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PMC:1860061 / 24790-25644 JSONTXT

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craft-sa-dev

Id Subject Object Predicate Lexical cue
T14922 11-13 PRP denotes We
T14923 14-21 VBP denotes present
T14924 22-23 DT denotes a
T14925 24-32 NN denotes strategy
T14926 33-35 TO denotes to
T14927 36-42 VB denotes search
T14928 43-52 NN denotes candidate
T14929 53-58 NNS denotes genes
T14930 59-62 IN denotes for
T14931 63-68 JJ denotes small
T14932 69-75 NN denotes effect
T14933 68-69 HYPH denotes -
T14934 76-79 NNS denotes QTL
T14935 79-80 . denotes .
T14936 80-187 sentence denotes With this strategy, we identified 21 candidate genes for 8 small-effect QTL regulating CIA susceptibility.
T14937 81-85 IN denotes With
T14938 104-114 VBD denotes identified
T14939 86-90 DT denotes this
T14940 91-99 NN denotes strategy
T14941 99-101 , denotes ,
T14942 101-103 PRP denotes we
T14943 115-117 CD denotes 21
T14944 128-133 NNS denotes genes
T14945 118-127 NN denotes candidate
T14946 134-137 IN denotes for
T14947 138-139 CD denotes 8
T14948 172-186 NN denotes susceptibility
T14949 140-145 JJ denotes small
T14950 146-152 NN denotes effect
T14951 145-146 HYPH denotes -
T14952 153-156 NNS denotes QTL
T14953 157-167 VBG denotes regulating
T14954 168-171 NN denotes CIA
T14955 186-187 . denotes .
T14956 187-248 sentence denotes Our future studies will be carried out using two approaches.
T14957 188-191 PRP$ denotes Our
T14958 199-206 NNS denotes studies
T14959 192-198 JJ denotes future
T14960 215-222 VBN denotes carried
T14961 207-211 MD denotes will
T14962 212-214 VB denotes be
T14963 223-226 RP denotes out
T14964 227-232 VBG denotes using
T14965 233-236 CD denotes two
T14966 237-247 NNS denotes approaches
T14967 247-248 . denotes .
T14968 248-409 sentence denotes The first is generating congenic animals for promising small-effect QTL that have relatively high P values and overlap with previously-identified arthritis QTL.
T14969 249-252 DT denotes The
T14970 253-258 JJ denotes first
T14971 262-272 VBG denotes generating
T14972 259-261 VBZ denotes is
T14973 273-281 JJ denotes congenic
T14974 282-289 NNS denotes animals
T14975 290-293 IN denotes for
T14976 294-303 VBG denotes promising
T14977 317-320 NNS denotes QTL
T14978 304-309 JJ denotes small
T14979 310-316 NN denotes effect
T14980 309-310 HYPH denotes -
T14981 321-325 WDT denotes that
T14982 326-330 VBP denotes have
T14983 331-341 RB denotes relatively
T14984 342-346 JJ denotes high
T14985 349-355 NNS denotes values
T14986 347-348 NN denotes P
T14987 356-359 CC denotes and
T14988 360-367 VBP denotes overlap
T14989 368-372 IN denotes with
T14990 373-383 RB denotes previously
T14991 384-394 VBN denotes identified
T14992 383-384 HYPH denotes -
T14993 405-408 NNS denotes QTL
T14994 395-404 NN denotes arthritis
T14995 408-409 . denotes .
T14996 409-498 sentence denotes The second approach is investigating candidate genes using both mouse and human studies.
T14997 410-413 DT denotes The
T14998 421-429 NN denotes approach
T14999 414-420 JJ denotes second
T15000 430-432 VBZ denotes is
T15001 433-446 VBG denotes investigating
T15002 447-456 NN denotes candidate
T15003 457-462 NNS denotes genes
T15004 463-468 VBG denotes using
T15005 469-473 CC denotes both
T15006 474-479 NN denotes mouse
T15007 490-497 NNS denotes studies
T15008 480-483 CC denotes and
T15009 484-489 JJ denotes human
T15010 497-498 . denotes .
