PMC:1860061 / 19048-24788 JSON TXT

Annnotations TAB JSON ListView MergeView

craft-sa-dev

Id	Subject	Object	Predicate	Lexical cue
T13481	11-13	IN	denotes	In
T13482	29-38	VBD	denotes	attempted
T13483	14-18	DT	denotes	this
T13484	19-24	NN	denotes	study
T13485	24-26	,	denotes	,
T13486	26-28	PRP	denotes	we
T13487	39-42	IN	denotes	for
T13488	43-46	DT	denotes	the
T13489	53-57	NN	denotes	time
T13490	47-52	JJ	denotes	first
T13491	58-60	TO	denotes	to
T13492	61-69	VB	denotes	identify
T13493	70-75	JJ	denotes	small
T13494	76-82	NN	denotes	effect
T13495	75-76	HYPH	denotes	-
T13496	83-86	NNS	denotes	QTL
T13497	87-89	IN	denotes	in
T13498	90-92	DT	denotes	an
T13499	96-103	NN	denotes	progeny
T13500	93-95	NN	denotes	F2
T13501	103-104	.	denotes	.
T13502	104-277	sentence	denotes	Small-effect QTL are defined as those reaching the threshold value of P = 0.05 but that did not reach the significant threshold value suggested by Lander and Botstein [26].
T13503	105-110	JJ	denotes	Small
T13504	111-117	NN	denotes	effect
T13505	110-111	HYPH	denotes	-
T13506	118-121	NNS	denotes	QTL
T13507	126-133	VBN	denotes	defined
T13508	122-125	VBP	denotes	are
T13509	134-136	IN	denotes	as
T13510	137-142	DT	denotes	those
T13511	143-151	VBG	denotes	reaching
T13512	152-155	DT	denotes	the
T13513	166-171	NN	denotes	value
T13514	156-165	NN	denotes	threshold
T13515	172-174	IN	denotes	of
T13516	175-176	NN	denotes	P
T13517	179-183	CD	denotes	0.05
T13518	177-178	SYM	denotes	=
T13519	184-187	CC	denotes	but
T13520	188-192	DT	denotes	that
T13521	201-206	VB	denotes	reach
T13522	193-196	VBD	denotes	did
T13523	197-200	RB	denotes	not
T13524	207-210	DT	denotes	the
T13525	233-238	NN	denotes	value
T13526	211-222	JJ	denotes	significant
T13527	223-232	NN	denotes	threshold
T13528	239-248	VBN	denotes	suggested
T13529	249-251	IN	denotes	by
T13530	252-258	NNP	denotes	Lander
T13531	259-262	CC	denotes	and
T13532	263-271	NNP	denotes	Botstein
T13533	272-273	-LRB-	denotes	[
T13534	273-275	CD	denotes	26
T13535	275-276	-RRB-	denotes	]
T13536	276-277	.	denotes	.
T13537	277-406	sentence	denotes	Although not significant, there is evidence that most of the eight small-effect QTL likely contain susceptibility genes for CIA.
T13538	278-286	IN	denotes	Although
T13539	291-302	JJ	denotes	significant
T13540	287-290	RB	denotes	not
T13541	310-312	VBZ	denotes	is
T13542	302-304	,	denotes	,
T13543	304-309	EX	denotes	there
T13544	313-321	NN	denotes	evidence
T13545	322-326	IN	denotes	that
T13546	369-376	VBP	denotes	contain
T13547	327-331	JJS	denotes	most
T13548	332-334	IN	denotes	of
T13549	335-338	DT	denotes	the
T13550	358-361	NNS	denotes	QTL
T13551	339-344	CD	denotes	eight
T13552	345-350	JJ	denotes	small
T13553	351-357	NN	denotes	effect
T13554	350-351	HYPH	denotes	-
T13555	362-368	RB	denotes	likely
T13556	377-391	NN	denotes	susceptibility
T13557	392-397	NNS	denotes	genes
T13558	398-401	IN	denotes	for
T13559	402-405	NN	denotes	CIA
T13560	405-406	.	denotes	.
T13561	406-541	sentence	denotes	First, we performed the linkage analysis in three datasets, including all 290 F progeny, 76 C5+/+ F2 progeny and 133 C5+/- F2 progeny.
T13562	407-412	RB	denotes	First
T13563	417-426	VBD	denotes	performed
T13564	412-414	,	denotes	,
T13565	414-416	PRP	denotes	we
T13566	427-430	DT	denotes	the
T13567	439-447	NN	denotes	analysis
T13568	431-438	NN	denotes	linkage
T13569	448-450	IN	denotes	in
T13570	451-456	CD	denotes	three
T13571	457-465	NNS	denotes	datasets
T13572	465-467	,	denotes	,
T13573	467-476	VBG	denotes	including
T13574	477-480	DT	denotes	all
T13575	487-494	NN	denotes	progeny
T13576	481-484	CD	denotes	290
T13577	485-486	NN	denotes	F
T13578	494-496	,	denotes	,
T13579	496-498	CD	denotes	76
T13580	508-515	NN	denotes	progeny
T13581	499-502	NN	denotes	C5+
T13582	502-503	HYPH	denotes	/
T13583	503-504	SYM	denotes	+
T13584	505-507	NN	denotes	F2
T13585	516-519	CC	denotes	and
T13586	520-523	CD	denotes	133
T13587	533-540	NN	denotes	progeny
T13588	524-527	NN	denotes	C5+
T13589	527-528	HYPH	denotes	/
T13590	528-529	SYM	denotes	-
T13591	530-532	NN	denotes	F2
T13592	540-541	.	denotes	.
T13593	541-662	sentence	denotes	Five of the eight small-effect QTL were identified in at least two datasets, suggesting that these QTL are reproducible.
T13594	542-546	CD	denotes	Five
T13595	554-559	CD	denotes	eight
T13596	547-549	IN	denotes	of
T13597	550-553	DT	denotes	the
T13598	573-576	NNS	denotes	QTL
T13599	560-565	JJ	denotes	small
T13600	566-572	NN	denotes	effect
T13601	565-566	HYPH	denotes	-
T13602	582-592	VBN	denotes	identified
T13603	577-581	VBD	denotes	were
T13604	593-595	IN	denotes	in
T13605	596-598	RB	denotes	at
T13606	605-608	CD	denotes	two
T13607	599-604	RBS	denotes	least
T13608	609-617	NNS	denotes	datasets
T13609	617-619	,	denotes	,
T13610	619-629	VBG	denotes	suggesting
T13611	630-634	IN	denotes	that
T13612	645-648	VBP	denotes	are
T13613	635-640	DT	denotes	these
T13614	641-644	NNS	denotes	QTL
T13615	649-661	JJ	denotes	reproducible
T13616	661-662	.	denotes	.
T13617	662-791	sentence	denotes	Second, many QTL identified in the present study overlap with arthritis QTL previously identified, including loci 1, 2, 5 and 6.
T13618	663-669	RB	denotes	Second
T13619	712-719	VBP	denotes	overlap
T13620	669-671	,	denotes	,
T13621	671-675	JJ	denotes	many
T13622	676-679	NNS	denotes	QTL
T13623	680-690	VBN	denotes	identified
T13624	691-693	IN	denotes	in
T13625	694-697	DT	denotes	the
T13626	706-711	NN	denotes	study
T13627	698-705	JJ	denotes	present
T13628	720-724	IN	denotes	with
T13629	725-734	NN	denotes	arthritis
T13630	735-738	NNS	denotes	QTL
T13631	739-749	RB	denotes	previously
T13632	750-760	VBN	denotes	identified
T13633	760-762	,	denotes	,
T13634	762-771	VBG	denotes	including
T13635	772-776	NNS	denotes	loci
T13636	777-778	CD	denotes	1
T13637	778-780	,	denotes	,
T13638	780-781	CD	denotes	2
T13639	781-783	,	denotes	,
T13640	783-784	CD	denotes	5
T13641	785-788	CC	denotes	and
T13642	789-790	CD	denotes	6
T13643	790-791	.	denotes	.
T13644	791-933	sentence	denotes	In addition, syntenic analysis revealed that the counterpart genomic regions on the human genome of many of these eight QTL are linked to RA.
T13645	792-794	IN	denotes	In
T13646	823-831	VBD	denotes	revealed
T13647	795-803	NN	denotes	addition
T13648	803-805	,	denotes	,
T13649	805-813	JJ	denotes	syntenic
T13650	814-822	NN	denotes	analysis
T13651	832-836	IN	denotes	that
T13652	920-926	VBN	denotes	linked
T13653	837-840	DT	denotes	the
T13654	861-868	NNS	denotes	regions
T13655	841-852	NN	denotes	counterpart
T13656	853-860	JJ	denotes	genomic
T13657	869-871	IN	denotes	on
T13658	872-875	DT	denotes	the
T13659	882-888	NN	denotes	genome
T13660	876-881	JJ	denotes	human
T13661	889-891	IN	denotes	of
T13662	892-896	JJ	denotes	many
T13663	897-899	IN	denotes	of
T13664	900-905	DT	denotes	these
T13665	912-915	NNS	denotes	QTL
T13666	906-911	CD	denotes	eight
T13667	916-919	VBP	denotes	are
T13668	927-929	IN	denotes	to
T13669	930-932	NN	denotes	RA
T13670	932-933	.	denotes	.
T13671	933-1190	sentence	denotes	For five of the eight small-effect QTL the DBA/1 alleles are the arthritis-enhancing alleles, while the FVBN alleles are the arthritis-enhancing alleles in the other three QTL, indicating that some susceptibility genes could come from the resistant strain.
T13672	934-937	IN	denotes	For
T13673	991-994	VBP	denotes	are
T13674	938-942	CD	denotes	five
T13675	950-955	CD	denotes	eight
T13676	943-945	IN	denotes	of
T13677	946-949	DT	denotes	the
T13678	969-972	NNS	denotes	QTL
T13679	956-961	JJ	denotes	small
T13680	962-968	NN	denotes	effect
T13681	961-962	HYPH	denotes	-
T13682	973-976	DT	denotes	the
T13683	983-990	NNS	denotes	alleles
T13684	977-980	NN	denotes	DBA
T13685	980-981	HYPH	denotes	/
T13686	981-982	CD	denotes	1
T13687	995-998	DT	denotes	the
T13688	1019-1026	NNS	denotes	alleles
T13689	999-1008	NN	denotes	arthritis
T13690	1009-1018	VBG	denotes	enhancing
T13691	1008-1009	HYPH	denotes	-
T13692	1026-1028	,	denotes	,
T13693	1028-1033	IN	denotes	while
T13694	1051-1054	VBP	denotes	are
T13695	1034-1037	DT	denotes	the
T13696	1043-1050	NNS	denotes	alleles
T13697	1038-1042	NN	denotes	FVBN
T13698	1055-1058	DT	denotes	the
T13699	1079-1086	NNS	denotes	alleles
T13700	1059-1068	NN	denotes	arthritis
T13701	1069-1078	VBG	denotes	enhancing
T13702	1068-1069	HYPH	denotes	-
T13703	1087-1089	IN	denotes	in
T13704	1090-1093	DT	denotes	the
T13705	1106-1109	NNS	denotes	QTL
T13706	1094-1099	JJ	denotes	other
T13707	1100-1105	CD	denotes	three
T13708	1109-1111	,	denotes	,
T13709	1111-1121	VBG	denotes	indicating
T13710	1122-1126	IN	denotes	that
T13711	1159-1163	VB	denotes	come
T13712	1127-1131	DT	denotes	some
T13713	1147-1152	NNS	denotes	genes
T13714	1132-1146	NN	denotes	susceptibility
T13715	1153-1158	MD	denotes	could
T13716	1164-1168	IN	denotes	from
T13717	1169-1172	DT	denotes	the
T13718	1183-1189	NN	denotes	strain
T13719	1173-1182	JJ	denotes	resistant
T13720	1189-1190	.	denotes	.
T13721	1190-1313	sentence	denotes	Interestingly, loci 2 and 7 partially overlap with two arthritis-related QTL identified by us in the same F2 progeny [10].
T13722	1191-1204	RB	denotes	Interestingly
T13723	1229-1236	VBP	denotes	overlap
T13724	1204-1206	,	denotes	,
T13725	1206-1210	NNS	denotes	loci
T13726	1211-1212	CD	denotes	2
T13727	1213-1216	CC	denotes	and
T13728	1217-1218	CD	denotes	7
T13729	1219-1228	RB	denotes	partially
T13730	1237-1241	IN	denotes	with
T13731	1242-1245	CD	denotes	two
T13732	1264-1267	NNS	denotes	QTL
T13733	1246-1255	NN	denotes	arthritis
T13734	1256-1263	VBN	denotes	related
T13735	1255-1256	HYPH	denotes	-
T13736	1268-1278	VBN	denotes	identified
T13737	1279-1281	IN	denotes	by
T13738	1282-1284	PRP	denotes	us
T13739	1285-1287	IN	denotes	in
T13740	1288-1291	DT	denotes	the
T13741	1300-1307	NN	denotes	progeny
T13742	1292-1296	JJ	denotes	same
T13743	1297-1299	NN	denotes	F2
T13744	1308-1309	-LRB-	denotes	[
T13745	1309-1311	CD	denotes	10
T13746	1311-1312	-RRB-	denotes	]
T13747	1312-1313	.	denotes	.
T13748	1313-1426	sentence	denotes	Locus 2 was located at the same genomic region as Cia27, a QTL controlling IgG2a antibody levels to collagen II.
T13749	1314-1319	NN	denotes	Locus
T13750	1326-1333	VBN	denotes	located
T13751	1320-1321	CD	denotes	2
T13752	1322-1325	VBD	denotes	was
T13753	1334-1336	IN	denotes	at
T13754	1337-1340	DT	denotes	the
T13755	1354-1360	NN	denotes	region
T13756	1341-1345	JJ	denotes	same
T13757	1346-1353	JJ	denotes	genomic
T13758	1361-1363	IN	denotes	as
T13759	1364-1369	NN	denotes	Cia27
T13760	1369-1371	,	denotes	,
T13761	1371-1372	DT	denotes	a
T13762	1373-1376	NN	denotes	QTL
T13763	1377-1388	VBG	denotes	controlling
T13764	1389-1394	NN	denotes	IgG2a
T13765	1404-1410	NNS	denotes	levels
T13766	1395-1403	NN	denotes	antibody
T13767	1411-1413	IN	denotes	to
T13768	1414-1422	NN	denotes	collagen
T13769	1423-1425	CD	denotes	II
T13770	1425-1426	.	denotes	.
T13771	1426-1617	sentence	denotes	Recently, we have refined this QTL into a 4.1 Mb genomic region and showed that a gene within this region regulates CIA severity by controlling the IgG2a antibody levels to collagen II [31].
T13772	1427-1435	RB	denotes	Recently
T13773	1445-1452	VBN	denotes	refined
T13774	1435-1437	,	denotes	,
T13775	1437-1439	PRP	denotes	we
T13776	1440-1444	VBP	denotes	have
T13777	1453-1457	DT	denotes	this
T13778	1458-1461	NN	denotes	QTL
T13779	1462-1466	IN	denotes	into
T13780	1467-1468	DT	denotes	a
T13781	1484-1490	NN	denotes	region
T13782	1469-1472	CD	denotes	4.1
T13783	1473-1475	NN	denotes	Mb
T13784	1476-1483	JJ	denotes	genomic
T13785	1491-1494	CC	denotes	and
T13786	1495-1501	VBD	denotes	showed
T13787	1502-1506	IN	denotes	that
T13788	1533-1542	VBZ	denotes	regulates
T13789	1507-1508	DT	denotes	a
T13790	1509-1513	NN	denotes	gene
T13791	1514-1520	IN	denotes	within
T13792	1521-1525	DT	denotes	this
T13793	1526-1532	NN	denotes	region
T13794	1543-1546	NN	denotes	CIA
T13795	1547-1555	NN	denotes	severity
T13796	1556-1558	IN	denotes	by
T13797	1559-1570	VBG	denotes	controlling
T13798	1571-1574	DT	denotes	the
T13799	1590-1596	NNS	denotes	levels
T13800	1575-1580	NN	denotes	IgG2a
T13801	1581-1589	NN	denotes	antibody
T13802	1597-1599	IN	denotes	to
T13803	1600-1608	NN	denotes	collagen
T13804	1609-1611	CD	denotes	II
T13805	1612-1613	-LRB-	denotes	[
T13806	1613-1615	CD	denotes	31
T13807	1615-1616	-RRB-	denotes	]
T13808	1616-1617	.	denotes	.
T13809	1617-1702	sentence	denotes	Locus 7 on chromosome 16 overlaps with Lp1, which controls lymphocyte proliferation.
