948 508-510 CC denotes or
T8949 511-514 DT denotes the
T8950 515-520 NN denotes HIV-1
T8951 521-524 NN denotes Tat
T8952 525-532 NN denotes protein
T8953 532-533 -COMMA- denotes ,
T8954 534-537 DT denotes the
T8955 538-544 JJ denotes latter
T8956 545-548 VB denotes has
T8957 549-553 VB denotes been
T8958 554-559 VB denotes shown
T8959 560-562 TO denotes to
T8960 563-571 VB denotes activate
T8961 572-581 JJ denotes different
T8962 582-587 JJ denotes viral
T8963 588-591 CC denotes and
T8964 592-600 JJ denotes cellular
T8965 601-610 NN denotes promoters
T8966 611-612 -LRB- denotes (
T8967 612-617 CD denotes 44,45
T8968 617-618 -RRB- denotes )
T8969 620-622 IN denotes In
T8970 623-631 NN denotes addition
T8971 631-632 -COMMA- denotes ,
T8972 633-643 VB denotes increasing
T8973 644-651 NN denotes amounts
T8974 652-654 IN denotes of
T8975 655-658 DT denotes the
T8976 659-666 NN denotes plasmid
T8977 667-673 NN denotes pNL4-3
T8978 673-674 -COMMA- denotes ,
T8979 675-685 VB denotes containing
T8980 686-689 DT denotes the
T8981 690-701 JJ denotes full-length
T8982 702-708 NN denotes genome
T8983 709-711 IN denotes of
T8984 712-717 NN denotes HIV-1
T8985 717-718 -COMMA- denotes ,
T8986 719-723 VB denotes were
T8987 724-735 VB denotes transfected
T8988 737-742 DT denotes These
T8989 743-753 NN denotes constructs
T8990 754-756 CC denotes or
T8991 757-760 DT denotes the
T8992 761-766 JJ denotes empty
T8993 767-773 NN denotes vector
T8994 774-782 NN denotes pcDNA3.1
T8995 783-787 VB denotes were
T8996 788-801 VB denotes cotransfected
T8997 802-806 IN denotes with
T8998 807-810 DT denotes the
T8999 811-818 NN denotes 1025 bp
T9000 819-828 NN denotes construct
T9001 829-833 IN denotes into
T9002 834-841 NN denotes A3.01 T
T9003 842-847 NN denotes cells
T9004 849-859 NN denotes Luciferase
T9005 860-866 NN denotes assays
T9006 867-873 VB denotes showed
T9007 874-878 IN denotes that
T9008 879-882 DT denotes the
T9009 883-898 JJ denotes transcriptional
T9010 899-907 NN denotes activity
T9011 908-910 IN denotes of
T9012 911-914 DT denotes the
T9013 915-918 NN denotes A3G
T9014 919-927 NN denotes promoter
T9015 928-931 VB denotes was
T9016 932-935 RB denotes not
T9017 936-949 RB denotes significantly
T9018 950-957 VB denotes altered
T9019 958-960 IN denotes in
T9020 961-964 DT denotes the
T9021 965-973 NN denotes presence
T9022 974-976 IN denotes of
T9023 977-980 NNP denotes Vif
T9024 980-981 -COMMA- denotes ,
T9025 982-985 NN denotes Tat
T9026 986-988 CC denotes or
T9027 989-999 NN denotes HIV-1NL4-3
T9028 1000-1001 -LRB- denotes (
T9029 1001-1007 NN denotes Figure
T9030 1008-1010 NN denotes 4A
T9031 1010-1011 -RRB- denotes )
T9032 1011-1012 -COMMA- denotes ,
T9033 1013-1023 VB denotes suggesting
T9034 1024-1028 IN denotes that
T9035 1029-1034 NN denotes HIV-1
T9036 1035-1037 VB denotes is
T9037 1038-1041 RB denotes not
T9038 1042-1052 VB denotes modulating
T9039 1053-1056 NN denotes A3G
T9040 1057-1067 NN denotes expression
T9041 1068-1070 IN denotes on
T9042 1071-1074 DT denotes the
T9043 1075-1090 JJ denotes transcriptional
T9044 1091-1096 NN denotes level
T9045 2690-2692 PRP denotes It
T9046 2693-2696 VB denotes has
T9047 2697-2701 VB denotes been
T9048 2702-2707 VB denotes shown
T9049 2708-2712 IN denotes that
T9050 2713-2716 DT denotes the
T9051 2717-2723 NN denotes amount
T9052 2724-2726 IN denotes of
T9053 2727-2730 NN denotes A3G
T9054 2731-2735 NN denotes mRNA
T9055 2736-2738 IN denotes in
T9056 2739-2740 NN denotes T
T9057 2741-2746 NN denotes cells
T9058 2747-2749 VB denotes is
T9059 2750-2759 VB denotes increased
T9060 2760-2762 IN denotes in
T9061 2763-2771 NN denotes response
T9062 2772-2774 TO denotes to
T9063 2775-2784 JJ denotes mitogenic
T9064 2785-2796 NN denotes stimulation
T9065 2797-2801 IN denotes with
T9066 2802-2809 NN denotes phorbol
T9067 2810-2815 NN denotes ester
T9068 2816-2817 -LRB- denotes (
T9069 2817-2822 CD denotes 46–48
T9070 2822-2823 -RRB- denotes )
T9071 2825-2827 IN denotes In
T9072 2828-2836 NN denotes addition
T9073 2836-2837 -COMMA- denotes ,
T9074 2838-2849 NN denotes interferons
T9075 2850-2854 VB denotes have
T9076 2855-2859 VB denotes been
T9077 2860-2869 VB denotes described
T9078 2870-2872 TO denotes to
T9079 2873-2883 VB denotes upregulate
T9080 2884-2887 NN denotes A3G
T9081 2888-2898 NN denotes expression
T9082 2899-2901 IN denotes in
T9083 2902-2913 NN denotes hepatocytes
T9084 2914-2917 CC denotes and
T9085 2918-2929 NN denotes macrophages
T9086 2930-2931 -LRB- denotes (
T9087 2931-2936 CD denotes 46,48
T9088 2936-2937 -RRB- denotes )
T9089 2939-2941 TO denotes To
T9090 2942-2953 VB denotes investigate
T9091 2954-2961 IN denotes whether
T9092 2962-2967 DT denotes these
T9093 2968-2975 NN denotes stimuli
T9094 2976-2985 VB denotes interfere
T9095 2986-2990 IN denotes with
T9096 2991-2994 NN denotes A3G
T9097 2995-3003 NN denotes promoter
T9098 3004-3012 NN denotes activity
T9099 3013-3015 IN denotes in
T9100 3016-3017 NN denotes T
T9101 3018-3023 NN denotes cells
T9102 3023-3024 -COMMA- denotes ,
T9103 3025-3027 PRP denotes we
T9104 3028-3039 VB denotes transfected
T9105 3040-3047 NN denotes A3.01 T
T9106 3048-3053 NN denotes cells
T9107 3054-3058 IN denotes with
T9108 3059-3062 DT denotes the
T9109 3063-3070 NN denotes 1025 bp
T9110 3071-3079 NN denotes promoter
T9111 3080-3082 CC denotes or
T9112 3083-3086 DT denotes the
T9113 3087-3092 JJ denotes empty
T9114 3093-3099 NN denotes vector
T9115 3100-3110 JJ denotes pGL3-Basic
T9116 3111-3112 -LRB- denotes (
T9117 3112-3118 NN denotes vector
T9118 3118-3119 -RRB- denotes )
T9119 3120-3123 CC denotes and
T9120 3124-3131 VB denotes treated
T9121 3132-3135 DT denotes the
T9122 3136-3141 NN denotes cells
T9123 3142-3146 IN denotes with
T9124 3147-3154 NN denotes phorbol
T9125 3155-3160 NN denotes ester
T9126 3161-3162 -LRB- denotes (
T9127 3162-3165 NN denotes TPA
T9128 3165-3166 -RRB- denotes )
T9129 3168-3171 DT denotes The
T9130 3172-3182 NN denotes luciferase
T9131 3183-3188 NN denotes assay
T9132 3189-3195 VB denotes showed
T9133 3196-3200 IN denotes that
T9134 3201-3204 DT denotes the
T9135 3205-3213 JJ denotes ∼15-fold
T9136 3214-3223 VB denotes increased
T9137 3224-3239 JJ denotes transcriptional
T9138 3240-3248 NN denotes activity
T9139 3249-3251 IN denotes of
T9140 3252-3255 DT denotes the
T9141 3256-3263 NN denotes 1025 bp
T9142 3264-3272 NN denotes promoter
T9143 3273-3281 JJ denotes relative
T9144 3282-3284 TO denotes to
T9145 3285-3288 DT denotes the
T9146 3289-3294 JJ denotes empty
T9147 3295-3301 NN denotes vector
T9148 3302-3305 VB denotes was
T9149 3306-3309 RB denotes not
T9150 3310-3317 RB denotes further
T9151 3318-3326 VB denotes enhanced
T9152 3327-3329 IN denotes by
T9153 3330-3333 NN denotes TPA
T9154 3334-3343 NN denotes treatment
T9155 3344-3345 -LRB- denotes (
T9156 3345-3351 NN denotes Figure
T9157 3352-3354 NN denotes 4B
T9158 3354-3355 -RRB- denotes )
T9159 3355-3356 -COMMA- denotes ,
T9160 3357-3365 IN denotes although
T9161 3366-3369 DT denotes the
T9162 3370-3380 JJ denotes functional
T9163 3381-3389 NN denotes activity
T9164 3390-3392 IN denotes of
T9165 3393-3396 NN denotes TPA
T9166 3397-3400 VB denotes was
T9167 3401-3410 VB denotes confirmed
T9168 3411-3413 IN denotes by
T9169 3414-3423 NN denotes induction
T9170 3424-3426 IN denotes of
T9171 3427-3430 DT denotes the
T9172 3431-3435 NN denotes SV40
T9173 3436-3455 JJ denotes promoter-containing
T9174 3456-3464 NN denotes reporter
T9175 3465-3472 NN denotes plasmid
T9176 3473-3485 NN denotes pGL3-Control
T9177 3486-3487 -LRB- denotes (
T9178 3487-3491 NN denotes data
T9179 3492-3495 RB denotes not
T9180 3496-3501 VB denotes shown
T9181 3501-3502 -RRB- denotes )
T9182 3504-3513 RB denotes Similarly
T9183 3513-3514 -COMMA- denotes ,
T9184 3515-3524 NN denotes treatment
T9185 3525-3527 IN denotes of
T9186 3528-3535 NN denotes A3.01 T
T9187 3536-3541 NN denotes cells
T9188 3542-3553 VB denotes transfected
T9189 3554-3558 IN denotes with
T9190 3559-3562 DT denotes the
T9191 3563-3566 NN denotes A3G
T9192 3567-3575 NN denotes promoter
T9193 3576-3584 NN denotes deletion
T9194 3585-3595 NN denotes constructs
T9195 3596-3600 IN denotes with
T9196 3601-3606 NN denotes IFN-α
T9197 3607-3609 CC denotes or
T9198 3610-3615 NN denotes IFN-γ
T9199 3616-3622 VB denotes showed
T9200 3623-3625 DT denotes no
T9201 3626-3632 NN denotes effect
T9202 3633-3634 -LRB- denotes (
T9203 3634-3640 NN denotes Figure
T9204 3641-3643 NN denotes 4C
T9205 3643-3644 -RRB- denotes )
T9206 3646-3659 RB denotes Interestingly
T9207 3659-3660 -COMMA- denotes ,
T9208 3661-3662 DT denotes a
T9209 3663-3670 NN denotes control
T9210 3671-3678 NN denotes plasmid
T9211 3679-3680 -LRB- denotes (
T9212 3680-3688 NN denotes pGL2-CVX
T9213 3688-3689 -RRB- denotes )
T9214 3690-3700 VB denotes containing
T9215 3701-3704 CD denotes two
T9216 3705-3719 JJ denotes IFN-responsive
T9217 3720-3723 NN denotes GAS
T9218 3724-3725 -LRB- denotes (
T9219 3725-3730 NN denotes gamma
T9220 3731-3740 VB denotes activated
T9221 3741-3749 NN denotes sequence
T9222 3749-3750 -RRB- denotes )
T9223 3751-3759 NN denotes elements
