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PMC:1440874 / 20297-21215 JSONTXT

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craft-sa-dev

Id Subject Object Predicate Lexical cue
T4246 0-2 TO denotes To
T4247 3-11 VB denotes generate
T4248 75-80 VBN denotes mated
T4249 12-20 JJ denotes Atrxnull
T4250 21-25 NNS denotes mice
T4251 25-27 , denotes ,
T4252 27-39 JJ denotes heterozygous
T4253 47-54 NNS denotes females
T4254 40-46 VBN denotes floxed
T4255 55-56 -LRB- denotes (
T4256 64-68 NN denotes flox
T4257 56-63 NN denotes Atrx WT
T4258 63-64 HYPH denotes /
T4259 68-69 -RRB- denotes )
T4260 70-74 VBD denotes were
T4261 81-85 IN denotes with
T4262 86-96 JJ denotes homozygous
T4263 118-123 NNS denotes males
T4264 97-102 NN denotes GATA1
T4265 103-106 NN denotes cre
T4266 102-103 HYPH denotes -
T4267 107-117 JJ denotes transgenic
T4268 124-125 -LRB- denotes (
T4269 141-144 NN denotes cre
T4270 125-132 NN denotes Atrx WT
T4271 133-134 NN denotes Y
T4272 132-133 HYPH denotes /
T4273 134-135 : denotes ;
T4274 135-140 NN denotes GATA1
T4275 140-141 HYPH denotes -
T4276 145-146 SYM denotes +
T4277 146-147 HYPH denotes /
T4278 147-148 SYM denotes +
T4279 149-150 -RRB- denotes )
T4280 150-151 . denotes .
T4281 151-291 sentence denotes No Atrxnull males (Atrx null/Y;GATA1-cre +/− ) were recovered at birth, indicating that the absence of Atrx results in embryonic lethality.
T4282 152-154 DT denotes No
T4283 164-169 NNS denotes males
T4284 155-163 JJ denotes Atrxnull
T4285 204-213 VBN denotes recovered
T4286 170-171 -LRB- denotes (
T4287 189-192 NN denotes cre
T4288 171-180 NN denotes Atrx null
T4289 181-182 NN denotes Y
T4290 180-181 HYPH denotes /
T4291 182-183 : denotes ;
T4292 183-188 NN denotes GATA1
T4293 188-189 HYPH denotes -
T4294 193-194 SYM denotes +
T4295 194-195 HYPH denotes /
T4296 195-196 SYM denotes −
T4297 197-198 -RRB- denotes )
T4298 199-203 VBD denotes were
T4299 214-216 IN denotes at
T4300 217-222 NN denotes birth
T4301 222-224 , denotes ,
T4302 224-234 VBG denotes indicating
T4303 235-239 IN denotes that
T4304 260-267 VBZ denotes results
T4305 240-243 DT denotes the
T4306 244-251 NN denotes absence
T4307 252-254 IN denotes of
T4308 255-259 NN denotes Atrx
T4309 268-270 IN denotes in
T4310 271-280 JJ denotes embryonic
T4311 281-290 NN denotes lethality
T4312 290-291 . denotes .
T4313 291-394 sentence denotes This finding was unexpected, since human ATR-X patients clearly survive to adulthood (see Discussion).
T4314 292-296 DT denotes This
T4315 297-304 NN denotes finding
T4316 305-308 VBD denotes was
T4317 309-319 JJ denotes unexpected
T4318 319-321 , denotes ,
T4319 321-326 IN denotes since
T4320 356-363 VBP denotes survive
T4321 327-332 JJ denotes human
T4322 339-347 NNS denotes patients
T4323 333-336 NN denotes ATR
T4324 337-338 NN denotes X
T4325 336-337 HYPH denotes -
T4326 348-355 RB denotes clearly
T4327 364-366 IN denotes to
T4328 367-376 NN denotes adulthood
T4329 377-378 -LRB- denotes (
T4330 378-381 VB denotes see
T4331 382-392 NN denotes Discussion
T4332 392-393 -RRB- denotes )
T4333 393-394 . denotes .
