f x j   = ℳ x j   + p x   ∑ y ∈ Σ DNA     ( ℳ y j   + p y  )     ,   W ′  x j   = ln ⁡ ( f x j    p x     )            ( 1 )    MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBamrtHrhAL1wy0L2yHvtyaeHbnfgDOvwBHrxAJfwnaebbnrfifHhDYfgasaacH8akY=wiFfYdH8Gipec8Eeeu0xXdbba9frFj0=OqFfea0dXdd9vqai=hGuQ8kuc9pgc9s8qqaq=dirpe0xb9q8qiLsFr0=vr0=vr0dc8meaabaqaciaacaGaaeqabaWaaeGaeaaakeaafaqabeqacaaabaGaemOzay2aaSbaaSqaaiabdIha4jabdQgaQbqabaGccqGH9aqpdaWcaaqaaGWaaiab=ntinnaaBaaaleaacqWG4baEcqWGQbGAaeqaaOGaey4kaSIaemiCaa3aaSbaaSqaaiabdIha4bqabaaakeaadaaeqaqaaiabcIcaOiab=ntinnaaBaaaleaacqWG5bqEcqWGQbGAaeqaaOGaey4kaSIaemiCaa3aaSbaaSqaaiabdMha5bqabaGccqGGPaqkaSqaaiabdMha5jabgIGiolabfo6atnaaBaaameaacqqGebarcqqGobGtcqqGbbqqaeqaaaWcbeqdcqGHris5aaaakiabcYcaSaqaaiqb=zr8xzaafaWaaSbaaSqaaiabdIha4jabdQgaQbqabaGccqGH9aqpcyGGSbaBcqGGUbGBdaqadaqaamaalaaabaGaemOzay2aaSbaaSqaaiabdIha4jabdQgaQbqabaaakeaacqWGWbaCdaWgaaWcbaGaemiEaGhabeaaaaaakiaawIcacaGLPaaaaaGaaCzcaiaaxMaadaqadaqaaiabigdaXaGaayjkaiaawMcaaaaa@6E55@