Confocal analysis of Pygo2 wild-type, heterozygous, and null E18.5 kidneys on the Pygo1 null background. Genotype Ureteric tip Condensing mesenchyme Ureteric tips/mm2 SD n Mesenchyme condensate size (μm) SD n Pygo2 +/+ 196 8.36 3 16.2 1.09 3 Pygo2 +/- 191 11.6 7 15.6 1.18 5 Pygo2 -/- 147* 12.2 7 20.9 * 1.12 5 *Significant change (P < 0.01) between the three groups. SD, Standard deviation; n, number Confocal analysis also