Table 1 Experimental groups used for gene expression profiling Group Treatment RNA source No. of mice CV (percentage) DBA/1_NC None LN from naive control DBA/1 3 22.8 DBA/1_PI CFA + collagen II LN from DBA/1 at day 10 after immunisation 3 20.4 DBA/1_OA CFA + collagen II LN from DBA/1 mice at day 35 after immunisation 3 21.7 DBA/1_CA CFA + collagen II LN from DBA/1 mice at day 95 after immunisation 3 25.8 FVB/N_NC None LN from naive control FVB/N 3 21.1 FVB/N_PI CFA + collagen II LN from FVB/N at day 10 after immunisation 3 22.6 FVB/N_OA CFA + collagen II LN from FVB/N mice at day 35 after immunisation 3 18.4 FVB/N_CA CFA + collagen II LN from FVB/N mice at day 95 after immunisation 3 21.1 CA, chronic arthritis; CFA; complete Freund's adjuvant; CV, coefficient of variation; LN, lymph node; NC, naive control; OA, onset of arthritis; PI, post-immunisation.