T9224 3760-3768 JJ denotes upstream
T9225 3769-3771 IN denotes of
T9226 3772-3775 DT denotes the
T9227 3776-3786 NN denotes luciferase
T9228 3787-3795 NN denotes reporter
T9229 3796-3800 NN denotes gene
T9230 3801-3804 VB denotes was
T9231 3805-3809 RB denotes only
T9232 3810-3817 VB denotes induced
T9233 3818-3820 IN denotes by
T9234 3821-3826 NN denotes IFN-α
T9235 3827-3829 IN denotes in
T9236 3830-3835 DT denotes these
T9237 3836-3841 NN denotes cells
T9238 3842-3843 -LRB- denotes (
T9239 3843-3849 NN denotes Figure
T9240 3850-3852 NN denotes 4C
T9241 3852-3853 -RRB- denotes )
T9242 3855-3860 IN denotes Since
T9243 3861-3864 CD denotes two
T9244 3865-3872 NN denotes reports
T9245 3873-3881 VB denotes describe
T9246 3882-3885 NN denotes A3G
T9247 3886-3898 NN denotes upregulation
T9248 3899-3901 IN denotes by
T9249 3902-3913 NN denotes interferons
T9250 3914-3916 IN denotes in
T9251 3917-3928 NN denotes hepatocytes
T9252 3929-3930 -LRB- denotes (
T9253 3930-3935 CD denotes 47,48
T9254 3935-3936 -RRB- denotes )
T9255 3936-3937 -COMMA- denotes ,
T9256 3938-3940 PRP denotes we
T9257 3941-3953 RB denotes additionally
T9258 3954-3963 VB denotes performed
T9259 3964-3967 DT denotes the
T9260 3968-3978 NN denotes experiment
T9261 3979-3981 IN denotes in
T9262 3982-3985 DT denotes the
T9263 3986-3993 JJ denotes hepatic
T9264 3994-3998 NN denotes cell
T9265 3999-4003 NN denotes line
T9266 4004-4009 NN denotes HepG2
T9267 4011-4013 IN denotes In
T9268 4014-4018 NN denotes line
T9269 4019-4023 IN denotes with
T9270 4024-4029 DT denotes these
T9271 4030-4042 NN denotes publications
T9272 4042-4043 -COMMA- denotes ,
T9273 4044-4046 PRP denotes we
T9274 4047-4055 VB denotes observed
T9275 4056-4058 DT denotes an
T9276 4059-4068 NN denotes induction
T9277 4069-4071 IN denotes of
T9278 4072-4075 DT denotes the
T9279 4076-4079 NN denotes A3G
T9280 4080-4088 NN denotes promoter
T9281 4089-4091 IN denotes by
T9282 4092-4105 RB denotes approximately
T9283 4106-4112 RB denotes 2-fold
T9284 4113-4118 IN denotes after
T9285 4119-4124 NN denotes IFN-α
T9286 4125-4127 CC denotes or
T9287 4128-4133 NN denotes IFN-γ
T9288 4134-4145 NN denotes stimulation
T9289 4146-4147 -LRB- denotes (
T9290 4147-4153 NN denotes Figure
T9291 4154-4156 NN denotes 4D
T9292 4156-4157 -RRB- denotes )
T9293 4158-4162 IN denotes with
T9294 4163-4168 NN denotes IFN-γ
T9295 4169-4174 VB denotes being
T9296 4175-4183 RB denotes slightly
T9297 4184-4188 RB denotes more
T9298 4189-4195 JJ denotes potent
T9299 4197-4200 IN denotes For
T9300 4201-4205 DT denotes both
T9301 4206-4216 NN denotes interferon
T9302 4217-4222 NN denotes types
T9303 4222-4223 -COMMA- denotes ,
T9304 4224-4233 NN denotes induction
T9305 4234-4236 IN denotes of
T9306 4237-4240 NN denotes A3G
T9307 4241-4249 NN denotes promoter
T9308 4250-4258 NN denotes activity
T9309 4259-4262 VB denotes was
T9310 4263-4271 VB denotes observed
T9311 4272-4275 IN denotes for
T9312 4276-4279 DT denotes all
T9313 4280-4288 NN denotes deletion
T9314 4289-4299 NN denotes constructs
T9315 4300-4306 IN denotes except
T9316 4307-4310 IN denotes for
T9317 4311-4314 DT denotes the
T9318 4315-4320 NN denotes 60 bp
T9319 4321-4329 NN denotes fragment
T9320 4329-4330 -COMMA- denotes ,
T9321 4331-4341 VB denotes indicating
T9322 4342-4346 IN denotes that
T9323 4347-4350 DT denotes the
T9324 4351-4362 JJ denotes responsible
T9325 4363-4369 NN denotes region
T9326 4370-4372 VB denotes is
T9327 4373-4380 JJ denotes located
T9328 4381-4387 IN denotes within
T9329 4388-4391 DT denotes the
T9330 4392-4397 NN denotes 60 nt
T9331 4398-4405 JJ denotes present
T9332 4406-4408 IN denotes in
T9333 4409-4412 DT denotes the
T9334 4413-4419 NN denotes 120 bp
T9335 4419-4420 -COMMA- denotes ,
T9336 4421-4424 CC denotes but
T9337 4425-4428 RB denotes not
T9338 4429-4431 IN denotes in
T9339 4432-4435 DT denotes the
T9340 4436-4441 NN denotes 60 bp
T9341 4442-4450 NN denotes fragment
T19406 1108-1111 NN denotes A3G
T19407 1112-1120 NN denotes promoter
T19408 1121-1131 NN denotes activities
T19409 1132-1137 IN denotes after
T19410 1138-1150 NN denotes coexpression
T19411 1151-1153 IN denotes of
T19412 1154-1159 NN denotes HIV-1
T19413 1160-1168 NN denotes proteins
T19414 1169-1171 CC denotes or
T19415 1172-1181 NN denotes treatment
T19416 1182-1186 IN denotes with
T19417 1187-1190 NN denotes TPA
T19418 1191-1193 CC denotes or
T19419 1194-1206 NN denotes interferons.
T19420 1207-1208 -LRB- denotes (
T19421 1208-1209 NN denotes A
T19422 1209-1210 -RRB- denotes )
T19423 1211-1218 NN denotes A3.01 T
T19424 1219-1224 NN denotes cells
T19425 1225-1229 VB denotes were
T19426 1230-1243 VB denotes cotransfected
T19427 1244-1248 IN denotes with
T19428 1249-1259 JJ denotes pGL3-Basic
T19429 1260-1268 NN denotes reporter
T19430 1269-1276 NN denotes plasmid
T19431 1277-1287 VB denotes containing
T19432 1288-1291 DT denotes the
T19433 1292-1299 NN denotes 1025 bp
T19434 1300-1303 NN denotes A3G
T19435 1304-1312 NN denotes promoter
T19436 1313-1316 CC denotes and
T19437 1317-1321 NN denotes 1 µg
T19438 1322-1324 IN denotes of
T19439 1325-1328 NN denotes Vif
T19440 1329-1339 NN denotes expression
T19441 1340-1347 NN denotes plasmid
T19442 1347-1348 -COMMA- denotes ,
T19443 1349-1353 NN denotes 1 µg
T19444 1354-1357 NN denotes Tat
T19445 1358-1368 NN denotes expression
T19446 1369-1376 NN denotes plasmid
T19447 1377-1379 CC denotes or
T19448 1380-1390 VB denotes increasing
T19449 1391-1398 NN denotes amounts
T19450 1399-1401 IN denotes of
T19451 1402-1412 NN denotes HIV-1NL4-3
T19452 1413-1414 -LRB- denotes (
T19453 1414-1417 CD denotes 0.1
T19454 1417-1418 -COMMA- denotes ,
T19455 1419-1422 CD denotes 0.5
T19456 1423-1426 CC denotes and
T19457 1427-1431 NN denotes 1 µg
T19458 1431-1432 -RRB- denotes )
T19459 1434-1439 IN denotes After
T19460 1440-1444 NN denotes 48 h
T19461 1444-1445 -COMMA- denotes ,
T19462 1446-1451 NN denotes cells
T19463 1452-1456 VB denotes were
T19464 1457-1466 VB denotes harvested
T19465 1467-1470 IN denotes for
T19466 1471-1481 NN denotes luciferase
T19467 1482-1487 NN denotes assay
T19468 1489-1496 JJ denotes Firefly
T19469 1497-1507 NN denotes luciferase
T19470 1508-1518 NN denotes activities
T19471 1519-1523 VB denotes were
T19472 1524-1534 VB denotes normalized
T19473 1535-1537 TO denotes to
T19474 1538-1549 VB denotes coexpressed
T19475 1550-1557 NN denotes renilla
T19476 1558-1568 NN denotes luciferase
T19477 1569-1580 NN denotes activities.
T19478 1581-1582 -LRB- denotes (
T19479 1582-1583 NN denotes B
T19480 1583-1584 -RRB- denotes )
T19481 1585-1592 NN denotes A3.01 T
T19482 1593-1598 NN denotes cells
T19483 1599-1603 VB denotes were
T19484 1604-1615 RB denotes transiently
T19485 1616-1627 VB denotes transfected
T19486 1628-1632 IN denotes with
T19487 1633-1643 JJ denotes pGL3-Basic
T19488 1644-1652 NN denotes reporter
T19489 1653-1660 NN denotes plasmid
T19490 1661-1671 VB denotes containing
T19491 1672-1675 DT denotes the
T19492 1676-1683 NN denotes 1025 bp
T19493 1684-1687 NN denotes A3G
T19494 1688-1696 NN denotes promoter
T19495 1697-1699 CC denotes or
T19496 1700-1704 IN denotes with
T19497 1705-1710 JJ denotes empty
T19498 1711-1717 NN denotes vector
T19499 1719-1726 CD denotes Fifteen
T19500 1727-1731 NN denotes hour
T19501 1732-1738 IN denotes before
T19502 1739-1749 VB denotes harvesting
T19503 1750-1753 IN denotes for
T19504 1754-1764 NN denotes luciferase
T19505 1765-1770 NN denotes assay
T19506 1770-1771 -COMMA- denotes ,
T19507 1772-1773 DT denotes a
T19508 1774-1780 NN denotes subset
T19509 1781-1783 IN denotes of
T19510 1784-1787 DT denotes the
T19511 1788-1792 NN denotes cell
T19512 1793-1800 NN denotes culture
T19513 1801-1804 VB denotes was
T19514 1805-1815 VB denotes stimulated
T19515 1816-1820 IN denotes with
T19516 1821-1829 NN denotes 20 ng/ml
T19517 1830-1833 NN denotes TPA
T19518 1835-1846 CD denotes Forty-eight
T19519 1847-1851 NN denotes hour
T19520 1852-1857 IN denotes after
T19521 1858-1870 NN denotes transfection
T19522 1870-1871 -COMMA- denotes ,
T19523 1872-1882 NN denotes luciferase
T19524 1883-1888 NN denotes assay
T19525 1889-1892 VB denotes was
T19526 1893-1902 VB denotes performed
T19527 1904-1911 JJ denotes Firefly
T19528 1912-1922 NN denotes luciferase
T19529 1923-1933 NN denotes activities
T19530 1934-1938 VB denotes were
T19531 1939-1949 VB denotes normalized
T19532 1950-1952 TO denotes to
T19533 1953-1964 VB denotes coexpressed
T19534 1965-1972 NN denotes renilla
T19535 1973-1983 NN denotes luciferase
T19536 1984-1994 NN denotes activities
T19537 1995-1998 CC denotes and
T19538 1999-2002 DT denotes the
T19539 2003-2009 NN denotes values
T19540 2010-2013 IN denotes for
T19541 2014-2017 DT denotes the
T19542 2018-2023 JJ denotes empty
T19543 2024-2031 NN denotes vectors
T19544 2032-2033 -LRB- denotes (
T19545 2033-2042 JJ denotes untreated
T19546 2043-2046 CC denotes and
T19547 2047-2061 JJ denotes TPA-stimulated
T19548 2061-2062 -RRB- denotes )
T19549 2063-2067 VB denotes were
T19550 2068-2071 VB denotes set
T19551 2072-2074 IN denotes as
T19552 2075-2077 CD denotes 1.
