PMC:1382200 / 26035-26729
Annnotations
craft-sa-dev
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T14792 | 693-694 | . | denotes | . |
T14791 | 672-681 | JJ | denotes | embryonic |
T14790 | 682-693 | NN | denotes | development |
T14789 | 666-671 | JJ | denotes | early |
T14788 | 663-665 | IN | denotes | on |
T14787 | 655-662 | NNS | denotes | effects |
T14786 | 648-654 | JJ | denotes | lethal |
T14785 | 638-642 | RB | denotes | both |
T14784 | 632-637 | MD | denotes | would |
T14783 | 609-619 | NN | denotes | chromosome |
T14782 | 620-631 | NN | denotes | segregation |
T14781 | 599-608 | JJ | denotes | defective |
T14780 | 596-598 | CC | denotes | or |
T14779 | 643-647 | VB | denotes | have |
T14778 | 585-595 | NN | denotes | Polyspermy |
T14777 | 584-694 | sentence | denotes | Polyspermy or defective chromosome segregation would both have lethal effects on early embryonic development. |
T14776 | 583-584 | . | denotes | . |
T14775 | 582-583 | -RRB- | denotes | ] |
T14774 | 580-582 | CD | denotes | 45 |
T14773 | 579-580 | -LRB- | denotes | [ |
T14772 | 567-578 | NN | denotes | segregation |
T14771 | 556-566 | NN | denotes | chromosome |
T14770 | 553-555 | IN | denotes | in |
T14769 | 541-543 | VB | denotes | be |
T14768 | 535-540 | MD | denotes | could |
T14767 | 532-534 | PRP | denotes | it |
T14766 | 544-552 | VBN | denotes | involved |
T14765 | 527-531 | VBD | denotes | were |
T14764 | 525-527 | , | denotes | , |
T14763 | 512-525 | NN | denotes | fertilization |
T14762 | 506-511 | IN | denotes | after |
T14761 | 490-497 | JJ | denotes | meiotic |
T14760 | 483-489 | NN | denotes | oocyte |
T14759 | 498-505 | NN | denotes | spindle |
T14758 | 479-482 | DT | denotes | the |
T14757 | 476-478 | IN | denotes | to |
T14756 | 459-463 | RB | denotes | also |
T14755 | 464-475 | VBD | denotes | relocalized |
T14754 | 450-451 | HYPH | denotes | - |
T14753 | 451-458 | NN | denotes | calpain |
T14752 | 449-450 | NN | denotes | m |
T14751 | 448-584 | sentence | denotes | m-calpain also relocalized to the oocyte meiotic spindle after fertilization, were it could be involved in chromosome segregation [45]. |
T14750 | 447-448 | . | denotes | . |
T14749 | 446-447 | -RRB- | denotes | ] |
T14748 | 444-446 | CD | denotes | 45 |
T14747 | 443-444 | -LRB- | denotes | [ |
T14746 | 432-442 | NN | denotes | polyspermy |
T14745 | 424-431 | VB | denotes | prevent |
T14744 | 421-423 | TO | denotes | to |
T14743 | 412-420 | VBN | denotes | required |
T14742 | 395-402 | NN | denotes | granule |
T14741 | 403-411 | NNS | denotes | contents |
T14740 | 386-394 | JJ | denotes | cortical |
T14739 | 383-385 | IN | denotes | of |
T14738 | 375-382 | NN | denotes | release |
T14737 | 371-374 | DT | denotes | the |
T14736 | 368-370 | IN | denotes | in |
T14735 | 350-355 | MD | denotes | might |
T14734 | 347-349 | PRP | denotes | it |
T14733 | 356-367 | VB | denotes | participate |
T14732 | 341-346 | WRB | denotes | where |
T14731 | 333-340 | NNS | denotes | oocytes |
T14730 | 330-332 | IN | denotes | in |
T14729 | 312-320 | JJ | denotes | cortical |
T14728 | 321-329 | NN | denotes | membrane |
T14727 | 308-311 | DT | denotes | the |
T14726 | 305-307 | IN | denotes | to |
T14725 | 296-297 | HYPH | denotes | - |
T14724 | 297-304 | NN | denotes | calpain |
T14723 | 295-296 | NN | denotes | m |
T14722 | 292-294 | IN | denotes | of |
T14721 | 278-291 | NN | denotes | translocation |