T15011 498-601 sentence denotes Candidate genes will be selected according to their function and polymorphism between the two strains.
T15012 499-508 NN denotes Candidate
T15013 509-514 NNS denotes genes
T15014 523-531 VBN denotes selected
T15015 515-519 MD denotes will
T15016 520-522 VB denotes be
T15017 532-541 VBG denotes according
T15018 542-544 IN denotes to
T15019 545-550 PRP$ denotes their
T15020 551-559 NN denotes function
T15021 560-563 CC denotes and
T15022 564-576 NN denotes polymorphism
T15023 577-584 IN denotes between
T15024 585-588 DT denotes the
T15025 593-600 NNS denotes strains
T15026 589-592 CD denotes two
T15027 600-601 . denotes .
T15028 601-690 sentence denotes Thereafter, we will generate knock-out mice to investigate the role of the genes in CIA.
T15029 602-612 RB denotes Thereafter
T15030 622-630 VB denotes generate
T15031 612-614 , denotes ,
T15032 614-616 PRP denotes we
T15033 617-621 MD denotes will
T15034 631-636 VB denotes knock
T15035 641-645 NNS denotes mice
T15036 636-637 HYPH denotes -
T15037 637-640 RP denotes out
T15038 646-648 TO denotes to
T15039 649-660 VB denotes investigate
T15040 661-664 DT denotes the
T15041 665-669 NN denotes role
T15042 670-672 IN denotes of
T15043 673-676 DT denotes the
T15044 677-682 NNS denotes genes
T15045 683-685 IN denotes in
T15046 686-689 NN denotes CIA
T15047 689-690 . denotes .
T15048 690-854 sentence denotes For the loci whose counterparts on the human genome are linked to RA, we will investigate the candidate genes using case-control association studies in RA cohorts.
T15049 691-694 IN denotes For
T15050 769-780 VB denotes investigate
T15051 695-698 DT denotes the
T15052 699-703 NNS denotes loci
T15053 704-709 WP$ denotes whose
T15054 710-722 NNS denotes counterparts
T15055 747-753 VBN denotes linked
T15056 723-725 IN denotes on
T15057 726-729 DT denotes the
T15058 736-742 NN denotes genome
T15059 730-735 JJ denotes human
T15060 743-746 VBP denotes are
T15061 754-756 IN denotes to
T15062 757-759 NN denotes RA
T15063 759-761 , denotes ,
T15064 761-763 PRP denotes we
T15065 764-768 MD denotes will
T15066 781-784 DT denotes the
T15067 795-800 NNS denotes genes
T15068 785-794 NN denotes candidate
T15069 801-806 VBG denotes using
T15070 807-811 NN denotes case
T15071 812-819 NN denotes control
T15072 811-812 HYPH denotes -
T15073 832-839 NNS denotes studies
T15074 820-831 NN denotes association
T15075 840-842 IN denotes in
T15076 843-845 NN denotes RA
T15077 846-853 NNS denotes cohorts
T15078 853-854 . denotes .