T19553 2078-2079 -LRB- denotes (
T19554 2079-2080 NN denotes C
T19555 2080-2081 -RRB- denotes )
T19556 2082-2089 NN denotes A3.01 T
T19557 2090-2095 NN denotes cells
T19558 2096-2100 VB denotes were
T19559 2101-2112 RB denotes transiently
T19560 2113-2124 VB denotes transfected
T19561 2125-2129 IN denotes with
T19562 2130-2133 DT denotes the
T19563 2134-2137 NN denotes A3G
T19564 2138-2146 NN denotes promoter
T19565 2147-2157 NN denotes constructs
T19566 2158-2160 CC denotes or
T19567 2161-2165 IN denotes with
T19568 2166-2169 DT denotes the
T19569 2170-2191 JJ denotes interferon-responsive
T19570 2192-2200 NN denotes reporter
T19571 2201-2208 NN denotes plasmid
T19572 2209-2217 NN denotes pGL2-CVX
T19573 2218-2219 -LRB- denotes (
T19574 2219-2222 NN denotes GAS
T19575 2222-2223 -RRB- denotes )
T19576 2225-2232 CD denotes Fifteen
T19577 2233-2237 NN denotes hour
T19578 2238-2244 IN denotes before
T19579 2245-2255 VB denotes harvesting
T19580 2256-2259 IN denotes for
T19581 2260-2270 NN denotes luciferase
T19582 2271-2276 NN denotes assay
T19583 2276-2277 -COMMA- denotes ,
T19584 2278-2279 DT denotes a
T19585 2280-2286 NN denotes subset
T19586 2287-2289 IN denotes of
T19587 2290-2293 DT denotes the
T19588 2294-2298 NN denotes cell
T19589 2299-2306 NN denotes culture
T19590 2307-2310 VB denotes was
T19591 2311-2321 VB denotes stimulated
T19592 2322-2326 IN denotes with
T19593 2327-2335 JJ denotes 30 ng/ml
T19594 2336-2341 NN denotes IFN-α
T19595 2342-2344 CC denotes or
T19596 2345-2350 NN denotes IFN-γ
T19597 2352-2363 CD denotes Forty-eight
T19598 2364-2368 NN denotes hour
T19599 2369-2374 IN denotes after
T19600 2375-2387 NN denotes transfection
T19601 2387-2388 -COMMA- denotes ,
T19602 2389-2399 NN denotes luciferase
T19603 2400-2405 NN denotes assay
T19604 2406-2409 VB denotes was
T19605 2410-2419 VB denotes performed
T19606 2421-2428 JJ denotes Firefly
T19607 2429-2439 NN denotes luciferase
T19608 2440-2450 NN denotes activities
T19609 2451-2455 VB denotes were
T19610 2456-2466 VB denotes normalized
T19611 2467-2469 TO denotes to
T19612 2470-2481 VB denotes coexpressed
T19613 2482-2489 NN denotes renilla
T19614 2490-2500 NN denotes luciferase
T19615 2501-2512 NN denotes activities.
T19616 2513-2514 -LRB- denotes (
T19617 2514-2515 NN denotes D
T19618 2515-2516 -RRB- denotes )
T19619 2517-2522 NN denotes HepG2
T19620 2523-2528 NN denotes cells
T19621 2529-2533 VB denotes were
T19622 2534-2538 VB denotes used
T19623 2539-2542 IN denotes for
T19624 2543-2555 NN denotes transfection
T19625 2557-2560 DT denotes The
T19626 2561-2571 NN denotes experiment
T19627 2572-2575 VB denotes was
T19628 2576-2585 VB denotes performed
T19629 2586-2588 IN denotes as
T19630 2589-2598 VB denotes described
T19631 2599-2601 IN denotes in
T19632 2602-2603 -LRB- denotes (
T19633 2603-2604 NN denotes C
T19634 2604-2605 -RRB- denotes )
T19635 2607-2611 NN denotes Mean
T19636 2612-2618 NN denotes values
T19637 2619-2620 -LRB- denotes (
T19638 2620-2623 NN denotes ±SD
T19639 2623-2624 -RRB- denotes )
T19640 2625-2627 IN denotes of
T19641 2628-2642 JJ denotes representative
T19642 2643-2654 NN denotes experiments
T19643 2655-2664 VB denotes performed
T19644 2665-2667 IN denotes in
T19645 2668-2678 NN denotes triplicate
T19646 2679-2682 VB denotes are
T19647 2683-2688 VB denotes shown
R7233 T8866 T8864 arg1Of promoter,The
R7234 T8866 T8865 arg1Of promoter,A3G
R7240 T8874 T8873 arg2Of to,According
R7241 T8877 T8874 arg2Of knowledge,to
R7242 T8877 T8875 arg1Of knowledge,the
R7243 T8877 T8876 arg1Of knowledge,current
R7244 T8879 T8880 arg1Of APOBEC3G,plays
R7246 T8880 T8878 arg1Of plays,","
R7247 T8880 T8883 arg1Of plays,in
R7248 T8882 T8880 arg2Of role,plays
R7249 T8882 T8881 arg1Of role,a
R7250 T8886 T8883 arg2Of defence,in
R7251 T8886 T8884 arg1Of defence,the
R7252 T8886 T8885 arg1Of defence,innate
R7253 T8886 T8887 arg1Of defence,against
R7254 T8888 T8887 arg2Of pathogens,against
R7255 T8888 T8889 arg1Of pathogens,like
R7256 T8890 T8889 arg2Of HIV-1,like
R7257 T8892 T8891 arg1Of latter,The
R7258 T8892 T8893 arg1Of latter,has
R7259 T8892 T8894 arg1Of latter,evolved
R7260 T8894 T8893 arg2Of evolved,has
R7261 T8896 T8894 arg2Of mechanism,evolved
R7262 T8896 T8895 arg1Of mechanism,a
R7263 T8896 T8897 modOf mechanism,to
R7264 T8898 T8897 arg1Of counteract,to
R7265 T8898 T8901 arg1Of counteract,by
R7266 T8900 T8898 arg2Of activity,counteract
R7267 T8900 T8899 arg1Of activity,A3G
R7268 T8902 T8901 arg2Of expressing,by
R7269 T8906 T8902 arg2Of Vif,expressing
R7270 T8906 T8903 arg1Of Vif,the
R7271 T8906 T8904 arg1Of Vif,regulatory
R7272 T8906 T8905 arg1Of Vif,protein
R7273 T8906 T8907 arg1Of Vif,(
R7274 T8908 T8907 arg2Of 4,(
R7275 T8909 T8907 arg3Of ),(
R7276 T8910 T8911 arg1Of Vif,induces
R7277 T8910 T8918 arg1Of Vif,inhibits
R7278 T8911 T8916 arg1Of induces,and
R7279 T8913 T8911 arg2Of degradation,induces
R7280 T8913 T8912 arg1Of degradation,proteasomal
R7281 T8913 T8914 arg1Of degradation,of
R7282 T8915 T8914 arg2Of A3G,of
R7283 T8918 T8916 arg2Of inhibits,and
R7284 T8918 T8917 arg1Of inhibits,additionally
R7285 T8920 T8918 arg2Of activity,inhibits
R7286 T8920 T8919 arg1Of activity,A3G
R7287 T8920 T8921 arg1Of activity,by
R7288 T8923 T8921 arg2Of mechanisms,by
R7289 T8923 T8922 arg1Of mechanisms,further
R7290 T8923 T8924 arg1Of mechanisms,(
R7291 T8925 T8924 arg2Of 8,(
R7292 T8925 T8926 arg1Of 8,","
R7293 T8927 T8926 arg2Of 37–43,","
R7294 T8928 T8924 arg3Of ),(
R7295 T8930 T8929 arg1Of investigate,To
R7296 T8933 T8932 arg1Of overexpression,the
R7297 T8933 T8934 arg1Of overexpression,of
R7298 T8933 T8938 arg1Of overexpression,influences
R7299 T8936 T8934 arg2Of proteins,of
R7300 T8936 T8935 arg1Of proteins,HIV-1
R7301 T8938 T8930 arg2Of influences,investigate
R7302 T8938 T8931 arg1Of influences,whether
R7303 T8938 T8937 arg1Of influences,also
R7304 T8941 T8938 arg2Of activity,influences
R7305 T8941 T8939 arg1Of activity,A3G
R7306 T8941 T8940 arg1Of activity,promoter
R7307 T8943 T8930 arg1Of we,investigate
R7308 T8943 T8945 arg1Of we,expressed
R7309 T8945 T8944 arg1Of expressed,either
R7310 T8945 T8953 arg1Of expressed,","
R7311 T8947 T8946 arg1Of Vif,HIV-1
R7312 T8947 T8948 arg1Of Vif,or
R7313 T8948 T8945 arg2Of or,expressed
R7314 T8952 T8948 arg2Of protein,or
R7315 T8952 T8949 arg1Of protein,the
R7316 T8952 T8950 arg1Of protein,HIV-1
R7317 T8952 T8951 arg1Of protein,Tat
R7318 T8953 T8929 modOf ",",To
R7319 T8953 T8942 arg1Of ",",","
R7320 T8955 T8954 arg1Of latter,the
R7321 T8955 T8956 arg1Of latter,has
R7322 T8955 T8957 arg1Of latter,been
R7323 T8955 T8958 arg2Of latter,shown
R7324 T8955 T8960 arg1Of latter,activate
R7325 T8958 T8953 arg2Of shown,","
R7326 T8958 T8956 arg2Of shown,has
R7327 T8958 T8957 arg2Of shown,been
R7328 T8960 T8958 arg3Of activate,shown
R7329 T8960 T8959 arg1Of activate,to
R7330 T8962 T8963 arg1Of viral,and
R7331 T8964 T8963 arg2Of cellular,and
R7332 T8965 T8960 arg2Of promoters,activate
R7333 T8965 T8961 arg1Of promoters,different
R7334 T8965 T8962 arg1Of promoters,viral
R7335 T8965 T8964 arg1Of promoters,cellular
