PMC:1472690 / 23739-24145
Annnotations
pmc-enju-pas
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T12851 | 403-405 | NN | denotes | GP |
T12850 | 400-402 | IN | denotes | by |
T12849 | 390-399 | NN | denotes | phenotype |
T12848 | 372-389 | JJ | denotes | anti-inflammatory |
T12847 | 369-371 | DT | denotes | an |
T12846 | 366-368 | TO | denotes | to |
T12845 | 357-365 | VB | denotes | switched |
T12844 | 354-356 | VB | denotes | is |
T12843 | 343-353 | NN | denotes | leukocytes |
T12842 | 337-342 | JJ | denotes | human |
T12841 | 334-336 | IN | denotes | of |
T12840 | 323-333 | NN | denotes | expression |
T12839 | 314-322 | NN | denotes | cytokine |
T12838 | 310-313 | CC | denotes | and |
T12837 | 302-309 | NN | denotes | binding |
T12836 | 295-301 | NN | denotes | factor |
T12835 | 281-294 | NN | denotes | transcription |
T12834 | 264-280 | JJ | denotes | pro-inflammatory |
T12833 | 254-263 | NN | denotes | signaling |
T12832 | 250-253 | CC | denotes | and |
T12831 | 238-249 | NN | denotes | recognition |
T12830 | 235-237 | IN | denotes | of |
T12829 | 224-234 | JJ | denotes | downstream |
T12828 | 219-223 | IN | denotes | that |
T12827 | 210-218 | NN | denotes | evidence |
T12826 | 204-209 | JJ | denotes | novel |
T12825 | 195-203 | VB | denotes | provides |
T12824 | 189-194 | NN | denotes | study |
T12823 | 185-188 | PRP-DOLLAR- | denotes | Our |
T12822 | 182-183 | -RRB- | denotes | ] |
T12821 | 177-182 | CD | denotes | 22,37 |
T12820 | 176-177 | -LRB- | denotes | [ |
T12819 | 161-175 | NN | denotes | PI3K-signaling |
T12818 | 158-160 | TO | denotes | to |
T12817 | 152-157 | NN | denotes | NFκB- |
T12816 | 147-151 | IN | denotes | from |
T12815 | 141-146 | NN | denotes | shift |
T12814 | 135-140 | JJ | denotes | rapid |
T12813 | 133-134 | DT | denotes | a |
T12812 | 129-132 | IN | denotes | via |
T12811 | 127-128 | -COMMA- | denotes | , |
T12810 | 123-127 | NN | denotes | part |
T12809 | 120-122 | IN | denotes | in |
T12808 | 118-119 | -COMMA- | denotes | , |
T12807 | 108-118 | NN | denotes | mechanisms |
T12806 | 97-107 | JJ | denotes | protective |
T12805 | 93-96 | PRP-DOLLAR- | denotes | its |
T12804 | 84-92 | VB | denotes | mediates |
T12803 | 81-83 | NN | denotes | GP |
T12802 | 76-80 | IN | denotes | like |
T12801 | 61-75 | NN | denotes | β-1→3-D-glucan |
T12800 | 59-60 | DT | denotes | a |
T12799 | 54-58 | IN | denotes | that |
T12798 | 46-53 | VB | denotes | suggest |
T12797 | 39-45 | NN | denotes | injury |
T12796 | 28-38 | JJ | denotes | myocardial |
T12795 | 24-27 | CC | denotes | and |
T12794 | 17-23 | NN | denotes | sepsis |
T12793 | 14-16 | IN | denotes | of |
T12792 | 7-13 | NN | denotes | models |
T12791 | 0-6 | NN | denotes | Animal |
R7949 | T12792 | T12791 | arg1Of | models,Animal |
R7950 | T12792 | T12793 | arg1Of | models,of |
R7951 | T12792 | T12798 | arg1Of | models,suggest |
R7952 | T12794 | T12795 | arg1Of | sepsis,and |
R7953 | T12795 | T12793 | arg2Of | and,of |
R7954 | T12797 | T12795 | arg2Of | injury,and |
R7955 | T12797 | T12796 | arg1Of | injury,myocardial |
R7956 | T12801 | T12800 | arg1Of | β-1→3-D-glucan,a |
R7957 | T12801 | T12802 | arg1Of | β-1→3-D-glucan,like |
R7958 | T12801 | T12804 | arg1Of | β-1→3-D-glucan,mediates |
R7959 | T12803 | T12802 | arg2Of | GP,like |
R7960 | T12804 | T12798 | arg2Of | mediates,suggest |
R7961 | T12804 | T12799 | arg1Of | mediates,that |
R7962 | T12804 | T12808 | arg1Of | mediates,"," |
R7963 | T12804 | T12809 | arg1Of | mediates,in |
R7964 | T12804 | T12811 | arg1Of | mediates,"," |
R7965 | T12804 | T12812 | arg1Of | mediates,via |
R7966 | T12804 | T12820 | arg1Of | mediates,[ |
