In the remaining 8 out of 9 CKD dogs with stage 2, the mean of UP/C was normal (UP/C < 0.4) during the follow-up period, however the qualitative evaluation detected loss of tubular proteins (RBP and /or VDBP) in 2/8, loss of glomerular protein (albumin) in 1/8, loss of tubular and glomerular proteins in 2/8, and in 3/8 no level of proteins were found.