R7336 T8965 T8966 arg1Of promoters,(
R7337 T8967 T8966 arg2Of "44,45",(
R7338 T8968 T8966 arg3Of ),(
R7339 T8970 T8969 arg2Of addition,In
R7340 T8973 T8972 arg1Of amounts,increasing
R7341 T8973 T8974 arg1Of amounts,of
R7342 T8973 T8978 arg1Of amounts,","
R7343 T8973 T8979 arg1Of amounts,containing
R7344 T8973 T8986 arg1Of amounts,were
R7345 T8973 T8987 arg2Of amounts,transfected
R7346 T8977 T8974 arg2Of pNL4-3,of
R7347 T8977 T8975 arg1Of pNL4-3,the
R7348 T8977 T8976 arg1Of pNL4-3,plasmid
R7349 T8982 T8979 arg2Of genome,containing
R7350 T8982 T8980 arg1Of genome,the
R7351 T8982 T8981 arg1Of genome,full-length
R7352 T8982 T8983 arg1Of genome,of
R7353 T8984 T8983 arg2Of HIV-1,of
R7354 T8987 T8969 arg1Of transfected,In
R7355 T8987 T8971 arg1Of transfected,","
R7356 T8987 T8985 arg1Of transfected,","
R7357 T8987 T8986 arg2Of transfected,were
R7358 T8989 T8988 arg1Of constructs,These
R7359 T8989 T8990 arg1Of constructs,or
R7360 T8990 T8995 arg1Of or,were
R7361 T8990 T8996 arg2Of or,cotransfected
R7362 T8994 T8990 arg2Of pcDNA3.1,or
R7363 T8994 T8991 arg1Of pcDNA3.1,the
R7364 T8994 T8992 arg1Of pcDNA3.1,empty
R7365 T8994 T8993 arg1Of pcDNA3.1,vector
R7366 T8996 T8995 arg2Of cotransfected,were
R7367 T8996 T8997 arg1Of cotransfected,with
R7368 T9000 T8997 arg2Of construct,with
R7369 T9000 T8998 arg1Of construct,the
R7370 T9000 T8999 arg1Of construct,1025 bp
R7371 T9000 T9001 arg1Of construct,into
R7372 T9003 T9001 arg2Of cells,into
R7373 T9003 T9002 arg1Of cells,A3.01 T
R7374 T9005 T9004 arg1Of assays,Luciferase
R7375 T9005 T9006 arg1Of assays,showed
R7376 T9010 T9008 arg1Of activity,the
R7377 T9010 T9009 arg1Of activity,transcriptional
R7378 T9010 T9011 arg1Of activity,of
R7379 T9010 T9015 arg1Of activity,was
R7380 T9010 T9018 arg2Of activity,altered
R7381 T9014 T9011 arg2Of promoter,of
R7382 T9014 T9012 arg1Of promoter,the
R7383 T9014 T9013 arg1Of promoter,A3G
R7384 T9018 T9006 arg2Of altered,showed
R7385 T9018 T9007 arg1Of altered,that
R7386 T9018 T9015 arg2Of altered,was
R7387 T9018 T9016 arg1Of altered,not
R7388 T9018 T9017 arg1Of altered,significantly
R7389 T9018 T9019 arg1Of altered,in
R7390 T9018 T9032 arg1Of altered,","
R7391 T9018 T9033 modOf altered,suggesting
R7392 T9021 T9019 arg2Of presence,in
R7393 T9021 T9020 arg1Of presence,the
R7394 T9021 T9022 arg1Of presence,of
R7395 T9023 T9024 arg1Of Vif,","
R7396 T9024 T9026 arg1Of ",",or
R7397 T9025 T9024 arg2Of Tat,","
R7398 T9026 T9022 arg2Of or,of
R7399 T9027 T9026 arg2Of HIV-1NL4-3,or
R7400 T9027 T9028 arg1Of HIV-1NL4-3,(
R7401 T9030 T9028 arg2Of 4A,(
R7402 T9030 T9029 arg1Of 4A,Figure
R7403 T9031 T9028 arg3Of ),(
R7404 T9035 T9036 arg1Of HIV-1,is
R7405 T9035 T9038 arg1Of HIV-1,modulating
R7406 T9038 T9033 arg2Of modulating,suggesting
R7407 T9038 T9034 arg1Of modulating,that
R7408 T9038 T9036 arg2Of modulating,is
R7409 T9038 T9037 arg1Of modulating,not
R7410 T9040 T9038 arg2Of expression,modulating
R7411 T9040 T9039 arg1Of expression,A3G
R7412 T9040 T9041 arg1Of expression,on
R7413 T9044 T9041 arg2Of level,on
R7414 T9044 T9042 arg1Of level,the
R7415 T9044 T9043 arg1Of level,transcriptional
R7416 T9045 T9046 arg1Of It,has
R7417 T9045 T9047 arg1Of It,been
R7418 T9045 T9048 arg2Of It,shown
R7419 T9048 T9046 arg2Of shown,has
R7420 T9048 T9047 arg2Of shown,been
R7421 T9051 T9050 arg1Of amount,the
R7422 T9051 T9052 arg1Of amount,of
R7423 T9051 T9055 arg1Of amount,in
R7424 T9051 T9058 arg1Of amount,is
R7425 T9051 T9059 arg2Of amount,increased
R7426 T9054 T9052 arg2Of mRNA,of
R7427 T9054 T9053 arg1Of mRNA,A3G
R7428 T9057 T9055 arg2Of cells,in
R7429 T9057 T9056 arg1Of cells,T
R7430 T9059 T9048 arg3Of increased,shown
R7431 T9059 T9049 arg1Of increased,that
R7432 T9059 T9058 arg2Of increased,is
R7433 T9059 T9060 arg1Of increased,in
R7434 T9060 T9062 arg1Of in,to
R7435 T9061 T9060 arg2Of response,in
R7436 T9064 T9060 arg3Of stimulation,in
R7437 T9064 T9063 arg1Of stimulation,mitogenic
R7438 T9064 T9065 arg1Of stimulation,with
R7439 T9067 T9065 arg2Of ester,with
R7440 T9067 T9066 arg1Of ester,phorbol
R7441 T9067 T9068 arg1Of ester,(
R7442 T9069 T9068 arg2Of 46–48,(
R7443 T9070 T9068 arg3Of ),(
R7444 T9072 T9071 arg2Of addition,In
R7445 T9074 T9075 arg1Of interferons,have
R7446 T9074 T9076 arg1Of interferons,been
R7447 T9074 T9077 arg2Of interferons,described
R7448 T9074 T9079 arg1Of interferons,upregulate
R7449 T9077 T9071 arg1Of described,In
R7450 T9077 T9073 arg1Of described,","
R7451 T9077 T9075 arg2Of described,have
R7452 T9077 T9076 arg2Of described,been
R7453 T9079 T9077 arg3Of upregulate,described
R7454 T9079 T9078 arg1Of upregulate,to
R7455 T9081 T9079 arg2Of expression,upregulate
R7456 T9081 T9080 arg1Of expression,A3G
R7457 T9081 T9082 arg1Of expression,in
R7458 T9083 T9084 arg1Of hepatocytes,and
R7459 T9084 T9082 arg2Of and,in
R7460 T9084 T9086 arg1Of and,(
R7461 T9085 T9084 arg2Of macrophages,and
R7462 T9087 T9086 arg2Of "46,48",(
R7463 T9088 T9086 arg3Of ),(
R7464 T9090 T9089 arg1Of investigate,To
R7465 T9093 T9092 arg1Of stimuli,these
R7466 T9093 T9094 arg1Of stimuli,interfere
R7467 T9094 T9095 arg1Of interfere,with
R7468 T9094 T9102 arg1Of interfere,","
R7469 T9098 T9095 arg2Of activity,with
R7470 T9098 T9096 arg1Of activity,A3G
R7471 T9098 T9097 arg1Of activity,promoter
R7472 T9098 T9099 arg1Of activity,in
R7473 T9101 T9099 arg2Of cells,in
R7474 T9101 T9100 arg1Of cells,T
R7475 T9102 T9090 arg1Of ",",investigate
R7476 T9102 T9091 arg1Of ",",whether
R7477 T9102 T9107 arg1Of ",",with
R7478 T9102 T9120 arg1Of ",",treated
R7479 T9103 T9104 arg1Of we,transfected
R7480 T9104 T9102 arg2Of transfected,","
R7481 T9106 T9104 arg2Of cells,transfected
R7482 T9106 T9105 arg1Of cells,A3.01 T
R7483 T9110 T9108 arg1Of promoter,the
R7484 T9110 T9109 arg1Of promoter,1025 bp
R7485 T9110 T9111 arg1Of promoter,or
R7486 T9111 T9107 arg2Of or,with
R7487 T9114 T9111 arg2Of vector,or
R7488 T9114 T9112 arg1Of vector,the
R7489 T9114 T9113 arg1Of vector,empty
R7490 T9114 T9115 arg1Of vector,pGL3-Basic
R7491 T9114 T9116 arg1Of vector,(
R7492 T9114 T9119 arg1Of vector,and
R7493 T9117 T9116 arg2Of vector,(
R7494 T9118 T9116 arg3Of ),(
R7495 T9120 T9089 modOf treated,To
R7496 T9122 T9120 arg2Of cells,treated
R7497 T9122 T9121 arg1Of cells,the
R7498 T9122 T9123 arg1Of cells,with
R7499 T9125 T9123 arg2Of ester,with
R7500 T9125 T9124 arg1Of ester,phorbol
R7501 T9125 T9126 arg1Of ester,(
R7502 T9127 T9126 arg2Of TPA,(
R7503 T9128 T9126 arg3Of ),(
R7504 T9131 T9129 arg1Of assay,The
R7505 T9131 T9130 arg1Of assay,luciferase
R7506 T9131 T9132 arg1Of assay,showed
R7507 T9138 T9134 arg1Of activity,the
R7508 T9138 T9135 arg1Of activity,∼15-fold
R7509 T9138 T9136 arg2Of activity,increased
R7510 T9138 T9137 arg1Of activity,transcriptional
R7511 T9138 T9139 arg1Of activity,of
R7512 T9138 T9143 arg1Of activity,relative
R7513 T9138 T9148 arg1Of activity,was
R7514 T9138 T9151 arg2Of activity,enhanced
R7515 T9142 T9139 arg2Of promoter,of
R7516 T9142 T9140 arg1Of promoter,the
R7517 T9142 T9141 arg1Of promoter,1025 bp
R7518 T9143 T9144 arg1Of relative,to
R7519 T9147 T9144 arg2Of vector,to