T13810	1618-1623	NN	denotes	Locus
T13811	1643-1651	VBZ	denotes	overlaps
T13812	1624-1625	CD	denotes	7
T13813	1626-1628	IN	denotes	on
T13814	1629-1639	NN	denotes	chromosome
T13815	1640-1642	CD	denotes	16
T13816	1652-1656	IN	denotes	with
T13817	1657-1660	NN	denotes	Lp1
T13818	1660-1662	,	denotes	,
T13819	1662-1667	WDT	denotes	which
T13820	1668-1676	VBZ	denotes	controls
T13821	1677-1687	NN	denotes	lymphocyte
T13822	1688-1701	NN	denotes	proliferation
T13823	1701-1702	.	denotes	.
T13824	1702-1831	sentence	denotes	Furthermore, according to our unpublished data, loci 8 on chromosome 17 controls lymphocyte adherence during development of CIA.
T13825	1703-1714	RB	denotes	Furthermore
T13826	1775-1783	VBZ	denotes	controls
T13827	1714-1716	,	denotes	,
T13828	1716-1725	VBG	denotes	according
T13829	1726-1728	IN	denotes	to
T13830	1729-1732	PRP$	denotes	our
T13831	1745-1749	NNS	denotes	data
T13832	1733-1744	JJ	denotes	unpublished
T13833	1749-1751	,	denotes	,
T13834	1751-1755	NNS	denotes	loci
T13835	1756-1757	CD	denotes	8
T13836	1758-1760	IN	denotes	on
T13837	1761-1771	NN	denotes	chromosome
T13838	1772-1774	CD	denotes	17
T13839	1784-1794	NN	denotes	lymphocyte
T13840	1795-1804	NN	denotes	adherence
T13841	1805-1811	IN	denotes	during
T13842	1812-1823	NN	denotes	development
T13843	1824-1826	IN	denotes	of
T13844	1827-1830	NN	denotes	CIA
T13845	1830-1831	.	denotes	.
T13846	1831-1955	sentence	denotes	Therefore, the gene within the small-effect QTL could affect CIA severity through controlling arthritis-related phenotypes.
T13847	1832-1841	RB	denotes	Therefore
T13848	1886-1892	VB	denotes	affect
T13849	1841-1843	,	denotes	,
T13850	1843-1846	DT	denotes	the
T13851	1847-1851	NN	denotes	gene
T13852	1852-1858	IN	denotes	within
T13853	1859-1862	DT	denotes	the
T13854	1876-1879	NNS	denotes	QTL
T13855	1863-1868	JJ	denotes	small
T13856	1869-1875	NN	denotes	effect
T13857	1868-1869	HYPH	denotes	-
T13858	1880-1885	MD	denotes	could
T13859	1893-1896	NN	denotes	CIA
T13860	1897-1905	NN	denotes	severity
T13861	1906-1913	IN	denotes	through
T13862	1914-1925	VBG	denotes	controlling
T13863	1926-1935	NN	denotes	arthritis
T13864	1936-1943	VBN	denotes	related
T13865	1935-1936	HYPH	denotes	-
T13866	1944-1954	NNS	denotes	phenotypes
T13867	1954-1955	.	denotes	.
T13868	1955-2092	sentence	denotes	Several studies have been carried out to detect gene expression during CIA, all of which used joints as the target tissue [15,16,21,22].
T13869	1956-1963	JJ	denotes	Several
T13870	1964-1971	NNS	denotes	studies
T13871	1982-1989	VBN	denotes	carried
T13872	1972-1976	VBP	denotes	have
T13873	1977-1981	VBN	denotes	been
T13874	1990-1993	RP	denotes	out
T13875	1994-1996	TO	denotes	to
T13876	1997-2003	VB	denotes	detect
T13877	2004-2008	NN	denotes	gene
T13878	2009-2019	NN	denotes	expression
T13879	2020-2026	IN	denotes	during
T13880	2027-2030	NN	denotes	CIA
T13881	2030-2032	,	denotes	,
T13882	2032-2035	DT	denotes	all
T13883	2045-2049	VBD	denotes	used
T13884	2036-2038	IN	denotes	of
T13885	2039-2044	WDT	denotes	which
T13886	2050-2056	NNS	denotes	joints
T13887	2057-2059	IN	denotes	as
T13888	2060-2063	DT	denotes	the
T13889	2071-2077	NN	denotes	tissue
T13890	2064-2070	NN	denotes	target
T13891	2078-2079	-LRB-	denotes	[
T13892	2088-2090	CD	denotes	22
T13893	2079-2081	CD	denotes	15
T13894	2081-2082	,	denotes	,
T13895	2082-2084	CD	denotes	16
T13896	2084-2085	,	denotes	,
T13897	2085-2087	CD	denotes	21
T13898	2087-2088	,	denotes	,
T13899	2090-2091	-RRB-	denotes	]
T13900	2091-2092	.	denotes	.
T13901	2092-2168	sentence	denotes	This study, for the first time, detected gene expression in LNs during CIA.
T13902	2093-2097	DT	denotes	This
T13903	2098-2103	NN	denotes	study
T13904	2125-2133	VBD	denotes	detected
T13905	2103-2105	,	denotes	,
T13906	2105-2108	IN	denotes	for
T13907	2109-2112	DT	denotes	the
T13908	2119-2123	NN	denotes	time
T13909	2113-2118	JJ	denotes	first
T13910	2123-2125	,	denotes	,
T13911	2134-2138	NN	denotes	gene
T13912	2139-2149	NN	denotes	expression
T13913	2150-2152	IN	denotes	in
T13914	2153-2156	NNS	denotes	LNs
T13915	2157-2163	IN	denotes	during
T13916	2164-2167	NN	denotes	CIA
T13917	2167-2168	.	denotes	.
T13918	2168-2320	sentence	denotes	We present an extensive study of gene expression patterns in LNs of both genetically susceptible and resistant strains at four different phases of CIA.
T13919	2169-2171	PRP	denotes	We
T13920	2172-2179	VBP	denotes	present
T13921	2180-2182	DT	denotes	an
T13922	2193-2198	NN	denotes	study
T13923	2183-2192	JJ	denotes	extensive
T13924	2199-2201	IN	denotes	of
T13925	2202-2206	NN	denotes	gene
T13926	2218-2226	NNS	denotes	patterns
T13927	2207-2217	NN	denotes	expression
T13928	2227-2229	IN	denotes	in
T13929	2230-2233	NNS	denotes	LNs
T13930	2234-2236	IN	denotes	of
T13931	2237-2241	CC	denotes	both
T13932	2280-2287	NNS	denotes	strains
T13933	2242-2253	RB	denotes	genetically
T13934	2254-2265	JJ	denotes	susceptible
T13935	2266-2269	CC	denotes	and
T13936	2270-2279	JJ	denotes	resistant
T13937	2288-2290	IN	denotes	at
T13938	2291-2295	CD	denotes	four
T13939	2306-2312	NNS	denotes	phases
T13940	2296-2305	JJ	denotes	different
T13941	2313-2315	IN	denotes	of
T13942	2316-2319	NN	denotes	CIA
T13943	2319-2320	.	denotes	.
T13944	2320-2505	sentence	denotes	In both strains, differentially regulated genes were highly concentrated at the PI and CA phases, and only a small number of genes were differentially expressed in two or three phases.
T13945	2321-2323	IN	denotes	In
T13946	2369-2373	VBD	denotes	were
T13947	2324-2328	DT	denotes	both
T13948	2329-2336	NNS	denotes	strains
T13949	2336-2338	,	denotes	,
T13950	2338-2352	RB	denotes	differentially
T13951	2353-2362	VBN	denotes	regulated
T13952	2363-2368	NNS	denotes	genes
T13953	2374-2380	RB	denotes	highly
T13954	2381-2393	JJ	denotes	concentrated
T13955	2394-2396	IN	denotes	at
T13956	2397-2400	DT	denotes	the
T13957	2411-2417	NNS	denotes	phases
T13958	2401-2403	NN	denotes	PI
T13959	2404-2407	CC	denotes	and
T13960	2408-2410	NN	denotes	CA
T13961	2417-2419	,	denotes	,
T13962	2419-2422	CC	denotes	and
T13963	2423-2427	RB	denotes	only
T13964	2436-2442	NN	denotes	number
T13965	2428-2429	DT	denotes	a
T13966	2430-2435	JJ	denotes	small
T13967	2472-2481	VBN	denotes	expressed
T13968	2443-2445	IN	denotes	of
T13969	2446-2451	NNS	denotes	genes
T13970	2452-2456	VBD	denotes	were
T13971	2457-2471	RB	denotes	differentially
T13972	2482-2484	IN	denotes	in
T13973	2485-2488	CD	denotes	two
T13974	2498-2504	NNS	denotes	phases
T13975	2489-2491	CC	denotes	or
T13976	2492-2497	CD	denotes	three
T13977	2504-2505	.	denotes	.
T13978	2505-2667	sentence	denotes	This indicates that biological responses in LNs were stronger in the PI and CA phases than in the OA phase, and the responses at different phases were different.
T13979	2506-2510	DT	denotes	This
T13980	2511-2520	VBZ	denotes	indicates
T13981	2521-2525	IN	denotes	that
T13982	2554-2558	VBD	denotes	were
T13983	2526-2536	JJ	denotes	biological
T13984	2537-2546	NNS	denotes	responses
T13985	2547-2549	IN	denotes	in
T13986	2550-2553	NNS	denotes	LNs
T13987	2559-2567	JJR	denotes	stronger
T13988	2568-2570	IN	denotes	in
T13989	2571-2574	DT	denotes	the
T13990	2585-2591	NNS	denotes	phases
T13991	2575-2577	NN	denotes	PI
T13992	2578-2581	CC	denotes	and
T13993	2582-2584	NN	denotes	CA
T13994	2592-2596	IN	denotes	than
T13995	2597-2599	IN	denotes	in
T13996	2600-2603	DT	denotes	the
T13997	2607-2612	NN	denotes	phase
T13998	2604-2606	NN	denotes	OA
T13999	2612-2614	,	denotes	,
T14000	2614-2617	CC	denotes	and
T14001	2618-2621	DT	denotes	the
T14002	2622-2631	NNS	denotes	responses
T14003	2652-2656	VBD	denotes	were
T14004	2632-2634	IN	denotes	at
T14005	2635-2644	JJ	denotes	different
T14006	2645-2651	NNS	denotes	phases
T14007	2657-2666	JJ	denotes	different
T14008	2666-2667	.	denotes	.
T14009	2667-2804	sentence	denotes	When comparing the susceptible to the resistant strain, the biggest difference was found in one cluster of genes (cluster IV, Figure 2).
T14010	2668-2672	WRB	denotes	When
T14011	2673-2682	VBG	denotes	comparing
T14012	2751-2756	VBN	denotes	found
T14013	2683-2686	DT	denotes	the
T14014	2687-2698	JJ	denotes	susceptible
T14015	2699-2701	IN	denotes	to
T14016	2702-2705	DT	denotes	the
T14017	2706-2715	JJ	denotes	resistant
T14018	2716-2722	NN	denotes	strain
T14019	2722-2724	,	denotes	,
T14020	2724-2727	DT	denotes	the
T14021	2736-2746	NN	denotes	difference
T14022	2728-2735	JJS	denotes	biggest
T14023	2747-2750	VBD	denotes	was
T14024	2757-2759	IN	denotes	in
T14025	2760-2763	CD	denotes	one
T14026	2764-2771	NN	denotes	cluster
T14027	2772-2774	IN	denotes	of
T14028	2775-2780	NNS	denotes	genes
T14029	2781-2782	-LRB-	denotes	(
T14030	2782-2789	NN	denotes	cluster
T14031	2790-2792	CD	denotes	IV
T14032	2792-2794	,	denotes	,
T14033	2794-2800	NN	denotes	Figure
T14034	2801-2802	CD	denotes	2
T14035	2802-2803	-RRB-	denotes	)
T14036	2803-2804	.	denotes	.
T14037	2804-2959	sentence	denotes	These genes had a higher expression in DBA/1 than in FVB/N at the early phases of CIA (NC, PI and OA) and the opposite expression pattern in the CA phase.
T14038	2805-2810	DT	denotes	These
T14039	2811-2816	NNS	denotes	genes
T14040	2817-2820	VBD	denotes	had
T14041	2821-2822	DT	denotes	a
T14042	2830-2840	NN	denotes	expression
T14043	2823-2829	JJR	denotes	higher
T14044	2841-2843	IN	denotes	in
T14045	2844-2847	NN	denotes	DBA
T14046	2847-2848	HYPH	denotes	/
T14047	2848-2849	CD	denotes	1
T14048	2850-2854	IN	denotes	than
T14049	2855-2857	IN	denotes	in
T14050	2858-2861	NN	denotes	FVB
T14051	2862-2863	NN	denotes	N
T14052	2861-2862	HYPH	denotes	/
T14053	2864-2866	IN	denotes	at
T14054	2867-2870	DT	denotes	the
T14055	2877-2883	NNS	denotes	phases
T14056	2871-2876	JJ	denotes	early
T14057	2884-2886	IN	denotes	of
T14058	2887-2890	NN	denotes	CIA
T14059	2891-2892	-LRB-	denotes	(
T14060	2892-2894	NN	denotes	NC
T14061	2894-2896	,	denotes	,
T14062	2896-2898	NN	denotes	PI
T14063	2899-2902	CC	denotes	and
T14064	2903-2905	NN	denotes	OA
T14065	2905-2906	-RRB-	denotes	)
T14066	2907-2910	CC	denotes	and
T14067	2911-2914	DT	denotes	the
T14068	2935-2942	NN	denotes	pattern
T14069	2915-2923	JJ	denotes	opposite
T14070	2924-2934	NN	denotes	expression
T14071	2943-2945	IN	denotes	in
T14072	2946-2949	DT	denotes	the
T14073	2953-2958	NN	denotes	phase
T14074	2950-2952	NN	denotes	CA
T14075	2958-2959	.	denotes	.
T14076	2959-3164	sentence	denotes	GO term classification revealed that these genes were related to lymphocyte proliferation and activation, suggesting that lymphocytes in the DBA/1 strain are more activated than those in the FVB/N strain.
T14077	2960-2962	NN	denotes	GO
T14078	2968-2982	NN	denotes	classification
T14079	2963-2967	NN	denotes	term
T14080	2983-2991	VBD	denotes	revealed
T14081	2992-2996	IN	denotes	that
T14082	3014-3021	VBN	denotes	related
T14083	2997-3002	DT	denotes	these
T14084	3003-3008	NNS	denotes	genes
T14085	3009-3013	VBD	denotes	were
T14086	3022-3024	IN	denotes	to
T14087	3025-3035	NN	denotes	lymphocyte
T14088	3036-3049	NN	denotes	proliferation
T14089	3050-3053	CC	denotes	and
T14090	3054-3064	NN	denotes	activation
T14091	3064-3066	,	denotes	,
T14092	3066-3076	VBG	denotes	suggesting
T14093	3077-3081	IN	denotes	that
T14094	3114-3117	VBP	denotes	are
T14095	3082-3093	NNS	denotes	lymphocytes
T14096	3094-3096	IN	denotes	in
T14097	3097-3100	DT	denotes	the
T14098	3107-3113	NN	denotes	strain
T14099	3101-3104	NN	denotes	DBA
T14100	3104-3105	HYPH	denotes	/
T14101	3105-3106	CD	denotes	1
T14102	3118-3122	RBR	denotes	more
T14103	3123-3132	JJ	denotes	activated
T14104	3133-3137	IN	denotes	than
T14105	3138-3143	DT	denotes	those
T14106	3144-3146	IN	denotes	in
T14107	3147-3150	DT	denotes	the
T14108	3157-3163	NN	denotes	strain
T14109	3151-3154	NN	denotes	FVB
T14110	3155-3156	NN	denotes	N
T14111	3154-3155	HYPH	denotes	/
T14112	3163-3164	.	denotes	.
T14113	3164-3305	sentence	denotes	However, this difference is not CIA specific because the expression difference between the two strains existed in mice without immunisation.
T14114	3165-3172	RB	denotes	However
T14115	3190-3192	VBZ	denotes	is
T14116	3172-3174	,	denotes	,
T14117	3174-3178	DT	denotes	this
T14118	3179-3189	NN	denotes	difference
T14119	3193-3196	RB	denotes	not
T14120	3197-3200	NN	denotes	CIA
T14121	3201-3209	JJ	denotes	specific
T14122	3210-3217	IN	denotes	because
T14123	3268-3275	VBD	denotes	existed
T14124	3218-3221	DT	denotes	the
T14125	3233-3243	NN	denotes	difference
T14126	3222-3232	NN	denotes	expression
T14127	3244-3251	IN	denotes	between
T14128	3252-3255	DT	denotes	the
T14129	3260-3267	NNS	denotes	strains
T14130	3256-3259	CD	denotes	two
T14131	3276-3278	IN	denotes	in
T14132	3279-3283	NNS	denotes	mice
T14133	3284-3291	IN	denotes	without
T14134	3292-3304	NN	denotes	immunisation
T14135	3304-3305	.	denotes	.