T4334 394-548 sentence denotes Embryos were dissected at 7.5, 8.5, and 9.5 dpc and genotyped by PCR analysis of DNA extracted from yolk sac or total embryo (Figure 4B and Protocol S1).
T4335 395-402 NNS denotes Embryos
T4336 408-417 VBN denotes dissected
T4337 403-407 VBD denotes were
T4338 418-420 IN denotes at
T4339 421-424 CD denotes 7.5
T4340 439-442 NN denotes dpc
T4341 424-426 , denotes ,
T4342 426-429 CD denotes 8.5
T4343 429-431 , denotes ,
T4344 431-434 CC denotes and
T4345 435-438 CD denotes 9.5
T4346 443-446 CC denotes and
T4347 447-456 VBN denotes genotyped
T4348 457-459 IN denotes by
T4349 460-463 NN denotes PCR
T4350 464-472 NN denotes analysis
T4351 473-475 IN denotes of
T4352 476-479 NN denotes DNA
T4353 480-489 VBN denotes extracted
T4354 490-494 IN denotes from
T4355 495-499 NN denotes yolk
T4356 500-503 NN denotes sac
T4357 504-506 CC denotes or
T4358 507-512 JJ denotes total
T4359 513-519 NN denotes embryo
T4360 520-521 -LRB- denotes (
T4361 528-530 NN denotes 4B
T4362 521-527 NN denotes Figure
T4363 531-534 CC denotes and
T4364 535-543 NN denotes Protocol
T4365 544-546 NN denotes S1
T4366 546-547 -RRB- denotes )
T4367 547-548 . denotes .
T4368 548-651 sentence denotes Atrxnull males were present at expected mendelian ratios (~25%) at both 7.5 dpc and 8.5 dpc (Table 1).
T4369 549-557 JJ denotes Atrxnull
T4370 558-563 NNS denotes males
T4371 564-568 VBD denotes were
T4372 569-576 JJ denotes present
T4373 577-579 IN denotes at
T4374 580-588 VBN denotes expected
T4375 599-605 NNS denotes ratios
T4376 589-598 JJ denotes mendelian
T4377 606-607 -LRB- denotes (
T4378 610-611 NN denotes %
T4379 607-608 SYM denotes ~
T4380 608-610 CD denotes 25
T4381 611-612 -RRB- denotes )
T4382 613-615 IN denotes at
T4383 616-620 CC denotes both
T4384 625-628 NN denotes dpc
T4385 621-624 CD denotes 7.5
T4386 629-632 CC denotes and
T4387 633-636 CD denotes 8.5
T4388 637-640 NN denotes dpc
T4389 641-642 -LRB- denotes (
T4390 642-647 NN denotes Table
T4391 648-649 CD denotes 1
T4392 649-650 -RRB- denotes )
T4393 650-651 . denotes .
T4394 651-787 sentence denotes However, by 9.5 dpc, depletion was observed both in the number of Atrxnull males (7%) and in the total number of males recovered (31%).
T4395 652-659 RB denotes However
T4396 687-695 VBN denotes observed
T4397 659-661 , denotes ,
T4398 661-663 IN denotes by
T4399 664-667 CD denotes 9.5
T4400 668-671 NN denotes dpc
T4401 671-673 , denotes ,
T4402 673-682 NN denotes depletion
T4403 683-686 VBD denotes was
T4404 696-700 CC denotes both
T4405 701-703 IN denotes in
T4406 704-707 DT denotes the
T4407 708-714 NN denotes number
T4408 715-717 IN denotes of
T4409 718-726 JJ denotes Atrxnull
T4410 727-732 NNS denotes males
T4411 733-734 -LRB- denotes (
T4412 735-736 NN denotes %
T4413 734-735 CD denotes 7
T4414 736-737 -RRB- denotes )
T4415 738-741 CC denotes and
T4416 742-744 IN denotes in
T4417 745-748 DT denotes the
T4418 755-761 NN denotes number
T4419 749-754 JJ denotes total
T4420 762-764 IN denotes of
T4421 765-770 NNS denotes males
T4422 771-780 VBN denotes recovered
T4423 781-782 -LRB- denotes (
T4424 784-785 NN denotes %
T4425 782-784 CD denotes 31
T4426 785-786 -RRB- denotes )
T4427 786-787 . denotes .
