Lattice models are widely used for studying the fundamental properties of protein structure[17]. Such models have for example provided invaluable insights on topics such as the validity of pairwise energy functions[18], the evolution of protein superfamilies[19] and the importance of local structural bias in the determination of a protein's fold[20]. Many lattice models have been proposed and evaluated in the literature. Not surprisingly, experiments show a high correlation between the number of basis vectors of a lattice and its ability to represent a protein backbone[21,22]. When deciding on a lattice model, one must always consider the trade-off between the reduction of the conformational space and the quality of the structure representation. Therefore, in section Lattice experiments we evaluate four different lattices of various complexity: The SCC lattice, the FCC lattice and two high coordination (HC) lattices with 54 and 390 basis vectors, respectively.