ℐ x j = f x j ln ⁡ ( f x j ) − p x ln ⁡ ( p x ) , ℐ j = ∑ x ∈ Σ DNA ℐ x j , ℐ = ∑ j = 1 | ℳ | ℐ j       ( 2 ) MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBamrtHrhAL1wy0L2yHvtyaeHbnfgDOvwBHrxAJfwnaebbnrfifHhDYfgasaacH8akY=wiFfYdH8Gipec8Eeeu0xXdbba9frFj0=OqFfea0dXdd9vqai=hGuQ8kuc9pgc9s8qqaq=dirpe0xb9q8qiLsFr0=vr0=vr0dc8meaabaqaciaacaGaaeqabaWaaeGaeaaakeaafaqabeqadaaabaacdaGae8heHK0aaSbaaSqaaiabdIha4jabdQgaQbqabaGccqGH9aqpcqWGMbGzdaWgaaWcbaGaemiEaGNaemOAaOgabeaakiGbcYgaSjabc6gaUjabcIcaOiabdAgaMnaaBaaaleaacqWG4baEcqWGQbGAaeqaaOGaeiykaKIaeyOeI0IaemiCaa3aaSbaaSqaaiabdIha4bqabaGccyGGSbaBcqGGUbGBcqGGOaakcqWGWbaCdaWgaaWcbaGaemiEaGhabeaakiabcMcaPiabcYcaSaqaaiab=brijnaaBaaaleaacqWGQbGAaeqaaOGaeyypa0ZaaabuaeaacqWFqessdaWgaaWcbaGaemiEaGNaemOAaOgabeaakiabcYcaSaWcbaGaemiEaGNaeyicI4Saeu4Odm1aaSbaaWqaaiabbseaejabb6eaojabbgeabbqabaaaleqaniabggHiLdaakeaacqWFqesscqGH9aqpdaaeWbqaaiab=brijnaaBaaaleaacqWGQbGAaeqaaaqaaiabdQgaQjabg2da9iabigdaXaqaaiabcYha8jab=ntinjabcYha8bqdcqGHris5aaaakiaaxMaacaWLjaWaaeWaaeaacqaIYaGmaiaawIcacaGLPaaaaaa@79E3@