PMC:1440874 / 7139-7510
Annnotations
craft-sa-dev
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that removed exon 18 of the Atrx gene. Exon 18 encodes the first of the seven motifs composing the conserved SNF2-like domain of Atrx (Figure 1); mutation of the corresponding motif of the yeast SNF2 protein has been shown to severely impair SWI/SNF-dependent gene expression [12]. The failure to recover targeted clones with these vectors suggested that Atrx may be "}
craft-ca-core-ex-dev
{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T1483","span":{"begin":17,"end":21},"obj":"SO_EXT:0000147"},{"id":"T1484","span":{"begin":32,"end":36},"obj":"PR_EXT:000004503"},{"id":"T1485","span":{"begin":37,"end":41},"obj":"SO_EXT:0000704"},{"id":"T1486","span":{"begin":43,"end":47},"obj":"SO_EXT:0000147"},{"id":"T1487","span":{"begin":51,"end":58},"obj":"SO_EXT:sequence_coding_function"},{"id":"T1488","span":{"begin":82,"end":88},"obj":"SO_EXT:sequence_or_structure_motif"},{"id":"T1489","span":{"begin":103,"end":112},"obj":"SO_EXT:biological_conservation_process_or_quality"},{"id":"T1490","span":{"begin":113,"end":117},"obj":"PR_EXT:P22082"},{"id":"T1491","span":{"begin":123,"end":129},"obj":"SO_EXT:0000417"},{"id":"T1492","span":{"begin":133,"end":137},"obj":"PR_EXT:000004503"},{"id":"T1493","span":{"begin":150,"end":158},"obj":"SO_EXT:sequence_alteration_entity_or_process"},{"id":"T1494","span":{"begin":180,"end":185},"obj":"SO_EXT:sequence_or_structure_motif"},{"id":"T1495","span":{"begin":193,"end":198},"obj":"NCBITaxon_EXT:yeast"},{"id":"T1496","span":{"begin":199,"end":203},"obj":"PR_EXT:P22082"},{"id":"T1497","span":{"begin":204,"end":211},"obj":"CHEBI_PR_EXT:protein"},{"id":"T1498","span":{"begin":246,"end":253},"obj":"GO:0016514"},{"id":"T1499","span":{"begin":264,"end":268},"obj":"SO_EXT:0000704"},{"id":"T1500","span":{"begin":264,"end":279},"obj":"GO:0010467"},{"id":"T1501","span":{"begin":318,"end":324},"obj":"SO_EXT:sequence_cloned_entity"},{"id":"T1502","span":{"begin":336,"end":343},"obj":"SO_EXT:0000440"},{"id":"T1503","span":{"begin":359,"end":363},"obj":"PR_EXT:000004503"}],"text":"ors that removed exon 18 of the Atrx gene. Exon 18 encodes the first of the seven motifs composing the conserved SNF2-like domain of Atrx (Figure 1); mutation of the corresponding motif of the yeast SNF2 protein has been shown to severely impair SWI/SNF-dependent gene expression [12]. The failure to recover targeted clones with these vectors suggested that Atrx may be "}
2_test
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craft-ca-core-dev
{"project":"craft-ca-core-dev","denotations":[{"id":"T1403","span":{"begin":17,"end":21},"obj":"SO:0000147"},{"id":"T1404","span":{"begin":32,"end":36},"obj":"PR:000004503"},{"id":"T1405","span":{"begin":37,"end":41},"obj":"SO:0000704"},{"id":"T1406","span":{"begin":43,"end":47},"obj":"SO:0000147"},{"id":"T1407","span":{"begin":113,"end":117},"obj":"PR:P22082"},{"id":"T1408","span":{"begin":123,"end":129},"obj":"SO:0000417"},{"id":"T1409","span":{"begin":133,"end":137},"obj":"PR:000004503"},{"id":"T1410","span":{"begin":199,"end":203},"obj":"PR:P22082"},{"id":"T1411","span":{"begin":246,"end":253},"obj":"GO:0016514"},{"id":"T1412","span":{"begin":264,"end":268},"obj":"SO:0000704"},{"id":"T1413","span":{"begin":264,"end":279},"obj":"GO:0010467"},{"id":"T1414","span":{"begin":336,"end":343},"obj":"SO:0000440"},{"id":"T1415","span":{"begin":359,"end":363},"obj":"PR:000004503"}],"text":"ors that removed exon 18 of the Atrx gene. Exon 18 encodes the first of the seven motifs composing the conserved SNF2-like domain of Atrx (Figure 1); mutation of the corresponding motif of the yeast SNF2 protein has been shown to severely impair SWI/SNF-dependent gene expression [12]. The failure to recover targeted clones with these vectors suggested that Atrx may be "}