R7967 | T12807 | T12804 | arg2Of | mechanisms,mediates |
R7968 | T12807 | T12805 | arg1Of | mechanisms,its |
R7969 | T12807 | T12806 | arg1Of | mechanisms,protective |
R7970 | T12810 | T12809 | arg2Of | part,in |
R7971 | T12815 | T12812 | arg2Of | shift,via |
R7972 | T12815 | T12813 | arg1Of | shift,a |
R7973 | T12815 | T12814 | arg1Of | shift,rapid |
R7974 | T12815 | T12816 | arg1Of | shift,from |
R7975 | T12815 | T12818 | arg1Of | shift,to |
R7976 | T12817 | T12816 | arg2Of | NFκB-,from |
R7977 | T12819 | T12818 | arg2Of | PI3K-signaling,to |
R7978 | T12821 | T12820 | arg2Of | "22,37",[ |
R7979 | T12822 | T12820 | arg3Of | ],[ |
R7980 | T12824 | T12823 | arg1Of | study,Our |
R7981 | T12824 | T12825 | arg1Of | study,provides |
R7982 | T12825 | T12832 | arg1Of | provides,and |
R7983 | T12827 | T12825 | arg2Of | evidence,provides |
R7984 | T12827 | T12826 | arg1Of | evidence,novel |
R7985 | T12827 | T12829 | arg1Of | evidence,downstream |
R7986 | T12829 | T12828 | arg1Of | downstream,that |
R7987 | T12829 | T12830 | arg1Of | downstream,of |
R7988 | T12831 | T12830 | arg2Of | recognition,of |
R7989 | T12837 | T12833 | arg1Of | binding,signaling |
R7990 | T12837 | T12834 | arg1Of | binding,pro-inflammatory |
R7991 | T12837 | T12835 | arg1Of | binding,transcription |
R7992 | T12837 | T12836 | arg1Of | binding,factor |
R7993 | T12837 | T12838 | arg1Of | binding,and |
R7994 | T12838 | T12844 | arg1Of | and,is |
R7995 | T12838 | T12845 | arg2Of | and,switched |
R7996 | T12840 | T12838 | arg2Of | expression,and |
R7997 | T12840 | T12839 | arg1Of | expression,cytokine |
R7998 | T12840 | T12841 | arg1Of | expression,of |
R7999 | T12843 | T12841 | arg2Of | leukocytes,of |
R8000 | T12843 | T12842 | arg1Of | leukocytes,human |
R8001 | T12845 | T12832 | arg2Of | switched,and |
R8002 | T12845 | T12844 | arg2Of | switched,is |
R8003 | T12845 | T12846 | arg1Of | switched,to |
R8004 | T12849 | T12846 | arg2Of | phenotype,to |
R8005 | T12849 | T12847 | arg1Of | phenotype,an |
R8006 | T12849 | T12848 | arg1Of | phenotype,anti-inflammatory |
R8007 | T12849 | T12850 | arg1Of | phenotype,by |
R8008 | T12851 | T12850 | arg2Of | GP,by |
GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T11910 | 281-294 | http://purl.obolibrary.org/obo/GO_0006351 | denotes | transcription |
T11901 | 254-263 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
T11900 | 166-175 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
T11899 | 161-175 | http://purl.obolibrary.org/obo/GO_0014065 | denotes | PI3K-signaling |
T11892 | 161-165 | http://purl.obolibrary.org/obo/GO_0016303 | denotes | PI3K |
GO-MF
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T12549 | 302-322 | http://purl.obolibrary.org/obo/GO_0019955 | denotes | binding and cytokine |
T12526 | 302-309 | http://purl.obolibrary.org/obo/GO_0005488 | denotes | binding |
T12519 | 161-165 | http://purl.obolibrary.org/obo/GO_0016303 | denotes | PI3K |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T11852 | 185-406 | Sentence | denotes | Our study provides novel evidence that downstream of recognition and signaling pro-inflammatory transcription factor binding and cytokine expression of human leukocytes is switched to an anti-inflammatory phenotype by GP. |
T11851 | 0-184 | Sentence | denotes | Animal models of sepsis and myocardial injury suggest that a β-1→3-D-glucan like GP mediates its protective mechanisms, in part, via a rapid shift from NFκB- to PI3K-signaling [22,37]. |
T178 | 0-184 | Sentence | denotes | Animal models of sepsis and myocardial injury suggest that a β-1→3-D-glucan like GP mediates its protective mechanisms, in part, via a rapid shift from NFκB- to PI3K-signaling [22,37]. |
