PMC:1564426 / 38216-38542 JSONTXT

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    craft-ca-core-ex-dev

    {"project":"craft-ca-core-ex-dev","denotations":[{"id":"T19028","span":{"begin":43,"end":46},"obj":"PR_EXT:000004122"},{"id":"T19029","span":{"begin":55,"end":62},"obj":"UBERON:0000479"},{"id":"T19030","span":{"begin":74,"end":96},"obj":"UBERON:0001555"},{"id":"T19031","span":{"begin":104,"end":108},"obj":"UBERON:0000104"},{"id":"T19032","span":{"begin":112,"end":119},"obj":"NCBITaxon:33208"},{"id":"T19033","span":{"begin":142,"end":151},"obj":"UBERON:0000922"},{"id":"T19034","span":{"begin":152,"end":161},"obj":"GO_EXT:fatality_or_lethality"},{"id":"T19035","span":{"begin":178,"end":181},"obj":"PR_EXT:000004122"},{"id":"T19036","span":{"begin":210,"end":215},"obj":"NCBITaxon:10088"},{"id":"T19037","span":{"begin":246,"end":252},"obj":"SO_EXT:0001023"},{"id":"T19038","span":{"begin":256,"end":259},"obj":"PR_EXT:000004122"},{"id":"T19039","span":{"begin":261,"end":264},"obj":"PR_EXT:000004122"},{"id":"T19040","span":{"begin":278,"end":282},"obj":"SO_EXT:0000147"},{"id":"T19041","span":{"begin":293,"end":296},"obj":"PR_EXT:000004122"},{"id":"T19042","span":{"begin":300,"end":307},"obj":"SO:0000357"},{"id":"T19043","span":{"begin":311,"end":325},"obj":"SO_EXT:0000346"}],"text":" To gain more insights into the effects of Apc loss in tissues other than gastrointestinal tract during life of animals and to circumvent the embryonic lethality associated with Apc nullizygosity, we created a mouse strain carrying a conditional allele of Apc (ApcCKO) in which exon 14 of the Apc is flanked by loxP sequences."}

    craft-ca-core-dev

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    craft-sa-dev

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To gain more insights into the effects of Apc loss in tissues other than gastrointestinal tract during life of animals and to circumvent the embryonic lethality associated with Apc nullizygosity, we created a mouse strain carrying a conditional allele of Apc (ApcCKO) in which exon 14 of the Apc is flanked by loxP sequences."}