T14720 | 276-277 | DT | denotes | a |
T14719 | 271-275 | IN | denotes | with |
T14718 | 260-270 | VBD | denotes | correlated |
T14717 | 254-259 | WDT | denotes | which |
T14716 | 252-253 | -RRB- | denotes | ] |
T14715 | 250-252 | CD | denotes | 47 |
T14714 | 249-250 | -LRB- | denotes | [ |
T14713 | 231-239 | NN | denotes | acrosome |
T14712 | 240-248 | NN | denotes | reaction |
T14711 | 227-230 | DT | denotes | the |
T14710 | 224-226 | IN | denotes | in |
T14709 | 209-212 | VBD | denotes | was |
T14708 | 200-201 | HYPH | denotes | - |
T14707 | 201-208 | NN | denotes | calpain |
T14706 | 199-200 | NN | denotes | m |
T14705 | 197-198 | . | denotes | . |
T14704 | 196-197 | -RRB- | denotes | ] |
T14703 | 194-196 | CD | denotes | 45 |
T14702 | 193-194 | -LRB- | denotes | [ |
T14701 | 185-192 | NNS | denotes | oocytes |
T14700 | 181-184 | CC | denotes | and |
T14699 | 179-180 | -RRB- | denotes | ] |
T14698 | 177-179 | CD | denotes | 47 |
T14697 | 176-177 | -LRB- | denotes | [ |
T14696 | 170-175 | NN | denotes | sperm |
T14695 | 163-169 | NN | denotes | rodent |
T14694 | 160-162 | IN | denotes | in |
T14693 | 213-223 | VBN | denotes | implicated |
T14692 | 146-150 | VBN | denotes | been |
T14691 | 137-145 | RB | denotes | recently |
T14690 | 132-136 | VBP | denotes | have |
T14689 | 151-159 | VBN | denotes | detected |
T14688 | 123-124 | HYPH | denotes | - |
T14687 | 122-123 | NN | denotes | m |
T14686 | 118-121 | CC | denotes | and |
T14685 | 116-117 | HYPH | denotes | - |
T14684 | 124-131 | NN | denotes | calpain |
T14683 | 115-116 | NN | denotes | μ |
T14682 | 110-114 | CC | denotes | Both |
T14681 | 109-448 | sentence | denotes | Both μ- and m-calpain have recently been detected in rodent sperm [47] and oocytes [45]. m-calpain was implicated in the acrosome reaction [47] which correlated with a translocation of m-calpain to the cortical membrane in oocytes where it might participate in the release of cortical granule contents required to prevent polyspermy [45]. |
T14680 | 108-109 | . | denotes | . |
T14679 | 107-108 | -RRB- | denotes | ] |
T14678 | 105-107 | CD | denotes | 46 |
T14677 | 104-105 | -LRB- | denotes | [ |
T14676 | 86-94 | NN | denotes | acrosome |
T14675 | 95-103 | NN | denotes | reaction |
T14674 | 82-85 | DT | denotes | the |
T14673 | 73-81 | VBZ | denotes | triggers |
T14672 | 67-72 | WDT | denotes | which |
T14671 | 47-58 | JJ | denotes | cytoplasmic |
T14670 | 59-66 | NN | denotes | calcium |
T14669 | 37-46 | VBN | denotes | increased |
T14668 | 34-36 | IN | denotes | to |
T14667 | 21-27 | NN | denotes | oocyte |
T14666 | 17-20 | DT | denotes | the |
T14665 | 14-16 | IN | denotes | to |
T14664 | 28-33 | VBZ | denotes | leads |
T14663 | 6-13 | NN | denotes | binding |
T14662 | 0-5 | NN | denotes | Sperm |
R4086 | T14662 | T14663 | compound | Sperm,binding |
R4088 | T14663 | T14664 | nsubj | binding,leads |
R4090 | T14665 | T14663 | prep | to,binding |
R4091 | T14666 | T14667 | det | the,oocyte |
R4092 | T14667 | T14665 | pobj | oocyte,to |
R4094 | T14668 | T14664 | prep | to,leads |
R4095 | T14669 | T14670 | amod | increased,calcium |
R4096 | T14670 | T14668 | pobj | calcium,to |
R4098 | T14671 | T14670 | amod | cytoplasmic,calcium |
R4099 | T14672 | T14673 | dep | which,triggers |
R4100 | T14673 | T14670 | relcl | triggers,calcium |
R4102 | T14674 | T14675 | det | the,reaction |
R4103 | T14675 | T14673 | dobj | reaction,triggers |
R4106 | T14676 | T14675 | compound | acrosome,reaction |