T14136	3305-3438	sentence	denotes	Additionally, some genes related to the immune response were upregulated in the DBA/1 strain but not in the FVB/N strain during CIA.
T14137	3306-3318	RB	denotes	Additionally
T14138	3367-3378	VBN	denotes	upregulated
T14139	3318-3320	,	denotes	,
T14140	3320-3324	DT	denotes	some
T14141	3325-3330	NNS	denotes	genes
T14142	3331-3338	VBN	denotes	related
T14143	3339-3341	IN	denotes	to
T14144	3342-3345	DT	denotes	the
T14145	3353-3361	NN	denotes	response
T14146	3346-3352	JJ	denotes	immune
T14147	3362-3366	VBD	denotes	were
T14148	3379-3381	IN	denotes	in
T14149	3382-3385	DT	denotes	the
T14150	3392-3398	NN	denotes	strain
T14151	3386-3389	NN	denotes	DBA
T14152	3389-3390	HYPH	denotes	/
T14153	3390-3391	CD	denotes	1
T14154	3399-3402	CC	denotes	but
T14155	3403-3406	RB	denotes	not
T14156	3407-3409	IN	denotes	in
T14157	3410-3413	DT	denotes	the
T14158	3420-3426	NN	denotes	strain
T14159	3414-3417	NN	denotes	FVB
T14160	3418-3419	NN	denotes	N
T14161	3417-3418	HYPH	denotes	/
T14162	3427-3433	IN	denotes	during
T14163	3434-3437	NN	denotes	CIA
T14164	3437-3438	.	denotes	.
T14165	3438-3669	sentence	denotes	These differences could explain why a higher antibody response to collagen II occurred in the DBA/1 strain compared to the FVB/N strain, and might partially explain the difference of the susceptibility to CIA between both strains.
T14166	3439-3444	DT	denotes	These
T14167	3445-3456	NNS	denotes	differences
T14168	3463-3470	VB	denotes	explain
T14169	3457-3462	MD	denotes	could
T14170	3471-3474	WRB	denotes	why
T14171	3517-3525	VBD	denotes	occurred
T14172	3475-3476	DT	denotes	a
T14173	3493-3501	NN	denotes	response
T14174	3477-3483	JJR	denotes	higher
T14175	3484-3492	NN	denotes	antibody
T14176	3502-3504	IN	denotes	to
T14177	3505-3513	NN	denotes	collagen
T14178	3514-3516	CD	denotes	II
T14179	3526-3528	IN	denotes	in
T14180	3529-3532	DT	denotes	the
T14181	3539-3545	NN	denotes	strain
T14182	3533-3536	NN	denotes	DBA
T14183	3536-3537	HYPH	denotes	/
T14184	3537-3538	CD	denotes	1
T14185	3546-3554	VBN	denotes	compared
T14186	3555-3557	IN	denotes	to
T14187	3558-3561	DT	denotes	the
T14188	3568-3574	NN	denotes	strain
T14189	3562-3565	NN	denotes	FVB
T14190	3566-3567	NN	denotes	N
T14191	3565-3566	HYPH	denotes	/
T14192	3574-3576	,	denotes	,
T14193	3576-3579	CC	denotes	and
T14194	3580-3585	MD	denotes	might
T14195	3596-3603	VB	denotes	explain
T14196	3586-3595	RB	denotes	partially
T14197	3604-3607	DT	denotes	the
T14198	3608-3618	NN	denotes	difference
T14199	3619-3621	IN	denotes	of
T14200	3622-3625	DT	denotes	the
T14201	3626-3640	NN	denotes	susceptibility
T14202	3641-3643	IN	denotes	to
T14203	3644-3647	NN	denotes	CIA
T14204	3648-3655	IN	denotes	between
T14205	3656-3660	DT	denotes	both
T14206	3661-3668	NNS	denotes	strains
T14207	3668-3669	.	denotes	.
T14208	3669-3853	sentence	denotes	Twenty-one genes were identified as potential candidate genes for six of the eight small-effect QTL according to their gene expression patterns during CIA and their genomic locations.
T14209	3670-3676	CD	denotes	Twenty
T14210	3677-3680	CD	denotes	one
T14211	3676-3677	HYPH	denotes	-
T14212	3681-3686	NNS	denotes	genes
T14213	3692-3702	VBN	denotes	identified
T14214	3687-3691	VBD	denotes	were
T14215	3703-3705	IN	denotes	as
T14216	3706-3715	JJ	denotes	potential
T14217	3726-3731	NNS	denotes	genes
T14218	3716-3725	NN	denotes	candidate
T14219	3732-3735	IN	denotes	for
T14220	3736-3739	CD	denotes	six
T14221	3747-3752	CD	denotes	eight
T14222	3740-3742	IN	denotes	of
T14223	3743-3746	DT	denotes	the
T14224	3766-3769	NNS	denotes	QTL
T14225	3753-3758	JJ	denotes	small
T14226	3759-3765	NN	denotes	effect
T14227	3758-3759	HYPH	denotes	-
T14228	3770-3779	VBG	denotes	according
T14229	3780-3782	IN	denotes	to
T14230	3783-3788	PRP$	denotes	their
T14231	3805-3813	NNS	denotes	patterns
T14232	3789-3793	NN	denotes	gene
T14233	3794-3804	NN	denotes	expression
T14234	3814-3820	IN	denotes	during
T14235	3821-3824	NN	denotes	CIA
T14236	3825-3828	CC	denotes	and
T14237	3829-3834	PRP$	denotes	their
T14238	3843-3852	NNS	denotes	locations
T14239	3835-3842	JJ	denotes	genomic
T14240	3852-3853	.	denotes	.
T14241	3853-4046	sentence	denotes	No candidate genes were located in QTL 4 and 7, suggesting that QTG polymorphisms of the susceptibility genes inside these two QTL might not affect the phenotype by regulating gene expression.
T14242	3854-3856	DT	denotes	No
T14243	3867-3872	NNS	denotes	genes
T14244	3857-3866	NN	denotes	candidate
T14245	3878-3885	VBN	denotes	located
T14246	3873-3877	VBD	denotes	were
T14247	3886-3888	IN	denotes	in
T14248	3889-3892	NNS	denotes	QTL
T14249	3893-3894	CD	denotes	4
T14250	3895-3898	CC	denotes	and
T14251	3899-3900	CD	denotes	7
T14252	3900-3902	,	denotes	,
T14253	3902-3912	VBG	denotes	suggesting
T14254	3913-3917	IN	denotes	that
T14255	3995-4001	VB	denotes	affect
T14256	3918-3921	NN	denotes	QTG
T14257	3922-3935	NNS	denotes	polymorphisms
T14258	3936-3938	IN	denotes	of
T14259	3939-3942	DT	denotes	the
T14260	3958-3963	NNS	denotes	genes
T14261	3943-3957	NN	denotes	susceptibility
T14262	3964-3970	IN	denotes	inside
T14263	3971-3976	DT	denotes	these
T14264	3981-3984	NNS	denotes	QTL
T14265	3977-3980	CD	denotes	two
T14266	3985-3990	MD	denotes	might
T14267	3991-3994	RB	denotes	not
T14268	4002-4005	DT	denotes	the
T14269	4006-4015	NN	denotes	phenotype
T14270	4016-4018	IN	denotes	by
T14271	4019-4029	VBG	denotes	regulating
T14272	4030-4034	NN	denotes	gene
T14273	4035-4045	NN	denotes	expression
T14274	4045-4046	.	denotes	.
T14275	4046-4119	sentence	denotes	Two of the 21 candidate genes were reported to be involved in arthritis.
T14276	4047-4050	CD	denotes	Two
T14277	4058-4060	CD	denotes	21
T14278	4051-4053	IN	denotes	of
T14279	4054-4057	DT	denotes	the
T14280	4071-4076	NNS	denotes	genes
T14281	4061-4070	NN	denotes	candidate
T14282	4082-4090	VBN	denotes	reported
T14283	4077-4081	VBD	denotes	were
T14284	4091-4093	TO	denotes	to
T14285	4097-4105	VBN	denotes	involved
T14286	4094-4096	VB	denotes	be
T14287	4106-4108	IN	denotes	in
T14288	4109-4118	NN	denotes	arthritis
T14289	4118-4119	.	denotes	.
T14290	4119-4337	sentence	denotes	Mapk14, a candidate gene for locus 8 and also called p38 mitogen-activated protein kinase (MAPK) alpha, regulates the production of arthritis-essential cytokines, such as tumour necrosis factor and interleukin-1 [32].
T14291	4120-4126	NN	denotes	Mapk14
T14292	4224-4233	VBZ	denotes	regulates
T14293	4126-4128	,	denotes	,
T14294	4128-4129	DT	denotes	a
T14295	4140-4144	NN	denotes	gene
T14296	4130-4139	NN	denotes	candidate
T14297	4145-4148	IN	denotes	for
T14298	4149-4154	NN	denotes	locus
T14299	4155-4156	CD	denotes	8
T14300	4157-4160	CC	denotes	and
T14301	4161-4165	RB	denotes	also
T14302	4166-4172	VBN	denotes	called
T14303	4173-4176	NN	denotes	p38
T14304	4203-4209	NN	denotes	kinase
T14305	4177-4184	NN	denotes	mitogen
T14306	4185-4194	VBN	denotes	activated
T14307	4184-4185	HYPH	denotes	-
T14308	4195-4202	NN	denotes	protein
T14309	4217-4222	NN	denotes	alpha
T14310	4210-4211	-LRB-	denotes	(
T14311	4211-4215	NN	denotes	MAPK
T14312	4215-4216	-RRB-	denotes	)
T14313	4222-4224	,	denotes	,
T14314	4234-4237	DT	denotes	the
T14315	4238-4248	NN	denotes	production
T14316	4249-4251	IN	denotes	of
T14317	4252-4261	NN	denotes	arthritis
T14318	4262-4271	JJ	denotes	essential
T14319	4261-4262	HYPH	denotes	-
T14320	4272-4281	NNS	denotes	cytokines
T14321	4281-4283	,	denotes	,
T14322	4283-4287	JJ	denotes	such
T14323	4288-4290	IN	denotes	as
T14324	4291-4297	NN	denotes	tumour
T14325	4307-4313	NN	denotes	factor
T14326	4298-4306	NN	denotes	necrosis
T14327	4314-4317	CC	denotes	and
T14328	4318-4329	NN	denotes	interleukin
T14329	4329-4330	HYPH	denotes	-
T14330	4330-4331	CD	denotes	1
T14331	4332-4333	-LRB-	denotes	[
T14332	4333-4335	CD	denotes	32
T14333	4335-4336	-RRB-	denotes	]
T14334	4336-4337	.	denotes	.
T14335	4337-4472	sentence	denotes	Moreover, inhibitors of p38 MAPK could attenuate CIA in rats [33], and p38 MAPK is becoming a potential therapeutic target in RA [32].
T14336	4338-4346	RB	denotes	Moreover
T14337	4377-4386	VB	denotes	attenuate
T14338	4346-4348	,	denotes	,
T14339	4348-4358	NNS	denotes	inhibitors
T14340	4359-4361	IN	denotes	of
T14341	4362-4365	NN	denotes	p38
T14342	4366-4370	NN	denotes	MAPK
T14343	4371-4376	MD	denotes	could
T14344	4387-4390	NN	denotes	CIA
T14345	4391-4393	IN	denotes	in
T14346	4394-4398	NNS	denotes	rats
T14347	4399-4400	-LRB-	denotes	[
T14348	4400-4402	CD	denotes	33
T14349	4402-4403	-RRB-	denotes	]
T14350	4403-4405	,	denotes	,
T14351	4405-4408	CC	denotes	and
T14352	4409-4412	NN	denotes	p38
T14353	4413-4417	NN	denotes	MAPK
T14354	4421-4429	VBG	denotes	becoming
T14355	4418-4420	VBZ	denotes	is
T14356	4430-4431	DT	denotes	a
T14357	4454-4460	NN	denotes	target
T14358	4432-4441	JJ	denotes	potential
T14359	4442-4453	JJ	denotes	therapeutic
T14360	4461-4463	IN	denotes	in
T14361	4464-4466	NN	denotes	RA
T14362	4467-4468	-LRB-	denotes	[
T14363	4468-4470	CD	denotes	32
T14364	4470-4471	-RRB-	denotes	]
T14365	4471-4472	.	denotes	.
T14366	4472-4585	sentence	denotes	Stat5a, a candidate gene for loci 6, is an essential molecule for lymphoid development and differentiation [34].
T14367	4473-4479	NN	denotes	Stat5a
T14368	4510-4512	VBZ	denotes	is
T14369	4479-4481	,	denotes	,
T14370	4481-4482	DT	denotes	a
T14371	4493-4497	NN	denotes	gene
T14372	4483-4492	NN	denotes	candidate
T14373	4498-4501	IN	denotes	for
T14374	4502-4506	NNS	denotes	loci
T14375	4507-4508	CD	denotes	6
T14376	4508-4510	,	denotes	,
T14377	4513-4515	DT	denotes	an
T14378	4526-4534	NN	denotes	molecule
T14379	4516-4525	JJ	denotes	essential
T14380	4535-4538	IN	denotes	for
T14381	4539-4547	NN	denotes	lymphoid
T14382	4548-4559	NN	denotes	development
T14383	4560-4563	CC	denotes	and
T14384	4564-4579	NN	denotes	differentiation
T14385	4580-4581	-LRB-	denotes	[
T14386	4581-4583	CD	denotes	34
T14387	4583-4584	-RRB-	denotes	]
T14388	4584-4585	.	denotes	.
T14389	4585-4693	sentence	denotes	Stat5a-deficient mice were reported to lose tolerance, resulting in the development of autoimmune diseases.
T14390	4586-4592	NN	denotes	Stat5a
T14391	4593-4602	JJ	denotes	deficient
T14392	4592-4593	HYPH	denotes	-
T14393	4603-4607	NNS	denotes	mice
T14394	4613-4621	VBN	denotes	reported
T14395	4608-4612	VBD	denotes	were
T14396	4622-4624	TO	denotes	to
T14397	4625-4629	VB	denotes	lose
T14398	4630-4639	NN	denotes	tolerance
T14399	4639-4641	,	denotes	,
T14400	4641-4650	VBG	denotes	resulting
T14401	4651-4653	IN	denotes	in
T14402	4654-4657	DT	denotes	the
T14403	4658-4669	NN	denotes	development
T14404	4670-4672	IN	denotes	of
T14405	4673-4683	JJ	denotes	autoimmune
T14406	4684-4692	NNS	denotes	diseases
T14407	4692-4693	.	denotes	.
T14408	4693-4812	sentence	denotes	Stat5a is suggested to contribute to tolerance through maintenance of the CD4+CD25+ regulatory T cell population [35].
T14409	4694-4700	NN	denotes	Stat5a
T14410	4704-4713	VBN	denotes	suggested
T14411	4701-4703	VBZ	denotes	is
T14412	4714-4716	TO	denotes	to
T14413	4717-4727	VB	denotes	contribute
T14414	4728-4730	IN	denotes	to
T14415	4731-4740	NN	denotes	tolerance
T14416	4741-4748	IN	denotes	through
T14417	4749-4760	NN	denotes	maintenance
T14418	4761-4763	IN	denotes	of
T14419	4764-4767	DT	denotes	the
T14420	4796-4806	NN	denotes	population
T14421	4768-4777	NN	denotes	CD4+CD25+
T14422	4778-4788	JJ	denotes	regulatory
T14423	4789-4790	NN	denotes	T
T14424	4791-4795	NN	denotes	cell
T14425	4807-4808	-LRB-	denotes	[
T14426	4808-4810	CD	denotes	35
T14427	4810-4811	-RRB-	denotes	]
T14428	4811-4812	.	denotes	.
T14429	4812-4935	sentence	denotes	Therefore, we have presented a strategy to identify small-effect QTL and search for potential candidate genes within them.
T14430	4813-4822	RB	denotes	Therefore
T14431	4832-4841	VBN	denotes	presented
T14432	4822-4824	,	denotes	,
T14433	4824-4826	PRP	denotes	we
T14434	4827-4831	VBP	denotes	have
T14435	4842-4843	DT	denotes	a
T14436	4844-4852	NN	denotes	strategy
T14437	4853-4855	TO	denotes	to
T14438	4856-4864	VB	denotes	identify
T14439	4865-4870	JJ	denotes	small
T14440	4871-4877	NN	denotes	effect
T14441	4870-4871	HYPH	denotes	-
T14442	4878-4881	NNS	denotes	QTL
T14443	4882-4885	CC	denotes	and
T14444	4886-4892	VB	denotes	search
T14445	4893-4896	IN	denotes	for
T14446	4897-4906	JJ	denotes	potential
T14447	4917-4922	NNS	denotes	genes
T14448	4907-4916	NN	denotes	candidate
T14449	4923-4929	IN	denotes	within
T14450	4930-4934	PRP	denotes	them
T14451	4934-4935	.	denotes	.
T14452	4935-5077	sentence	denotes	However, it is noteworthy that the low statistical threshold and small number of animals per group could lead to some false positive results.
T14453	4936-4943	RB	denotes	However
T14454	4948-4950	VBZ	denotes	is
T14455	4943-4945	,	denotes	,
T14456	4945-4947	PRP	denotes	it
T14457	4951-4961	JJ	denotes	noteworthy
T14458	4962-4966	IN	denotes	that
T14459	5041-5045	VB	denotes	lead
T14460	4967-4970	DT	denotes	the
T14461	4987-4996	NN	denotes	threshold
T14462	4971-4974	JJ	denotes	low
T14463	4975-4986	JJ	denotes	statistical
T14464	4997-5000	CC	denotes	and
T14465	5001-5006	JJ	denotes	small
T14466	5007-5013	NN	denotes	number
T14467	5014-5016	IN	denotes	of
T14468	5017-5024	NNS	denotes	animals
T14469	5025-5028	IN	denotes	per
T14470	5029-5034	NN	denotes	group
T14471	5035-5040	MD	denotes	could
T14472	5046-5048	IN	denotes	to
T14473	5049-5053	DT	denotes	some
T14474	5069-5076	NNS	denotes	results
T14475	5054-5059	JJ	denotes	false
T14476	5060-5068	JJ	denotes	positive
T14477	5076-5077	.	denotes	.
T14478	5077-5214	sentence	denotes	On the genome level, some of the eight small-effect QTL identified using a very low threshold value (P < 0.05) could be false positives.
T14479	5078-5080	IN	denotes	On
T14480	5195-5197	VB	denotes	be
T14481	5081-5084	DT	denotes	the
T14482	5092-5097	NN	denotes	level
T14483	5085-5091	NN	denotes	genome
T14484	5097-5099	,	denotes	,
T14485	5099-5103	DT	denotes	some
T14486	5104-5106	IN	denotes	of
T14487	5107-5110	DT	denotes	the
T14488	5130-5133	NNS	denotes	QTL
T14489	5111-5116	CD	denotes	eight
T14490	5117-5122	JJ	denotes	small
T14491	5123-5129	NN	denotes	effect
T14492	5122-5123	HYPH	denotes	-
T14493	5134-5144	VBN	denotes	identified
T14494	5145-5150	VBG	denotes	using
T14495	5151-5152	DT	denotes	a
T14496	5172-5177	NN	denotes	value
T14497	5153-5157	RB	denotes	very
T14498	5158-5161	JJ	denotes	low
T14499	5162-5171	NN	denotes	threshold
T14500	5178-5179	-LRB-	denotes	(
T14501	5183-5187	CD	denotes	0.05
T14502	5179-5180	NN	denotes	P
T14503	5181-5182	SYM	denotes	<
T14504	5187-5188	-RRB-	denotes	)
T14505	5189-5194	MD	denotes	could
T14506	5198-5203	JJ	denotes	false
T14507	5204-5213	NNS	denotes	positives
T14508	5213-5214	.	denotes	.
T14509	5214-5336	sentence	denotes	For example, locus 4 was identified with a low P value and does not overlap with any previously identified arthritis QTL.
T14510	5215-5218	IN	denotes	For
T14511	5240-5250	VBN	denotes	identified
T14512	5219-5226	NN	denotes	example
T14513	5226-5228	,	denotes	,
T14514	5228-5233	NN	denotes	locus
T14515	5234-5235	CD	denotes	4
T14516	5236-5239	VBD	denotes	was
T14517	5251-5255	IN	denotes	with
T14518	5256-5257	DT	denotes	a
T14519	5264-5269	NN	denotes	value
T14520	5258-5261	JJ	denotes	low
T14521	5262-5263	NN	denotes	P
T14522	5270-5273	CC	denotes	and
T14523	5274-5278	VBZ	denotes	does
T14524	5283-5290	VB	denotes	overlap
T14525	5279-5282	RB	denotes	not
T14526	5291-5295	IN	denotes	with
T14527	5296-5299	DT	denotes	any
T14528	5332-5335	NNS	denotes	QTL
T14529	5300-5310	RB	denotes	previously
T14530	5311-5321	VBN	denotes	identified
T14531	5322-5331	NN	denotes	arthritis
T14532	5335-5336	.	denotes	.
T14533	5336-5531	sentence	denotes	On the transcriptome level, the small number of animals per group and the low threshold used to detect gene expression could also result in false positives in the differentially expressed genes.
T14534	5337-5339	IN	denotes	On
T14535	5467-5473	VB	denotes	result
T14536	5340-5343	DT	denotes	the
T14537	5358-5363	NN	denotes	level
T14538	5344-5357	NN	denotes	transcriptome
T14539	5363-5365	,	denotes	,
T14540	5365-5368	DT	denotes	the
T14541	5375-5381	NN	denotes	number
T14542	5369-5374	JJ	denotes	small
T14543	5382-5384	IN	denotes	of
T14544	5385-5392	NNS	denotes	animals
T14545	5393-5396	IN	denotes	per
T14546	5397-5402	NN	denotes	group
T14578	5596-5599	RB	denotes	not
T14579	5605-5609	IN	denotes	from
T14580	5600-5604	RB	denotes	only
T14581	5610-5616	NN	denotes	allele
T14582	5617-5627	NN	denotes	difference
T14583	5628-5635	IN	denotes	between
T14584	5636-5639	CD	denotes	two
T14585	5640-5647	NNS	denotes	strains
T14586	5647-5649	,	denotes	,
T14587	5649-5652	CC	denotes	but
T14588	5653-5657	RB	denotes	also
T14589	5658-5662	IN	denotes	from
T14590	5663-5668	JJ	denotes	other
T14591	5669-5676	NNS	denotes	factors
T14592	5676-5677	.	denotes	.
T14593	5677-5740	sentence	denotes	Therefore, our findings should be confirmed in future studies.
T14594	5678-5687	RB	denotes	Therefore
T14595	5712-5721	VBN	denotes	confirmed
T14596	5687-5689	,	denotes	,
T14597	5689-5692	PRP$	denotes	our
T14598	5693-5701	NNS	denotes	findings
T14599	5702-5708	MD	denotes	should
T14600	5709-5711	VB	denotes	be
T14601	5722-5724	IN	denotes	in
T14602	5725-5731	JJ	denotes	future
T14603	5732-5739	NNS	denotes	studies
T14604	5739-5740	.	denotes	.
T14547	5403-5406	CC	denotes	and
T14548	5407-5410	DT	denotes	the
T14549	5415-5424	NN	denotes	threshold
T14550	5411-5414	JJ	denotes	low
T14551	5425-5429	VBN	denotes	used
T14552	5430-5432	TO	denotes	to
T14553	5433-5439	VB	denotes	detect
T14554	5440-5444	NN	denotes	gene
T14555	5445-5455	NN	denotes	expression
T14556	5456-5461	MD	denotes	could
T14557	5462-5466	RB	denotes	also
T14558	5474-5476	IN	denotes	in
T14559	5477-5482	JJ	denotes	false
T14560	5483-5492	NNS	denotes	positives
T14561	5493-5495	IN	denotes	in
T14562	5496-5499	DT	denotes	the
T14563	5525-5530	NNS	denotes	genes
T14564	5500-5514	RB	denotes	differentially
T14565	5515-5524	VBN	denotes	expressed
T14566	5530-5531	.	denotes	.
T14567	5531-5677	sentence	denotes	Furthermore, the differential expression of a gene could result not only from allele difference between two strains, but also from other factors.
T14568	5532-5543	RB	denotes	Furthermore
T14569	5589-5595	VB	denotes	result
T14570	5543-5545	,	denotes	,
T14571	5545-5548	DT	denotes	the
T14572	5562-5572	NN	denotes	expression
T14573	5549-5561	JJ	denotes	differential
T14574	5573-5575	IN	denotes	of
T14575	5576-5577	DT	denotes	a
T14576	5578-5582	NN	denotes	gene
T14577	5583-5588	MD	denotes	could
R3525	T13481	T13482	prep	In,attempted
R3526	T13483	T13484	det	this,study
R3527	T13484	T13481	pobj	study,In
R3528	T13485	T13482	punct	", ",attempted
R3529	T13486	T13482	nsubj	we,attempted
R3530	T13487	T13482	prep	for,attempted
R3531	T13488	T13489	det	the,time
R3532	T13489	T13487	pobj	time,for
R3533	T13490	T13489	amod	first,time
R3534	T13491	T13492	aux	to,identify
R3535	T13492	T13482	xcomp	identify,attempted
R3536	T13493	T13494	amod	small,effect
R3537	T13494	T13496	compound	effect,QTL
R3538	T13495	T13494	punct	-,effect
R3539	T13496	T13492	dobj	QTL,identify
R3540	T13497	T13492	prep	in,identify
R3541	T13498	T13499	det	an,progeny
R3542	T13499	T13497	pobj	progeny,in
R3543	T13500	T13499	compound	F2,progeny
R3544	T13501	T13482	punct	.,attempted
R3545	T13503	T13504	amod	Small,effect
R3546	T13504	T13506	compound	effect,QTL
R3547	T13505	T13504	punct	-,effect
R3548	T13506	T13507	nsubjpass	QTL,defined
R3549	T13508	T13507	auxpass	are,defined
R3550	T13509	T13507	prep	as,defined
R3551	T13510	T13509	pobj	those,as
R3552	T13511	T13510	acl	reaching,those
R3553	T13512	T13513	det	the,value
R3554	T13513	T13511	dobj	value,reaching
R3555	T13514	T13513	compound	threshold,value
R3556	T13515	T13513	prep	of,value
R3557	T13516	T13517	nsubj	P,0.05
R3558	T13517	T13515	pcomp	0.05,of
R3559	T13518	T13517	punct	=,0.05
R3560	T13519	T13507	cc	but,defined
R3561	T13520	T13521	nsubj	that,reach
R3562	T13521	T13507	conj	reach,defined
R3563	T13522	T13521	aux	did,reach
R3564	T13523	T13521	neg	not,reach
R3565	T13524	T13525	det	the,value
R3566	T13525	T13521	dobj	value,reach
R3567	T13526	T13527	amod	significant,threshold
R3568	T13527	T13525	compound	threshold,value
R3569	T13528	T13525	acl	suggested,value
R3570	T13529	T13528	agent	by,suggested
R3571	T13530	T13529	pobj	Lander,by
R3572	T13531	T13530	cc	and,Lander
R3573	T13532	T13530	conj	Botstein,Lander
R3574	T13533	T13534	punct	[,26
R3575	T13534	T13528	parataxis	26,suggested
R3576	T13535	T13534	punct	],26
R3577	T13536	T13521	punct	.,reach
R3578	T13538	T13539	mark	Although,significant
R3579	T13539	T13541	advcl	significant,is
R3580	T13540	T13539	neg	not,significant
R3581	T13542	T13541	punct	", ",is
R3582	T13543	T13541	expl	there,is
R3583	T13544	T13541	attr	evidence,is
R3584	T13545	T13546	mark	that,contain
R3585	T13546	T13544	acl	contain,evidence
R3586	T13547	T13546	nsubj	most,contain
R3587	T13548	T13547	prep	of,most
R3588	T13549	T13550	det	the,QTL
R3589	T13550	T13548	pobj	QTL,of
R3590	T13551	T13550	nummod	eight,QTL
R3591	T13552	T13553	amod	small,effect
R3592	T13553	T13550	compound	effect,QTL
R3593	T13554	T13553	punct	-,effect
R3594	T13555	T13546	advmod	likely,contain
R3595	T13556	T13557	compound	susceptibility,genes
R3596	T13557	T13546	dobj	genes,contain
R3597	T13558	T13557	prep	for,genes
R3598	T13559	T13558	pobj	CIA,for
R3599	T13560	T13541	punct	.,is
R3600	T13562	T13563	advmod	First,performed
R3601	T13564	T13563	punct	", ",performed
R3602	T13565	T13563	nsubj	we,performed
R3603	T13566	T13567	det	the,analysis
R3604	T13567	T13563	dobj	analysis,performed
R3605	T13568	T13567	compound	linkage,analysis
R3606	T13569	T13563	prep	in,performed
R3607	T13570	T13571	nummod	three,datasets
R3608	T13571	T13569	pobj	datasets,in
R3609	T13572	T13571	punct	", ",datasets
R3610	T13573	T13571	prep	including,datasets
R3611	T13574	T13575	det	all,progeny
R3612	T13575	T13573	pobj	progeny,including
R3613	T13576	T13575	nummod	290,progeny
R3614	T13577	T13575	compound	F,progeny
R3615	T13578	T13575	punct	", ",progeny
R3616	T13579	T13580	nummod	76,progeny
R3617	T13580	T13575	conj	progeny,progeny
R3618	T13581	T13580	nmod	C5+,progeny
R3619	T13582	T13581	punct	/,C5+
R3620	T13583	T13581	punct	+,C5+
R3621	T13584	T13580	compound	F2,progeny
R3622	T13585	T13580	cc	and,progeny
R3623	T13586	T13587	nummod	133,progeny
R3624	T13587	T13580	conj	progeny,progeny
R3625	T13588	T13587	nmod	C5+,progeny
R3626	T13589	T13588	punct	/,C5+
R3627	T13590	T13588	punct	-,C5+
R3628	T13591	T13587	compound	F2,progeny
R3629	T13592	T13563	punct	.,performed
R3630	T13594	T13595	quantmod	Five,eight
R3631	T13595	T13598	nummod	eight,QTL
R3632	T13596	T13595	quantmod	of,eight
R3633	T13597	T13595	quantmod	the,eight
R3634	T13598	T13602	nsubjpass	QTL,identified
R3635	T13599	T13600	amod	small,effect
R3636	T13600	T13598	compound	effect,QTL
R3637	T13601	T13600	punct	-,effect
R3638	T13603	T13602	auxpass	were,identified
R3639	T13604	T13602	prep	in,identified
R3640	T13605	T13606	advmod	at,two
R3641	T13606	T13608	nummod	two,datasets
R3642	T13607	T13606	advmod	least,two
R3643	T13608	T13604	pobj	datasets,in
R3644	T13609	T13602	punct	", ",identified
R3645	T13610	T13602	advcl	suggesting,identified
R3646	T13611	T13612	mark	that,are
R3647	T13612	T13610	ccomp	are,suggesting
R3648	T13613	T13614	det	these,QTL
R3649	T13614	T13612	nsubj	QTL,are
R3650	T13615	T13612	acomp	reproducible,are
R3651	T13616	T13602	punct	.,identified
R3652	T13618	T13619	advmod	Second,overlap
R3653	T13620	T13619	punct	", ",overlap
R3654	T13621	T13622	amod	many,QTL
R3655	T13622	T13619	nsubj	QTL,overlap
R3656	T13623	T13622	acl	identified,QTL
R3657	T13624	T13623	prep	in,identified
R3658	T13625	T13626	det	the,study
R3659	T13626	T13624	pobj	study,in
R3660	T13627	T13626	amod	present,study
R3661	T13628	T13619	prep	with,overlap
R3662	T13629	T13630	compound	arthritis,QTL
R3663	T13630	T13628	pobj	QTL,with
R3664	T13631	T13632	advmod	previously,identified
R3665	T13632	T13630	acl	identified,QTL
R3666	T13633	T13630	punct	", ",QTL
R3667	T13634	T13630	prep	including,QTL
R3668	T13635	T13636	nmod	loci,1
R3669	T13636	T13634	pobj	1,including
R3670	T13637	T13636	punct	", ",1
R3671	T13638	T13636	conj	2,1
R3672	T13639	T13638	punct	", ",2
R3673	T13640	T13638	conj	5,2
R3674	T13641	T13640	cc	and,5
R3675	T13642	T13640	conj	6,5
R3676	T13643	T13619	punct	.,overlap
R3677	T13645	T13646	prep	In,revealed
R3678	T13647	T13645	pobj	addition,In
R3679	T13648	T13646	punct	", ",revealed
R3680	T13649	T13650	amod	syntenic,analysis
R3681	T13650	T13646	nsubj	analysis,revealed
R3682	T13651	T13652	mark	that,linked
R3683	T13652	T13646	ccomp	linked,revealed
R3684	T13653	T13654	det	the,regions
R3685	T13654	T13652	nsubjpass	regions,linked
R3686	T13655	T13654	nmod	counterpart,regions
R3687	T13656	T13654	amod	genomic,regions
R3688	T13657	T13654	prep	on,regions
R3689	T13658	T13659	det	the,genome
R3690	T13659	T13657	pobj	genome,on
R3691	T13660	T13659	amod	human,genome
R3692	T13661	T13659	prep	of,genome
R3693	T13662	T13661	pobj	many,of
R3694	T13663	T13662	prep	of,many
R3695	T13664	T13665	det	these,QTL
R3696	T13665	T13663	pobj	QTL,of
R3697	T13666	T13665	nummod	eight,QTL
R3698	T13667	T13652	auxpass	are,linked
R3699	T13668	T13652	prep	to,linked
R3700	T13669	T13668	pobj	RA,to
R3701	T13670	T13646	punct	.,revealed
R3702	T13672	T13673	prep	For,are
R3703	T13674	T13675	quantmod	five,eight
R3704	T13675	T13678	nummod	eight,QTL
R3705	T13676	T13675	quantmod	of,eight
R3706	T13677	T13675	quantmod	the,eight
R3707	T13678	T13672	pobj	QTL,For
R3708	T13679	T13680	amod	small,effect
R3709	T13680	T13678	compound	effect,QTL
R3710	T13681	T13680	punct	-,effect
R3711	T13682	T13683	det	the,alleles
R3712	T13683	T13673	nsubj	alleles,are
R3713	T13684	T13683	nmod	DBA,alleles
R3714	T13685	T13684	punct	/,DBA
R3715	T13686	T13684	nummod	1,DBA
R3716	T13687	T13688	det	the,alleles
R3717	T13688	T13673	attr	alleles,are
R3718	T13689	T13690	npadvmod	arthritis,enhancing
R3719	T13690	T13688	amod	enhancing,alleles
R3720	T13691	T13690	punct	-,enhancing
R3721	T13692	T13673	punct	", ",are
R3722	T13693	T13694	mark	while,are
R3723	T13694	T13673	advcl	are,are
R3724	T13695	T13696	det	the,alleles
R3725	T13696	T13694	nsubj	alleles,are
R3726	T13697	T13696	compound	FVBN,alleles
R3727	T13698	T13699	det	the,alleles
R3728	T13699	T13694	attr	alleles,are
R3729	T13700	T13701	npadvmod	arthritis,enhancing
R3730	T13701	T13699	amod	enhancing,alleles
R3731	T13702	T13701	punct	-,enhancing
R3732	T13703	T13694	prep	in,are
R3733	T13704	T13705	det	the,QTL
R3734	T13705	T13703	pobj	QTL,in
R3735	T13706	T13705	amod	other,QTL
R3736	T13707	T13705	nummod	three,QTL
R3737	T13708	T13694	punct	", ",are
R3738	T13709	T13694	advcl	indicating,are
R3739	T13710	T13711	mark	that,come
R3740	T13711	T13709	ccomp	come,indicating
R3741	T13712	T13713	det	some,genes
R3742	T13713	T13711	nsubj	genes,come
R3743	T13714	T13713	compound	susceptibility,genes
R3744	T13715	T13711	aux	could,come
R3745	T13716	T13711	prep	from,come
R3746	T13717	T13718	det	the,strain
R3747	T13718	T13716	pobj	strain,from
R3748	T13719	T13718	amod	resistant,strain
R3749	T13720	T13673	punct	.,are
R3750	T13722	T13723	advmod	Interestingly,overlap
R3751	T13724	T13723	punct	", ",overlap
R3752	T13725	T13726	nmod	loci,2
R3753	T13726	T13723	nsubj	2,overlap
R3754	T13727	T13726	cc	and,2
R3755	T13728	T13726	conj	7,2
R3756	T13729	T13723	advmod	partially,overlap
R3757	T13730	T13723	prep	with,overlap
R3758	T13731	T13732	nummod	two,QTL
R3759	T13732	T13730	pobj	QTL,with
R3760	T13733	T13734	npadvmod	arthritis,related
R3761	T13734	T13732	amod	related,QTL
R3762	T13735	T13734	punct	-,related
R3763	T13736	T13732	acl	identified,QTL
R3764	T13737	T13736	agent	by,identified
R3765	T13738	T13737	pobj	us,by
R3766	T13739	T13736	prep	in,identified
R3767	T13740	T13741	det	the,progeny
R3768	T13741	T13739	pobj	progeny,in
R3769	T13742	T13741	amod	same,progeny
R3770	T13743	T13741	compound	F2,progeny
R3771	T13744	T13745	punct	[,10
R3772	T13745	T13723	parataxis	10,overlap
R3773	T13746	T13745	punct	],10
R3774	T13747	T13723	punct	.,overlap
R3775	T13749	T13750	nsubjpass	Locus,located
R3776	T13751	T13749	nummod	2,Locus
R3777	T13752	T13750	auxpass	was,located
R3778	T13753	T13750	prep	at,located
R3779	T13754	T13755	det	the,region
R3780	T13755	T13753	pobj	region,at
R3781	T13756	T13755	amod	same,region
R3782	T13757	T13755	amod	genomic,region
R3783	T13758	T13755	prep	as,region
R3784	T13759	T13758	pobj	Cia27,as
R3785	T13760	T13759	punct	", ",Cia27
R3786	T13761	T13762	det	a,QTL
R3787	T13762	T13759	appos	QTL,Cia27
R3788	T13763	T13762	acl	controlling,QTL
R3789	T13764	T13765	compound	IgG2a,levels
R3790	T13765	T13763	dobj	levels,controlling
R3791	T13766	T13765	compound	antibody,levels
R3792	T13767	T13765	prep	to,levels
R3793	T13768	T13767	pobj	collagen,to
R3794	T13769	T13768	nummod	II,collagen
R3795	T13770	T13750	punct	.,located
R3796	T13772	T13773	advmod	Recently,refined
R3797	T13774	T13773	punct	", ",refined
R3798	T13775	T13773	nsubj	we,refined
R3799	T13776	T13773	aux	have,refined
R3800	T13777	T13778	det	this,QTL
R3801	T13778	T13773	dobj	QTL,refined
R3802	T13779	T13773	prep	into,refined
R3803	T13780	T13781	det	a,region
R3804	T13781	T13779	pobj	region,into
R3805	T13782	T13783	nummod	4.1,Mb
R3806	T13783	T13781	nmod	Mb,region
R3807	T13784	T13781	amod	genomic,region
R3808	T13785	T13773	cc	and,refined
R3809	T13786	T13773	conj	showed,refined
R3810	T13787	T13788	mark	that,regulates
R3811	T13788	T13786	ccomp	regulates,showed
R3812	T13789	T13790	det	a,gene
R3813	T13790	T13788	nsubj	gene,regulates
R3814	T13791	T13790	prep	within,gene
R3815	T13792	T13793	det	this,region
R3816	T13793	T13791	pobj	region,within
R3817	T13794	T13795	compound	CIA,severity
R3818	T13795	T13788	dobj	severity,regulates
R3819	T13796	T13788	prep	by,regulates
R3820	T13797	T13796	pcomp	controlling,by
R3821	T13798	T13799	det	the,levels
R3822	T13799	T13797	dobj	levels,controlling
R3823	T13800	T13799	compound	IgG2a,levels
R3824	T13801	T13799	compound	antibody,levels
R3825	T13802	T13799	prep	to,levels
R3826	T13803	T13802	pobj	collagen,to
R3827	T13804	T13803	nummod	II,collagen
R3828	T13805	T13806	punct	[,31
R3829	T13806	T13786	parataxis	31,showed
R3830	T13807	T13806	punct	],31
R3831	T13808	T13773	punct	.,refined
R3832	T13810	T13811	nsubj	Locus,overlaps
R3833	T13812	T13810	nummod	7,Locus
R3834	T13813	T13810	prep	on,Locus
R3835	T13814	T13813	pobj	chromosome,on
R3836	T13815	T13814	nummod	16,chromosome
R3837	T13816	T13811	prep	with,overlaps
R3838	T13817	T13816	pobj	Lp1,with
R3839	T13818	T13817	punct	", ",Lp1
R3840	T13819	T13820	dep	which,controls
R3841	T13820	T13817	relcl	controls,Lp1
R3842	T13821	T13822	compound	lymphocyte,proliferation
R3843	T13822	T13820	dobj	proliferation,controls
R3844	T13823	T13811	punct	.,overlaps
R3845	T13825	T13826	advmod	Furthermore,controls
R3846	T13827	T13826	punct	", ",controls
R3847	T13828	T13826	prep	according,controls
R3848	T13829	T13828	prep	to,according
R3849	T13830	T13831	poss	our,data
R3850	T13831	T13829	pobj	data,to
R3851	T13832	T13831	amod	unpublished,data
R3852	T13833	T13826	punct	", ",controls
R3853	T13834	T13826	nsubj	loci,controls
R3854	T13835	T13834	nummod	8,loci
R3855	T13836	T13834	prep	on,loci
R3856	T13837	T13836	pobj	chromosome,on
R3857	T13838	T13837	nummod	17,chromosome
R3858	T13839	T13840	compound	lymphocyte,adherence
R3859	T13840	T13826	dobj	adherence,controls
R3860	T13841	T13826	prep	during,controls
R3861	T13842	T13841	pobj	development,during
R3862	T13843	T13842	prep	of,development
R3863	T13844	T13843	pobj	CIA,of
R3864	T13845	T13826	punct	.,controls
R3865	T13847	T13848	advmod	Therefore,affect
R3866	T13849	T13848	punct	", ",affect
R3867	T13850	T13851	det	the,gene
R3868	T13851	T13848	nsubj	gene,affect
R3869	T13852	T13851	prep	within,gene
R3870	T13853	T13854	det	the,QTL
R3871	T13854	T13852	pobj	QTL,within
R3872	T13855	T13856	amod	small,effect
R3873	T13856	T13854	compound	effect,QTL
R3874	T13857	T13856	punct	-,effect
R3875	T13858	T13848	aux	could,affect
R3876	T13859	T13860	compound	CIA,severity
R3877	T13860	T13848	dobj	severity,affect
R3878	T13861	T13848	prep	through,affect
R3879	T13862	T13861	pcomp	controlling,through
R3880	T13863	T13864	npadvmod	arthritis,related
R3881	T13864	T13866	amod	related,phenotypes
R3882	T13865	T13864	punct	-,related
R3883	T13866	T13862	dobj	phenotypes,controlling
R3884	T13867	T13848	punct	.,affect
R3885	T13869	T13870	amod	Several,studies
R3886	T13870	T13871	nsubjpass	studies,carried
R3887	T13872	T13871	aux	have,carried
R3888	T13873	T13871	auxpass	been,carried
R3889	T13874	T13871	prt	out,carried
R3890	T13875	T13876	aux	to,detect
R3891	T13876	T13871	advcl	detect,carried
R3892	T13877	T13878	compound	gene,expression
R3893	T13878	T13876	dobj	expression,detect
R3894	T13879	T13876	prep	during,detect
R3895	T13880	T13879	pobj	CIA,during
R3896	T13881	T13871	punct	", ",carried
R3897	T13882	T13883	dep	all,used
R3898	T13883	T13871	ccomp	used,carried
R3899	T13884	T13882	prep	of,all
R3900	T13885	T13884	pobj	which,of
R3901	T13886	T13883	dobj	joints,used
R3902	T13887	T13883	prep	as,used
R3903	T13888	T13889	det	the,tissue
R3904	T13889	T13887	pobj	tissue,as
R3905	T13890	T13889	compound	target,tissue
R3906	T13891	T13892	punct	[,22
R3907	T13892	T13871	parataxis	22,carried
R3908	T13893	T13892	nummod	15,22
R3909	T13894	T13892	punct	",",22
R3910	T13895	T13892	nummod	16,22
R3911	T13896	T13892	punct	",",22
R3912	T13897	T13892	nummod	21,22
R3913	T13898	T13892	punct	",",22
R3914	T13899	T13892	punct	],22
R3915	T13900	T13871	punct	.,carried
R3916	T13902	T13903	det	This,study
R3917	T13903	T13904	nsubj	study,detected
R3918	T13905	T13904	punct	", ",detected
R3919	T13906	T13904	prep	for,detected
R3920	T13907	T13908	det	the,time
R3921	T13908	T13906	pobj	time,for
R3922	T13909	T13908	amod	first,time
R3923	T13910	T13904	punct	", ",detected
R3924	T13911	T13912	compound	gene,expression
R3925	T13912	T13904	dobj	expression,detected
R3926	T13913	T13904	prep	in,detected
R3927	T13914	T13913	pobj	LNs,in
R3928	T13915	T13904	prep	during,detected
R3929	T13916	T13915	pobj	CIA,during
R3930	T13917	T13904	punct	.,detected
R3931	T13919	T13920	nsubj	We,present
R3932	T13921	T13922	det	an,study
R3933	T13922	T13920	dobj	study,present
R3934	T13923	T13922	amod	extensive,study
R3935	T13924	T13922	prep	of,study
R3936	T13925	T13926	compound	gene,patterns
R3937	T13926	T13924	pobj	patterns,of
R3938	T13927	T13926	compound	expression,patterns
R3939	T13928	T13922	prep	in,study
R3940	T13929	T13928	pobj	LNs,in
R3941	T13930	T13929	prep	of,LNs
R3942	T13931	T13932	preconj	both,strains
R3943	T13932	T13930	pobj	strains,of
R3944	T13933	T13934	advmod	genetically,susceptible
R3945	T13934	T13932	amod	susceptible,strains
R3946	T13935	T13934	cc	and,susceptible
R3947	T13936	T13934	conj	resistant,susceptible
R3948	T13937	T13922	prep	at,study
R3949	T13938	T13939	nummod	four,phases
R3950	T13939	T13937	pobj	phases,at
R3951	T13940	T13939	amod	different,phases
R3952	T13941	T13939	prep	of,phases
R3953	T13942	T13941	pobj	CIA,of
R3954	T13943	T13920	punct	.,present
R3955	T13945	T13946	prep	In,were
R3956	T13947	T13948	det	both,strains
R3957	T13948	T13945	pobj	strains,In
R3958	T13949	T13946	punct	", ",were
R3959	T13950	T13951	advmod	differentially,regulated
R3960	T13951	T13952	amod	regulated,genes
R3961	T13952	T13946	nsubj	genes,were
R3962	T13953	T13954	advmod	highly,concentrated
R3963	T13954	T13946	acomp	concentrated,were
R3964	T13955	T13946	prep	at,were
R3965	T13956	T13957	det	the,phases
R3966	T13957	T13955	pobj	phases,at
R3967	T13958	T13957	nmod	PI,phases
R3968	T13959	T13958	cc	and,PI
R3969	T13960	T13958	conj	CA,PI
R3970	T13961	T13946	punct	", ",were
R3971	T13962	T13946	cc	and,were
R3972	T13963	T13964	advmod	only,number
R3973	T13964	T13967	nsubjpass	number,expressed
R3974	T13965	T13964	det	a,number
R3975	T13966	T13964	amod	small,number
R3976	T13967	T13946	conj	expressed,were
R3977	T13968	T13964	prep	of,number
R3978	T13969	T13968	pobj	genes,of
R3979	T13970	T13967	auxpass	were,expressed
R3980	T13971	T13967	advmod	differentially,expressed
R3981	T13972	T13967	prep	in,expressed
R3982	T13973	T13974	nummod	two,phases
R3983	T13974	T13972	pobj	phases,in
R3984	T13975	T13973	cc	or,two
R3985	T13976	T13973	conj	three,two
R3986	T13977	T13967	punct	.,expressed
R3987	T13979	T13980	nsubj	This,indicates
R3988	T13981	T13982	mark	that,were
R3989	T13982	T13980	ccomp	were,indicates
R3990	T13983	T13984	amod	biological,responses
R3991	T13984	T13982	nsubj	responses,were
R3992	T13985	T13984	prep	in,responses
R3993	T13986	T13985	pobj	LNs,in
R3994	T13987	T13982	acomp	stronger,were
R3995	T13988	T13987	prep	in,stronger
R3996	T13989	T13990	det	the,phases
R3997	T13990	T13988	pobj	phases,in
R3998	T13991	T13990	nmod	PI,phases
R3999	T13992	T13991	cc	and,PI
R4000	T13993	T13991	conj	CA,PI
R4001	T13994	T13987	prep	than,stronger
R4002	T13995	T13994	prep	in,than
R4003	T13996	T13997	det	the,phase
R4004	T13997	T13995	pobj	phase,in
R4005	T13998	T13997	compound	OA,phase
R4006	T13999	T13982	punct	", ",were
R4007	T14000	T13982	cc	and,were
R4008	T14001	T14002	det	the,responses
R4009	T14002	T14003	nsubj	responses,were
R4010	T14003	T13982	conj	were,were
R4011	T14004	T14002	prep	at,responses
R4012	T14005	T14006	amod	different,phases
R4013	T14006	T14004	pobj	phases,at
R4014	T14007	T14003	acomp	different,were
R4015	T14008	T13980	punct	.,indicates
R4016	T14010	T14011	advmod	When,comparing
R4017	T14011	T14012	advcl	comparing,found
