LocRepeat accepts three kinds of sequence: DNA, RNA and Protein. The user can either click 'New Data' button to directly input the sequence at the input area, or click 'Input Data from File' button to input a sequence from a file. The user can click 'Set Parameters' button to set parameters, such as granularity factor, gap penalty and similarity score matrix. After the sequence is input and the parameters are set, click the 'Start' button to begin the computation.