Table 3 Scoring method evaluation in terms of performance coefficient in biased-composition simulated data. Performance of LP/DEE in biased-composition simulated data. The first column identifies the TF dataset. The second column measures the degree of conservation of the known motif, as measured by average per-column information content [44]. The rest of the columns list the nucleotide performance coefficient of the LP/DEE method with the probability of base G indicated in the column heading and the frequencies of all other bases split equally. TF IC Bias 0.25 0.5 0.75 0.9 araC 1.00041 0.8113 0.9592 0.9592 0.9592 cpxR 1.17034 1.0000 0.8261 0.9811 0.9811 dnaA 1.45351 1.0000 0.7647 0.7647 1.0000 galR 1.34756 0.8824 0.8824 1.0000 1.0000 narP 1.40273 1.0000 1.0000 1.0000 1.0000