PMC:138691 / 4119-4788
Annnotations
craft-ca-core-ex-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1776 | 493-506 | GO_SO_EXT:sequence_rearrangement_process | denotes | recombination |
| T1777 | 537-542 | CL_GO_EXT:cell | denotes | cells |
| T1778 | 558-563 | PR_EXT:000004804 | denotes | BRCA2 |
| T1779 | 564-571 | CHEBI_PR_EXT:protein | denotes | protein |
| T1780 | 606-612 | GO:0006281 | denotes | repair |
| T1781 | 617-623 | PR_EXT:P03882 | denotes | I-SceI |
| T1782 | 655-668 | GO_SO_EXT:sequence_rearrangement_process | denotes | recombination |
craft-ca-core-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T958 | 558-563 | PR:000004804 | denotes | BRCA2 |
| T959 | 606-612 | GO:0006281 | denotes | repair |
| T960 | 617-623 | PR:P03882 | denotes | I-SceI |
craft-sa-dev
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1187 | 0-669 | sentence | denotes | Figure 1 Recombination substrates used for assaying homology-directed repair. Cutting at the I-SceI site within the mutant GFP (SceGFP) results in a double-strand break that can be repaired through homologous gene conversion using a 3'-truncated copy of GFP as sequence donor. The mechanism results in the formation of a functional copy of the GFP gene. The model shown assumes gene conversion occurs via the synthesis-dependent annealing mechanism. Moynahan et al [24] have used such a GFP recombination substrate to demonstrate that cells with defective BRCA2 protein are deficient in their ability to repair the I-SceI-induced DSB through homologous recombination. |
| T1188 | 452-460 | NNP | denotes | Moynahan |
| T1189 | 477-481 | VBN | denotes | used |
| T1190 | 461-463 | FW | denotes | et |
| T1191 | 464-466 | FW | denotes | al |
| T1192 | 467-468 | -LRB- | denotes | [ |
| T1193 | 468-470 | CD | denotes | 24 |
| T1194 | 470-471 | -RRB- | denotes | ] |
| T1195 | 472-476 | VBP | denotes | have |
| T1196 | 482-486 | PDT | denotes | such |
| T1197 | 507-516 | NN | denotes | substrate |
| T1198 | 487-488 | DT | denotes | a |
| T1199 | 489-492 | NN | denotes | GFP |
| T1200 | 493-506 | NN | denotes | recombination |
| T1201 | 517-519 | TO | denotes | to |
| T1202 | 520-531 | VB | denotes | demonstrate |
| T1203 | 532-536 | IN | denotes | that |
| T1204 | 572-575 | VBP | denotes | are |
| T1205 | 537-542 | NNS | denotes | cells |
| T1206 | 543-547 | IN | denotes | with |
| T1207 | 548-557 | JJ | denotes | defective |
| T1208 | 564-571 | NN | denotes | protein |
| T1209 | 558-563 | NN | denotes | BRCA2 |
| T1210 | 576-585 | JJ | denotes | deficient |
| T1211 | 586-588 | IN | denotes | in |
| T1212 | 589-594 | PRP$ | denotes | their |
| T1213 | 595-602 | NN | denotes | ability |
| T1214 | 603-605 | TO | denotes | to |
| T1215 | 606-612 | VB | denotes | repair |
| T1216 | 613-616 | DT | denotes | the |
| T1217 | 632-635 | NN | denotes | DSB |
| T1218 | 617-618 | NN | denotes | I |
| T1219 | 619-623 | NN | denotes | SceI |
| T1220 | 618-619 | HYPH | denotes | - |
| T1221 | 624-631 | VBN | denotes | induced |
| T1222 | 623-624 | HYPH | denotes | - |
| T1223 | 636-643 | IN | denotes | through |
| T1224 | 644-654 | JJ | denotes | homologous |
| T1225 | 655-668 | NN | denotes | recombination |
| T1226 | 668-669 | . | denotes | . |
| R738 | T1188 | T1189 | nsubj | Moynahan,used |
| R739 | T1190 | T1191 | advmod | et,al |
| R740 | T1191 | T1188 | advmod | al,Moynahan |
| R741 | T1192 | T1193 | punct | [,24 |
| R742 | T1193 | T1188 | parataxis | 24,Moynahan |
| R743 | T1194 | T1193 | punct | ],24 |
| R744 | T1195 | T1189 | aux | have,used |
| R745 | T1196 | T1197 | predet | such,substrate |
| R746 | T1197 | T1189 | dobj | substrate,used |
| R747 | T1198 | T1197 | det | a,substrate |
| R748 | T1199 | T1200 | compound | GFP,recombination |
| R749 | T1200 | T1197 | compound | recombination,substrate |
| R750 | T1201 | T1202 | aux | to,demonstrate |
| R751 | T1202 | T1189 | advcl | demonstrate,used |
| R752 | T1203 | T1204 | mark | that,are |
| R753 | T1204 | T1202 | ccomp | are,demonstrate |
| R754 | T1205 | T1204 | nsubj | cells,are |
| R755 | T1206 | T1205 | prep | with,cells |
| R756 | T1207 | T1208 | amod | defective,protein |
| R757 | T1208 | T1206 | pobj | protein,with |
| R758 | T1209 | T1208 | compound | BRCA2,protein |
| R759 | T1210 | T1204 | acomp | deficient,are |
| R760 | T1211 | T1210 | prep | in,deficient |
| R761 | T1212 | T1213 | poss | their,ability |
| R762 | T1213 | T1211 | pobj | ability,in |
| R763 | T1214 | T1215 | aux | to,repair |
| R764 | T1215 | T1213 | acl | repair,ability |
| R765 | T1216 | T1217 | det | the,DSB |
| R766 | T1217 | T1215 | dobj | DSB,repair |
| R767 | T1218 | T1219 | compound | I,SceI |
| R768 | T1219 | T1221 | npadvmod | SceI,induced |
| R769 | T1220 | T1219 | punct | -,SceI |
| R770 | T1221 | T1217 | amod | induced,DSB |
| R771 | T1222 | T1221 | punct | -,induced |
| R772 | T1223 | T1215 | prep | through,repair |
| R773 | T1224 | T1225 | amod | homologous,recombination |
| R774 | T1225 | T1223 | pobj | recombination,through |
| R775 | T1226 | T1189 | punct | .,used |