Why not seeding at 1/2
In the original CGR proposition [1] the mid coordinate, 1/2, is invariably used as the initial position. Because this position cannot be mapped back to a real sequence this at first appeared as a reasonable proposition even if not fundamentally superior to any of the other boundary positions such as 0 and 1. However, seeding all iterations equally causes an artifactual conservation of the beginning of the sequence which will bias sequence entropy calculations based on map coordinates [15], particularly for small sequences: the first iteration can only produce two coordinates, 1/4 or 3/4, the second iteration will produce one of 4 possibilities: 1/8, 3/8, 5/8 or 7/8, etc. This will cause some extent of artfactual high density at those positions.