PMC:1472690 / 1914-2255 JSONTXT

{"project":"bionlp-st-ge-2016-test-proteins","denotations":[{"id":"T331","span":{"begin":188,"end":194},"obj":"Protein"},{"id":"T332","span":{"begin":285,"end":291},"obj":"Protein"}],"namespaces":[{"prefix":"_base","uri":"http://bionlp.dbcls.jp/ontology/ge.owl#"}],"text":"Thus, β-1→3-D-glucans may induce beneficial effects in the presence of pro-inflammatory responses, downstream of receptor binding and signaling by switching a pro- to an anti-inflammatory IL-1RA-mediated reaction. Our results also offer new insights into the complex regulation of the IL-1RA gene, which can be modulated by a β-1→3-D-glucan."}

{"project":"bionlp-st-ge-2016-uniprot","denotations":[{"id":"T447","span":{"begin":188,"end":194},"obj":"http://www.uniprot.org/uniprot/P18510"},{"id":"T448","span":{"begin":285,"end":291},"obj":"http://www.uniprot.org/uniprot/P18510"}],"namespaces":[{"prefix":"_base","uri":"http://www.uniprot.org/uniprot/"}],"text":"Thus, β-1→3-D-glucans may induce beneficial effects in the presence of pro-inflammatory responses, downstream of receptor binding and signaling by switching a pro- to an anti-inflammatory IL-1RA-mediated reaction. Our results also offer new insights into the complex regulation of the IL-1RA gene, which can be modulated by a β-1→3-D-glucan."}

{"project":"GO-BP","denotations":[{"id":"T219","span":{"begin":75,"end":97},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T222","span":{"begin":134,"end":143},"obj":"http://purl.obolibrary.org/obo/GO_0023052"},{"id":"T223","span":{"begin":267,"end":277},"obj":"http://purl.obolibrary.org/obo/GO_0065007"}],"text":"Thus, β-1→3-D-glucans may induce beneficial effects in the presence of pro-inflammatory responses, downstream of receptor binding and signaling by switching a pro- to an anti-inflammatory IL-1RA-mediated reaction. Our results also offer new insights into the complex regulation of the IL-1RA gene, which can be modulated by a β-1→3-D-glucan."}

{"project":"GO-MF","denotations":[{"id":"T341","span":{"begin":122,"end":129},"obj":"http://purl.obolibrary.org/obo/GO_0005488"},{"id":"T349","span":{"begin":326,"end":340},"obj":"http://purl.obolibrary.org/obo/GO_0001872"},{"id":"T355","span":{"begin":113,"end":129},"obj":"http://purl.obolibrary.org/obo/GO_0005102"}],"text":"Thus, β-1→3-D-glucans may induce beneficial effects in the presence of pro-inflammatory responses, downstream of receptor binding and signaling by switching a pro- to an anti-inflammatory IL-1RA-mediated reaction. Our results also offer new insights into the complex regulation of the IL-1RA gene, which can be modulated by a β-1→3-D-glucan."}

{"project":"sentences","denotations":[{"id":"T204","span":{"begin":0,"end":213},"obj":"Sentence"},{"id":"T205","span":{"begin":214,"end":341},"obj":"Sentence"},{"id":"T18","span":{"begin":0,"end":213},"obj":"Sentence"},{"id":"T19","span":{"begin":214,"end":341},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Thus, β-1→3-D-glucans may induce beneficial effects in the presence of pro-inflammatory responses, downstream of receptor binding and signaling by switching a pro- to an anti-inflammatory IL-1RA-mediated reaction. Our results also offer new insights into the complex regulation of the IL-1RA gene, which can be modulated by a β-1→3-D-glucan."}

{"project":"simple1","denotations":[{"id":"T424","span":{"begin":188,"end":194},"obj":"Protein"},{"id":"T425","span":{"begin":285,"end":291},"obj":"Protein"}],"text":"Thus, β-1→3-D-glucans may induce beneficial effects in the presence of pro-inflammatory responses, downstream of receptor binding and signaling by switching a pro- to an anti-inflammatory IL-1RA-mediated reaction. Our results also offer new insights into the complex regulation of the IL-1RA gene, which can be modulated by a β-1→3-D-glucan."}

{"project":"BioNLP16_DUT","denotations":[{"id":"T856","span":{"begin":188,"end":194},"obj":"Protein"},{"id":"T857","span":{"begin":285,"end":291},"obj":"Protein"},{"id":"T880","span":{"begin":311,"end":320},"obj":"Regulation"},{"id":"T881","span":{"begin":267,"end":277},"obj":"Regulation"}],"relations":[{"id":"R209","pred":"themeOf","subj":"T857","obj":"T881"},{"id":"R225","pred":"themeOf","subj":"T881","obj":"T880"}],"text":"Thus, β-1→3-D-glucans may induce beneficial effects in the presence of pro-inflammatory responses, downstream of receptor binding and signaling by switching a pro- to an anti-inflammatory IL-1RA-mediated reaction. Our results also offer new insights into the complex regulation of the IL-1RA gene, which can be modulated by a β-1→3-D-glucan."}

{"project":"BioNLP16_Messiy","denotations":[{"id":"T482","span":{"begin":188,"end":194},"obj":"Protein"},{"id":"T483","span":{"begin":285,"end":291},"obj":"Protein"},{"id":"T506","span":{"begin":267,"end":277},"obj":"Regulation"}],"relations":[{"id":"R121","pred":"themeOf","subj":"T483","obj":"T506"}],"text":"Thus, β-1→3-D-glucans may induce beneficial effects in the presence of pro-inflammatory responses, downstream of receptor binding and signaling by switching a pro- to an anti-inflammatory IL-1RA-mediated reaction. Our results also offer new insights into the complex regulation of the IL-1RA gene, which can be modulated by a β-1→3-D-glucan."}

{"project":"DLUT931","denotations":[{"id":"T602","span":{"begin":188,"end":194},"obj":"Protein"},{"id":"T603","span":{"begin":285,"end":291},"obj":"Protein"},{"id":"T625","span":{"begin":267,"end":277},"obj":"Regulation"},{"id":"T626","span":{"begin":311,"end":320},"obj":"Regulation"}],"relations":[{"id":"R140","pred":"themeOf","subj":"T603","obj":"T625"},{"id":"R155","pred":"themeOf","subj":"T625","obj":"T626"}],"text":"Thus, β-1→3-D-glucans may induce beneficial effects in the presence of pro-inflammatory responses, downstream of receptor binding and signaling by switching a pro- to an anti-inflammatory IL-1RA-mediated reaction. Our results also offer new insights into the complex regulation of the IL-1RA gene, which can be modulated by a β-1→3-D-glucan."}

{"project":"bionlp-st-ge-2016-test-ihmc","denotations":[{"id":"T791","span":{"begin":167,"end":203},"obj":"Entity"},{"id":"T807","span":{"begin":147,"end":203},"obj":"Entity"},{"id":"T808","span":{"begin":285,"end":291},"obj":"Protein"},{"id":"T746","span":{"begin":278,"end":297},"obj":"Protein"},{"id":"T757","span":{"begin":113,"end":121},"obj":"Protein"},{"id":"T820","span":{"begin":113,"end":129},"obj":"Binding"}],"relations":[{"id":"R334","pred":"themeOf","subj":"T757","obj":"T820"}],"text":"Thus, β-1→3-D-glucans may induce beneficial effects in the presence of pro-inflammatory responses, downstream of receptor binding and signaling by switching a pro- to an anti-inflammatory IL-1RA-mediated reaction. Our results also offer new insights into the complex regulation of the IL-1RA gene, which can be modulated by a β-1→3-D-glucan."}

{"project":"bionlp-st-ge-2016-test-tees","denotations":[{"id":"T568","span":{"begin":285,"end":296},"obj":"Protein"},{"id":"T569","span":{"begin":267,"end":277},"obj":"Regulation"}],"relations":[{"id":"R296","pred":"themeOf","subj":"T568","obj":"T569"}],"text":"Thus, β-1→3-D-glucans may induce beneficial effects in the presence of pro-inflammatory responses, downstream of receptor binding and signaling by switching a pro- to an anti-inflammatory IL-1RA-mediated reaction. Our results also offer new insights into the complex regulation of the IL-1RA gene, which can be modulated by a β-1→3-D-glucan."}

{"project":"testone","denotations":[{"id":"T67","span":{"begin":188,"end":194},"obj":"Protein"},{"id":"T68","span":{"begin":285,"end":291},"obj":"Protein"},{"id":"T94","span":{"begin":267,"end":277},"obj":"Regulation"},{"id":"T95","span":{"begin":311,"end":320},"obj":"Regulation"}],"relations":[{"id":"R21","pred":"themeOf","subj":"T68","obj":"T94"},{"id":"R39","pred":"themeOf","subj":"T94","obj":"T95"}],"text":"Thus, β-1→3-D-glucans may induce beneficial effects in the presence of pro-inflammatory responses, downstream of receptor binding and signaling by switching a pro- to an anti-inflammatory IL-1RA-mediated reaction. Our results also offer new insights into the complex regulation of the IL-1RA gene, which can be modulated by a β-1→3-D-glucan."}

{"project":"test3","denotations":[{"id":"T128","span":{"begin":188,"end":194},"obj":"Protein"},{"id":"T129","span":{"begin":285,"end":291},"obj":"Protein"},{"id":"T184","span":{"begin":188,"end":194},"obj":"Protein"},{"id":"T185","span":{"begin":267,"end":277},"obj":"Regulation"},{"id":"T186","span":{"begin":285,"end":291},"obj":"Protein"}],"relations":[{"id":"R75","pred":"themeOf","subj":"T186","obj":"T185"}],"text":"Thus, β-1→3-D-glucans may induce beneficial effects in the presence of pro-inflammatory responses, downstream of receptor binding and signaling by switching a pro- to an anti-inflammatory IL-1RA-mediated reaction. Our results also offer new insights into the complex regulation of the IL-1RA gene, which can be modulated by a β-1→3-D-glucan."}