PMC:1914394 / 45174-45370 JSONTXT

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{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T22962","span":{"begin":9,"end":18},"obj":"GO:0065007"},{"id":"T22963","span":{"begin":19,"end":23},"obj":"PR_EXT:000006852"},{"id":"T22964","span":{"begin":40,"end":46},"obj":"UBERON:0000966"},{"id":"T22965","span":{"begin":91,"end":93},"obj":"PR_EXT:000013773"},{"id":"T22966","span":{"begin":106,"end":116},"obj":"GO:0010467"},{"id":"T22967","span":{"begin":139,"end":143},"obj":"CL_GO_EXT:cell"},{"id":"T22968","span":{"begin":139,"end":152},"obj":"GO:0051301"},{"id":"T22969","span":{"begin":166,"end":175},"obj":"GO:0006915"}],"text":" Thus, deregulated E2f1 activity in the retina, whether resulting from the inactivation of Rb or from overexpression, promotes unscheduled cell division and triggers apoptosis in susceptible RTCs."}

{"project":"craft-ca-core-dev","denotations":[{"id":"T22836","span":{"begin":9,"end":18},"obj":"GO:0065007"},{"id":"T22837","span":{"begin":19,"end":23},"obj":"PR:000006852"},{"id":"T22838","span":{"begin":40,"end":46},"obj":"UBERON:0000966"},{"id":"T22839","span":{"begin":91,"end":93},"obj":"PR:000013773"},{"id":"T22840","span":{"begin":106,"end":116},"obj":"GO:0010467"},{"id":"T22841","span":{"begin":139,"end":152},"obj":"GO:0051301"},{"id":"T22842","span":{"begin":166,"end":175},"obj":"GO:0006915"}],"text":" Thus, deregulated E2f1 activity in the retina, whether resulting from the inactivation of Rb or from overexpression, promotes unscheduled cell division and triggers apoptosis in susceptible RTCs."}