T179 | 185-406 | Sentence | denotes | Our study provides novel evidence that downstream of recognition and signaling pro-inflammatory transcription factor binding and cytokine expression of human leukocytes is switched to an anti-inflammatory phenotype by GP. |
ICD10
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T12518 | 39-45 | http://purl.bioontology.org/ontology/ICD10/T14.9 | denotes | injury |
bionlp-st-ge-2016-test-ihmc
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T16911 | 161-183 | Protein | denotes | PI3K-signaling [22,37] |
T16893 | 403-405 | Protein | denotes | GP |
T16872 | 334-353 | Entity | denotes | of human leukocytes |
T16766 | 314-322 | Protein | denotes | cytokine |
T16765 | 81-83 | Protein | denotes | GP |
T16695 | 152-157 | Protein | denotes | NFκB- |
bionlp-st-ge-2016-spacy-parsed
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T14880 | 405-406 | . | denotes | . |
T14879 | 403-405 | NNP | denotes | GP |
T14878 | 400-402 | IN | denotes | by |
T14877 | 390-399 | NN | denotes | phenotype |
T14876 | 372-389 | JJ | denotes | anti-inflammatory |
T14875 | 369-371 | DT | denotes | an |
T14874 | 366-368 | TO | denotes | to |
T14873 | 357-365 | VBN | denotes | switched |
T14872 | 354-356 | VBZ | denotes | is |
T14871 | 343-353 | NNS | denotes | leukocytes |
T14870 | 337-342 | JJ | denotes | human |
T14869 | 334-336 | IN | denotes | of |
T14868 | 323-333 | NN | denotes | expression |
T14867 | 314-322 | JJ | denotes | cytokine |
T14866 | 310-313 | CC | denotes | and |
T14865 | 302-309 | JJ | denotes | binding |
T14864 | 295-301 | NN | denotes | factor |
T14863 | 281-294 | NN | denotes | transcription |
T14862 | 264-280 | JJ | denotes | pro-inflammatory |
T14861 | 254-263 | VBG | denotes | signaling |
T14860 | 250-253 | CC | denotes | and |
T14859 | 238-249 | NN | denotes | recognition |
T14858 | 235-237 | IN | denotes | of |
T14857 | 224-234 | JJ | denotes | downstream |
T14856 | 219-223 | IN | denotes | that |
T14855 | 210-218 | NN | denotes | evidence |
T14854 | 204-209 | JJ | denotes | novel |
T14853 | 195-203 | VBZ | denotes | provides |
T14852 | 189-194 | NN | denotes | study |
T14851 | 185-188 | PRP$ | denotes | Our |
T14850 | 183-184 | . | denotes | . |
T14849 | 182-183 | NNP | denotes | ] |
T14848 | 177-182 | CD | denotes | 22,37 |
T14847 | 176-177 | NNP | denotes | [ |
T14846 | 161-175 | JJ | denotes | PI3K-signaling |
T14845 | 158-160 | TO | denotes | to |
T14844 | 156-157 | : | denotes | - |
T14843 | 152-156 | NNP | denotes | NFκB |
T14842 | 147-151 | IN | denotes | from |
T14841 | 141-146 | NN | denotes | shift |
T14840 | 135-140 | JJ | denotes | rapid |
T14839 | 133-134 | DT | denotes | a |
T14838 | 129-132 | IN | denotes | via |
T14837 | 127-128 | , | denotes | , |
T14836 | 123-127 | NN | denotes | part |
T14835 | 120-122 | IN | denotes | in |
T14834 | 118-119 | , | denotes | , |
T14833 | 108-118 | NNS | denotes | mechanisms |
T14832 | 97-107 | JJ | denotes | protective |
T14831 | 93-96 | PRP$ | denotes | its |
T14830 | 84-92 | VBZ | denotes | mediates |
T14829 | 81-83 | NNP | denotes | GP |
T14828 | 76-80 | IN | denotes | like |
T14827 | 65-75 | NN | denotes | 3-D-glucan |
T14826 | 64-65 | NN | denotes | → |
T14825 | 61-64 | JJ | denotes | β-1 |
T14824 | 59-60 | DT | denotes | a |
T14823 | 54-58 | IN | denotes | that |
T14822 | 46-53 | VBP | denotes | suggest |
T14821 | 39-45 | NN | denotes | injury |
T14820 | 28-38 | JJ | denotes | myocardial |
T14819 | 24-27 | CC | denotes | and |
T14818 | 17-23 | NN | denotes | sepsis |
