Table 3 Comparison of the HSE- and CN measures for various proteins. Residues Measure < 7 Å RMSD < 6 Å RMSD < 5 Å RMSD < 4 Å RMSD < 3 Å RMSD < 2 Å RMSD lowest RMSD lowest energy Human Endothelin (1EDN) 21 CN 100 100 98 60 18 0 2.09 0.00 HSE 100 100 100 93 65 37 0.88 0.00 Tryptophan Zipper 1(1LE0) 13 CN 100 100 100 100 100 22 1.38 0.00 HSE 100 100 100 100 100 67 0.95 0.00 Third Zinc Finger (1SRK) 35 CN 60 42 17 (1SRK) 1 0 0 3.52 0.00 HSE 56 33 13 5 0 0 3.02 0.33 Mu-Conotoxin GIIA (1TCH) 23 CN 100 100 97 63 23 5 1.58 0.00 HSE 100 100 100 97 61 38 0.91 0.00 Pandinus Toxin (2PTA) 35 CN 59 32 14 3 0 0 3.17 0.00 HSE 58 44 17 11 2 0 2.66 0.33