1 Division of Infectious Diseases, 2 Division of Rheumatology and Immunology, 3 Division of Chest Medicine, 4 Department of Internal Medicine, 5 Department of Intensive Care Medicine, and 6 Department of Laboratory Medicine, Buddhist Tzu Chi General Hospital, Hualien, Taiwan Background: Eosinophilic granulomatosis with polyangiitis (EGPA; also known as Churg-Strauss syndrome) usually presents as recurrent asthma that cannot be controlled without systemic steroids, which, unfortunately, increases the risk of opportunistic infections.