Baykan a a Istanbul Medical Faculty, Istanbul, Turkey; b University of Texas Medical Branch, Galveston, TX, USA Sera from 4 siblings (aged 24-31 years) with Lafora disease (LD) late onset variant, diagnosed by axillary skin biopsy, who also had high titers of anti-gliadin IgG antibodies were tested by immunohistochemistry for antibodies capable of binding to mouse central nervous system (CNS) antigens.