Based upon the distances in the phylogenetic tree we partitioned the fourteen species into four clades, the Vibrionales clade, the Pasteurellales clade, P. mirabilis (by itself), and the remaining Enterobacteriales (henceforth, the Enterobacteriales clade). To evaluate the trade-off between sensitivity and specificity, we ran PhyloScan using the full-strength Crp motif; we scanned the full-strength-Crp-sites sequence data (positive data) and the no-sites sequence data (negative data). Likewise, we ran PhyloScan using the 1/2-strength Crp motif, scanning the 1/2-strength sequence data (positive data) and the no-sites sequence data (negative data); we also ran PhyloScan using the 1/3-strength Crp motif, scanning the 1/3-strength sequence data (positive data) and the no-sites sequence data (negative data).