R4108 | T14677 | T14678 | punct | [,46 |
R4109 | T14678 | T14664 | parataxis | 46,leads |
R4110 | T14679 | T14678 | punct | ],46 |
R4112 | T14680 | T14664 | punct | .,leads |
R4113 | T14682 | T14683 | preconj | Both,μ |
R4114 | T14683 | T14684 | nmod | μ,calpain |
R4116 | T14684 | T14689 | nsubjpass | calpain,detected |
R4117 | T14685 | T14683 | punct | -,μ |
R4118 | T14686 | T14683 | cc | and,μ |
R4119 | T14687 | T14683 | conj | m,μ |
R4121 | T14688 | T14684 | punct | -,calpain |
R4122 | T14689 | T14693 | ccomp | detected,implicated |
R4123 | T14690 | T14689 | aux | have,detected |
R4124 | T14691 | T14689 | advmod | recently,detected |
R4125 | T14692 | T14689 | auxpass | been,detected |
R4127 | T14694 | T14689 | prep | in,detected |
R4128 | T14695 | T14696 | compound | rodent,sperm |
R4129 | T14696 | T14694 | pobj | sperm,in |
R4131 | T14697 | T14698 | punct | [,47 |
R4132 | T14698 | T14696 | parataxis | 47,sperm |
R4133 | T14699 | T14698 | punct | ],47 |
R4135 | T14700 | T14696 | cc | and,sperm |
R4136 | T14701 | T14696 | conj | oocytes,sperm |
R4137 | T14702 | T14703 | punct | [,45 |
R4138 | T14781 | T14782 | amod | defective,segregation |
R4139 | T14703 | T14701 | parataxis | 45,oocytes |
R4140 | T14704 | T14703 | punct | ],45 |
R4141 | T14705 | T14689 | punct | .,detected |
R4142 | T14706 | T14707 | compound | m,calpain |
R4143 | T14782 | T14778 | conj | segregation,Polyspermy |
R4144 | T14707 | T14693 | nsubjpass | calpain,implicated |
R4145 | T14708 | T14707 | punct | -,calpain |
R4146 | T14709 | T14693 | auxpass | was,implicated |
R4147 | T14783 | T14782 | compound | chromosome,segregation |
R4148 | T14784 | T14779 | aux | would,have |
R4149 | T14710 | T14693 | prep | in,implicated |
R4150 | T14711 | T14712 | det | the,reaction |
R4151 | T14712 | T14710 | pobj | reaction,in |
R4152 | T14785 | T14779 | advmod | both,have |
R4153 | T14713 | T14712 | compound | acrosome,reaction |
R4154 | T14714 | T14715 | punct | [,47 |
R4155 | T14786 | T14787 | amod | lethal,effects |
R4156 | T14715 | T14712 | parataxis | 47,reaction |
R4157 | T14716 | T14715 | punct | ],47 |
R4158 | T14717 | T14718 | dep | which,correlated |
R4159 | T14718 | T14712 | relcl | correlated,reaction |
R4160 | T14787 | T14779 | dobj | effects,have |
R4161 | T14719 | T14718 | prep | with,correlated |
R4162 | T14720 | T14721 | det | a,translocation |
R4163 | T14788 | T14787 | prep | on,effects |
R4164 | T14721 | T14719 | pobj | translocation,with |
R4165 | T14722 | T14721 | prep | of,translocation |
R4166 | T14789 | T14790 | amod | early,development |
R4167 | T14723 | T14724 | compound | m,calpain |
R4168 | T14724 | T14722 | pobj | calpain,of |
R4169 | T14725 | T14724 | punct | -,calpain |
R4170 | T14790 | T14788 | pobj | development,on |
R4171 | T14726 | T14721 | prep | to,translocation |
R4172 | T14727 | T14728 | det | the,membrane |
R4173 | T14728 | T14726 | pobj | membrane,to |
R4174 | T14729 | T14728 | amod | cortical,membrane |
R4175 | T14730 | T14728 | prep | in,membrane |
R4176 | T14731 | T14730 | pobj | oocytes,in |
R4177 | T14791 | T14790 | amod | embryonic,development |
R4178 | T14732 | T14733 | advmod | where,participate |
R4179 | T14733 | T14728 | relcl | participate,membrane |
R4180 | T14734 | T14733 | nsubj | it,participate |
R4181 | T14792 | T14779 | punct | .,have |
R4182 | T14735 | T14733 | aux | might,participate |
R4183 | T14736 | T14733 | prep | in,participate |
