CORD-19:cb16d307afaecebd683e6d74c8b501ed54b0c9a4 / 66588-66909 JSONTXT

{"project":"CORD-19-Sentences","denotations":[{"id":"TextSentencer_T379","span":{"begin":0,"end":321},"obj":"Sentence"},{"id":"T48070","span":{"begin":0,"end":321},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"It is worth noting that the most potent compound 189 (Fig. 19) , in which there were two chiral centers important for inhibitory potency, exerted the strong inhibition with IC 50 value of 0.39 mM, whose activity was 20fold stronger than its enantiomer, indicating the importance of asymmetric [3 þ 2] cyclization process."}

{"project":"CORD-19_Custom_license_subset","denotations":[{"id":"T93","span":{"begin":0,"end":321},"obj":"Sentence"}],"text":"It is worth noting that the most potent compound 189 (Fig. 19) , in which there were two chiral centers important for inhibitory potency, exerted the strong inhibition with IC 50 value of 0.39 mM, whose activity was 20fold stronger than its enantiomer, indicating the importance of asymmetric [3 þ 2] cyclization process."}