R4570 T14922 T14923 nsubj We,present
R4571 T14924 T14925 det a,strategy
R4572 T14925 T14923 dobj strategy,present
R4573 T14926 T14927 aux to,search
R4574 T14927 T14925 advcl search,strategy
R4575 T14928 T14929 compound candidate,genes
R4576 T14929 T14927 dobj genes,search
R4577 T14930 T14927 prep for,search
R4578 T14931 T14932 amod small,effect
R4579 T14932 T14934 compound effect,QTL
R4580 T14933 T14932 punct -,effect
R4581 T14934 T14930 pobj QTL,for
R4582 T14935 T14923 punct .,present
R4583 T14937 T14938 prep With,identified
R4584 T14939 T14940 det this,strategy
R4585 T14940 T14937 pobj strategy,With
R4586 T14941 T14938 punct ", ",identified
R4587 T14942 T14938 nsubj we,identified
R4588 T14943 T14944 nummod 21,genes
R4589 T14944 T14938 dobj genes,identified
R4590 T14945 T14944 compound candidate,genes
R4591 T14946 T14944 prep for,genes
R4592 T14947 T14948 nummod 8,susceptibility
R4593 T14948 T14946 pobj susceptibility,for
R4594 T14949 T14950 amod small,effect
R4595 T14950 T14948 nmod effect,susceptibility
R4596 T14951 T14950 punct -,effect
R4597 T14952 T14953 npadvmod QTL,regulating
R4598 T14953 T14948 amod regulating,susceptibility
R4599 T14954 T14948 compound CIA,susceptibility
R4600 T14955 T14938 punct .,identified
R4601 T14957 T14958 poss Our,studies
R4602 T14958 T14960 nsubjpass studies,carried
R4603 T14959 T14958 amod future,studies
R4604 T14961 T14960 aux will,carried
R4605 T14962 T14960 auxpass be,carried
R4606 T14963 T14960 prt out,carried
R4607 T14964 T14960 advcl using,carried
R4608 T14965 T14966 nummod two,approaches
R4609 T14966 T14964 dobj approaches,using
R4610 T14967 T14960 punct .,carried
R4611 T14969 T14970 det The,first
R4612 T14970 T14971 nsubj first,generating
R4613 T14972 T14971 aux is,generating
R4614 T14973 T14974 amod congenic,animals
R4615 T14974 T14971 dobj animals,generating
R4616 T14975 T14971 prep for,generating
R4617 T14976 T14977 amod promising,QTL
R4618 T14977 T14975 pobj QTL,for
R4619 T14978 T14979 amod small,effect
R4620 T14979 T14977 compound effect,QTL
R4621 T14980 T14979 punct -,effect
R4622 T14981 T14982 dep that,have
R4623 T14982 T14977 relcl have,QTL
R4624 T14983 T14984 advmod relatively,high
R4625 T14984 T14985 amod high,values
R4626 T14985 T14982 dobj values,have
R4627 T14986 T14985 compound P,values
R4628 T14987 T14982 cc and,have
R4629 T14988 T14982 conj overlap,have
R4630 T14989 T14988 prep with,overlap
R4631 T14990 T14991 advmod previously,identified
R4632 T14991 T14993 amod identified,QTL
R4633 T14992 T14991 punct -,identified
R4634 T14993 T14989 pobj QTL,with
R4635 T14994 T14993 compound arthritis,QTL
R4636 T14995 T14971 punct .,generating
R4637 T14997 T14998 det The,approach
R4638 T14998 T15000 nsubj approach,is
R4639 T14999 T14998 amod second,approach
R4640 T15001 T15000 xcomp investigating,is
R4641 T15002 T15003 compound candidate,genes
R4642 T15003 T15001 dobj genes,investigating
R4643 T15004 T15001 advcl using,investigating
R4644 T15005 T15006 preconj both,mouse
R4645 T15006 T15007 nmod mouse,studies
R4646 T15007 T15004 dobj studies,using
R4647 T15008 T15006 cc and,mouse
R4648 T15009 T15006 conj human,mouse
R4649 T15010 T15000 punct .,is
R4650 T15012 T15013 compound Candidate,genes
R4651 T15013 T15014 nsubjpass genes,selected
R4652 T15015 T15014 aux will,selected
R4653 T15016 T15014 auxpass be,selected
R4654 T15017 T15014 prep according,selected
R4655 T15018 T15017 prep to,according
R4656 T15019 T15020 poss their,function
R4657 T15020 T15018 pobj function,to
R4658 T15021 T15020 cc and,function
R4659 T15022 T15020 conj polymorphism,function
R4660 T15023 T15022 prep between,polymorphism