R4018	T14013	T14014	det	the,susceptible
R4019	T14014	T14011	dative	susceptible,comparing
R4020	T14015	T14011	prep	to,comparing
R4021	T14016	T14017	det	the,resistant
R4022	T14017	T14015	pobj	resistant,to
R4023	T14018	T14011	dobj	strain,comparing
R4024	T14019	T14012	punct	", ",found
R4025	T14020	T14021	det	the,difference
R4026	T14021	T14012	nsubjpass	difference,found
R4027	T14022	T14021	amod	biggest,difference
R4028	T14023	T14012	auxpass	was,found
R4029	T14024	T14012	prep	in,found
R4030	T14025	T14026	nummod	one,cluster
R4031	T14026	T14024	pobj	cluster,in
R4032	T14027	T14026	prep	of,cluster
R4033	T14028	T14027	pobj	genes,of
R4034	T14029	T14026	punct	(,cluster
R4035	T14030	T14026	appos	cluster,cluster
R4036	T14031	T14030	nummod	IV,cluster
R4037	T14032	T14033	punct	", ",Figure
R4038	T14033	T14012	parataxis	Figure,found
R4039	T14034	T14033	nummod	2,Figure
R4040	T14035	T14033	punct	),Figure
R4041	T14036	T14012	punct	.,found
R4042	T14038	T14039	det	These,genes
R4043	T14039	T14040	nsubj	genes,had
R4044	T14041	T14042	det	a,expression
R4045	T14042	T14040	dobj	expression,had
R4046	T14043	T14042	amod	higher,expression
R4047	T14044	T14042	prep	in,expression
R4048	T14045	T14044	pobj	DBA,in
R4049	T14046	T14045	punct	/,DBA
R4050	T14047	T14045	nummod	1,DBA
R4051	T14048	T14042	prep	than,expression
R4052	T14049	T14048	prep	in,than
R4053	T14050	T14051	compound	FVB,N
R4054	T14051	T14049	pobj	N,in
R4055	T14052	T14051	punct	/,N
R4056	T14053	T14040	prep	at,had
R4057	T14054	T14055	det	the,phases
R4058	T14055	T14053	pobj	phases,at
R4059	T14056	T14055	amod	early,phases
R4060	T14057	T14055	prep	of,phases
R4061	T14058	T14057	pobj	CIA,of
R4062	T14059	T14060	punct	(,NC
R4063	T14060	T14055	parataxis	NC,phases
R4064	T14061	T14060	punct	", ",NC
R4065	T14062	T14060	conj	PI,NC
R4066	T14063	T14062	cc	and,PI
R4067	T14064	T14062	conj	OA,PI
R4068	T14065	T14060	punct	),NC
R4069	T14066	T14040	cc	and,had
R4070	T14067	T14068	det	the,pattern
R4071	T14068	T14040	conj	pattern,had
R4072	T14069	T14068	amod	opposite,pattern
R4073	T14070	T14068	compound	expression,pattern
R4074	T14071	T14068	prep	in,pattern
R4075	T14072	T14073	det	the,phase
R4076	T14073	T14071	pobj	phase,in
R4077	T14074	T14073	compound	CA,phase
R4078	T14075	T14040	punct	.,had
R4079	T14077	T14078	compound	GO,classification
R4080	T14078	T14080	nsubj	classification,revealed
R4081	T14079	T14078	compound	term,classification
R4082	T14081	T14082	mark	that,related
R4083	T14082	T14080	ccomp	related,revealed
R4084	T14083	T14084	det	these,genes
R4085	T14084	T14082	nsubjpass	genes,related
R4086	T14085	T14082	auxpass	were,related
R4087	T14086	T14082	prep	to,related
R4088	T14087	T14088	compound	lymphocyte,proliferation
R4089	T14088	T14086	pobj	proliferation,to
R4090	T14089	T14088	cc	and,proliferation
R4091	T14090	T14088	conj	activation,proliferation
R4092	T14091	T14082	punct	", ",related
R4093	T14092	T14082	advcl	suggesting,related
R4094	T14093	T14094	mark	that,are
R4095	T14094	T14092	ccomp	are,suggesting
R4096	T14095	T14094	nsubj	lymphocytes,are
R4097	T14096	T14095	prep	in,lymphocytes
R4098	T14097	T14098	det	the,strain
R4099	T14098	T14096	pobj	strain,in
R4100	T14099	T14098	nmod	DBA,strain
R4101	T14100	T14099	punct	/,DBA
R4102	T14123	T14115	advcl	existed,is
R4103	T14101	T14099	nummod	1,DBA
R4104	T14124	T14125	det	the,difference
R4105	T14102	T14103	advmod	more,activated
R4106	T14125	T14123	nsubj	difference,existed
R4107	T14126	T14125	compound	expression,difference
R4109	T14103	T14094	acomp	activated,are
R4110	T14128	T14129	det	the,strains
R4112	T14104	T14103	prep	than,activated
R4113	T14130	T14129	nummod	two,strains
R4114	T14131	T14123	prep	in,existed
R4115	T14132	T14131	pobj	mice,in
R4116	T14105	T14104	pobj	those,than
R4117	T14133	T14132	prep	without,mice
R4118	T14134	T14133	pobj	immunisation,without
R4119	T14135	T14115	punct	.,is
R4120	T14106	T14105	prep	in,those
R4121	T14137	T14138	advmod	Additionally,upregulated
R4122	T14107	T14108	det	the,strain
R4123	T14139	T14138	punct	", ",upregulated
R4124	T14108	T14106	pobj	strain,in
R4125	T14140	T14141	det	some,genes
R4126	T14141	T14138	nsubjpass	genes,upregulated
R4127	T14142	T14141	acl	related,genes
R4128	T14109	T14110	compound	FVB,N
R4129	T14143	T14142	prep	to,related
R4130	T14144	T14145	det	the,response
R4131	T14110	T14108	compound	N,strain
R4132	T14145	T14143	pobj	response,to
R4133	T14146	T14145	amod	immune,response
R4134	T14147	T14138	auxpass	were,upregulated
R4135	T14148	T14138	prep	in,upregulated
R4136	T14149	T14150	det	the,strain
R4137	T14150	T14148	pobj	strain,in
R4138	T14111	T14110	punct	/,N
R4139	T14151	T14150	nmod	DBA,strain
R4140	T14152	T14151	punct	/,DBA
R4141	T14153	T14151	nummod	1,DBA
R4142	T14112	T14080	punct	.,revealed
R4143	T14154	T14148	cc	but,in
R4144	T14155	T14154	neg	not,but
R4145	T14156	T14148	conj	in,in
R4146	T14157	T14158	det	the,strain
R4147	T14114	T14115	advmod	However,is
R4148	T14158	T14156	pobj	strain,in
R4149	T14159	T14160	compound	FVB,N
R4150	T14160	T14158	compound	N,strain
R4151	T14161	T14160	punct	/,N
R4152	T14116	T14115	punct	", ",is
R4153	T14162	T14138	prep	during,upregulated
R4154	T14163	T14162	pobj	CIA,during
R4155	T14164	T14138	punct	.,upregulated
R4156	T14166	T14167	det	These,differences
R4157	T14117	T14118	det	this,difference
R4158	T14167	T14168	nsubj	differences,explain
R4159	T14169	T14168	aux	could,explain
R4160	T14118	T14115	nsubj	difference,is
R4161	T14170	T14171	advmod	why,occurred
R4162	T14119	T14115	neg	not,is
R4163	T14120	T14121	npadvmod	CIA,specific
R4164	T14171	T14168	ccomp	occurred,explain
R4165	T14172	T14173	det	a,response
R4166	T14121	T14115	acomp	specific,is
R4167	T14173	T14171	nsubj	response,occurred
R4168	T14174	T14173	amod	higher,response
R4169	T14175	T14173	compound	antibody,response
R4170	T14122	T14123	mark	because,existed
R4171	T14176	T14173	prep	to,response
R4172	T14177	T14176	pobj	collagen,to
R4173	T14178	T14177	nummod	II,collagen
R4174	T14179	T14171	prep	in,occurred
R4175	T14229	T14228	prep	to,according
R4176	T14180	T14181	det	the,strain
R4177	T14181	T14179	pobj	strain,in
R4178	T14182	T14181	nmod	DBA,strain
R4179	T14183	T14182	punct	/,DBA
R4180	T14230	T14231	poss	their,patterns
R4181	T14184	T14182	nummod	1,DBA
R4182	T14185	T14171	prep	compared,occurred
R4183	T14231	T14229	pobj	patterns,to
R4184	T14186	T14185	prep	to,compared
R4185	T14187	T14188	det	the,strain
R4186	T14188	T14186	pobj	strain,to
R4187	T14189	T14190	compound	FVB,N
R4188	T14190	T14188	compound	N,strain
R4189	T14232	T14233	compound	gene,expression
R4190	T14191	T14190	punct	/,N
R4191	T14192	T14168	punct	", ",explain
R4192	T14193	T14168	cc	and,explain
R4193	T14194	T14195	aux	might,explain
R4194	T14233	T14231	compound	expression,patterns
R4195	T14195	T14168	conj	explain,explain
R4196	T14234	T14213	prep	during,identified
R4197	T14196	T14195	advmod	partially,explain
R4198	T14197	T14198	det	the,difference
R4199	T14198	T14195	dobj	difference,explain
R4200	T14199	T14198	prep	of,difference
R4201	T14235	T14234	pobj	CIA,during
R4202	T14200	T14201	det	the,susceptibility
R4203	T14201	T14199	pobj	susceptibility,of
R4204	T14202	T14201	prep	to,susceptibility
R4205	T14203	T14202	pobj	CIA,to
R4206	T14236	T14235	cc	and,CIA
R4207	T14204	T14198	prep	between,difference
R4208	T14205	T14206	det	both,strains
R4209	T14206	T14204	pobj	strains,between
R4210	T14237	T14238	poss	their,locations
R4211	T14207	T14168	punct	.,explain
R4212	T14209	T14210	compound	Twenty,one
R4213	T14238	T14235	conj	locations,CIA
R4214	T14210	T14212	nummod	one,genes
R4215	T14211	T14210	punct	-,one
R4216	T14212	T14213	nsubjpass	genes,identified
R4217	T14239	T14238	amod	genomic,locations
R4218	T14214	T14213	auxpass	were,identified
R4219	T14215	T14213	prep	as,identified
R4220	T14216	T14217	amod	potential,genes
R4221	T14240	T14213	punct	.,identified
R4222	T14217	T14215	pobj	genes,as
R4223	T14218	T14217	compound	candidate,genes
R4224	T14219	T14213	prep	for,identified
R4225	T14242	T14243	det	No,genes
R4226	T14220	T14221	quantmod	six,eight
R4227	T14221	T14224	nummod	eight,QTL
R4228	T14222	T14221	quantmod	of,eight
R4229	T14223	T14221	quantmod	the,eight
R4230	T14243	T14245	nsubjpass	genes,located
R4231	T14224	T14219	pobj	QTL,for
R4232	T14225	T14226	amod	small,effect
R4233	T14226	T14224	compound	effect,QTL
R4234	T14244	T14243	compound	candidate,genes
R4235	T14227	T14226	punct	-,effect
R4236	T14228	T14213	prep	according,identified
R4237	T14246	T14245	auxpass	were,located
R4238	T14247	T14245	prep	in,located
R4239	T14248	T14249	nmod	QTL,4
R4240	T14336	T14337	advmod	Moreover,attenuate
R4241	T14249	T14247	pobj	4,in
R4242	T14338	T14337	punct	", ",attenuate
R4243	T14339	T14337	nsubj	inhibitors,attenuate
R4244	T14340	T14339	prep	of,inhibitors
R4245	T14341	T14342	compound	p38,MAPK
R4246	T14250	T14249	cc	and,4
R4247	T14342	T14340	pobj	MAPK,of
R4248	T14343	T14337	aux	could,attenuate
R4249	T14344	T14337	dobj	CIA,attenuate
R4250	T14251	T14249	conj	7,4
R4251	T14345	T14337	prep	in,attenuate
R4252	T14252	T14245	punct	", ",located
R4253	T14346	T14345	pobj	rats,in
R4254	T14347	T14348	punct	[,33
R4255	T14348	T14337	parataxis	33,attenuate
R4256	T14349	T14348	punct	],33
R4257	T14253	T14245	advcl	suggesting,located
R4258	T14254	T14255	mark	that,affect
R4259	T14350	T14337	punct	", ",attenuate
R4260	T14351	T14337	cc	and,attenuate
R4261	T14352	T14353	compound	p38,MAPK
R4262	T14255	T14253	ccomp	affect,suggesting
R4263	T14353	T14354	nsubj	MAPK,becoming
R4264	T14354	T14337	conj	becoming,attenuate
R4265	T14355	T14354	aux	is,becoming
R4266	T14356	T14357	det	a,target
R4267	T14256	T14257	compound	QTG,polymorphisms
R4268	T14357	T14354	attr	target,becoming
R4269	T14358	T14357	amod	potential,target
R4270	T14359	T14357	amod	therapeutic,target
R4271	T14257	T14255	nsubj	polymorphisms,affect
R4272	T14360	T14354	prep	in,becoming
R4273	T14361	T14360	pobj	RA,in
R4274	T14362	T14363	punct	[,32
R4275	T14363	T14354	parataxis	32,becoming
R4276	T14258	T14257	prep	of,polymorphisms
R4277	T14364	T14363	punct	],32
R4278	T14365	T14337	punct	.,attenuate
R4279	T14367	T14368	nsubj	Stat5a,is
R4280	T14259	T14260	det	the,genes
R4281	T14369	T14367	punct	", ",Stat5a
R4282	T14370	T14371	det	a,gene
R4283	T14260	T14258	pobj	genes,of
R4284	T14371	T14367	appos	gene,Stat5a
R4285	T14372	T14371	compound	candidate,gene
R4286	T14373	T14371	prep	for,gene
R4287	T14374	T14373	pobj	loci,for
R4288	T14261	T14260	compound	susceptibility,genes
R4289	T14375	T14374	nummod	6,loci
R4290	T14376	T14368	punct	", ",is
R4291	T14377	T14378	det	an,molecule
R4292	T14378	T14368	attr	molecule,is
R4293	T14379	T14378	amod	essential,molecule
R4294	T14380	T14378	prep	for,molecule
R4295	T14381	T14382	compound	lymphoid,development
R4296	T14262	T14257	prep	inside,polymorphisms
R4297	T14382	T14380	pobj	development,for
R4298	T14383	T14382	cc	and,development
R4299	T14384	T14382	conj	differentiation,development
R4300	T14385	T14386	punct	[,34
R4301	T14263	T14264	det	these,QTL
R4302	T14386	T14368	parataxis	34,is
R4303	T14387	T14386	punct	],34
R4304	T14388	T14368	punct	.,is
R4305	T14264	T14262	pobj	QTL,inside
R4306	T14390	T14391	npadvmod	Stat5a,deficient
R4307	T14391	T14393	amod	deficient,mice
R4308	T14265	T14264	nummod	two,QTL
R4309	T14392	T14391	punct	-,deficient
R4310	T14393	T14394	nsubjpass	mice,reported
R4311	T14266	T14255	aux	might,affect
R4312	T14395	T14394	auxpass	were,reported
R4313	T14396	T14397	aux	to,lose
R4314	T14397	T14394	xcomp	lose,reported
R4315	T14267	T14255	neg	not,affect
R4316	T14398	T14397	dobj	tolerance,lose
R4317	T14399	T14397	punct	", ",lose
R4318	T14400	T14397	advcl	resulting,lose
R4319	T14401	T14400	prep	in,resulting
R4320	T14268	T14269	det	the,phenotype
R4321	T14402	T14403	det	the,development
R4322	T14403	T14401	pobj	development,in
R4323	T14404	T14403	prep	of,development
R4324	T14269	T14255	dobj	phenotype,affect
R4325	T14405	T14406	amod	autoimmune,diseases
R4326	T14406	T14404	pobj	diseases,of
R4327	T14270	T14255	prep	by,affect
R4328	T14407	T14394	punct	.,reported
R4329	T14409	T14410	nsubjpass	Stat5a,suggested
R4330	T14271	T14270	pcomp	regulating,by
R4331	T14411	T14410	auxpass	is,suggested
R4332	T14412	T14413	aux	to,contribute
R4333	T14272	T14273	compound	gene,expression
R4334	T14413	T14410	xcomp	contribute,suggested
R4335	T14414	T14413	prep	to,contribute
R4336	T14415	T14414	pobj	tolerance,to
R4337	T14273	T14271	dobj	expression,regulating
R4338	T14416	T14413	prep	through,contribute
R4339	T14417	T14416	pobj	maintenance,through