T4428 787-835 sentence denotes No Atrxnull males were recovered after 9.5 dpc.
T4429 788-790 DT denotes No
T4430 800-805 NNS denotes males
T4431 791-799 JJ denotes Atrxnull
T4432 811-820 VBN denotes recovered
T4433 806-810 VBD denotes were
T4434 821-826 IN denotes after
T4435 827-830 CD denotes 9.5
T4436 831-834 NN denotes dpc
T4437 834-835 . denotes .
T4438 835-918 sentence denotes Thus the absence of Atrx gives rise to embryonic lethality in mice before 9.5 dpc.
T4439 836-840 RB denotes Thus
T4440 861-866 VBZ denotes gives
T4441 841-844 DT denotes the
T4442 845-852 NN denotes absence
T4443 853-855 IN denotes of
T4444 856-860 NN denotes Atrx
T4445 867-871 NN denotes rise
T4446 872-874 IN denotes to
T4447 875-884 JJ denotes embryonic
T4448 885-894 NN denotes lethality
T4449 895-897 IN denotes in
T4450 898-902 NNS denotes mice
T4451 903-909 IN denotes before
T4452 910-913 CD denotes 9.5
T4453 914-917 NN denotes dpc
T4454 917-918 . denotes .
R2377 T4246 T4247 aux To,generate
R2378 T4247 T4248 advcl generate,mated
R2379 T4249 T4250 amod Atrxnull,mice
R2380 T4250 T4247 dobj mice,generate
R2381 T4251 T4248 punct ", ",mated
R2382 T4252 T4253 amod heterozygous,females
R2383 T4253 T4248 nsubjpass females,mated
R2384 T4254 T4253 amod floxed,females
R2385 T4255 T4256 punct (,flox
R2386 T4256 T4253 parataxis flox,females
R2387 T4257 T4256 compound Atrx WT,flox
R2388 T4258 T4256 punct /,flox
R2389 T4259 T4256 punct ),flox
R2390 T4260 T4248 auxpass were,mated
R2391 T4261 T4248 prep with,mated
R2392 T4262 T4263 amod homozygous,males
R2393 T4263 T4261 pobj males,with
R2394 T4264 T4265 compound GATA1,cre
R2395 T4265 T4267 npadvmod cre,transgenic
R2396 T4266 T4265 punct -,cre
R2397 T4267 T4263 amod transgenic,males
R2398 T4268 T4269 punct (,cre
R2399 T4269 T4263 parataxis cre,males
R2400 T4270 T4271 compound Atrx WT,Y
R2401 T4271 T4269 dep Y,cre
R2402 T4272 T4271 punct /,Y
R2403 T4273 T4269 punct ;,cre
R2404 T4274 T4269 compound GATA1,cre
R2405 T4275 T4269 punct -,cre
R2406 T4276 T4269 punct +,cre
R2407 T4277 T4269 punct /,cre
R2408 T4278 T4269 punct +,cre
R2409 T4279 T4269 punct ),cre
R2410 T4280 T4248 punct .,mated
R2411 T4282 T4283 det No,males
R2412 T4283 T4285 nsubjpass males,recovered
R2413 T4284 T4283 amod Atrxnull,males
R2414 T4286 T4287 punct (,cre
R2415 T4287 T4283 parataxis cre,males
R2416 T4288 T4289 compound Atrx null,Y
R2417 T4289 T4287 dep Y,cre
R2418 T4290 T4289 punct /,Y
R2419 T4291 T4287 punct ;,cre
R2420 T4292 T4287 compound GATA1,cre
R2421 T4293 T4287 punct -,cre
R2422 T4294 T4287 punct +,cre
R2423 T4295 T4287 punct /,cre
R2424 T4296 T4287 punct −,cre
