Tigecycline was the most active antibiotic against MRSA and Enterococci with respect to linezolid (MIC 2 and 0.5 mg/L respectively) and quinopristin/dalfopristin (MIC 0.25 and 0.5 mg/L respectively), and with respect to macrolides, amoxicillin and tetracycline for all Streptococci.