The association has antibacterial activity against staphylococci including methicillin */MLS B -resistant strains (MIC90 range: 0.12 */1 mg/ml), streptococci (MIC90: 0.25 mg/ml), pneumococci including multidrug resistant strains (MIC90: 0.50 mg/ ml), enterococci including vancomycin-resistant strains (MIC90: 4 mg/ ml), M. catarrhalis and Neisseria spp.