M 53:36, EDSS 1.8 ± 1.3), 34 patients in acute relapse (age 34.1 ± 8.4 years, disease duration 6.0 ± 4.1 years, F:M 25:9, EDSS 3.2 ± 1.3) compared with data from 41 healthy subjects (age 35.5 ± 8.8 years, F: