PMC:1208879 / 0-572
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craft-sa-dev
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screen for proteins that interact with PAX6: C-terminal mutations disrupt interaction with HOMER3, DNCL1 and TRIM11\n\nAbstract\nBackground\nThe PAX6 protein is a transcriptional regulator with a key role in ocular and neurological development. Individuals with heterozygous loss-of-function mutations in the PAX6 gene have malformations of the eye and brain. Little is known about the interactions of PAX6 with other proteins, so we carried out a systematic screen for proteins that interact with PAX6.\n\nResults\nWe used bioinformatics techniques to characterise a highly co"}
craft-ca-core-ex-dev
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craft-ca-core-dev
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