Unadjusted (n = 199)  Adjusted (n = 177)a
Incidence RR (95% CI)b   Incidence RR (95% CI)b
Infection type  2nd quartile (n = 50)  3rd quartile (n = 50)  4th quartile (n = 50)  p-Value for trendc  2nd quartile (n = 40)  3rd quartile (n = 46)  4th quartile (n = 45)  p-Value for trendc
6-Month follow-up
 URTIs  1.08 (0.76–1.55)  0.98 (0.68–1.41)  1.19 (0.84–1.68)  0.69  1.08 (0.69–1.67)  1.08 (0.71–1.65)  1.32 (0.87–2.00)  0.22
 Otitis media  1.33 (0.85–2.07)  1.15 (0.73–1.82)  1.30 (0.83–2.02)  0.17  1.11 (0.65–1.89)  0.99 (0.59–1.66)  1.39 (0.82–2.35)  0.17
 GI infections  1.63 (0.80–3.34)  1.31 (0.62–2.76)  1.55 (0.75–3.20)  0.33  1.89 (0.78–4.56)  1.52 (0.65–3.54)  1.54 (0.66–3.60)  0.38
 LRTIs  1.12 (0.71–1.76)  1.54 (1.01–2.35)*  1.01 (0.63–1.61)  0.61  1.16 (0.65–2.09)  1.68 (1.00–2.81)*  1.18 (0.68–2.04)  0.38
 All infectionsd  1.19 (0.95–1.50)  1.18 (0.94–1.48)  1.19 (0.95–1.50)  0.14  1.17 (0.88–1.55)  1.19 (0.92–1.54)  1.27 (0.98–1.66)  0.04*
12-Month follow-up
 URTIs  0.93 (0.72–1.20)  0.87 (0.67–1.13)  1.12 (0.88–1.43)  0.81  0.99 (0.71–1.36)  0.96 (0.71–1.29)  1.23 (0.92–1.65)  0.29
 Otitis media  1.05 (0.83–1.32)  0.97 (0.76–1.22)  0.94 (0.75–1.20)  0.89  1.02 (0.77–1.35)  0.89 (0.68–1.17)  0.97 (0.73–1.28)  0.89
 GI infections  1.27 (0.86–1.88)  1.22 (0.82–1.82)  1.05 (0.69–1.58)  0.81  1.53 (0.94–2.49)  1.59 (1.01–2.49)*  1.26 (0.78–2.04)  0.29
 LRTIs  0.88 (0.65–1.19)  1.08 (0.81–1.45)  0.96 (0.71–1.29)  0.48  0.86 (0.57–1.28)  1.10 (0.78–1.55)  1.03 (0.72–1.48)  0.36
 All infectionsd  1.00 (0.87–1.15)  0.99 (0.86–1.14)  1.01 (0.88–1.16)  0.67  1.02 (0.86–1.21)  1.01 (0.86–1.19)  1.08 (0.92–1.28)  0.24