Program/Option k2 k3 k5 k7 k10 k15 CLUSTALW (default) 8 7 8 8 7 7 CLUSTALW (optimized) 6 6 7 7 6 6 MAFFT (FFT-NS-2) 2 4 4 4 5 5 MAFFT (G-INS-i) 1 1 1 1 1 1 MUSCLE 3 3 3 2 2 2 PCMA 9 10 10 10 10 10 POA 7 8 9 9 9 9 PROALIGN 5 5 6 6 8 8 PROBCONSRNA 4 2 2 3 3 4 PRRN 10 9 5 5 4 3