PMC:1283364 / 66846-67346 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/1283364","sourcedb":"PMC","sourceid":"1283364","source_url":"http://www.ncbi.nlm.nih.gov/pmc/1283364","text":"Arrest of Amyloid Progression by Chronic Transgene Suppression in Line 18 Tet-Off APP Mice\nAmyloid histology in cortical (first and third rows) and hippocampal (second and fourth rows) sections from untreated tTA/APP mice shows a dramatic progression of pathology between 6 and 9 mo of age. Suppression of transgenic APP expression arrests this progression, although without any sign of plaque clearance (6 mo + 3 mo dox). Hirano silver stain (top panels); thioflavin-S (bottom panels).\n(5.8 MB PSD).","divisions":[{"label":"title","span":{"begin":0,"end":90}},{"label":"p","span":{"begin":91,"end":486}}],"tracks":[]}