Experimental groups Mice heterozygous for TgCre4 and heterozygous for the TK-neo cassette in the GluR-B allele (GluR-BΔECS:FB) or homozygous for the floxed GluR-B (GluR-BΔFB) were used in the experiments. The “rescue” mice (GluR-BRescue) were positive for TgCre4, homozygous for the floxed GluR-B gene, and positive for the tet-sensitive responder transgene TgOCN1 and for the itTA expressing activator transgene TgCN12-itTA.