However, the same panel of antibodies did not cross-react with PDCoV in our CCIF assays (Lin and Saif, unpublished data) . On the other hand, no virus cross-neutralization activity was observed between PEDV and TGEV, or between PEDV and PDCoV (Lin et al., 2015b; Ma et al., 2016) . If PDCoV is found to be widespread in swine and a factor in enteric disease, it is possible that PDCoV may be included in future multivalent vaccines against swine enteric viral diseases.