R7520 T9147 T9145 arg1Of vector,the
R7521 T9147 T9146 arg1Of vector,empty
R7522 T9151 T9132 arg2Of enhanced,showed
R7523 T9151 T9133 arg1Of enhanced,that
R7524 T9151 T9148 arg2Of enhanced,was
R7525 T9151 T9149 arg1Of enhanced,not
R7526 T9151 T9150 arg1Of enhanced,further
R7527 T9151 T9159 arg1Of enhanced,","
R7528 T9151 T9160 arg1Of enhanced,although
R7529 T9154 T9151 arg1Of treatment,enhanced
R7530 T9154 T9152 arg2Of treatment,by
R7531 T9154 T9153 arg1Of treatment,TPA
R7532 T9154 T9155 arg1Of treatment,(
R7533 T9157 T9155 arg2Of 4B,(
R7534 T9157 T9156 arg1Of 4B,Figure
R7535 T9158 T9155 arg3Of ),(
R7536 T9163 T9161 arg1Of activity,the
R7537 T9163 T9162 arg1Of activity,functional
R7538 T9163 T9164 arg1Of activity,of
R7539 T9163 T9166 arg1Of activity,was
R7540 T9163 T9167 arg2Of activity,confirmed
R7541 T9165 T9164 arg2Of TPA,of
R7542 T9167 T9160 arg2Of confirmed,although
R7543 T9167 T9166 arg2Of confirmed,was
R7544 T9169 T9167 arg1Of induction,confirmed
R7545 T9169 T9168 arg2Of induction,by
R7546 T9169 T9170 arg1Of induction,of
R7547 T9176 T9170 arg2Of pGL3-Control,of
R7548 T9176 T9171 arg1Of pGL3-Control,the
R7549 T9176 T9172 arg1Of pGL3-Control,SV40
R7550 T9176 T9173 arg1Of pGL3-Control,promoter-containing
R7551 T9176 T9174 arg1Of pGL3-Control,reporter
R7552 T9176 T9175 arg1Of pGL3-Control,plasmid
R7553 T9176 T9177 arg1Of pGL3-Control,(
R7554 T9178 T9177 arg2Of data,(
R7555 T9178 T9180 arg2Of data,shown
R7556 T9180 T9179 arg1Of shown,not
R7557 T9181 T9177 arg3Of ),(
R7558 T9184 T9185 arg1Of treatment,of
R7559 T9184 T9199 arg1Of treatment,showed
R7560 T9187 T9185 arg2Of cells,of
R7561 T9187 T9186 arg1Of cells,A3.01 T
R7562 T9187 T9188 arg2Of cells,transfected
R7563 T9188 T9189 arg1Of transfected,with
R7564 T9194 T9189 arg2Of constructs,with
R7565 T9194 T9190 arg1Of constructs,the
R7566 T9194 T9191 arg1Of constructs,A3G
R7567 T9194 T9192 arg1Of constructs,promoter
R7568 T9194 T9193 arg1Of constructs,deletion
R7569 T9194 T9195 arg1Of constructs,with
R7570 T9196 T9197 arg1Of IFN-α,or
R7571 T9197 T9195 arg2Of or,with
R7572 T9198 T9197 arg2Of IFN-γ,or
R7573 T9199 T9182 arg1Of showed,Similarly
R7574 T9199 T9183 arg1Of showed,","
R7575 T9201 T9199 arg2Of effect,showed
R7576 T9201 T9200 arg1Of effect,no
R7577 T9201 T9202 arg1Of effect,(
R7578 T9204 T9202 arg2Of 4C,(
R7579 T9204 T9203 arg1Of 4C,Figure
R7580 T9205 T9202 arg3Of ),(
R7581 T9210 T9208 arg1Of plasmid,a
R7582 T9210 T9209 arg1Of plasmid,control
R7583 T9210 T9211 arg1Of plasmid,(
R7584 T9210 T9214 arg1Of plasmid,containing
R7585 T9210 T9230 arg1Of plasmid,was
R7586 T9210 T9232 arg2Of plasmid,induced
R7587 T9212 T9211 arg2Of pGL2-CVX,(
R7588 T9213 T9211 arg3Of ),(
R7589 T9219 T9218 arg2Of gamma,(
R7590 T9219 T9220 arg2Of gamma,activated
R7591 T9221 T9220 arg3Of sequence,activated
R7592 T9222 T9218 arg3Of ),(
R7593 T9223 T9214 arg2Of elements,containing
R7594 T9223 T9215 arg1Of elements,two
R7595 T9223 T9216 arg1Of elements,IFN-responsive
R7596 T9223 T9217 arg1Of elements,GAS
R7597 T9223 T9218 arg1Of elements,(
R7598 T9223 T9224 arg1Of elements,upstream
R7599 T9224 T9225 arg1Of upstream,of
R7600 T9229 T9225 arg2Of gene,of
R7601 T9229 T9226 arg1Of gene,the
R7602 T9229 T9227 arg1Of gene,luciferase
R7603 T9229 T9228 arg1Of gene,reporter
R7604 T9232 T9206 arg1Of induced,Interestingly
R7605 T9232 T9207 arg1Of induced,","
R7606 T9232 T9230 arg2Of induced,was
R7607 T9232 T9231 arg1Of induced,only
R7608 T9232 T9235 arg1Of induced,in
R7609 T9234 T9232 arg1Of IFN-α,induced
R7610 T9234 T9233 arg2Of IFN-α,by
R7611 T9237 T9235 arg2Of cells,in
R7612 T9237 T9236 arg1Of cells,these
R7613 T9237 T9238 arg1Of cells,(
R7614 T9240 T9238 arg2Of 4C,(
R7615 T9240 T9239 arg1Of 4C,Figure
R7616 T9241 T9238 arg3Of ),(
R7617 T9244 T9243 arg1Of reports,two
R7618 T9244 T9245 arg1Of reports,describe
R7619 T9245 T9242 arg2Of describe,Since
R7620 T9247 T9245 arg2Of upregulation,describe
R7621 T9247 T9246 arg1Of upregulation,A3G
R7622 T9247 T9248 arg1Of upregulation,by
R7623 T9249 T9248 arg2Of interferons,by
R7624 T9249 T9250 arg1Of interferons,in
R7625 T9251 T9250 arg2Of hepatocytes,in
R7626 T9251 T9252 arg1Of hepatocytes,(
R7627 T9253 T9252 arg2Of "47,48",(
R7628 T9254 T9252 arg3Of ),(
R7629 T9256 T9258 arg1Of we,performed
R7630 T9258 T9242 arg1Of performed,Since
R7631 T9258 T9255 arg1Of performed,","
R7632 T9258 T9257 arg1Of performed,additionally
R7633 T9260 T9258 arg2Of experiment,performed
R7634 T9260 T9259 arg1Of experiment,the
R7635 T9260 T9261 arg1Of experiment,in
R7636 T9266 T9261 arg2Of HepG2,in
R7637 T9266 T9262 arg1Of HepG2,the
R7638 T9266 T9263 arg1Of HepG2,hepatic
R7639 T9266 T9264 arg1Of HepG2,cell
R7640 T9266 T9265 arg1Of HepG2,line
R7641 T9268 T9267 arg2Of line,In
R7642 T9268 T9269 arg1Of line,with
R7643 T9271 T9269 arg2Of publications,with
R7644 T9271 T9270 arg1Of publications,these
R7645 T9273 T9274 arg1Of we,observed
R7646 T9274 T9267 arg1Of observed,In
R7647 T9274 T9272 arg1Of observed,","
R7648 T9274 T9281 arg1Of observed,by
R7649 T9274 T9284 arg1Of observed,after
R7650 T9274 T9293 arg1Of observed,with
R7651 T9276 T9274 arg2Of induction,observed
R7652 T9276 T9275 arg1Of induction,an
R7653 T9276 T9277 arg1Of induction,of
R7654 T9280 T9277 arg2Of promoter,of
R7655 T9280 T9278 arg1Of promoter,the
R7656 T9280 T9279 arg1Of promoter,A3G
R7657 T9283 T9281 arg2Of 2-fold,by
R7658 T9283 T9282 arg1Of 2-fold,approximately
R7659 T9285 T9286 arg1Of IFN-α,or
R7660 T9287 T9286 arg2Of IFN-γ,or
R7661 T9288 T9284 arg2Of stimulation,after
R7662 T9288 T9285 arg1Of stimulation,IFN-α
R7663 T9288 T9287 arg1Of stimulation,IFN-γ
R7664 T9288 T9289 arg1Of stimulation,(
R7665 T9291 T9289 arg2Of 4D,(
R7666 T9291 T9290 arg1Of 4D,Figure
R7667 T9292 T9289 arg3Of ),(
R7668 T9294 T9293 arg2Of IFN-γ,with
R7669 T9294 T9295 arg1Of IFN-γ,being
R7670 T9294 T9298 arg1Of IFN-γ,potent
R7671 T9295 T9293 arg3Of being,with
R7672 T9298 T9295 arg2Of potent,being
R7673 T9298 T9296 arg1Of potent,slightly
R7674 T9298 T9297 arg1Of potent,more
R7675 T9302 T9299 arg2Of types,For
R7676 T9302 T9300 arg1Of types,both
R7677 T9302 T9301 arg1Of types,interferon
R7678 T9304 T9305 arg1Of induction,of
R7679 T9304 T9309 arg1Of induction,was
R7680 T9304 T9310 arg2Of induction,observed
R7681 T9308 T9305 arg2Of activity,of
R7682 T9308 T9306 arg1Of activity,A3G
R7683 T9308 T9307 arg1Of activity,promoter
R7684 T9310 T9299 arg1Of observed,For
R7685 T9310 T9303 arg1Of observed,","
R7686 T9310 T9309 arg2Of observed,was
R7687 T9310 T9311 arg1Of observed,for
R7688 T9310 T9320 arg1Of observed,","
R7689 T9310 T9321 modOf observed,indicating
R7690 T9314 T9311 arg2Of constructs,for
R7691 T9314 T9312 arg1Of constructs,all
R7692 T9314 T9313 arg1Of constructs,deletion
R7693 T9314 T9316 arg1Of constructs,for
R7694 T9316 T9315 arg1Of for,except
R7695 T9319 T9316 arg2Of fragment,for
R7696 T9319 T9317 arg1Of fragment,the
R7697 T9319 T9318 arg1Of fragment,60 bp
R7698 T9325 T9323 arg1Of region,the
R7699 T9325 T9324 arg1Of region,responsible
R7700 T9325 T9326 arg1Of region,is
R7701 T9325 T9327 arg1Of region,located
R7702 T9326 T9321 arg2Of is,indicating