R4340	T14418	T14417	prep	of,maintenance
R4341	T14419	T14420	det	the,population
R4342	T14420	T14418	pobj	population,of
R4343	T14421	T14420	nmod	CD4+CD25+,population
R4344	T14422	T14420	amod	regulatory,population
R4345	T14274	T14245	punct	.,located
R4346	T14423	T14424	compound	T,cell
R4347	T14424	T14420	compound	cell,population
R4348	T14425	T14426	punct	[,35
R4349	T14426	T14410	parataxis	35,suggested
R4350	T14276	T14277	quantmod	Two,21
R4351	T14427	T14426	punct	],35
R4352	T14428	T14410	punct	.,suggested
R4353	T14430	T14431	advmod	Therefore,presented
R4354	T14277	T14280	nummod	21,genes
R4355	T14432	T14431	punct	", ",presented
R4356	T14278	T14277	quantmod	of,21
R4357	T14433	T14431	nsubj	we,presented
R4358	T14434	T14431	aux	have,presented
R4359	T14435	T14436	det	a,strategy
R4360	T14436	T14431	dobj	strategy,presented
R4361	T14279	T14277	quantmod	the,21
R4362	T14437	T14438	aux	to,identify
R4363	T14438	T14436	advcl	identify,strategy
R4364	T14280	T14282	nsubjpass	genes,reported
R4365	T14439	T14440	amod	small,effect
R4366	T14281	T14280	compound	candidate,genes
R4367	T14440	T14442	compound	effect,QTL
R4368	T14283	T14282	auxpass	were,reported
R4369	T14284	T14285	aux	to,involved
R4370	T14441	T14440	punct	-,effect
R4371	T14285	T14282	xcomp	involved,reported
R4372	T14442	T14438	dobj	QTL,identify
R4373	T14443	T14438	cc	and,identify
R4374	T14444	T14438	conj	search,identify
R4375	T14286	T14285	auxpass	be,involved
R4376	T14445	T14444	prep	for,search
R4377	T14446	T14447	amod	potential,genes
R4378	T14287	T14285	prep	in,involved
R4379	T14447	T14445	pobj	genes,for
R4380	T14448	T14447	compound	candidate,genes
R4381	T14449	T14444	prep	within,search
R4382	T14450	T14449	pobj	them,within
R4383	T14288	T14287	pobj	arthritis,in
R4384	T14451	T14431	punct	.,presented
R4385	T14289	T14282	punct	.,reported
R4386	T14453	T14454	advmod	However,is
R4387	T14455	T14454	punct	", ",is
R4388	T14291	T14292	nsubj	Mapk14,regulates
R4389	T14456	T14454	nsubj	it,is
R4390	T14457	T14454	acomp	noteworthy,is
R4391	T14458	T14459	mark	that,lead
R4392	T14459	T14454	ccomp	lead,is
R4393	T14460	T14461	det	the,threshold
R4394	T14461	T14459	nsubj	threshold,lead
R4395	T14462	T14461	amod	low,threshold
R4396	T14293	T14291	punct	", ",Mapk14
R4397	T14463	T14461	amod	statistical,threshold
R4398	T14464	T14461	cc	and,threshold
R4399	T14465	T14466	amod	small,number
R4400	T14466	T14461	conj	number,threshold
R4401	T14294	T14295	det	a,gene
R4402	T14467	T14466	prep	of,number
R4403	T14468	T14467	pobj	animals,of
R4404	T14469	T14466	prep	per,number
R4405	T14295	T14291	nmod	gene,Mapk14
R4406	T14470	T14469	pobj	group,per
R4407	T14471	T14459	aux	could,lead
R4408	T14472	T14459	prep	to,lead
R4409	T14296	T14295	nmod	candidate,gene
R4410	T14473	T14474	det	some,results
R4411	T14474	T14472	pobj	results,to
R4412	T14475	T14476	amod	false,positive
R4413	T14297	T14295	prep	for,gene
R4414	T14476	T14474	amod	positive,results
R4415	T14477	T14454	punct	.,is
R4416	T14298	T14297	pobj	locus,for
R4417	T14479	T14480	prep	On,be
R4418	T14481	T14482	det	the,level
R4419	T14299	T14298	nummod	8,locus
R4420	T14482	T14479	pobj	level,On
R4421	T14483	T14482	compound	genome,level
R4422	T14484	T14480	punct	", ",be
R4423	T14300	T14295	cc	and,gene
R4424	T14485	T14480	nsubj	some,be
R4425	T14486	T14485	prep	of,some
R4426	T14487	T14488	det	the,QTL
R4427	T14488	T14486	pobj	QTL,of
R4428	T14301	T14302	advmod	also,called
R4429	T14489	T14488	nummod	eight,QTL
R4430	T14490	T14491	amod	small,effect
R4431	T14491	T14488	compound	effect,QTL
R4432	T14302	T14295	conj	called,gene
R4433	T14492	T14491	punct	-,effect
R4434	T14493	T14488	acl	identified,QTL
R4435	T14494	T14493	advcl	using,identified
R4436	T14495	T14496	det	a,value
R4437	T14303	T14304	nmod	p38,kinase
R4438	T14496	T14494	dobj	value,using
R4439	T14497	T14498	advmod	very,low
R4440	T14498	T14496	amod	low,value
R4441	T14304	T14309	nmod	kinase,alpha
R4442	T14499	T14496	compound	threshold,value
R4443	T14500	T14501	punct	(,0.05
R4444	T14501	T14496	parataxis	0.05,value
R4445	T14502	T14501	nsubj	P,0.05
R4446	T14503	T14501	punct	<,0.05
R4447	T14504	T14501	punct	),0.05
R4448	T14305	T14306	npadvmod	mitogen,activated
R4449	T14505	T14480	aux	could,be
R4450	T14506	T14507	amod	false,positives
R4451	T14507	T14480	attr	positives,be
R4452	T14306	T14304	amod	activated,kinase
R4453	T14508	T14480	punct	.,be
R4454	T14510	T14511	prep	For,identified
R4455	T14307	T14306	punct	-,activated
R4456	T14512	T14510	pobj	example,For
R4457	T14513	T14511	punct	", ",identified
R4458	T14308	T14304	nmod	protein,kinase
R4459	T14514	T14511	nsubjpass	locus,identified
R4460	T14515	T14514	nummod	4,locus
R4461	T14309	T14302	oprd	alpha,called
R4462	T14310	T14304	punct	(,kinase
R4463	T14516	T14511	auxpass	was,identified
R4464	T14311	T14304	appos	MAPK,kinase
R4465	T14517	T14511	prep	with,identified
R4466	T14518	T14519	det	a,value
R4467	T14519	T14517	pobj	value,with
R4468	T14312	T14309	punct	),alpha
R4469	T14520	T14519	amod	low,value
R4470	T14521	T14519	compound	P,value
R4471	T14522	T14511	cc	and,identified
R4472	T14313	T14292	punct	", ",regulates
R4473	T14523	T14524	aux	does,overlap
R4474	T14524	T14511	conj	overlap,identified
R4475	T14525	T14524	neg	not,overlap
R4476	T14314	T14315	det	the,production
R4477	T14315	T14292	dobj	production,regulates
R4480	T14316	T14315	prep	of,production
R4484	T14317	T14318	npadvmod	arthritis,essential
R4487	T14318	T14320	amod	essential,cytokines
R4490	T14319	T14318	punct	-,essential
R4493	T14539	T14535	punct	", ",result
R4494	T14320	T14316	pobj	cytokines,of
R4495	T14540	T14541	det	the,number
R4496	T14541	T14535	nsubj	number,result
R4497	T14542	T14541	amod	small,number
R4498	T14543	T14541	prep	of,number
R4499	T14544	T14543	pobj	animals,of
R4500	T14545	T14541	prep	per,number
R4501	T14546	T14545	pobj	group,per
R4502	T14321	T14320	punct	", ",cytokines
R4503	T14322	T14323	amod	such,as
R4504	T14323	T14320	prep	as,cytokines
R4505	T14547	T14541	cc	and,number
R4506	T14548	T14549	det	the,threshold
R4507	T14549	T14541	conj	threshold,number
R4508	T14324	T14325	compound	tumour,factor
R4509	T14550	T14549	amod	low,threshold
R4510	T14551	T14549	acl	used,threshold
R4511	T14552	T14553	aux	to,detect
R4512	T14325	T14323	pobj	factor,as
R4513	T14553	T14551	advcl	detect,used
R4514	T14554	T14555	compound	gene,expression
R4515	T14555	T14553	dobj	expression,detect
R4516	T14326	T14325	compound	necrosis,factor
R4517	T14556	T14535	aux	could,result
R4518	T14557	T14535	advmod	also,result
R4519	T14327	T14325	cc	and,factor
R4520	T14558	T14535	prep	in,result
R4521	T14559	T14560	amod	false,positives
R4522	T14560	T14558	pobj	positives,in
R4523	T14561	T14535	prep	in,result
R4524	T14328	T14325	conj	interleukin,factor
R4525	T14562	T14563	det	the,genes
R4526	T14563	T14561	pobj	genes,in
R4527	T14329	T14328	punct	-,interleukin
R4528	T14564	T14565	advmod	differentially,expressed
R4529	T14565	T14563	amod	expressed,genes
R4530	T14566	T14535	punct	.,result
R4531	T14330	T14328	nummod	1,interleukin
R4532	T14568	T14569	advmod	Furthermore,result
R4533	T14331	T14332	punct	[,32
R4534	T14570	T14569	punct	", ",result
R4535	T14571	T14572	det	the,expression
R4536	T14572	T14569	nsubj	expression,result
R4537	T14332	T14292	parataxis	32,regulates
R4538	T14573	T14572	amod	differential,expression
R4539	T14574	T14572	prep	of,expression
R4540	T14575	T14576	det	a,gene
R4541	T14576	T14574	pobj	gene,of
R4542	T14333	T14332	punct	],32
R4543	T14577	T14569	aux	could,result
R4544	T14578	T14579	preconj	not,from
R4545	T14579	T14569	prep	from,result
R4546	T14334	T14292	punct	.,regulates
R4547	T14580	T14578	advmod	only,not
R4548	T14581	T14582	compound	allele,difference
R4549	T14582	T14579	pobj	difference,from
R4550	T14583	T14582	prep	between,difference
R4551	T14584	T14585	nummod	two,strains
R4552	T14585	T14583	pobj	strains,between
R4553	T14586	T14579	punct	", ",from
R4554	T14587	T14579	cc	but,from
R4555	T14588	T14587	advmod	also,but
R4556	T14589	T14579	conj	from,from
R4557	T14590	T14591	amod	other,factors
R4558	T14591	T14589	pobj	factors,from
R4559	T14592	T14569	punct	.,result
R4560	T14594	T14595	advmod	Therefore,confirmed
R4561	T14596	T14595	punct	", ",confirmed
R4562	T14597	T14598	poss	our,findings
R4563	T14598	T14595	nsubjpass	findings,confirmed
R4564	T14599	T14595	aux	should,confirmed
R4565	T14600	T14595	auxpass	be,confirmed
R4566	T14601	T14595	prep	in,confirmed
R4567	T14602	T14603	amod	future,studies
R4568	T14603	T14601	pobj	studies,in
R4569	T14604	T14595	punct	.,confirmed
R4108	T14127	T14125	prep	between,difference
R4111	T14129	T14127	pobj	strains,between
R4482	T14529	T14530	advmod	previously,identified
R4483	T14530	T14528	amod	identified,QTL
R4486	T14532	T14511	punct	.,identified
R4478	T14526	T14524	prep	with,overlap
R4479	T14527	T14528	det	any,QTL
R4481	T14528	T14526	pobj	QTL,with
R4485	T14531	T14528	compound	arthritis,QTL
R4488	T14534	T14535	prep	On,result
R4489	T14536	T14537	det	the,level
R4491	T14537	T14534	pobj	level,On
R4492	T14538	T14537	compound	transcriptome,level

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id	Subject	Object	Predicate	Lexical cue
T13321	83-86	SO_EXT:0000771	denotes	QTL
T13322	118-121	SO_EXT:0000771	denotes	QTL
T13323	358-361	SO_EXT:0000771	denotes	QTL
T13324	392-397	SO_EXT:0000704	denotes	genes
T13325	499-501	PR_EXT:000004904	denotes	C5
T13326	501-502	SO_EXT:normal_or_wild_type_or_present	denotes	+
T13327	503-504	SO_EXT:normal_or_wild_type_or_present	denotes	+
T13328	524-526	PR_EXT:000004904	denotes	C5
T13329	526-527	SO_EXT:normal_or_wild_type_or_present	denotes	+
T13330	528-529	SO_EXT:sequence_nullness_or_absence	denotes	-
T13331	573-576	SO_EXT:0000771	denotes	QTL
T13332	641-644	SO_EXT:0000771	denotes	QTL
T13333	676-679	SO_EXT:0000771	denotes	QTL
T13334	735-738	SO_EXT:0000771	denotes	QTL
T13335	805-813	SO:0000860	denotes	syntenic
T13336	853-860	SO_EXT:0001026	denotes	genomic
T13337	876-881	NCBITaxon:9606	denotes	human
T13338	882-888	SO_EXT:0001026	denotes	genome
T13339	912-915	SO_EXT:0000771	denotes	QTL
T13340	969-972	SO_EXT:0000771	denotes	QTL
T13341	983-990	SO_EXT:0001023	denotes	alleles
T13342	1019-1026	SO_EXT:0001023	denotes	alleles
T13343	1043-1050	SO_EXT:0001023	denotes	alleles
T13344	1079-1086	SO_EXT:0001023	denotes	alleles
T13345	1106-1109	SO_EXT:0000771	denotes	QTL
T13346	1147-1152	SO_EXT:0000704	denotes	genes
T13347	1264-1267	SO_EXT:0000771	denotes	QTL
T13348	1346-1353	SO_EXT:0001026	denotes	genomic
T13349	1373-1376	SO_EXT:0000771	denotes	QTL
T13350	1377-1388	GO:0065007	denotes	controlling
T13351	1395-1403	GO:0042571	denotes	antibody
T13352	1414-1422	CHEBI_PR_EXT:collagen	denotes	collagen
T13353	1414-1425	PR_EXT:000003266	denotes	collagen II
T13354	1458-1461	SO_EXT:0000771	denotes	QTL
T13355	1474-1475	CHEBI_SO_EXT:base	denotes	b
T13356	1476-1483	SO_EXT:0001026	denotes	genomic
T13357	1509-1513	SO_EXT:0000704	denotes	gene
T13358	1533-1542	GO:0065007	denotes	regulates
T13359	1559-1570	GO:0065007	denotes	controlling
T13360	1581-1589	GO:0042571	denotes	antibody
T13361	1600-1608	CHEBI_PR_EXT:collagen	denotes	collagen
T13362	1600-1611	PR_EXT:000003266	denotes	collagen II
T13363	1618-1623	_FRAGMENT	denotes	Locus
T13364	1626-1639	GO_SO_EXT:chromosomal_part_or_position_or_region_or_site	denotes	on chromosome
T13365	1668-1676	GO:0065007	denotes	controls
T13366	1677-1687	CL:0000542	denotes	lymphocyte
T13367	1677-1701	GO:0046651	denotes	lymphocyte proliferation
T13368	1751-1755	_FRAGMENT	denotes	loci
T13369	1758-1771	GO_SO_EXT:chromosomal_part_or_position_or_region_or_site	denotes	on chromosome
T13370	1775-1783	GO:0065007	denotes	controls
T13371	1784-1794	CL:0000542	denotes	lymphocyte
T13372	1847-1851	SO_EXT:0000704	denotes	gene
T13373	1876-1879	SO_EXT:0000771	denotes	QTL
T13374	1914-1925	GO:0065007	denotes	controlling
T13375	2004-2008	SO_EXT:0000704	denotes	gene
T13376	2004-2019	GO:0010467	denotes	gene expression
T13377	2050-2056	UBERON:0004905	denotes	joints
T13378	2071-2077	UBERON:0000479	denotes	tissue
T13379	2134-2138	SO_EXT:0000704	denotes	gene
T13380	2134-2149	GO:0010467	denotes	gene expression
T13381	2153-2156	UBERON:0000029	denotes	LNs
T13382	2202-2206	SO_EXT:0000704	denotes	gene
T13383	2202-2217	GO:0010467	denotes	gene expression
T13384	2230-2233	UBERON:0000029	denotes	LNs
T13385	2242-2253	SO_EXT:0000704	denotes	genetically
T13386	2353-2362	GO:0065007	denotes	regulated
T13387	2363-2368	SO_EXT:0000704	denotes	genes
T13388	2446-2451	SO_EXT:0000704	denotes	genes