R4184 | T14737 | T14738 | det | the,release |
R4186 | T14738 | T14736 | pobj | release,in |
R4187 | T14739 | T14738 | prep | of,release |
R4188 | T14740 | T14741 | amod | cortical,contents |
R4189 | T14741 | T14739 | pobj | contents,of |
R4191 | T14742 | T14741 | compound | granule,contents |
R4192 | T14743 | T14741 | acl | required,contents |
R4193 | T14744 | T14745 | aux | to,prevent |
R4194 | T14745 | T14743 | advcl | prevent,required |
R4196 | T14746 | T14745 | dobj | polyspermy,prevent |
R4197 | T14747 | T14748 | punct | [,45 |
R4198 | T14748 | T14745 | parataxis | 45,prevent |
R4199 | T14749 | T14748 | punct | ],45 |
R4200 | T14750 | T14693 | punct | .,implicated |
R4202 | T14752 | T14753 | compound | m,calpain |
R4203 | T14753 | T14755 | nsubj | calpain,relocalized |
R4204 | T14754 | T14753 | punct | -,calpain |
R4206 | T14756 | T14755 | advmod | also,relocalized |
R4208 | T14757 | T14755 | prep | to,relocalized |
R4209 | T14758 | T14759 | det | the,spindle |
R4210 | T14759 | T14757 | pobj | spindle,to |
R4212 | T14760 | T14759 | nmod | oocyte,spindle |
R4213 | T14761 | T14759 | amod | meiotic,spindle |
R4214 | T14762 | T14755 | prep | after,relocalized |
R4216 | T14763 | T14762 | pobj | fertilization,after |
R4217 | T14764 | T14755 | punct | ", ",relocalized |
R4219 | T14765 | T14766 | dep | were,involved |
R4220 | T14766 | T14755 | ccomp | involved,relocalized |
R4221 | T14767 | T14766 | nsubjpass | it,involved |
R4223 | T14768 | T14766 | aux | could,involved |
R4224 | T14769 | T14766 | auxpass | be,involved |
R4225 | T14770 | T14766 | prep | in,involved |
R4226 | T14771 | T14772 | compound | chromosome,segregation |
R4227 | T14772 | T14770 | pobj | segregation,in |
R4228 | T14773 | T14774 | punct | [,45 |
R4230 | T14774 | T14766 | parataxis | 45,involved |
R4231 | T14775 | T14774 | punct | ],45 |
R4232 | T14776 | T14755 | punct | .,relocalized |
R4234 | T14778 | T14779 | nsubj | Polyspermy,have |
R4236 | T14780 | T14778 | cc | or,Polyspermy |
craft-ca-core-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T12377 | 672-693 | GO:0009790 | denotes | embryonic development |
T12376 | 666-681 | UBERON:0019248 | denotes | early embryonic |
T12375 | 609-631 | GO:0007059 | denotes | chromosome segregation |
T12374 | 556-578 | GO:0007059 | denotes | chromosome segregation |
T12373 | 512-525 | GO:0009566 | denotes | fertilization |
T12372 | 490-505 | GO:0072687 | denotes | meiotic spindle |
T12371 | 490-497 | GO:0007126 | denotes | meiotic |
T12370 | 483-489 | CL:0000023 | denotes | oocyte |
T12369 | 386-402 | GO:0060473 | denotes | cortical granule |
T12368 | 333-340 | CL:0000023 | denotes | oocytes |
T12367 | 321-329 | GO:0016020 | denotes | membrane |
T12366 | 312-320 | GO:0005938 | denotes | cortical |
T12365 | 231-248 | GO:0007340 | denotes | acrosome reaction |
T12364 | 231-239 | GO:0001669 | denotes | acrosome |
T12363 | 185-192 | CL:0000023 | denotes | oocytes |
T12362 | 170-175 | CL:0000019 | denotes | sperm |
T12361 | 163-169 | NCBITaxon:9989 | denotes | rodent |
T12360 | 86-103 | GO:0007340 | denotes | acrosome reaction |
T12359 | 86-94 | GO:0001669 | denotes | acrosome |
T12358 | 47-58 | GO:0005737 | denotes | cytoplasmic |
T12357 | 21-27 | CL:0000023 | denotes | oocyte |
T12356 | 0-5 | CL:0000019 | denotes | Sperm |
craft-ca-core-ex-dev
Below, discontinuous spans are shown in the chain model. You can change it to the bag model.
