Table 1 Number of reference alignments and average Structure Conservation Index (SCI) for each alignment of k sequences. k2 k3 k5 k7 k10 k15 total no. aln. 8976 (118) 4835 2405 (481) 1426 845 504 18990 ∅ SCI 0.95 (1.05) 0.92 0.91 (0.87) 0.90 0.89 0.89 0.93 Values for the previously used data-set1 [22] are given in brackets.