T14817 | 14-16 | IN | denotes | of |
T14816 | 7-13 | NNS | denotes | models |
T14815 | 0-6 | NNP | denotes | Animal |
R9732 | T14815 | T14816 | compound | Animal,models |
R9733 | T14816 | T14822 | nsubj | models,suggest |
R9735 | T14817 | T14816 | prep | of,models |
R9736 | T14818 | T14817 | pobj | sepsis,of |
R9737 | T14819 | T14818 | cc | and,sepsis |
R9739 | T14820 | T14821 | amod | myocardial,injury |
R9740 | T14821 | T14818 | conj | injury,sepsis |
R9741 | T14822 | T14822 | ROOT | suggest,suggest |
R9742 | T14823 | T14830 | mark | that,mediates |
R9743 | T14824 | T14827 | det | a,3-D-glucan |
R9744 | T14825 | T14827 | amod | β-1,3-D-glucan |
R9745 | T14826 | T14827 | compound | →,3-D-glucan |
R9746 | T14827 | T14830 | nsubj | 3-D-glucan,mediates |
R9747 | T14828 | T14830 | mark | like,mediates |
R9748 | T14829 | T14830 | nsubj | GP,mediates |
R9749 | T14830 | T14822 | ccomp | mediates,suggest |
R9750 | T14831 | T14833 | poss | its,mechanisms |
R9751 | T14832 | T14833 | amod | protective,mechanisms |
R9752 | T14833 | T14830 | dobj | mechanisms,mediates |
R9753 | T14834 | T14833 | punct | ",",mechanisms |
R9754 | T14835 | T14830 | prep | in,mediates |
R9755 | T14836 | T14835 | pobj | part,in |
R9756 | T14837 | T14822 | punct | ",",suggest |
R9757 | T14838 | T14822 | prep | via,suggest |
R9758 | T14839 | T14841 | det | a,shift |
R9759 | T14840 | T14841 | amod | rapid,shift |
R9760 | T14841 | T14838 | pobj | shift,via |
R9761 | T14842 | T14841 | prep | from,shift |
R9762 | T14843 | T14842 | pobj | NFκB,from |
R9763 | T14844 | T14822 | punct | -,suggest |
R9764 | T14845 | T14846 | aux | to,PI3K-signaling |
R9765 | T14846 | T14822 | xcomp | PI3K-signaling,suggest |
R9767 | T14847 | T14849 | compound | [,] |
R9768 | T14848 | T14849 | compound | "22,37",] |
R9769 | T14849 | T14846 | appos | ],PI3K-signaling |
R9770 | T14850 | T14822 | punct | .,suggest |
R9771 | T14851 | T14852 | poss | Our,study |
R9773 | T14852 | T14853 | nsubj | study,provides |
R9774 | T14853 | T14853 | ROOT | provides,provides |
R9775 | T14854 | T14855 | amod | novel,evidence |
R9776 | T14855 | T14853 | dobj | evidence,provides |
R9777 | T14856 | T14873 | mark | that,switched |
R9779 | T14857 | T14868 | amod | downstream,expression |
R9780 | T14858 | T14857 | prep | of,downstream |
R9781 | T14859 | T14858 | pobj | recognition,of |
R9782 | T14860 | T14857 | cc | and,downstream |
R9784 | T14861 | T14868 | amod | signaling,expression |
R9786 | T14862 | T14864 | amod | pro-inflammatory,factor |
R9787 | T14863 | T14864 | compound | transcription,factor |
R9788 | T14864 | T14865 | nsubj | factor,binding |
R9789 | T14865 | T14861 | ccomp | binding,signaling |
R9790 | T14866 | T14865 | cc | and,binding |
R9791 | T14867 | T14865 | conj | cytokine,binding |
R9792 | T14868 | T14873 | nsubjpass | expression,switched |
R9794 | T14869 | T14868 | prep | of,expression |
R9795 | T14870 | T14871 | amod | human,leukocytes |
R9796 | T14871 | T14869 | pobj | leukocytes,of |
R9799 | T14872 | T14873 | auxpass | is,switched |
R9800 | T14873 | T14855 | acl | switched,evidence |
R9801 | T14874 | T14873 | prep | to,switched |
R9802 | T14875 | T14877 | det | an,phenotype |
R9803 | T14876 | T14877 | amod | anti-inflammatory,phenotype |
R9804 | T14877 | T14874 | pobj | phenotype,to |
R9806 | T14878 | T14877 | prep | by,phenotype |
R9807 | T14879 | T14878 | pobj | GP,by |
R9808 | T14880 | T14853 | punct | .,provides |
bionlp-st-ge-2016-test-tees
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T11940 | 161-165 | Protein | denotes | PI3K |
T11939 | 152-156 | Protein | denotes | NFκB |