R7703 T9326 T9322 arg1Of is,that
R7704 T9327 T9326 arg2Of located,is
R7705 T9327 T9328 arg1Of located,within
R7706 T9330 T9328 arg2Of 60 nt,within
R7707 T9330 T9329 arg1Of 60 nt,the
R7708 T9330 T9331 arg1Of 60 nt,present
R7709 T9331 T9332 arg1Of present,in
R7710 T9331 T9338 arg1Of present,in
R7711 T9332 T9336 arg1Of in,but
R7712 T9334 T9332 arg2Of 120 bp,in
R7713 T9334 T9333 arg1Of 120 bp,the
R7714 T9336 T9335 arg1Of but,","
R7715 T9338 T9336 arg2Of in,but
R7716 T9338 T9337 arg1Of in,not
R7717 T9341 T9338 arg2Of fragment,in
R7718 T9341 T9339 arg1Of fragment,the
R7719 T9341 T9340 arg1Of fragment,60 bp
R15642 T19408 T19406 arg1Of activities,A3G
R15643 T19408 T19407 arg1Of activities,promoter
R15644 T19408 T19409 arg1Of activities,after
R15645 T19410 T19411 arg1Of coexpression,of
R15646 T19410 T19414 arg1Of coexpression,or
R15647 T19413 T19411 arg2Of proteins,of
R15648 T19413 T19412 arg1Of proteins,HIV-1
R15649 T19414 T19409 arg2Of or,after
R15650 T19415 T19414 arg2Of treatment,or
R15651 T19415 T19416 arg1Of treatment,with
R15652 T19415 T19425 modOf treatment,were
R15653 T19417 T19418 arg1Of TPA,or
R15654 T19418 T19416 arg2Of or,with
R15655 T19418 T19420 arg1Of or,(
R15656 T19419 T19418 arg2Of interferons.,or
R15657 T19421 T19420 arg2Of A,(
R15658 T19422 T19420 arg3Of ),(
R15659 T19424 T19423 arg1Of cells,A3.01 T
R15660 T19424 T19425 arg1Of cells,were
R15661 T19424 T19426 arg2Of cells,cotransfected
R15662 T19426 T19425 arg2Of cotransfected,were
R15663 T19426 T19427 arg1Of cotransfected,with
R15664 T19430 T19428 arg1Of plasmid,pGL3-Basic
R15665 T19430 T19429 arg1Of plasmid,reporter
R15666 T19430 T19431 arg1Of plasmid,containing
R15667 T19430 T19436 arg1Of plasmid,and
R15668 T19435 T19431 arg2Of promoter,containing
R15669 T19435 T19432 arg1Of promoter,the
R15670 T19435 T19433 arg1Of promoter,1025 bp
R15671 T19435 T19434 arg1Of promoter,A3G
R15672 T19436 T19427 arg2Of and,with
R15673 T19436 T19452 arg1Of and,(
R15674 T19437 T19436 arg2Of 1 µg,and
R15675 T19437 T19438 arg1Of 1 µg,of
R15676 T19441 T19439 arg1Of plasmid,Vif
R15677 T19441 T19440 arg1Of plasmid,expression
R15678 T19441 T19442 arg1Of plasmid,","
R15679 T19442 T19447 arg1Of ",",or
R15680 T19446 T19442 arg2Of plasmid,","
R15681 T19446 T19443 arg1Of plasmid,1 µg
R15682 T19446 T19444 arg1Of plasmid,Tat
R15683 T19446 T19445 arg1Of plasmid,expression
R15684 T19447 T19438 arg2Of or,of
R15685 T19449 T19447 arg2Of amounts,or
R15686 T19449 T19448 arg1Of amounts,increasing
R15687 T19449 T19450 arg1Of amounts,of
R15688 T19451 T19450 arg2Of HIV-1NL4-3,of
R15689 T19453 T19454 arg1Of 0.1,","
R15690 T19454 T19456 arg1Of ",",and
R15691 T19455 T19454 arg2Of 0.5,","
R15692 T19456 T19452 arg2Of and,(
R15693 T19457 T19456 arg2Of 1 µg,and
R15694 T19458 T19452 arg3Of ),(
R15695 T19460 T19459 arg2Of 48 h,After
R15696 T19462 T19463 arg1Of cells,were
R15697 T19462 T19464 arg2Of cells,harvested
R15698 T19464 T19459 arg1Of harvested,After
R15699 T19464 T19461 arg1Of harvested,","
R15700 T19464 T19463 arg2Of harvested,were
R15701 T19464 T19465 arg1Of harvested,for
R15702 T19467 T19465 arg2Of assay,for
R15703 T19467 T19466 arg1Of assay,luciferase
R15704 T19470 T19468 arg1Of activities,Firefly
R15705 T19470 T19469 arg1Of activities,luciferase
R15706 T19470 T19471 arg1Of activities,were
R15707 T19470 T19472 arg2Of activities,normalized
R15708 T19472 T19471 arg2Of normalized,were
R15709 T19472 T19473 arg1Of normalized,to
R15710 T19477 T19473 arg2Of activities.,to
R15711 T19477 T19474 arg2Of activities.,coexpressed
R15712 T19477 T19475 arg1Of activities.,renilla
R15713 T19477 T19476 arg1Of activities.,luciferase
R15714 T19477 T19483 modOf activities.,were
R15715 T19479 T19478 arg2Of B,(
R15716 T19480 T19478 arg3Of ),(
R15717 T19482 T19478 arg1Of cells,(
R15718 T19482 T19481 arg1Of cells,A3.01 T
R15719 T19482 T19483 arg1Of cells,were
R15720 T19482 T19485 arg2Of cells,transfected
R15721 T19485 T19483 arg2Of transfected,were
R15722 T19485 T19484 arg1Of transfected,transiently
R15723 T19485 T19486 arg1Of transfected,with
R15724 T19485 T19496 arg1Of transfected,with
R15725 T19486 T19495 arg1Of with,or
R15726 T19489 T19486 arg2Of plasmid,with
R15727 T19489 T19487 arg1Of plasmid,pGL3-Basic
R15728 T19489 T19488 arg1Of plasmid,reporter
R15729 T19489 T19490 arg1Of plasmid,containing
R15730 T19494 T19490 arg2Of promoter,containing
R15731 T19494 T19491 arg1Of promoter,the
R15732 T19494 T19492 arg1Of promoter,1025 bp
R15733 T19494 T19493 arg1Of promoter,A3G
R15734 T19496 T19495 arg2Of with,or
R15735 T19498 T19496 arg2Of vector,with
R15736 T19498 T19497 arg1Of vector,empty
R15737 T19500 T19499 arg1Of hour,Fifteen
R15738 T19501 T19500 arg1Of before,hour
R15739 T19502 T19501 arg2Of harvesting,before
R15740 T19502 T19503 arg1Of harvesting,for
R15741 T19505 T19503 arg2Of assay,for
R15742 T19505 T19504 arg1Of assay,luciferase
R15743 T19508 T19507 arg1Of subset,a
R15744 T19508 T19509 arg1Of subset,of
R15745 T19508 T19513 arg1Of subset,was
R15746 T19508 T19514 arg2Of subset,stimulated
R15747 T19512 T19509 arg2Of culture,of
R15748 T19512 T19510 arg1Of culture,the
R15749 T19512 T19511 arg1Of culture,cell
R15750 T19514 T19501 arg1Of stimulated,before
R15751 T19514 T19506 arg1Of stimulated,","
R15752 T19514 T19513 arg2Of stimulated,was
R15753 T19514 T19515 arg1Of stimulated,with
R15754 T19517 T19515 arg2Of TPA,with
R15755 T19517 T19516 arg1Of TPA,20 ng/ml
R15756 T19519 T19518 arg1Of hour,Forty-eight
R15757 T19520 T19519 arg1Of after,hour
R15758 T19521 T19520 arg2Of transfection,after
R15759 T19524 T19523 arg1Of assay,luciferase
R15760 T19524 T19525 arg1Of assay,was
R15761 T19524 T19526 arg2Of assay,performed
R15762 T19526 T19520 arg1Of performed,after
R15763 T19526 T19522 arg1Of performed,","
R15764 T19526 T19525 arg2Of performed,was
R15765 T19529 T19527 arg1Of activities,Firefly
R15766 T19529 T19528 arg1Of activities,luciferase
R15767 T19529 T19530 arg1Of activities,were
R15768 T19529 T19531 arg2Of activities,normalized
R15769 T19529 T19558 arg1Of activities,were
R15770 T19529 T19560 arg2Of activities,transfected
R15771 T19531 T19530 arg2Of normalized,were
R15772 T19531 T19532 arg1Of normalized,to
R15773 T19531 T19537 arg1Of normalized,and
R15774 T19536 T19532 arg2Of activities,to
R15775 T19536 T19533 arg2Of activities,coexpressed
R15776 T19536 T19534 arg1Of activities,renilla
R15777 T19536 T19535 arg1Of activities,luciferase
R15778 T19539 T19538 arg1Of values,the
R15779 T19539 T19540 arg1Of values,for
R15780 T19539 T19549 arg1Of values,were
R15781 T19539 T19550 arg2Of values,set
R15782 T19543 T19540 arg2Of vectors,for
R15783 T19543 T19541 arg1Of vectors,the
R15784 T19543 T19542 arg1Of vectors,empty
R15785 T19543 T19544 arg1Of vectors,(
R15786 T19545 T19546 arg1Of untreated,and
R15787 T19547 T19544 arg2Of TPA-stimulated,(
R15788 T19547 T19545 arg1Of TPA-stimulated,untreated
R15789 T19548 T19544 arg3Of ),(
R15790 T19550 T19549 arg2Of set,were
R15791 T19550 T19551 arg1Of set,as
R15792 T19554 T19553 arg2Of C,(
R15793 T19555 T19553 arg3Of ),(
R15794 T19557 T19551 arg2Of cells,as
R15795 T19557 T19552 arg1Of cells,1.