R4661 T15024 T15025 det the,strains
R4662 T15025 T15023 pobj strains,between
R4663 T15026 T15025 nummod two,strains
R4664 T15027 T15014 punct .,selected
R4665 T15029 T15030 advmod Thereafter,generate
R4666 T15031 T15030 punct ", ",generate
R4667 T15032 T15030 nsubj we,generate
R4668 T15033 T15030 aux will,generate
R4669 T15034 T15035 amod knock,mice
R4670 T15035 T15030 dobj mice,generate
R4671 T15036 T15034 punct -,knock
R4672 T15037 T15034 prt out,knock
R4673 T15038 T15039 aux to,investigate
R4674 T15039 T15030 advcl investigate,generate
R4675 T15040 T15041 det the,role
R4676 T15041 T15039 dobj role,investigate
R4677 T15042 T15041 prep of,role
R4678 T15043 T15044 det the,genes
R4679 T15044 T15042 pobj genes,of
R4680 T15045 T15039 prep in,investigate
R4681 T15046 T15045 pobj CIA,in
R4682 T15047 T15030 punct .,generate
R4683 T15049 T15050 prep For,investigate
R4684 T15051 T15052 det the,loci
R4685 T15052 T15049 pobj loci,For
R4686 T15053 T15054 poss whose,counterparts
R4687 T15054 T15055 dep counterparts,linked
R4688 T15055 T15052 relcl linked,loci
R4689 T15056 T15054 prep on,counterparts
R4690 T15057 T15058 det the,genome
R4691 T15058 T15056 pobj genome,on
R4692 T15059 T15058 amod human,genome
R4693 T15060 T15055 auxpass are,linked
R4694 T15061 T15055 prep to,linked
R4695 T15062 T15061 pobj RA,to
R4696 T15063 T15050 punct ", ",investigate
R4697 T15064 T15050 nsubj we,investigate
R4698 T15065 T15050 aux will,investigate
R4699 T15066 T15067 det the,genes
R4700 T15067 T15050 dobj genes,investigate
R4701 T15068 T15067 compound candidate,genes
R4702 T15069 T15050 advcl using,investigate
R4703 T15070 T15071 compound case,control
R4704 T15071 T15073 compound control,studies
R4705 T15072 T15071 punct -,control
R4706 T15073 T15069 dobj studies,using
R4707 T15074 T15073 compound association,studies
R4708 T15075 T15069 prep in,using
R4709 T15076 T15077 compound RA,cohorts
R4710 T15077 T15075 pobj cohorts,in
R4711 T15078 T15050 punct .,investigate

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T14915 509-514 SO_EXT:0000704 denotes genes
T14904 53-58 SO_EXT:0000704 denotes genes
T14905 76-79 SO_EXT:0000771 denotes QTL
T14906 128-133 SO_EXT:0000704 denotes genes
T14907 153-156 SO_EXT:0000771 denotes QTL
T14908 157-167 GO:0065007 denotes regulating
T14909 282-289 NCBITaxon:33208 denotes animals
T14910 317-320 SO_EXT:0000771 denotes QTL
T14911 405-408 SO_EXT:0000771 denotes QTL
T14912 457-462 SO_EXT:0000704 denotes genes
T14913 474-479 NCBITaxon:10088 denotes mouse
T14914 484-489 NCBITaxon:9606 denotes human
T14916 564-576 SO_EXT:polymorphism denotes polymorphism
T14917 641-645 NCBITaxon:10088 denotes mice
T14918 677-682 SO_EXT:0000704 denotes genes
T14919 730-735 NCBITaxon:9606 denotes human
T14920 736-742 SO_EXT:0001026 denotes genome
T14921 795-800 SO_EXT:0000704 denotes genes

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T14887 53-58 SO:0000704 denotes genes
T14888 76-79 SO:0000771 denotes QTL
T14889 128-133 SO:0000704 denotes genes
T14890 153-156 SO:0000771 denotes QTL
T14891 157-167 GO:0065007 denotes regulating
T14892 282-289 NCBITaxon:33208 denotes animals
T14893 317-320 SO:0000771 denotes QTL
T14894 405-408 SO:0000771 denotes QTL
T14895 457-462 SO:0000704 denotes genes
T14896 474-479 NCBITaxon:10088 denotes mouse
T14897 484-489 NCBITaxon:9606 denotes human
T14898 509-514 SO:0000704 denotes genes
T14899 641-645 NCBITaxon:10088 denotes mice
T14900 677-682 SO:0000704 denotes genes
T14901 730-735 NCBITaxon:9606 denotes human
T14902 736-742 SO:0001026 denotes genome
T14903 795-800 SO:0000704 denotes genes