The use of the c-value is an important parameter for biological applications. Again we think of the situation of reconstructing phylogenetic trees from sequences reported from a BLAST run. Here different c parameters can be used to either optimize the length of the overlaps or the size of the maximal cliques. A model where the factor c is not a tolerance relative to the length but a fixed constant independent of the length might be of some biological relevance. An extension towards such a model or even a mixture seems plausible.