R15796 T19557 T19553 arg1Of cells,(
R15797 T19557 T19556 arg1Of cells,A3.01 T
R15798 T19560 T19537 arg2Of transfected,and
R15799 T19560 T19549 modOf transfected,were
R15800 T19560 T19558 arg2Of transfected,were
R15801 T19560 T19559 arg1Of transfected,transiently
R15802 T19560 T19561 arg1Of transfected,with
R15803 T19560 T19567 arg1Of transfected,with
R15804 T19561 T19566 arg1Of with,or
R15805 T19565 T19561 arg2Of constructs,with
R15806 T19565 T19562 arg1Of constructs,the
R15807 T19565 T19563 arg1Of constructs,A3G
R15808 T19565 T19564 arg1Of constructs,promoter
R15809 T19567 T19566 arg2Of with,or
R15810 T19572 T19567 arg2Of pGL2-CVX,with
R15811 T19572 T19568 arg1Of pGL2-CVX,the
R15812 T19572 T19569 arg1Of pGL2-CVX,interferon-responsive
R15813 T19572 T19570 arg1Of pGL2-CVX,reporter
R15814 T19572 T19571 arg1Of pGL2-CVX,plasmid
R15815 T19572 T19573 arg1Of pGL2-CVX,(
R15816 T19574 T19573 arg2Of GAS,(
R15817 T19575 T19573 arg3Of ),(
R15818 T19577 T19576 arg1Of hour,Fifteen
R15819 T19578 T19577 arg1Of before,hour
R15820 T19579 T19578 arg2Of harvesting,before
R15821 T19579 T19580 arg1Of harvesting,for
R15822 T19582 T19580 arg2Of assay,for
R15823 T19582 T19581 arg1Of assay,luciferase
R15824 T19585 T19584 arg1Of subset,a
R15825 T19585 T19586 arg1Of subset,of
R15826 T19585 T19590 arg1Of subset,was
R15827 T19585 T19591 arg2Of subset,stimulated
R15828 T19589 T19586 arg2Of culture,of
R15829 T19589 T19587 arg1Of culture,the
R15830 T19589 T19588 arg1Of culture,cell
R15831 T19591 T19578 arg1Of stimulated,before
R15832 T19591 T19583 arg1Of stimulated,","
R15833 T19591 T19590 arg2Of stimulated,was
R15834 T19591 T19592 arg1Of stimulated,with
R15835 T19594 T19595 arg1Of IFN-α,or
R15836 T19595 T19592 arg2Of or,with
R15837 T19595 T19593 arg1Of or,30 ng/ml
R15838 T19596 T19595 arg2Of IFN-γ,or
R15839 T19598 T19597 arg1Of hour,Forty-eight
R15840 T19599 T19598 arg1Of after,hour
R15841 T19600 T19599 arg2Of transfection,after
R15842 T19603 T19602 arg1Of assay,luciferase
R15843 T19603 T19604 arg1Of assay,was
R15844 T19603 T19605 arg2Of assay,performed
R15845 T19605 T19599 arg1Of performed,after
R15846 T19605 T19601 arg1Of performed,","
R15847 T19605 T19604 arg2Of performed,was
R15848 T19608 T19606 arg1Of activities,Firefly
R15849 T19608 T19607 arg1Of activities,luciferase
R15850 T19608 T19609 arg1Of activities,were
R15851 T19608 T19610 arg2Of activities,normalized
R15852 T19610 T19609 arg2Of normalized,were
R15853 T19610 T19611 arg1Of normalized,to
R15854 T19610 T19623 arg1Of normalized,for
R15855 T19615 T19611 arg2Of activities.,to
R15856 T19615 T19612 arg2Of activities.,coexpressed
R15857 T19615 T19613 arg1Of activities.,renilla
R15858 T19615 T19614 arg1Of activities.,luciferase
R15859 T19615 T19616 arg1Of activities.,(
R15860 T19615 T19621 modOf activities.,were
R15861 T19617 T19616 arg2Of D,(
R15862 T19618 T19616 arg3Of ),(
R15863 T19620 T19619 arg1Of cells,HepG2
R15864 T19620 T19621 arg1Of cells,were
R15865 T19620 T19622 arg2Of cells,used
R15866 T19622 T19621 arg2Of used,were
R15867 T19624 T19623 arg2Of transfection,for
R15868 T19626 T19625 arg1Of experiment,The
R15869 T19626 T19627 arg1Of experiment,was
R15870 T19626 T19628 arg2Of experiment,performed
R15871 T19628 T19627 arg2Of performed,was
R15872 T19628 T19629 arg1Of performed,as
R15873 T19630 T19629 arg2Of described,as
R15874 T19630 T19631 arg1Of described,in
R15875 T19633 T19631 arg2Of C,in
R15876 T19633 T19632 arg2Of C,(
R15877 T19634 T19632 arg3Of ),(
R15878 T19636 T19635 arg1Of values,Mean
R15879 T19636 T19637 arg1Of values,(
R15880 T19636 T19640 arg1Of values,of
R15881 T19636 T19646 arg1Of values,are
R15882 T19636 T19647 arg2Of values,shown
R15883 T19638 T19637 arg2Of ±SD,(
R15884 T19639 T19637 arg3Of ),(
R15885 T19642 T19640 arg2Of experiments,of
R15886 T19642 T19641 arg1Of experiments,representative
R15887 T19642 T19643 arg2Of experiments,performed
R15888 T19643 T19644 arg1Of performed,in
R15889 T19645 T19644 arg2Of triplicate,in
R15890 T19647 T19646 arg2Of shown,are
R7235 T8867 T8868 arg1Of is,not
R7236 T8867 T8870 arg1Of is,in
R7237 T8869 T8867 arg2Of inducible,is
R7238 T8872 T8870 arg2Of cells,in
R7239 T8872 T8871 arg1Of cells,T
R7231 T8866 T8867 arg1Of promoter,is
R7232 T8866 T8869 arg1Of promoter,inducible
R7245 T8880 T8873 arg1Of plays,According

events-check-again

Id Subject Object Predicate Lexical cue Negation Speculation
T10137 4-7 Protein denotes A3G
T10138 8-16 Entity denotes promoter
T10139 24-33 Positive_regulation denotes inducible true
T10140 81-89 Protein denotes APOBEC3G
T10141 193-203 Negative_regulation denotes counteract
T10142 204-207 Protein denotes A3G
T10143 220-230 Gene_expression denotes expressing
T10144 254-257 Protein denotes Vif
T10145 263-266 Protein denotes Vif
T10146 267-274 Positive_regulation denotes induces
T10147 287-298 Protein_catabolism denotes degradation
T10148 302-305 Protein denotes A3G
T10149 323-331 Negative_regulation denotes inhibits
T10150 332-335 Protein denotes A3G
T10151 455-458 Protein denotes A3G
T10152 488-497 Gene_expression denotes expressed
T10153 488-497 Gene_expression denotes expressed
T10154 504-507 Protein denotes Vif
T10155 521-524 Protein denotes Tat
T10156 849-859 Protein denotes Luciferase
T10157 915-918 Protein denotes A3G
T10158 977-980 Protein denotes Vif
T10159 982-985 Protein denotes Tat
T10160 1042-1052 Regulation denotes modulating true true
T10161 1053-1056 Protein denotes A3G
T10162 1057-1067 Gene_expression denotes expression
T10163 2727-2730 Protein denotes A3G
T10164 2750-2759 Positive_regulation denotes increased
T10165 2873-2883 Positive_regulation denotes upregulate
T10166 2884-2887 Protein denotes A3G
T10167 2888-2898 Gene_expression denotes expression
T10168 2991-2994 Protein denotes A3G
T10169 3172-3182 Protein denotes luciferase
T10170 3214-3223 Positive_regulation denotes increased
T10171 3224-3239 Transcription denotes transcriptional
T10172 3240-3248 Positive_regulation denotes activity
T10173 3318-3326 Positive_regulation denotes enhanced true
T10174 3563-3566 Protein denotes A3G
T10175 3601-3606 Protein denotes IFN-α
T10176 3610-3615 Protein denotes IFN-γ
T10177 3776-3786 Protein denotes luciferase
T10178 3821-3826 Protein denotes IFN-α
T10179 3882-3885 Protein denotes A3G
T10180 3886-3898 Positive_regulation denotes upregulation
T10181 4059-4068 Positive_regulation denotes induction
T10182 4076-4079 Protein denotes A3G
T10183 4080-4088 Entity denotes promoter
T10184 4119-4124 Protein denotes IFN-α
T10185 4128-4133 Protein denotes IFN-γ
T10186 4163-4168 Protein denotes IFN-γ
T10187 4237-4240 Protein denotes A3G
T20112 1108-1111 Protein denotes A3G
T20113 1300-1303 Protein denotes A3G
T20114 1325-1328 Protein denotes Vif
T20115 1354-1357 Protein denotes Tat
T20116 1471-1481 Protein denotes luciferase
T20117 1497-1507 Protein denotes luciferase
T20118 1538-1549 Gene_expression denotes coexpressed
T20119 1538-1549 Gene_expression denotes coexpressed
T20120 1558-1568 Protein denotes luciferase
T20121 1684-1687 Protein denotes A3G
T20122 1754-1764 Protein denotes luciferase
T20123 1872-1882 Protein denotes luciferase
T20124 1912-1922 Protein denotes luciferase
T20125 1953-1964 Gene_expression denotes coexpressed
T20126 1953-1964 Gene_expression denotes coexpressed
T20127 1973-1983 Protein denotes luciferase
T20128 2134-2137 Protein denotes A3G
T20129 2170-2180 Protein denotes interferon
T20130 2260-2270 Protein denotes luciferase
T20131 2336-2341 Protein denotes IFN-α
T20132 2345-2350 Protein denotes IFN-γ
T20133 2389-2399 Protein denotes luciferase
T20134 2429-2439 Protein denotes luciferase
T20135 2470-2481 Gene_expression denotes coexpressed
T20136 2470-2481 Gene_expression denotes coexpressed
T20137 2490-2500 Protein denotes luciferase
R8317 T10138 T10139 themeOf promoter,inducible
R8318 T10138 T10137 partOf promoter,A3G
R8319 T10142 T10141 themeOf A3G,counteract
R8320 T10143 T10141 causeOf expressing,counteract
R8321 T10144 T10143 themeOf Vif,expressing
R8322 T10145 T10149 causeOf Vif,inhibits
R8323 T10145 T10146 causeOf Vif,induces
R8324 T10147 T10146 themeOf degradation,induces
R8325 T10148 T10147 themeOf A3G,degradation
R8326 T10150 T10149 themeOf A3G,inhibits
R8327 T10154 T10152 themeOf Vif,expressed
R8328 T10155 T10153 themeOf Tat,expressed
R8329 T10161 T10162 themeOf A3G,expression
R8330 T10162 T10160 themeOf expression,modulating
R8331 T10163 T10164 themeOf A3G,increased
R8332 T10166 T10167 themeOf A3G,expression
R8333 T10167 T10165 themeOf expression,upregulate
R8334 T10169 T10171 themeOf luciferase,transcriptional
R8335 T10170 T10173 themeOf increased,enhanced
R8336 T10171 T10170 themeOf transcriptional,increased
R8337 T10171 T10172 themeOf transcriptional,activity
R8338 T10179 T10180 themeOf A3G,upregulation
R8339 T10183 T10181 themeOf promoter,induction
R8340 T10183 T10182 partOf promoter,A3G
R16189 T20117 T20118 themeOf luciferase,coexpressed
R16190 T20120 T20119 themeOf luciferase,coexpressed
R16191 T20124 T20126 themeOf luciferase,coexpressed
R16192 T20127 T20125 themeOf luciferase,coexpressed
R16193 T20134 T20136 themeOf luciferase,coexpressed
R16194 T20137 T20135 themeOf luciferase,coexpressed

bionlp-st-ge-2016-reference-tees

Id Subject Object Predicate Lexical cue
T10188 4-16 Protein denotes A3G promoter
T10189 24-33 Positive_regulation denotes inducible
T10190 81-89 Protein denotes APOBEC3G
T10191 204-207 Protein denotes A3G
T10192 193-203 Negative_regulation denotes counteract
T10193 302-305 Protein denotes A3G
T10194 332-335 Protein denotes A3G
T10195 287-298 Protein_catabolism denotes degradation
T10196 323-331 Negative_regulation denotes inhibits
T10197 267-274 Positive_regulation denotes induces
T10198 455-467 Protein denotes A3G promoter
T10199 498-507 Protein denotes HIV-1 Vif
T10200 515-532 Protein denotes HIV-1 Tat protein
T10201 488-497 Gene_expression denotes expressed
T10202 488-497 Gene_expression denotes expressed
T10203 849-859 Protein denotes Luciferase
T10204 915-927 Protein denotes A3G promoter
T10205 977-980 Protein denotes Vif
T10206 982-985 Protein denotes Tat
T10207 1053-1056 Protein denotes A3G
T10208 1057-1067 Gene_expression denotes expression
T10209 1042-1052 Regulation denotes modulating
T10210 2727-2735 Protein denotes A3G mRNA
T10211 2750-2759 Positive_regulation denotes increased
T10212 2884-2887 Protein denotes A3G
T10213 2888-2898 Gene_expression denotes expression
T10214 2873-2883 Positive_regulation denotes upregulate
T10215 2991-3003 Protein denotes A3G promoter
T10216 3172-3182 Protein denotes luciferase
T10217 3431-3444 Protein denotes SV40 promoter
T10218 3563-3575 Protein denotes A3G promoter
T10219 3601-3606 Protein denotes IFN-α
T10220 3610-3615 Protein denotes IFN-γ
T10221 3705-3708 Protein denotes IFN
T10222 3776-3800 Protein denotes luciferase reporter gene
T10223 3821-3826 Protein denotes IFN-α
T10224 4076-4088 Protein denotes A3G promoter
T10225 4119-4124 Protein denotes IFN-α
T10226 4128-4133 Protein denotes IFN-γ
T10227 4163-4168 Protein denotes IFN-γ
T10228 4059-4068 Positive_regulation denotes induction
T10229 4206-4216 Protein denotes interferon
T10230 4237-4249 Protein denotes A3G promoter
T10231 4224-4233 Positive_regulation denotes induction
T20138 1325-1328 Protein denotes Vif
T20139 1354-1357 Protein denotes Tat
T20140 1471-1481 Protein denotes luciferase
T20141 1489-1507 Protein denotes Firefly luciferase
T20142 1550-1568 Protein denotes renilla luciferase
T20143 1538-1549 Gene_expression denotes coexpressed
T20144 1538-1549 Gene_expression denotes coexpressed
T20145 1676-1696 Protein denotes 1025 bp A3G promoter
T20146 1754-1764 Protein denotes luciferase
T20147 1872-1882 Protein denotes luciferase
T20148 1904-1922 Protein denotes Firefly luciferase
T20149 1965-1983 Protein denotes renilla luciferase
T20150 1953-1964 Gene_expression denotes coexpressed
T20151 1953-1964 Gene_expression denotes coexpressed
T20152 2134-2157 Protein denotes A3G promoter constructs
T20153 2170-2180 Protein denotes interferon
T20154 2260-2270 Protein denotes luciferase
T20155 2336-2341 Protein denotes IFN-α
T20156 2345-2350 Protein denotes IFN-γ
T20157 2389-2399 Protein denotes luciferase
T20158 2421-2439 Protein denotes Firefly luciferase
T20159 2482-2500 Protein denotes renilla luciferase
T20160 2470-2481 Gene_expression denotes coexpressed
T20161 2470-2481 Gene_expression denotes coexpressed
R8341 T10188 T10189 themeOf A3G promoter,inducible
R8342 T10191 T10192 themeOf A3G,counteract
R8343 T10193 T10195 themeOf A3G,degradation
R8344 T10194 T10196 themeOf A3G,inhibits
R8345 T10195 T10197 themeOf degradation,induces
R8346 T10199 T10201 themeOf HIV-1 Vif,expressed
R8347 T10200 T10202 themeOf HIV-1 Tat protein,expressed
R8348 T10207 T10208 themeOf A3G,expression
R8349 T10208 T10209 themeOf expression,modulating
R8350 T10210 T10211 themeOf A3G mRNA,increased
R8351 T10212 T10213 themeOf A3G,expression
R8352 T10213 T10214 themeOf expression,upregulate
R8353 T10224 T10228 themeOf A3G promoter,induction
R8354 T10230 T10231 themeOf A3G promoter,induction
R16195 T20141 T20143 themeOf Firefly luciferase,coexpressed
R16196 T20142 T20144 themeOf renilla luciferase,coexpressed
R16197 T20148 T20150 themeOf Firefly luciferase,coexpressed
R16198 T20149 T20151 themeOf renilla luciferase,coexpressed
R16199 T20158 T20160 themeOf Firefly luciferase,coexpressed
R16200 T20159 T20161 themeOf renilla luciferase,coexpressed

bionlp-st-ge-2016-reference

Id Subject Object Predicate Lexical cue Negation Speculation
T8785 982-985 Protein denotes Tat
T8786 1042-1052 Regulation denotes modulating true true
T8787 1053-1056 Protein denotes A3G
T8788 1057-1067 Gene_expression denotes expression
T8789 2727-2730 Protein denotes A3G
T8790 2750-2759 Positive_regulation denotes increased
T8791 2873-2883 Positive_regulation denotes upregulate
T8792 2884-2887 Protein denotes A3G
T8793 2888-2898 Gene_expression denotes expression
T8794 2991-2994 Protein denotes A3G
T8795 3172-3182 Protein denotes luciferase
T8796 3214-3223 Positive_regulation denotes increased
T8797 3224-3239 Transcription denotes transcriptional
T8798 3240-3248 Positive_regulation denotes activity
T8799 3318-3326 Positive_regulation denotes enhanced true
T8800 3563-3566 Protein denotes A3G
T8801 3601-3606 Protein denotes IFN-α
T8802 3610-3615 Protein denotes IFN-γ
T8803 3776-3786 Protein denotes luciferase
T8804 3821-3826 Protein denotes IFN-α
T8805 3882-3885 Protein denotes A3G
T8806 3886-3898 Positive_regulation denotes upregulation
T8807 4059-4068 Positive_regulation denotes induction
T8808 4076-4079 Protein denotes A3G
T8809 4080-4088 Entity denotes promoter
T8810 4119-4124 Protein denotes IFN-α
T8811 4128-4133 Protein denotes IFN-γ
T8812 4163-4168 Protein denotes IFN-γ
T8813 4237-4240 Protein denotes A3G
T19338 1108-1111 Protein denotes A3G
T19339 1300-1303 Protein denotes A3G
T19340 1325-1328 Protein denotes Vif
T19341 1354-1357 Protein denotes Tat
T19342 1471-1481 Protein denotes luciferase
T19343 1497-1507 Protein denotes luciferase
T19344 1538-1549 Gene_expression denotes coexpressed
T19345 1538-1549 Gene_expression denotes coexpressed
T19346 1558-1568 Protein denotes luciferase
T19347 1684-1687 Protein denotes A3G
T19348 1754-1764 Protein denotes luciferase
T19349 1872-1882 Protein denotes luciferase
T19350 1912-1922 Protein denotes luciferase
T19351 1953-1964 Gene_expression denotes coexpressed
T19352 1953-1964 Gene_expression denotes coexpressed
T19353 1973-1983 Protein denotes luciferase
T19354 2134-2137 Protein denotes A3G
T19355 2170-2180 Protein denotes interferon
T19356 2260-2270 Protein denotes luciferase
T19357 2336-2341 Protein denotes IFN-α
T19358 2345-2350 Protein denotes IFN-γ
T19359 2389-2399 Protein denotes luciferase
T19360 2429-2439 Protein denotes luciferase
T19361 2470-2481 Gene_expression denotes coexpressed
T19362 2470-2481 Gene_expression denotes coexpressed
T19363 2490-2500 Protein denotes luciferase
T8763 4-7 Protein denotes A3G
T8764 8-16 Entity denotes promoter
T8765 24-33 Positive_regulation denotes inducible true
T8766 81-89 Protein denotes APOBEC3G
T8767 193-203 Negative_regulation denotes counteract
T8768 204-207 Protein denotes A3G
T8769 220-230 Gene_expression denotes expressing
T8770 254-257 Protein denotes Vif
T8771 263-266 Protein denotes Vif
T8772 267-274 Positive_regulation denotes induces
T8773 287-298 Protein_catabolism denotes degradation
T8774 302-305 Protein denotes A3G
T8775 323-331 Negative_regulation denotes inhibits
T8776 332-335 Protein denotes A3G
T8777 455-458 Protein denotes A3G
T8778 488-497 Gene_expression denotes expressed
T8779 488-497 Gene_expression denotes expressed
T8780 504-507 Protein denotes Vif
T8781 521-524 Protein denotes Tat
T8782 849-859 Protein denotes Luciferase
T8783 915-918 Protein denotes A3G
T8784 977-980 Protein denotes Vif
R7180 T8764 T8765 themeOf promoter,inducible
R7181 T8764 T8763 partOf promoter,A3G
R7182 T8768 T8767 themeOf A3G,counteract
R7183 T8769 T8767 causeOf expressing,counteract
R7184 T8770 T8769 themeOf Vif,expressing
R7185 T8771 T8775 causeOf Vif,inhibits
R7186 T8771 T8772 causeOf Vif,induces
R7187 T8773 T8772 themeOf degradation,induces
R7188 T8774 T8773 themeOf A3G,degradation
R7189 T8776 T8775 themeOf A3G,inhibits
R7190 T8780 T8778 themeOf Vif,expressed
R7191 T8781 T8779 themeOf Tat,expressed
R7192 T8787 T8788 themeOf A3G,expression
R7193 T8788 T8786 themeOf expression,modulating
R7194 T8789 T8790 themeOf A3G,increased
R7195 T8792 T8793 themeOf A3G,expression
R7196 T8793 T8791 themeOf expression,upregulate
R7197 T8795 T8797 themeOf luciferase,transcriptional
R7198 T8796 T8799 themeOf increased,enhanced
R7199 T8797 T8796 themeOf transcriptional,increased
R7200 T8797 T8798 themeOf transcriptional,activity
R7201 T8805 T8806 themeOf A3G,upregulation
R7202 T8809 T8807 themeOf promoter,induction
R7203 T8809 T8808 partOf promoter,A3G
R15636 T19343 T19344 themeOf luciferase,coexpressed
R15637 T19346 T19345 themeOf luciferase,coexpressed
R15638 T19350 T19352 themeOf luciferase,coexpressed
R15639 T19353 T19351 themeOf luciferase,coexpressed
R15640 T19360 T19362 themeOf luciferase,coexpressed
R15641 T19363 T19361 themeOf luciferase,coexpressed

bionlp-st-ge-2016-uniprot

Id Subject Object Predicate Lexical cue
T9342 4-7 Q9HC16 denotes A3G
T9343 81-89 Q9HC16 denotes APOBEC3G
T9344 204-207 Q9HC16 denotes A3G
T9345 254-257 P12504 denotes Vif
T9346 263-266 P12504 denotes Vif
T9347 302-305 Q9HC16 denotes A3G
T9348 332-335 Q9HC16 denotes A3G
T9349 455-458 Q9HC16 denotes A3G
T9350 504-507 P12504 denotes Vif
T9351 521-524 P04608 denotes Tat
T9352 521-524 P04610 denotes Tat
T9353 521-524 Q8UMQ1 denotes Tat
T9354 521-524 P04605 denotes Tat
T9355 849-859 P08659 denotes Luciferase
T9356 915-918 Q9HC16 denotes A3G
T9357 977-980 P12504 denotes Vif
T9358 982-985 P04610 denotes Tat
T9359 982-985 Q8UMQ1 denotes Tat
T9360 982-985 P04605 denotes Tat
T9361 982-985 P04608 denotes Tat
T9362 1053-1056 Q9HC16 denotes A3G
T9363 2727-2730 Q9HC16 denotes A3G
T9364 2884-2887 Q9HC16 denotes A3G
T9365 2991-2994 Q9HC16 denotes A3G
T9366 3172-3182 P08659 denotes luciferase
T9367 3273-3281 Q04864 denotes relative
T9368 3563-3566 Q9HC16 denotes A3G
T9369 3601-3606 P01562 denotes IFN-α
T9370 3610-3615 P01579 denotes IFN-γ
T9371 3776-3786 P08659 denotes luciferase
T9372 3821-3826 P01562 denotes IFN-α
T9373 3882-3885 Q9HC16 denotes A3G
T9374 4076-4079 Q9HC16 denotes A3G
T9375 4119-4124 P01562 denotes IFN-α
T9376 4128-4133 P01579 denotes IFN-γ
T9377 4163-4168 P01579 denotes IFN-γ
T9378 4237-4240 Q9HC16 denotes A3G
T19648 1108-1111 Q9HC16 denotes A3G
T19649 1300-1303 Q9HC16 denotes A3G
T19650 1325-1328 P12504 denotes Vif
T19651 1354-1357 P04610 denotes Tat
T19652 1354-1357 P04608 denotes Tat
T19653 1354-1357 P04605 denotes Tat
T19654 1354-1357 Q8UMQ1 denotes Tat
T19655 1471-1481 P08659 denotes luciferase
T19656 1497-1507 P08659 denotes luciferase
T19657 1558-1568 P08659 denotes luciferase
T19658 1684-1687 Q9HC16 denotes A3G
T19659 1754-1764 P08659 denotes luciferase
T19660 1872-1882 P08659 denotes luciferase
T19661 1912-1922 P08659 denotes luciferase
T19662 1973-1983 P08659 denotes luciferase
T19663 2134-2137 Q9HC16 denotes A3G
T19664 2260-2270 P08659 denotes luciferase
T19665 2336-2341 P01562 denotes IFN-α
T19666 2345-2350 P01579 denotes IFN-γ
T19667 2389-2399 P08659 denotes luciferase
T19668 2429-2439 P08659 denotes luciferase
T19669 2490-2500 P08659 denotes luciferase