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T12750 | 672-693 | GO:0009790 | denotes | embryonic development |
T12749 | 666-681 | UBERON:0019248 | denotes | early embryonic |
T12748 | 648-654 | GO_EXT:fatality_or_lethality | denotes | lethal |
T12747 | 609-631 | GO:0007059 | denotes | chromosome segregation |
T12746 | 609-619 | GO_SO_EXT:chromosome | denotes | chromosome |
T12745 | 556-578 | GO:0007059 | denotes | chromosome segregation |
T12744 | 556-566 | GO_SO_EXT:chromosome | denotes | chromosome |
T12743 | 512-525 | GO:0009566 | denotes | fertilization |
T12742 | 490-505 | GO:0072687 | denotes | meiotic spindle |
T12725 | 163-169 | NCBITaxon:9989 | denotes | rodent |
T12724 | 122-131 | GO_PR_EXT:calpain_2_complex | denotes | m-calpain |
T12723 | 124-131 | GO_PR_EXT:calpain_1_complex | denotes | calpain |
T12722 | 115-117 | _FRAGMENT | denotes | μ- |
T12721 | 86-103 | GO:0007340 | denotes | acrosome reaction |
T12720 | 86-94 | GO:0001669 | denotes | acrosome |
T12719 | 59-66 | CHEBI_EXT:calcium | denotes | calcium |
T12718 | 47-58 | GO:0005737 | denotes | cytoplasmic |
T12717 | 21-27 | CL:0000023 | denotes | oocyte |
T12716 | 6-13 | CHEMINF_GO_EXT:chemical_binding_or_bond_formation | denotes | binding |
T12715 | 0-5 | CL:0000019 | denotes | Sperm |
T12741 | 490-497 | GO:0007126 | denotes | meiotic |
T12740 | 483-489 | CL:0000023 | denotes | oocyte |
T12739 | 466-475 | GO_PATO_EXT:biological_localization_process_or_quality | denotes | localized |
T12738 | 449-458 | GO_PR_EXT:calpain_2_complex | denotes | m-calpain |
T12737 | 386-402 | GO:0060473 | denotes | cortical granule |
T12736 | 375-382 | GO_EXT:biological_release | denotes | release |
T12735 | 333-340 | CL:0000023 | denotes | oocytes |
T12734 | 321-329 | GO:0016020 | denotes | membrane |
T12733 | 312-320 | GO:0005938 | denotes | cortical |
T12732 | 295-304 | GO_PR_EXT:calpain_2_complex | denotes | m-calpain |
T12731 | 278-291 | GO_EXT:biological_translocation_entity_or_process | denotes | translocation |
T12730 | 231-248 | GO:0007340 | denotes | acrosome reaction |
T12729 | 231-239 | GO:0001669 | denotes | acrosome |
T12728 | 199-208 | GO_PR_EXT:calpain_2_complex | denotes | m-calpain |
T12727 | 185-192 | CL:0000023 | denotes | oocytes |
T12726 | 170-175 | CL:0000019 | denotes | sperm |
R2372 | T12723 | T12722 | _lexicallyChainedTo | calpain,μ- |