R2425 T4297 T4287 punct ),cre
R2426 T4298 T4285 auxpass were,recovered
R2427 T4299 T4285 prep at,recovered
R2428 T4300 T4299 pobj birth,at
R2429 T4301 T4285 punct ", ",recovered
R2430 T4302 T4285 advcl indicating,recovered
R2431 T4303 T4304 mark that,results
R2432 T4304 T4302 ccomp results,indicating
R2433 T4305 T4306 det the,absence
R2434 T4306 T4304 nsubj absence,results
R2435 T4307 T4306 prep of,absence
R2436 T4308 T4307 pobj Atrx,of
R2437 T4309 T4304 prep in,results
R2438 T4310 T4311 amod embryonic,lethality
R2439 T4311 T4309 pobj lethality,in
R2440 T4312 T4285 punct .,recovered
R2441 T4314 T4315 det This,finding
R2442 T4315 T4316 nsubj finding,was
R2443 T4317 T4316 acomp unexpected,was
R2444 T4318 T4316 punct ", ",was
R2445 T4319 T4320 mark since,survive
R2446 T4320 T4316 advcl survive,was
R2447 T4321 T4322 amod human,patients
R2448 T4322 T4320 nsubj patients,survive
R2449 T4323 T4324 compound ATR,X
R2450 T4324 T4322 compound X,patients
R2451 T4325 T4324 punct -,X
R2452 T4326 T4320 advmod clearly,survive
R2453 T4327 T4320 prep to,survive
R2454 T4328 T4327 pobj adulthood,to
R2455 T4329 T4330 punct (,see
R2456 T4330 T4320 parataxis see,survive
R2457 T4331 T4330 dobj Discussion,see
R2458 T4332 T4330 punct ),see
R2459 T4333 T4316 punct .,was
R2460 T4335 T4336 nsubjpass Embryos,dissected
R2461 T4337 T4336 auxpass were,dissected
R2462 T4338 T4336 prep at,dissected
R2463 T4339 T4340 nummod 7.5,dpc
R2464 T4340 T4338 pobj dpc,at
R2465 T4341 T4339 punct ", ",7.5
R2466 T4342 T4339 conj 8.5,7.5
R2467 T4343 T4342 punct ", ",8.5
R2468 T4344 T4342 cc and,8.5
R2469 T4345 T4342 conj 9.5,8.5
R2470 T4346 T4336 cc and,dissected
R2471 T4347 T4336 conj genotyped,dissected
R2472 T4348 T4347 prep by,genotyped
R2473 T4349 T4350 compound PCR,analysis
R2474 T4350 T4348 pobj analysis,by
R2475 T4351 T4350 prep of,analysis
R2476 T4352 T4351 pobj DNA,of
R2477 T4353 T4352 acl extracted,DNA
R2478 T4354 T4353 prep from,extracted
R2479 T4355 T4356 compound yolk,sac
R2480 T4356 T4354 pobj sac,from
R2481 T4357 T4356 cc or,sac
R2482 T4358 T4359 amod total,embryo
R2483 T4359 T4356 conj embryo,sac
R2484 T4360 T4361 punct (,4B
R2485 T4361 T4336 parataxis 4B,dissected
R2486 T4362 T4361 compound Figure,4B
R2487 T4363 T4361 cc and,4B
R2488 T4364 T4365 compound Protocol,S1
R2489 T4365 T4361 conj S1,4B
R2490 T4366 T4361 punct ),4B
R2491 T4367 T4336 punct .,dissected
R2492 T4369 T4370 amod Atrxnull,males
R2493 T4370 T4371 nsubj males,were
R2494 T4372 T4371 acomp present,were
R2495 T4373 T4371 prep at,were
R2496 T4374 T4375 amod expected,ratios
R2497 T4375 T4373 pobj ratios,at
