so as to maximize the minimal distance to a Hopf bifurcation with respect to a reference point (α = 102.5, β = 100). Figure 9 shows the initial bifurcation diagram and the computed minimal distance from the reference point. The result of the inverse bifurcation analysis shows that the optimum solution is found at (δ, h) = (10-4, 2); thus, the inequality constraints are active equality constraints. Moreover, the signs of the Lagrange multipliers for the inequality constraints show that the (local) optimum distance to the Hopf bifurcation manifold increases if the upper bound hupp is increased and/or the lower bound δlow is decreased. Figure 10 shows the bifurcation diagram with the optimized parameters.