Furthermore, in our analysis of the data from 2 IRF5 SNPs (rs3807306 and rs4728142), we found association in a combined cohort of our study collections and earlier published data with P values of P CMH = 0.002 [OR = 1.14 (1.05-1.23)] and P CMH = 0.001 [OR = 1.14 (1.05-1.24)] respectively.