R2498 T4376 T4375 amod mendelian,ratios
R2499 T4377 T4378 punct (,%
R2500 T4378 T4375 parataxis %,ratios
R2501 T4379 T4380 punct ~,25
R2502 T4380 T4378 nummod 25,%
R2503 T4381 T4378 punct ),%
R2504 T4382 T4371 prep at,were
R2505 T4383 T4384 preconj both,dpc
R2506 T4384 T4382 pobj dpc,at
R2507 T4385 T4384 nummod 7.5,dpc
R2508 T4386 T4384 cc and,dpc
R2509 T4387 T4388 nummod 8.5,dpc
R2510 T4388 T4384 conj dpc,dpc
R2511 T4389 T4390 punct (,Table
R2512 T4390 T4371 parataxis Table,were
R2513 T4391 T4390 nummod 1,Table
R2514 T4392 T4390 punct ),Table
R2515 T4393 T4371 punct .,were
R2516 T4395 T4396 advmod However,observed
R2517 T4397 T4396 punct ", ",observed
R2518 T4398 T4396 prep by,observed
R2519 T4399 T4400 nummod 9.5,dpc
R2520 T4400 T4398 pobj dpc,by
R2521 T4401 T4396 punct ", ",observed
R2522 T4402 T4396 nsubjpass depletion,observed
R2523 T4403 T4396 auxpass was,observed
R2524 T4404 T4405 preconj both,in
R2525 T4405 T4396 prep in,observed
R2526 T4406 T4407 det the,number
R2527 T4407 T4405 pobj number,in
R2528 T4408 T4407 prep of,number
R2529 T4409 T4410 amod Atrxnull,males
R2530 T4410 T4408 pobj males,of
R2531 T4411 T4412 punct (,%
R2532 T4412 T4407 parataxis %,number
R2533 T4413 T4412 nummod 7,%
R2534 T4414 T4412 punct ),%
R2535 T4415 T4405 cc and,in
R2536 T4416 T4405 conj in,in
R2537 T4417 T4418 det the,number
R2538 T4418 T4416 pobj number,in
R2539 T4419 T4418 amod total,number
R2540 T4420 T4418 prep of,number
R2541 T4421 T4420 pobj males,of
R2542 T4422 T4421 acl recovered,males
R2543 T4423 T4424 punct (,%
R2544 T4424 T4418 parataxis %,number
R2545 T4425 T4424 nummod 31,%
R2546 T4426 T4424 punct ),%
R2547 T4427 T4396 punct .,observed
R2548 T4429 T4430 det No,males
R2549 T4430 T4432 nsubjpass males,recovered
R2550 T4431 T4430 amod Atrxnull,males
R2551 T4433 T4432 auxpass were,recovered
R2552 T4434 T4432 prep after,recovered
R2553 T4435 T4436 nummod 9.5,dpc
R2554 T4436 T4434 pobj dpc,after
R2555 T4437 T4432 punct .,recovered
R2556 T4439 T4440 advmod Thus,gives
R2557 T4441 T4442 det the,absence
R2558 T4442 T4440 nsubj absence,gives
R2559 T4443 T4442 prep of,absence
R2560 T4444 T4443 pobj Atrx,of
R2561 T4445 T4440 dobj rise,gives
R2562 T4446 T4440 prep to,gives
R2563 T4447 T4448 amod embryonic,lethality
R2564 T4448 T4446 pobj lethality,to
R2565 T4449 T4440 prep in,gives
R2566 T4450 T4449 pobj mice,in
R2567 T4451 T4440 prep before,gives
R2568 T4452 T4453 nummod 9.5,dpc
R2569 T4453 T4451 pobj dpc,before
R2570 T4454 T4440 punct .,gives

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the bag model. You can change it to the chain model.