T13389	2472-2481	GO:0010467	denotes	expressed
T13390	2526-2536	CHEBI_GO_EXT:biological_process_or_quality_or_role	denotes	biological
T13391	2537-2546	GO_EXT:reaction_or_response	denotes	responses
T13392	2550-2553	UBERON:0000029	denotes	LNs
T13393	2622-2631	GO_EXT:reaction_or_response	denotes	responses
T13394	2775-2780	SO_EXT:0000704	denotes	genes
T13395	2811-2816	SO_EXT:0000704	denotes	genes
T13396	2830-2840	GO:0010467	denotes	expression
T13397	2924-2934	GO:0010467	denotes	expression
T13398	3003-3008	SO_EXT:0000704	denotes	genes
T13399	3025-3035	CL:0000542	denotes	lymphocyte
T13400	3025-3049	GO:0046651	denotes	lymphocyte proliferation
T13401	3025-3035	_FRAGMENT	denotes	lymphocyte
T13402	3054-3064	GO:0046649	denotes	activation
T13403	3082-3093	CL:0000542	denotes	lymphocytes
T13404	3222-3232	GO:0010467	denotes	expression
T13405	3279-3283	NCBITaxon:10088	denotes	mice
T13406	3325-3330	SO_EXT:0000704	denotes	genes
T13407	3346-3352	UBERON:0002405	denotes	immune
T13408	3346-3361	GO:0006955	denotes	immune response
T13409	3367-3378	GO_EXT:positive_regulation	denotes	upregulated
T13410	3484-3492	GO:0042571	denotes	antibody
T13411	3484-3501	GO:0016064	denotes	antibody response
T13412	3505-3513	CHEBI_PR_EXT:collagen	denotes	collagen
T13413	3505-3516	PR_EXT:000003266	denotes	collagen II
T13414	3681-3686	SO_EXT:0000704	denotes	genes
T13415	3726-3731	SO_EXT:0000704	denotes	genes
T13416	3766-3769	SO_EXT:0000771	denotes	QTL
T13417	3789-3793	SO_EXT:0000704	denotes	gene
T13418	3789-3804	GO:0010467	denotes	gene expression
T13419	3835-3842	SO_EXT:0001026	denotes	genomic
T13420	3867-3872	SO_EXT:0000704	denotes	genes
T13421	3889-3892	SO_EXT:0000771	denotes	QTL
T13422	3922-3935	SO_EXT:polymorphism	denotes	polymorphisms
T13423	3958-3963	SO_EXT:0000704	denotes	genes
T13424	3981-3984	SO_EXT:0000771	denotes	QTL
T13425	4019-4029	GO:0065007	denotes	regulating
T13426	4030-4034	SO_EXT:0000704	denotes	gene
T13427	4030-4045	GO:0010467	denotes	gene expression
T13428	4071-4076	SO_EXT:0000704	denotes	genes
T13429	4120-4126	PR_EXT:000003107	denotes	Mapk14
T13430	4140-4144	SO_EXT:0000704	denotes	gene
T13431	4173-4209	_FRAGMENT	denotes	p38 mitogen-activated protein kinase
T13432	4217-4222	PR_EXT:000003107	denotes	alpha
T13433	4173-4176	_FRAGMENT	denotes	p38
T13434	4211-4215	_FRAGMENT	denotes	MAPK
T13435	4177-4184	CHEBI_EXT:52290	denotes	mitogen
T13436	4177-4209	GO_PR_EXT:MAP_kinase	denotes	mitogen-activated protein kinase
T13437	4195-4202	CHEBI_PR_EXT:protein	denotes	protein
T13438	4211-4215	GO_PR_EXT:MAP_kinase	denotes	MAPK
T13439	4224-4233	GO:0065007	denotes	regulates
T13440	4238-4251	_FRAGMENT	denotes	production of
T13441	4272-4281	GO_EXT:cytokine_biosynthesis_or_production	denotes	cytokines
T13442	4272-4281	GO_EXT:0005125	denotes	cytokines
T13443	4291-4313	PR_EXT:tumor_necrosis_factor	denotes	tumour necrosis factor
T13444	4298-4306	GO_PATO_EXT:necrosis	denotes	necrosis
T13445	4318-4331	PR_EXT:000001091	denotes	interleukin-1
T13446	4348-4361	_FRAGMENT	denotes	inhibitors of
T13447	4366-4370	CHEBI_EXT:79091	denotes	MAPK
T13448	4362-4370	PR_EXT:000003106	denotes	p38 MAPK
T13449	4366-4370	GO_PR_EXT:MAP_kinase	denotes	MAPK
T13475	5440-5455	GO:0010467	denotes	gene expression
T13476	5515-5524	GO:0010467	denotes	expressed
T13477	5525-5530	SO_EXT:0000704	denotes	genes
T13478	5562-5572	GO:0010467	denotes	expression
T13479	5578-5582	SO_EXT:0000704	denotes	gene
T13480	5610-5616	SO_EXT:0001023	denotes	allele
T13450	4394-4398	NCBITaxon:10114	denotes	rats
T13451	4409-4417	PR_EXT:000003106	denotes	p38 MAPK
T13452	4413-4417	GO_PR_EXT:MAP_kinase	denotes	MAPK
T13453	4473-4479	PR_EXT:000002091	denotes	Stat5a
T13454	4493-4497	SO_EXT:0000704	denotes	gene
T13455	4526-4534	CHEBI:36357	denotes	molecule
T13456	4539-4547	CL_UBERON_EXT:lymphocyte_or_lymphoid_progenitor_or_system_or_tissue	denotes	lymphoid
T13457	4564-4579	GO_RO_EXT:developmental_differentiation_process	denotes	differentiation
T13458	4586-4592	PR_EXT:000002091	denotes	Stat5a
T13459	4603-4607	NCBITaxon:10088	denotes	mice
T13460	4677-4683	UBERON:0002405	denotes	immune
T13461	4694-4700	PR_EXT:000002091	denotes	Stat5a
T13462	4768-4771	PR_EXT:000001004	denotes	CD4
T13463	4772-4776	PR_EXT:000001380	denotes	CD25
T13464	4778-4788	GO:0065007	denotes	regulatory
T13465	4778-4795	CL:0000815	denotes	regulatory T cell
T13466	4791-4795	CL_GO_EXT:cell	denotes	cell
T13467	4878-4881	SO_EXT:0000771	denotes	QTL
T13468	4917-4922	SO_EXT:0000704	denotes	genes
T13469	5017-5024	NCBITaxon:33208	denotes	animals
T13470	5085-5091	SO_EXT:0001026	denotes	genome
T13471	5130-5133	SO_EXT:0000771	denotes	QTL
T13472	5332-5335	SO_EXT:0000771	denotes	QTL
T13473	5385-5392	NCBITaxon:33208	denotes	animals
T13474	5440-5444	SO_EXT:0000704	denotes	gene
R3522	T13434	T13433	_lexicallyChainedTo	MAPK,p38
R3523	T13441	T13440	_lexicallyChainedTo	cytokines,production of
R3524	T13447	T13446	_lexicallyChainedTo	MAPK,inhibitors of
R3517	T13364	T13363	_lexicallyChainedTo	on chromosome,Locus
R3518	T13369	T13368	_lexicallyChainedTo	on chromosome,loci
R3519	T13402	T13401	_lexicallyChainedTo	activation,lymphocyte
R3520	T13432	T13431	_lexicallyChainedTo	alpha,p38 mitogen-activated protein kinase
R3521	T13432	T13434	_lexicallyChainedTo	alpha,MAPK

2_test

Id	Subject	Object	Predicate	Lexical cue
17244351-2563713-4361140	273-275	2563713	denotes	26
17244351-15529344-4361141	1309-1311	15529344	denotes	10
17244351-17082620-4361142	1613-1615	17082620	denotes	31
17244351-12482389-4361143	2079-2081	12482389	denotes	15
17244351-11908948-4361144	2082-2084	11908948	denotes	16
17244351-15987489-4361145	2085-2087	15987489	denotes	21
17244351-15743466-4361146	2088-2090	15743466	denotes	22
17244351-12951578-4361147	4333-4335	12951578	denotes	32
17244351-13130488-4361148	4400-4402	13130488	denotes	33
17244351-12951578-4361149	4468-4470	12951578	denotes	32
17244351-16418296-4361150	4581-4583	16418296	denotes	34
17244351-14607901-4361151	4808-4810	14607901	denotes	35

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id	Subject	Object	Predicate	Lexical cue
T13213	1264-1267	SO:0000771	denotes	QTL
T13214	1346-1353	SO:0001026	denotes	genomic
T13215	1373-1376	SO:0000771	denotes	QTL
T13216	1377-1388	GO:0065007	denotes	controlling
T13217	1395-1403	GO:0042571	denotes	antibody
T13218	1414-1425	PR:000003266	denotes	collagen II
T13219	1458-1461	SO:0000771	denotes	QTL
T13220	1476-1483	SO:0001026	denotes	genomic
T13221	1509-1513	SO:0000704	denotes	gene
T13222	1533-1542	GO:0065007	denotes	regulates
T13223	1559-1570	GO:0065007	denotes	controlling
T13224	1581-1589	GO:0042571	denotes	antibody
T13225	1600-1611	PR:000003266	denotes	collagen II
T13226	1668-1676	GO:0065007	denotes	controls
T13227	1677-1687	CL:0000542	denotes	lymphocyte
T13228	1677-1701	GO:0046651	denotes	lymphocyte proliferation
T13229	1775-1783	GO:0065007	denotes	controls
T13230	1784-1794	CL:0000542	denotes	lymphocyte
T13191	83-86	SO:0000771	denotes	QTL
T13192	118-121	SO:0000771	denotes	QTL
T13193	358-361	SO:0000771	denotes	QTL
T13194	392-397	SO:0000704	denotes	genes
T13195	499-501	PR:000004904	denotes	C5
T13196	524-526	PR:000004904	denotes	C5
T13197	573-576	SO:0000771	denotes	QTL
T13198	641-644	SO:0000771	denotes	QTL
T13199	676-679	SO:0000771	denotes	QTL
T13200	735-738	SO:0000771	denotes	QTL
T13201	805-813	SO:0000860	denotes	syntenic
T13202	853-860	SO:0001026	denotes	genomic
T13203	876-881	NCBITaxon:9606	denotes	human
T13204	882-888	SO:0001026	denotes	genome
T13205	912-915	SO:0000771	denotes	QTL
T13206	969-972	SO:0000771	denotes	QTL
T13207	983-990	SO:0001023	denotes	alleles
T13208	1019-1026	SO:0001023	denotes	alleles
T13209	1043-1050	SO:0001023	denotes	alleles
T13210	1079-1086	SO:0001023	denotes	alleles
T13211	1106-1109	SO:0000771	denotes	QTL
T13212	1147-1152	SO:0000704	denotes	genes
T13231	1847-1851	SO:0000704	denotes	gene
T13232	1876-1879	SO:0000771	denotes	QTL
T13233	1914-1925	GO:0065007	denotes	controlling
T13234	2004-2008	SO:0000704	denotes	gene
T13235	2004-2019	GO:0010467	denotes	gene expression
T13236	2050-2056	UBERON:0004905	denotes	joints
T13237	2071-2077	UBERON:0000479	denotes	tissue
T13238	2134-2138	SO:0000704	denotes	gene
T13239	2134-2149	GO:0010467	denotes	gene expression
T13240	2153-2156	UBERON:0000029	denotes	LNs
T13241	2202-2206	SO:0000704	denotes	gene
T13242	2202-2217	GO:0010467	denotes	gene expression
T13243	2230-2233	UBERON:0000029	denotes	LNs
T13244	2242-2253	SO:0000704	denotes	genetically
T13245	2353-2362	GO:0065007	denotes	regulated
T13246	2363-2368	SO:0000704	denotes	genes
T13247	2446-2451	SO:0000704	denotes	genes
T13248	2472-2481	GO:0010467	denotes	expressed
T13249	2550-2553	UBERON:0000029	denotes	LNs
T13250	2775-2780	SO:0000704	denotes	genes
T13251	2811-2816	SO:0000704	denotes	genes
T13252	2830-2840	GO:0010467	denotes	expression
T13253	2924-2934	GO:0010467	denotes	expression
T13254	3003-3008	SO:0000704	denotes	genes
T13255	3025-3035	CL:0000542	denotes	lymphocyte
T13256	3025-3049	GO:0046651	denotes	lymphocyte proliferation
T13257	3025-3035	_FRAGMENT	denotes	lymphocyte
T13258	3054-3064	GO:0046649	denotes	activation
T13259	3082-3093	CL:0000542	denotes	lymphocytes
T13260	3222-3232	GO:0010467	denotes	expression
T13261	3279-3283	NCBITaxon:10088	denotes	mice
T13262	3325-3330	SO:0000704	denotes	genes
T13263	3346-3352	UBERON:0002405	denotes	immune
T13264	3346-3361	GO:0006955	denotes	immune response
T13265	3484-3492	GO:0042571	denotes	antibody
T13266	3484-3501	GO:0016064	denotes	antibody response
T13267	3505-3516	PR:000003266	denotes	collagen II
T13268	3681-3686	SO:0000704	denotes	genes
T13269	3726-3731	SO:0000704	denotes	genes
T13270	3766-3769	SO:0000771	denotes	QTL
T13271	3789-3793	SO:0000704	denotes	gene
T13272	3789-3804	GO:0010467	denotes	gene expression
T13273	3835-3842	SO:0001026	denotes	genomic
T13274	3867-3872	SO:0000704	denotes	genes
T13275	3889-3892	SO:0000771	denotes	QTL
T13276	3958-3963	SO:0000704	denotes	genes
T13277	3981-3984	SO:0000771	denotes	QTL
T13278	4019-4029	GO:0065007	denotes	regulating
T13279	4030-4034	SO:0000704	denotes	gene
T13280	4030-4045	GO:0010467	denotes	gene expression
T13281	4071-4076	SO:0000704	denotes	genes
T13282	4120-4126	PR:000003107	denotes	Mapk14
T13283	4140-4144	SO:0000704	denotes	gene
T13284	4173-4209	_FRAGMENT	denotes	p38 mitogen-activated protein kinase
T13285	4217-4222	PR:000003107	denotes	alpha
T13286	4173-4176	_FRAGMENT	denotes	p38
T13287	4211-4215	_FRAGMENT	denotes	MAPK
T13288	4177-4184	CHEBI:52290	denotes	mitogen
T13289	4224-4233	GO:0065007	denotes	regulates
T13290	4318-4331	PR:000001091	denotes	interleukin-1
T13291	4348-4361	_FRAGMENT	denotes	inhibitors of
T13292	4366-4370	CHEBI:79091	denotes	MAPK
T13293	4362-4370	PR:000003106	denotes	p38 MAPK
T13294	4394-4398	NCBITaxon:10114	denotes	rats
T13295	4409-4417	PR:000003106	denotes	p38 MAPK
T13296	4473-4479	PR:000002091	denotes	Stat5a
T13297	4493-4497	SO:0000704	denotes	gene
T13298	4526-4534	CHEBI:36357	denotes	molecule
T13299	4586-4592	PR:000002091	denotes	Stat5a
T13300	4603-4607	NCBITaxon:10088	denotes	mice
T13301	4677-4683	UBERON:0002405	denotes	immune
T13302	4694-4700	PR:000002091	denotes	Stat5a
T13303	4768-4771	PR:000001004	denotes	CD4
T13304	4772-4776	PR:000001380	denotes	CD25
T13305	4778-4788	GO:0065007	denotes	regulatory
T13306	4778-4795	CL:0000815	denotes	regulatory T cell
T13307	4878-4881	SO:0000771	denotes	QTL
T13308	4917-4922	SO:0000704	denotes	genes
T13309	5017-5024	NCBITaxon:33208	denotes	animals
T13310	5085-5091	SO:0001026	denotes	genome
T13311	5130-5133	SO:0000771	denotes	QTL
T13312	5332-5335	SO:0000771	denotes	QTL
T13313	5385-5392	NCBITaxon:33208	denotes	animals
T13314	5440-5444	SO:0000704	denotes	gene
T13315	5440-5455	GO:0010467	denotes	gene expression
T13316	5515-5524	GO:0010467	denotes	expressed
T13317	5525-5530	SO:0000704	denotes	genes
T13318	5562-5572	GO:0010467	denotes	expression
T13319	5578-5582	SO:0000704	denotes	gene
T13320	5610-5616	SO:0001023	denotes	allele
R3512	T13258	T13257	_lexicallyChainedTo	activation,lymphocyte
R3513	T13285	T13284	_lexicallyChainedTo	alpha,p38 mitogen-activated protein kinase
R3514	T13285	T13287	_lexicallyChainedTo	alpha,MAPK
R3515	T13287	T13286	_lexicallyChainedTo	MAPK,p38
R3516	T13292	T13291	_lexicallyChainedTo	MAPK,inhibitors of

PMC:1860061 / 19048-24788 JSONTXT

Annnotations TAB JSON ListView MergeView

craft-sa-dev

craft-ca-core-ex-dev

2_test

craft-ca-core-dev

PMC:1860061 / 19048-24788 JSON TXT