Escape from Imprinted Inactivation of the Paternally Inherited AtrxWT Allele in Carrier Females
Paraffin sections of wild-type (Atrx WT/Y) and carrier female (Atrx WT/null) 7.5 dpc embryos (dissected in their deciduas) were stained with the anti-ATRX antibody (H-300). Scale bars represent 200 μm (40× magnification) or 20 μm (400× magnification).
(A) Stained sections showing whole embryos at 40× magnification. a, amnion; c, chorion; e, epiblast; ep, ectoplacental cone.
(B) Higher-magnification image (400×) of the epiblast regions of the stained sections shown in (A).
(C) Higher-magnification image (400×) showing the extraembryonic derived-chorionic ectoderm of the stained sections shown in (A). ce, chorionic ectoderm; cm, chorionic mesoderm.