Id Subject Object Predicate Lexical cue
T3757 12-16 PR_EXT:000004503 denotes Atrx
T3758 16-20 SO_EXT:sequence_nullness denotes null
T3759 21-25 NCBITaxon:10088 denotes mice
T3760 40-46 SO:0000359 denotes floxed
T3761 47-54 PATO_UBERON_EXT:female_or_bearer_of_femaleness denotes females
T3762 56-60 PR_EXT:000004503 denotes Atrx
T3763 61-63 SO_EXT:wild_type_entity_or_quality denotes WT
T3764 64-68 SO:0000359 denotes flox
T3765 75-80 GO:0007618 denotes mated
T3766 97-102 PR_EXT:000007857 denotes GATA1
T3767 107-117 SO_EXT:transgenic_entity denotes transgenic
T3768 118-123 PATO_UBERON_EXT:male_or_bearer_of_maleness denotes males
T3769 125-129 PR_EXT:000004503 denotes Atrx
T3770 130-132 SO_EXT:wild_type_entity_or_quality denotes WT
T3771 135-140 PR_EXT:000007857 denotes GATA1
T3772 145-146 SO_EXT:normal_or_wild_type_or_present denotes +
T3773 147-148 SO_EXT:normal_or_wild_type_or_present denotes +
T3774 155-159 PR_EXT:000004503 denotes Atrx
T3775 159-163 SO_EXT:sequence_nullness denotes null
T3776 164-169 PATO_UBERON_EXT:male_or_bearer_of_maleness denotes males
T3777 171-175 PR_EXT:000004503 denotes Atrx
T3778 176-180 SO_EXT:sequence_nullness denotes null
T3779 183-188 PR_EXT:000007857 denotes GATA1
T3780 193-194 SO_EXT:normal_or_wild_type_or_present denotes +
T3781 195-196 SO_EXT:sequence_nullness_or_absence denotes −
T3782 217-222 GO:0007567 denotes birth
T3783 255-259 PR_EXT:000004503 denotes Atrx
T3784 271-280 UBERON:0000922 denotes embryonic
T3785 281-290 GO_EXT:fatality_or_lethality denotes lethality
T3786 327-332 NCBITaxon:9606 denotes human
T3787 337-338 GO:0000805 denotes X
T3788 367-376 UBERON:0000113 denotes adulthood
T3789 395-402 UBERON:0000922 denotes Embryos
T3790 476-479 CHEBI_SO_EXT:DNA denotes DNA
T3791 495-503 UBERON:0001040 denotes yolk sac
T3792 513-519 UBERON:0000922 denotes embryo
T3793 549-553 PR_EXT:000004503 denotes Atrx
T3794 553-557 SO_EXT:sequence_nullness denotes null
T3795 558-563 PATO_UBERON_EXT:male_or_bearer_of_maleness denotes males
T3796 718-722 PR_EXT:000004503 denotes Atrx
T3797 722-726 SO_EXT:sequence_nullness denotes null
T3798 727-732 PATO_UBERON_EXT:male_or_bearer_of_maleness denotes males
T3799 765-770 PATO_UBERON_EXT:male_or_bearer_of_maleness denotes males
T3800 791-795 PR_EXT:000004503 denotes Atrx
T3801 795-799 SO_EXT:sequence_nullness denotes null
T3802 800-805 PATO_UBERON_EXT:male_or_bearer_of_maleness denotes males
T3803 856-860 PR_EXT:000004503 denotes Atrx
T3804 875-884 UBERON:0000922 denotes embryonic
T3805 885-894 GO_EXT:fatality_or_lethality denotes lethality
T3806 898-902 NCBITaxon:10088 denotes mice

craft-ca-core-dev

Below, discontinuous spans are shown in the bag model. You can change it to the chain model.

Id Subject Object Predicate Lexical cue
T3543 12-16 PR:000004503 denotes Atrx
T3544 21-25 NCBITaxon:10088 denotes mice
T3545 40-46 SO:0000359 denotes floxed
T3546 56-60 PR:000004503 denotes Atrx
T3547 64-68 SO:0000359 denotes flox
T3548 75-80 GO:0007618 denotes mated
T3549 97-102 PR:000007857 denotes GATA1
T3550 125-129 PR:000004503 denotes Atrx
T3551 135-140 PR:000007857 denotes GATA1
T3552 155-159 PR:000004503 denotes Atrx
T3553 171-175 PR:000004503 denotes Atrx
T3554 183-188 PR:000007857 denotes GATA1
T3555 217-222 GO:0007567 denotes birth
T3556 255-259 PR:000004503 denotes Atrx
T3557 271-280 UBERON:0000922 denotes embryonic
T3558 327-332 NCBITaxon:9606 denotes human
T3559 337-338 GO:0000805 denotes X
T3560 367-376 UBERON:0000113 denotes adulthood
T3561 395-402 UBERON:0000922 denotes Embryos
T3562 495-503 UBERON:0001040 denotes yolk sac
T3563 513-519 UBERON:0000922 denotes embryo
T3564 549-553 PR:000004503 denotes Atrx
T3565 718-722 PR:000004503 denotes Atrx
T3566 791-795 PR:000004503 denotes Atrx
T3567 856-860 PR:000004503 denotes Atrx
T3568 875-884 UBERON:0000922 denotes embryonic
T3569 898-902 NCBITaxon:10088 denotes mice