Statistical Analysis A repeated measures analysis of variance was used to test the effect of treatments on QTc (within subject factor: time of ECG examination, between subject factor: therapy group). Fisher Exact Test was used to compared the number of patients who exceed the threshold of borderline QTc values in Group 1 and Group 2. Indipendent T-Sample Tests were used to test the differences between baseline QTc values, ages and duration of illness using the statistical package Stata 7.0 (Stata Coorporation, 2001).